LOCUS       BGC0002678             25254 bp    DNA     linear   BCT 22-OCT-2015
DEFINITION  Burkholderia cepacia ATCC 25416 chromosome 2, complete sequence.
ACCESSION   BGC0002678
VERSION     BGC0002678
KEYWORDS    .
SOURCE      Burkholderia cepacia ATCC 25416
  ORGANISM  Burkholderia cepacia ATCC 25416
            Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
            Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
COMMENT     Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: http://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 18:12:12
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..1452)
                     /EC_number="5.4.4.2"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1018:isochorismate synthase (Score: 372.4; E-value:
                     6.6e-113)"
                     /gene_kind="biosynthetic-additional"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_011354275.1"
                     /locus_tag="APZ15_27885"
                     /note="involved in the conversion of chorismate to
                     salicylate; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /product="salicylate biosynthesis isochorismate synthase"
                     /protein_id="ALK21564.1"
                     /transl_table=11
                     /translation="MNAGLPLLHDTFARAARRAADTGTPTLASVSVPVRPLDFFDLIAA
                     WDDGATPWFFHEAGDASVTLFGWDSALELTATGDTRFAQIDARWRTLVRDAVTAGPQPP
                     RAVGGFRFDPRGARSAHWAPFPDASMTVATLLIVREGDAHWAVCQHVVAAHDDPAALAH
                     ACLARIESLGTLAAARDDAAPHLLHTQALQASEWQHEVRRAVDAIHGGAFGKVVLARDV
                     LEQYARPIAIAPLLRRLRTRDAHAHLFAVRREGACFVGATPERLARVAAGDVRTHALAG
                     TIRRGTTPDDDRALGAALMASAKERLEHALVVDAIRAALTPLSRALDVPGEPSLHRLPR
                     LQHLSTPIRATLKADATLLQVIAALHPTPAVAGHPRDAALDHIRAHEGFDRGWYAAPVG
                     WIDAHGNGDFIVALRSALVDGGACRLFAGCGIVADSEPVNEYQETELKLSGMQAAIRVR
                     DVEAGVEAAPDAHDPARVSASSTVE"
     protocluster    1..25254
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[5455:15345]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5456..15345
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     protocluster    1..25254
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[1448:15345]"
                     /cutoff="30000"
                     /detection_rule="(VibH_like or Cy_tandem or
                     (cds(Condensation and AMP-binding) and ((IBH_Asp and not
                     SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or
                     CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD
                     and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox
                     and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))"
                     /neighbourhood="20000"
                     /product="NRP-metallophore"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      1449..15345
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="30000"
                     /detection_rule="(VibH_like or Cy_tandem or
                     (cds(Condensation and AMP-binding) and ((IBH_Asp and not
                     SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or
                     CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD
                     and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox
                     and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))"
                     /neighbourhood="20000"
                     /product="NRP-metallophore"
                     /protocluster_number="2"
     cand_cluster    1..25254
                     /SMILES="NC(CS)C(=O)NC(CS)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /detection_rules="(VibH_like or Cy_tandem or
                     (cds(Condensation and AMP-binding) and ((IBH_Asp and not
                     SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or
                     CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD
                     and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox
                     and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))"
                     /kind="chemical_hybrid"
                     /product="NRPS"
                     /product="NRP-metallophore"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     subregion       1..25254
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002678"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..25254
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /product="NRP-metallophore"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /rules="(VibH_like or Cy_tandem or (cds(Condensation and
                     AMP-binding) and ((IBH_Asp and not SBH_Asp) or IBH_His or
                     TBH_Asp or CyanoBH_Asp1 or CyanoBH_Asp2 or IPL or SalSyn or
                     (EntA and EntC) or (GrbD and GrbE) or (FbnL and FbnM) or
                     PvdO or PvdP or (Orn_monoox and not (KtzT or MetRS-like))
                     or Lys_monoox or VbsL)))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(1..1452)
                     /locus_tag="APZ15_27885"
     gene            complement(1449..1754)
                     /locus_tag="APZ15_27890"
     CDS             complement(1449..1754)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: IPL"
                     /gene_kind="biosynthetic"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_011354276.1"
                     /locus_tag="APZ15_27890"
                     /note="catalyzes the second reaction in the pyochelin
                     biosynthetic pathway, the conversion of isochorismate to
                     salicylate and pyruvate; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="isochorismate-pyruvate lyase"
                     /protein_id="ALK21565.1"
                     /sec_met_domain="IPL (E-value: 7.3e-49, bitscore: 154.2,
                     seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTPDACTGLPDIREAIDRLDADIIDALGRRMQYVKAASRFKPDE
                     ASIAAPERVAAMLPDRRRWAEQAGLDGDYVETLFAGLIAWYIAQQTQHWRRQRGLA"
     gene            complement(1751..2524)
                     /locus_tag="APZ15_27895"
     CDS             complement(1751..2524)
                     /NRPS_PKS="Domain: Thioesterase (22-244). E-value: 8.5e-53.
