BGC0002672: saccharothrixin D biosynthetic gene cluster from Saccharothrix sp.
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Location: 1 - 31,770 nt. (total: 31,770 nt).
This entry is originally from NCBI GenBank MW386996.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002672
Short description saccharothrixin D biosynthetic gene cluster from Saccharothrix sp.
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
MW386996.1
via Knock-out studies, Heterologous expression
Compounds
  • saccharothrixin D
  • saccharothrixin E
  • saccharothrixin F
  • saccharothrixin G
  • saccharothrixin H
  • saccharothrixin I
  • saccharothrixin J
  • saccharothrixin K
  • saccharothrixin L
  • saccharothrixin M
Species Saccharothrix sp. [taxonomy]
References
Chemical products information
saccharothrixin D Evidence:
(no structure information available)
saccharothrixin E Evidence:
(no structure information available)
saccharothrixin F Evidence:
(no structure information available)
saccharothrixin G Evidence:
(no structure information available)
saccharothrixin H Evidence:
(no structure information available)
saccharothrixin I Evidence:
(no structure information available)
saccharothrixin J Evidence:
(no structure information available)
saccharothrixin K Evidence:
(no structure information available)
saccharothrixin L Evidence:
(no structure information available)
saccharothrixin M Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • UPN68077.1
  • sxnR1
 563 - 997 (+) putative MarR transcriptional regulator
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    • UPN68078.1
    • sxnX1
    		 1088 - 2818 (+) putative carboxylase
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      • UPN68079.1
      • sxnO1
      		 2845 - 4296 (+) putative FAD-dependent monooxygenase
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        • UPN68080.1
        • sxnA1
        		 4313 - 4639 (+) cyclase
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          • UPN68081.1
          • sxnA2
          		 4636 - 5907 (+) ketoacyl synthase
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            • UPN68082.1
            • sxnA3
            		 5904 - 7118 (+) chain length factor
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              • UPN68083.1
              • sxnA4
              		 7141 - 7404 (+) acyl carrier protein
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                • UPN68084.1
                • sxnA5
                		 7420 - 8202 (+) reductase
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                  • UPN68085.1
                  • sxnA6
                  		 8243 - 9187 (+) cyclase
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                    • UPN68086.1
                    • sxnO2
                    		 9192 - 11111 (+) putative SDR family oxidoreductase
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                      • UPN68087.1
                      • sxnX2
                      		 11126 - 12697 (+) putative decarboxylase beta subunit
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                        • UPN68088.1
                        • sxnX3
                        		 12694 - 12813 (+) hypothetical protein
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                          • UPN68089.1
                          • sxnX4
                          		 12810 - 13016 (+) putative decarboxylase epsilon subunit
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                            • UPN68090.1
                            • sxnO3
                            		 13032 - 14015 (+) putative LLM class flavin-dependent oxidoreductase
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                              • UPN68091.1
                              • sxnT1
                              		 14008 - 15189 (+) putative MFS transporter
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                                • UPN68092.1
                                • sxnO4
                                		 15186 - 15770 (+) putative NADH-dependent oxidoreductase
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                                  • UPN68093.1
                                  • sxnR2
                                  		 15780 - 17171 (-) putative LuxR transcriptional regulator
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                                    • UPN68094.1
                                    • sxnR3
                                    		 17258 - 18463 (-) putative LuxR transcriptional regulator
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                                      • UPN68095.1
                                      • sxnO5
                                      		 18612 - 19397 (-) putative SDR family oxidoreductase
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                                        • UPN68096.1
                                        • sxnT2
                                        		 19580 - 20083 (+) putative nuclear transport factor 2 family protein
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                                          • UPN68097.1
                                          • sxnR4
                                          		 20097 - 21386 (-) putative LuxR transcriptional regulator
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                                            • UPN68098.1
                                            • sxnR5
                                            		 21796 - 22242 (+) putative Rrf2 family transcriptional regulator
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                                              • UPN68099.1
                                              • sxnT3
                                              		 22334 - 23785 (+) putative MFS transporter
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                                                • UPN68100.1
                                                • sxnM1
                                                		 23821 - 24591 (+) putative methyltransferase
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                                                  • UPN68101.1
                                                  • sxnR6
                                                  		 24784 - 26178 (+) putative LuxR transcriptional regulator
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                                                    • UPN68102.1
                                                    • sxnO6
                                                    		 26312 - 27151 (+) putative SDR family oxidoreductase
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                                                      • UPN68103.1
                                                      • sxnO7
                                                      		 27183 - 28379 (+) putative cytochrome P450
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                                                        • UPN68104.1
                                                        • sxnO8
                                                        		 28459 - 29247 (+) putative SDR family oxidoreductase
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                                                          • UPN68105.1
                                                          		 29461 - 30681 (+) putative vanadium-dependent haloperoxidase
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                                                            Biosynthesis information
                                                            Annotation changelog

                                                            Entry version: 1

                                                            Date
                                                            Changes
                                                            Submitters
                                                            Reviewers
                                                            2022-09-15
                                                            Entry added
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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