                     Score: 171.9. Matches aSDomain:
                     nrpspksdomains_APZ15_27895_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004:thioesterase (Score: 246.9; E-value: 2.4e-75)"
                     /gene_kind="biosynthetic-additional"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_012339595.1"
                     /locus_tag="APZ15_27895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="enantio-pyochelin biosynthetic protein PchC"
                     /protein_id="ALK21566.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 5.7e-10, bitscore:
                     30.0, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSARPTGSNWIRELRLSPCPRAQLVCFPHAGGTANFFRNWSRALP
                     WDVDLLALQYPGREERFGEPCLTTIDALAGPAADALQRYAHAPLVLFGHSLGAALAYEV
                     AARLEARGAAPLYLAVSALPPPHRQRLSDLHLQSDDALVADVARLSGEHAALLADPEMR
                     AIYLPMIRHDYRAIETYRRDRPPRLDTPLGVMLPLADSELDDDEARAWQDVASRPIRIE
                     TFSGDHFYLRHQYPALIAHLVERIDQSLRYGKEYT"
     aSDomain        complement(1793..2458)
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_APZ15_27895_Thioesterase.1"
                     /evalue="8.50E-53"
                     /label="APZ15_27895_Thioesterase.1"
                     /locus_tag="APZ15_27895"
                     /protein_end="244"
                     /protein_start="22"
                     /score="171.9"
                     /tool="antismash"
                     /translation="QLVCFPHAGGTANFFRNWSRALPWDVDLLALQYPGREERFGEPCL
                     TTIDALAGPAADALQRYAHAPLVLFGHSLGAALAYEVAARLEARGAAPLYLAVSALPPP
                     HRQRLSDLHLQSDDALVADVARLSGEHAALLADPEMRAIYLPMIRHDYRAIETYRRDRP
                     PRLDTPLGVMLPLADSELDDDEARAWQDVASRPIRIETFSGDHFYLRHQYPALIAHLVE
                     "
     CDS_motif       complement(2201..2272)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APZ15_27895_0001"
                     /evalue="4.70E-09"
                     /label="NRPS-te1"
                     /locus_tag="APZ15_27895"
                     /protein_end="108"
                     /protein_start="84"
                     /score="28.7"
                     /tool="antismash"
                     /translation="AHAPLVLFGHSLGAALAYEVAARL"
     gene            complement(2521..4173)
                     /locus_tag="APZ15_27900"
     CDS             complement(2521..4173)
                     /NRPS_PKS="Domain: AMP-binding (42-447). E-value: 2.5e-83.
                     Score: 271.8. Matches aSDomain:
                     nrpspksdomains_APZ15_27900_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     468.9; E-value: 2.6e-142)"
                     /gene_kind="biosynthetic-additional"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_011354278.1"
                     /locus_tag="APZ15_27900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="2,3-dihydroxybenzoate-AMP ligase"
                     /protein_id="ALK21567.1"
                     /sec_met_domain="AMP-binding (E-value: 9.3e-91, bitscore:
                     294.2, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHSSLPSVAPAIPADAPDWPDDFAHRYRDAGYWQDTTFFEALDAQ
                     AQRAPDALAVVDGTCRLGYRDLLARIRQLAGGLARLGLARGDAVVVHLPNGARFIETCF
                     ALFQLGVRPVLALPAQRHYEIGAFCRFAGARAYLCAAHLGEFDCRPLAAALQADCPTLE
                     HVVMDGDDHAFTPFDALYDAPPLRECAARADDIACFQLSGGTTGTPKLIPRRHREYLYN
                     VRACSVASGFDAGTVYLAALPMAHNFTLCCPGTIGALLAGGRVVATGRPEPEQSFALIA
                     QERVTHTALVPPLALLWLDEQPQRRADLSSLRVLQVGGARLMDHAAARVTPVLGCRLQQ
                     VFGMAEGLICCTRLDDSPERIAHTQGRPVSDGDEVRIVDDAGEPVAPGEIGELQVRGPY
                     TIRGYYRLAEHNAAAFTADGFYRSGDRVRRTADGDLVVEGRDKDQINRGGEKVSAEEVE
                     NLLLAHPQVHDAAVVAMPDPLLGERTCAFVVARAPAPSRLVLKRYLRDCGLAAFKIPDR
                     IEFMPRFPETGIGKTSKKSLRDLLRRQLQAAAA"
     aSDomain        complement(2833..4047)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_APZ15_27900_AMP-binding.1"
                     /evalue="2.50E-83"
                     /label="APZ15_27900_AMP-binding.1"
                     /locus_tag="APZ15_27900"
                     /protein_end="447"
                     /protein_start="42"
                     /score="271.8"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="DAQAQRAPDALAVVDGTCRLGYRDLLARIRQLAGGLARLGLARGD
                     AVVVHLPNGARFIETCFALFQLGVRPVLALPAQRHYEIGAFCRFAGARAYLCAAHLGEF
                     DCRPLAAALQADCPTLEHVVMDGDDHAFTPFDALYDAPPLRECAARADDIACFQLSGGT
                     TGTPKLIPRRHREYLYNVRACSVASGFDAGTVYLAALPMAHNFTLCCPGTIGALLAGGR
                     VVATGRPEPEQSFALIAQERVTHTALVPPLALLWLDEQPQRRADLSSLRVLQVGGARLM
                     DHAAARVTPVLGCRLQQVFGMAEGLICCTRLDDSPERIAHTQGRPVSDGDEVRIVDDAG
                     EPVAPGEIGELQVRGPYTIRGYYRLAEHNAAAFTADGFYRSGDRVRRTADGDLVVEGRD
                     KDQINR"
     CDS_motif       complement(2929..3015)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APZ15_27900_0002"
                     /evalue="1.20E-05"
                     /label="NRPS-A_a6"
                     /locus_tag="APZ15_27900"
                     /protein_end="415"
                     /protein_start="386"
                     /score="17.7"
                     /tool="antismash"
                     /translation="PGEIGELQVRGPYTIRGYYRLAEHNAAAF"
     CDS_motif       complement(3367..3417)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APZ15_27900_0001"
                     /evalue="2.30E+00"
                     /label="NRPS-A_a6"
                     /locus_tag="APZ15_27900"
                     /protein_end="269"
                     /protein_start="252"
                     /score="0.9"
                     /tool="antismash"
                     /translation="PGTIGALLAGGRVVATG"
     gene            4391..5332
                     /locus_tag="APZ15_27905"
     CDS             4391..5332
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287:AraC family
                     transcriptional regulator (Score: 76.1; E-value: 4.3e-23)"
                     /gene_kind="regulatory"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_011354279.1"
                     /locus_tag="APZ15_27905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AraC family transcriptional regulator"
                     /protein_id="ALK21568.1"
                     /transl_table=11
                     /translation="MSSTSFASSRRHPPVLVPGNHPGVVHIDAGMKLMSGTLCSDSRDW
                     YEEPLEKGLKLVLVQSGQLRCRVPGQPEQCIKGPGLCVIANDGEFTTHQIYDRDVPLRY
                     TIVQLGLDALDRNLSLLPEKMLAPTGGDPRIVSCPASKALQALAVQIATCPFEGAVREY
                     YLKAKAFELTALSAQLLATQRQFAPADVRVTSSDVERVYAASDILTRELQQPPTLDALA
                     GRVGMNSRKLTAGFRKVFGTSVYAYLQEYRLRTAHAMLCAEDANVSTVAYRVGYSPAHF
                     SIAFRKRYGISPSDIRASSNAIDDAELESAAI"
     gene            5456..9874
                     /locus_tag="APZ15_27910"
     CDS             5456..9874
                     /NRPS_PKS="Domain: PP-binding (25-93). E-value: 2.1e-10.
                     Score: 32.9. Matches aSDomain:
                     nrpspksdomains_APZ15_27910_PP-binding.1"
                     /NRPS_PKS="Domain: Heterocyclization (119-416). E-value:
                     7.5e-98. Score: 319.4. Matches aSDomain:
                     nrpspksdomains_APZ15_27910_Heterocyclization.1"
                     /NRPS_PKS="Domain: AMP-binding (577-968). E-value: 1.2e-94.
                     Score: 309.1. Matches aSDomain:
                     nrpspksdomains_APZ15_27910_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1378-1446). E-value: 2.6e-17.
                     Score: 54.7. Matches aSDomain:
                     nrpspksdomains_APZ15_27910_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_011354280.1"
                     /locus_tag="APZ15_27910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="ALK21569.1"
                     /sec_met_domain="Condensation (E-value: 1.5e-40, bitscore:
                     128.9, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.7e-102, bitscore:
                     332.9, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 5.5e-16, bitscore:
                     48.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQTAVDSTIDHSDPSCFSPIAFRSQLVAMIAALLDEPVDEIASL
                     DDDEDLLSCGLDSIRLMYLQTRVNRLGYALTFDALARTPTLGAWAELLANAPRGASAAP
                     DVEAAEAAEAVDVDVHAPFDLSAVQQAYWLGRGDGEVLGNVSCHAFLEFRSRAIDPVRL
                     DAACRLVRERHPMLRARFAGGRQQIVAAPEAPVFAHADWRDRTPAEAETEWVSLRAFRS
                     HECLDVEHAQVFMMGLAQMPGGEDRVWLSVDLLAADVDSVRLLMQEIGAAYAEPSALPD
                     APSTWFPTWLARRAADTRDARAAARDAWQARLATLPEGPALPLARAPETIRAPRFSRVT
                     HTLSTAELTRLQARAAQHGVTLSSVFGAAFAAVLARWSGRQAFLLNVPLFDRHGDAPDL
                     GRVIADFTTLLLVECDMRADASAADTVRAFQQRLHGAIAQAAYPALDVLRDARRQGAPR
                     AAPVVFSCNLGDAPFVPDAFARVFGDLHDMISQTPQVWLDHQLYRVPDGALLAWDSVDG
                     LFPDGMVDAMFGAYVALVQALCDRDWRLPIAVELPSAQRRVRDALNAVPAPARPRTLHA
                     DFFASAAREPAAVALRCAERVVTRGELAAQALAIAGGLRAAGIGHGDAVEISLPRGPEQ
                     VAAVFGVLAAGACYVPLDIAQPAARKALIERAAGVKAAIGDTAHADAPLPRFDVASLMK
                     HAPLAAPLAVAPQATAYVIYTSGSTGVPKGVEMTHAAALNTIDAIDALLGVRAQDRLLA
                     VSALDFDLSVYDLFGVLGAGAELVLPTQDDARDAARWIDLIAQHRVTLWNSAPALLEMA
                     LAVPAAADACRSVRAALLSGDWIALDLPARLRERCGDACAFHALGGATEAGIWSNVQTV
                     RDVPPHWRSIPYGRPLPGQAYRVVDTDGRDVPDYVPGELLIGGDSLARGYRNDPELTAQ
                     RFVQHASGRWYRTGDRGRYWPDGTLEFLGREDRQVKVRGHRIELGEIEAALAAHPQIDG
                     ACASVVNGEVARIVAAFVPADCGAACVADAAPSSLAEADLADTVEAEAAVARAVADRLL
                     DGGAGLPPSLRAHRHAKSDASISIDGALDRLDWYATDLDDLTASLRALAADPDTAAQRV
                     PLDPCVAPLAFATRLPDGARALREFAGALEAQAAARTGLLRVAVVDARAGQWFEAGLGV
                     LDDPRFDVTLFDVSPGLLHTAQARFTLTRPALQAMQDGLLPARHLGEFDCVISFAAAHL
                     RDDPRDTFRIAAALLAQDGRLLFADVLRDSPLRELVASVAGDASLPRPFTPDAIAAAAH
                     ACGFALDSRSWRSNAFACIDARRTGEPAAQAALADWLRDRLPDAMRPDALWCIARWPLN
                     ANGKIDRRAVGEALARALGDAPAAHDAFVPADERQATLLACWEHALGRPANARDATFFA
                     LGGDSLLATRLLAQLRERLGVRVGMAAFYRQPTLAGLAAQLDEAAPAAPALQASQADGD
                     TPVATIEEGVL"
     aSDomain        5531..5734
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_APZ15_27910_PP-binding.1"
                     /evalue="2.10E-10"
                     /label="APZ15_27910_PP-binding.1"
                     /locus_tag="APZ15_27910"
                     /protein_end="93"
                     /protein_start="25"
                     /score="32.9"
                     /tool="antismash"
                     /translation="QLVAMIAALLDEPVDEIASLDDDEDLLSCGLDSIRLMYLQTRVNR
                     LGYALTFDALARTPTLGAWAELL"
     aSDomain        5813..6703
                     /aSDomain="Heterocyclization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_APZ15_27910_Heterocyclization.1"
                     /evalue="7.50E-98"
                     /label="APZ15_27910_Heterocyclization.1"
                     /locus_tag="APZ15_27910"
                     /protein_end="416"
                     /protein_start="119"
                     /score="319.4"
                     /tool="antismash"
                     /translation="HAPFDLSAVQQAYWLGRGDGEVLGNVSCHAFLEFRSRAIDPVRLD
                     AACRLVRERHPMLRARFAGGRQQIVAAPEAPVFAHADWRDRTPAEAETEWVSLRAFRSH
                     ECLDVEHAQVFMMGLAQMPGGEDRVWLSVDLLAADVDSVRLLMQEIGAAYAEPSALPDA
                     PSTWFPTWLARRAADTRDARAAARDAWQARLATLPEGPALPLARAPETIRAPRFSRVTH
                     TLSTAELTRLQARAAQHGVTLSSVFGAAFAAVLARWSGRQAFLLNVPLFDRHGDAPDLG
                     RVIADFTTLLLVECDM"
     aSModule        5813..9793
                     /complete
                     /domains="nrpspksdomains_APZ15_27910_Heterocyclization.1"
                     /domains="nrpspksdomains_APZ15_27910_AMP-binding.1"
                     /domains="nrpspksdomains_APZ15_27910_PCP.1"
                     /locus_tags="APZ15_27910"
                     /monomer_pairings="Cys -> Cys"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       5837..5863
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APZ15_27910_0001"
                     /evalue="8.10E-03"
                     /label="Cy1"
                     /locus_tag="APZ15_27910"
                     /protein_end="136"
                     /protein_start="127"
                     /score="9.1"
                     /tool="antismash"
                     /translation="VQQAYWLGR"
     CDS_motif       5924..6001
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APZ15_27910_0002"
                     /evalue="1.60E-05"
                     /label="C2_LCL_024-062"
                     /locus_tag="APZ15_27910"
                     /protein_end="182"
                     /protein_start="156"
                     /score="17.3"
                     /tool="antismash"
                     /translation="AIDPVRLDAACRLVRERHPMLRARFA"
     CDS_motif       6194..6238
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APZ15_27910_0003"
                     /evalue="5.50E-03"
                     /label="Cy3"
                     /locus_tag="APZ15_27910"
                     /protein_end="261"
                     /protein_start="246"
                     /score="10.2"
                     /tool="antismash"
                     /translation="RVWLSVDLLAADVDS"
     CDS_motif       6530..6589
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APZ15_27910_0004"
                     /evalue="1.80E-07"
                     /label="Cy4"
                     /locus_tag="APZ15_27910"
                     /protein_end="378"
                     /protein_start="358"
                     /score="23.9"
                     /tool="antismash"
                     /translation="GVTLSSVFGAAFAAVLARWS"
     CDS_motif       6602..6634
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APZ15_27910_0005"
                     /evalue="1.80E-03"
                     /label="afterCy4"
                     /locus_tag="APZ15_27910"
                     /protein_end="393"
                     /protein_start="382"
                     /score="11.1"
                     /tool="antismash"
                     /translation="FLLNVPLFDRH"
     CDS_motif       6644..6700
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APZ15_27910_0006"
                     /evalue="2.10E-07"
                     /label="Cy5"
                     /locus_tag="APZ15_27910"
                     /protein_end="415"
                     /protein_start="396"
                     /score="23.2"
                     /tool="antismash"
                     /translation="PDLGRVIADFTTLLLVECD"
     CDS_motif       6920..6994
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APZ15_27910_0007"
                     /evalue="2.90E-08"
                     /label="Cy7"
                     /locus_tag="APZ15_27910"
                     /protein_end="513"
                     /protein_start="488"
                     /score="26.3"
                     /tool="antismash"
                     /translation="ISQTPQVWLDHQLYRVPDGALLAWD"
     CDS_motif       7010..7039
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APZ15_27910_0008"
                     /evalue="7.60E-03"
                     /label="afterCy7"
                     /locus_tag="APZ15_27910"
                     /protein_end="528"
                     /protein_start="518"
                     /score="9.7"
                     /tool="antismash"
                     /translation="FPDGMVDAMF"
     aSDomain        7187..8359
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_APZ15_27910_AMP-binding.1"
                     /evalue="1.20E-94"
                     /label="APZ15_27910_AMP-binding.1"
                     /locus_tag="APZ15_27910"
                     /protein_end="968"
                     /protein_start="577"
                     /score="309.1"
                     /specificity="substrate consensus: Cys"
                     /tool="antismash"
                     /translation="FFASAAREPAAVALRCAERVVTRGELAAQALAIAGGLRAAGIGHG
                     DAVEISLPRGPEQVAAVFGVLAAGACYVPLDIAQPAARKALIERAAGVKAAIGDTAHAD
                     APLPRFDVASLMKHAPLAAPLAVAPQATAYVIYTSGSTGVPKGVEMTHAAALNTIDAID
                     ALLGVRAQDRLLAVSALDFDLSVYDLFGVLGAGAELVLPTQDDARDAARWIDLIAQHRV
                     TLWNSAPALLEMALAVPAAADACRSVRAALLSGDWIALDLPARLRERCGDACAFHALGG
                     ATEAGIWSNVQTVRDVPPHWRSIPYGRPLPGQAYRVVDTDGRDVPDYVPGELLIGGDSL
                     ARGYRNDPELTAQRFVQHASGRWYRTGDRGRYWPDGTLEFLGREDRQVKVR"
     CDS_motif       7373..7414
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APZ15_27910_0009"
                     /evalue="4.00E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="APZ15_27910"
                     /protein_end="653"
                     /protein_start="639"
                     /score="13.8"
                     /tool="antismash"
                     /translation="FGVLAAGACYVPLD"
     CDS_motif       7583..7642
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APZ15_27910_0010"
                     /evalue="1.00E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="APZ15_27910"
                     /protein_end="729"
                     /protein_start="709"
                     /score="30.3"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGVPKGVEMTH"
     CDS_motif       8162..8251
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APZ15_27910_0011"
                     /evalue="1.80E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="APZ15_27910"
                     /protein_end="932"
                     /protein_start="902"
                     /score="49.0"
                     /tool="antismash"
                     /translation="PDYVPGELLIGGDSLARGYRNDPELTAQRF"
     CDS_motif       8324..8389
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APZ15_27910_0012"
                     /evalue="8.60E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="APZ15_27910"
                     /protein_end="978"
                     /protein_start="956"
                     /score="37.0"
                     /tool="antismash"
                     /translation="FLGREDRQVKVRGHRIELGEIE"
     aSDomain        9590..9793
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_APZ15_27910_PCP.1"
                     /evalue="2.60E-17"
                     /label="APZ15_27910_PCP.1"
                     /locus_tag="APZ15_27910"
                     /protein_end="1446"
                     /protein_start="1378"
                     /score="54.7"
                     /tool="antismash"
                     /translation="ATLLACWEHALGRPANARDATFFALGGDSLLATRLLAQLRERLGV
                     RVGMAAFYRQPTLAGLAAQLDEA"
     gene            9871..15345
                     /locus_tag="APZ15_27915"
     CDS             9871..15345
                     /NRPS_PKS="Domain: Heterocyclization (64-364). E-value:
                     1.4e-114. Score: 374.3. Matches aSDomain:
                     nrpspksdomains_APZ15_27915_Heterocyclization.1"
                     /NRPS_PKS="Domain: AMP-binding (523-920). E-value: 2.8e-95.
                     Score: 311.2. Matches aSDomain:
                     nrpspksdomains_APZ15_27915_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1422-1494). E-value: 3.6e-11.
                     Score: 35.0. Matches aSDomain:
                     nrpspksdomains_APZ15_27915_PCP.1"
                     /NRPS_PKS="Domain: Thioesterase (1545-1812). E-value:
                     2.3e-12. Score: 39.6. Matches aSDomain:
                     nrpspksdomains_APZ15_27915_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_011354281.1"
                     /locus_tag="APZ15_27915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="ALK21570.1"
                     /sec_met_domain="Condensation (E-value: 1.2e-35, bitscore:
                     112.9, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.3e-104, bitscore:
                     339.0, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 9.5e-10, bitscore:
                     28.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSFDDVLDLCRERRIELWCDDGGQLRYRAPAGALDADLAARIKAE
                     RDAFVRFLQDGAWRCDPVRRHERFALTPVQAAYVLGRHESFEFGGNACHLYVEYGEPAN
                     LDCVRFEAAWNACVARHPMLRAIVEDNAWQRVLPDVPWQPLTVHDLRDADANAFDAHVK
                     RVRERLDHAVHALDRWPVLQPEVSLGPDGAVLHLSVDFTLIDYASLQLLLAEWRRRYDD
                     PQWQPEALDATFRDYVVNEAHAGTRAEHARDKAWWLARIDDLPPRPDLPVVPAMPSGAR
                     PRFTHRHARLDRAQWAALSGHASRFGLSAASVALAAFAEVVGRWSQSPAFCLNLTVLNR
                     PPVHPRIDAVLGDFTALSLLAVDVTHGRDFVERARTIGARMFDDLDHRAFTGVDVMREL
                     ARRRGKDAALMPVVFTSGIGSVGRLLGEHAARAEPPRYMISQTPQVWLDCQVTDQFGGL
                     EIGWDVRDDLFPDGMPAAMFDAYVALLGRLAADAAWWSRAGDIVLPSAAPAAGIHPDAD
                     THIAAGFAAQALRTPDAPVVIDAQGARTYRDVAQHAAALRSALEQAGVAAGDTVAVLMP
                     KCAHQLVAVLAIVQAGAAYVPVDSRQPALRQQAILRNARVRAVVSVQALEFEHDGCVRI
                     DVDAVPVDPQWPPRAARDIPGDALAYVIYTSGSTGEPKGVMLSHAAVCNTLADISARHE
                     VGDGDVVLGLAELSFDLSVYDFFGATARGACIVLPDPARGNDPSHWAALMARHRVTLWN
                     SVPAQGQMLIDYVEGEPALDVPGPRRVLWSGDWIPVTLPTRWWRRWPDSALFSLGGATE
                     ASIWSIEHPIRPADTQLASIPYGRALTGQTMEVLDALGRSCPPGVRGEIHIGGVGLATG
                     YANDPVRTAERFIRHGDGRRLYRTGDLGRVRADGSLEFLGRQDDQVKIRGYRIELAEID
                     AALTAHPLVGAAATIVLGDGTERRLASFVSLHGAEPPQQDDALHEIAAHVRTAFDAARW
                     PAHADVARSVARLEAACVASLAAWIVPAGALTEEQATDFATLCERLRVPAARQHLLRHW
                     LAMLDRHGVLHADAEGGWRRRPDAGHADAHACWDAFAQDASPDLWPAVLVDYFRDSAGC
                     IDVQVDGTVSPAGLMFPEGASHIADAMYSDGEHARALHDGMAQAVRAIVAREPQRPWRI
                     LEIGAGTAAATRAIVDALAPLVEAGVRIDYLFSDVSSYFLAAARERFAAYPWMRFERFD
                     MNAALDAQGIAPHSIDITISSGALNNARDTVALVAGLRALSAADAWWVIQELTTEHPEI
                     SISQGLMMETPHDARVESARLFVPRAQWLEWLQEAGGDRALGCVAPGTPLDALGYDILL
                     AHVKRGAARIAPDALLACVAERVPGYMVPSQLRVLDRLPVTANGKIDRRTLAGIADIRE
                     PEPAAARPAHAQAAADPLLARLIGLWEAVLDTRNVTPDQDFFAAGGDSLLIAQLVSRLR
                     GEEPLAHAHPFDRLLRWVLAQPTPAAFAQCLRDADARPSGSASPVAPAAPRSAHVSAVV
                     HAPAPRVRAGVRPITLAPGDGVPRVIVHEGLGTVHAYRPVMPALARLGPVLGFAVRDAQ
                     DYLDLPARHLNATLGRRYADALWRTGVREVDVLGYCSGGLVALEMAKSLVQLGVEVRTL
                     DIVSSYRIPYLIEDERLVLFNFAATLGLPLDALGFPETYVLADALADALKADPARLAPG
                     SLQAQLEIFGDRCEPLDTLRRRVLRAAAGLSMQDEVAHPLLDERERLYRLFMHSVQASH
                     WAGDAPYAGALRLFVPERCNPLIPQQRAALTEYWTAQALGGITSVDIPGGHFDCLNAAF
                     VDTRLKEAQ"
     aSDomain        10063..10962
                     /aSDomain="Heterocyclization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_APZ15_27915_Heterocyclization.1"
                     /evalue="1.40E-114"
                     /label="APZ15_27915_Heterocyclization.1"
                     /locus_tag="APZ15_27915"
                     /protein_end="364"
                     /protein_start="64"
                     /score="374.3"
                     /tool="antismash"
                     /translation="RHERFALTPVQAAYVLGRHESFEFGGNACHLYVEYGEPANLDCVR
                     FEAAWNACVARHPMLRAIVEDNAWQRVLPDVPWQPLTVHDLRDADANAFDAHVKRVRER
                     LDHAVHALDRWPVLQPEVSLGPDGAVLHLSVDFTLIDYASLQLLLAEWRRRYDDPQWQP
                     EALDATFRDYVVNEAHAGTRAEHARDKAWWLARIDDLPPRPDLPVVPAMPSGARPRFTH
                     RHARLDRAQWAALSGHASRFGLSAASVALAAFAEVVGRWSQSPAFCLNLTVLNRPPVHP
                     RIDAVLGDFTALSLLAVDV"
     aSModule        10063..15306
                     /complete
                     /domains="nrpspksdomains_APZ15_27915_Heterocyclization.1"
                     /domains="nrpspksdomains_APZ15_27915_AMP-binding.1"
                     /domains="nrpspksdomains_APZ15_27915_PCP.1"
                     /domains="nrpspksdomains_APZ15_27915_Thioesterase.1"
                     /final_module
                     /locus_tags="APZ15_27915"
                     /monomer_pairings="Cys -> Cys"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       10183..10248
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APZ15_27915_0001"
                     /evalue="7.20E-07"
                     /label="C2_DCL_024-062"
                     /locus_tag="APZ15_27915"
                     /protein_end="126"
                     /protein_start="104"
                     /score="21.5"
                     /tool="antismash"
                     /translation="LDCVRFEAAWNACVARHPMLRA"
     CDS_motif       10450..10494
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APZ15_27915_0002"
                     /evalue="1.10E-02"
                     /label="Cy3"
                     /locus_tag="APZ15_27915"
                     /protein_end="208"
                     /protein_start="193"
                     /score="9.3"
                     /tool="antismash"
                     /translation="VLHLSVDFTLIDYAS"
     CDS_motif       10789..10848
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APZ15_27915_0003"
                     /evalue="3.30E-06"
                     /label="Cy4"
                     /locus_tag="APZ15_27915"
                     /protein_end="326"
                     /protein_start="306"
                     /score="20.0"
                     /tool="antismash"
                     /translation="GLSAASVALAAFAEVVGRWS"
     CDS_motif       10861..10899
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APZ15_27915_0004"
                     /evalue="2.30E-04"
                     /label="afterCy4"
                     /locus_tag="APZ15_27915"
                     /protein_end="343"
                     /protein_start="330"
                     /score="13.8"
                     /tool="antismash"
                     /translation="FCLNLTVLNRPPV"
     CDS_motif       10900..10959
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APZ15_27915_0005"
                     /evalue="3.40E-08"
                     /label="Cy5"
                     /locus_tag="APZ15_27915"
                     /protein_end="363"
                     /protein_start="343"
                     /score="25.7"
                     /tool="antismash"
                     /translation="HPRIDAVLGDFTALSLLAVD"
     CDS_motif       11020..11067
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APZ15_27915_0006"
                     /evalue="8.80E-07"
                     /label="afterCy5"
                     /locus_tag="APZ15_27915"
                     /protein_end="399"
                     /protein_start="383"
                     /score="21.3"
                     /tool="antismash"
                     /translation="DLDHRAFTGVDVMREL"
     CDS_motif       11185..11226
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APZ15_27915_0007"
                     /evalue="1.50E-06"
                     /label="Cy7"
                     /locus_tag="APZ15_27915"
                     /protein_end="452"
                     /protein_start="438"
                     /score="21.1"
                     /tool="antismash"
                     /translation="ISQTPQVWLDCQVT"
     aSDomain        11440..12630
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_APZ15_27915_AMP-binding.1"
                     /evalue="2.80E-95"
                     /label="APZ15_27915_AMP-binding.1"
                     /locus_tag="APZ15_27915"
                     /protein_end="920"
                     /protein_start="523"
                     /score="311.2"
                     /specificity="substrate consensus: Cys"
                     /tool="antismash"
                     /translation="FAAQALRTPDAPVVIDAQGARTYRDVAQHAAALRSALEQAGVAAG
                     DTVAVLMPKCAHQLVAVLAIVQAGAAYVPVDSRQPALRQQAILRNARVRAVVSVQALEF
                     EHDGCVRIDVDAVPVDPQWPPRAARDIPGDALAYVIYTSGSTGEPKGVMLSHAAVCNTL
                     ADISARHEVGDGDVVLGLAELSFDLSVYDFFGATARGACIVLPDPARGNDPSHWAALMA
                     RHRVTLWNSVPAQGQMLIDYVEGEPALDVPGPRRVLWSGDWIPVTLPTRWWRRWPDSAL
                     FSLGGATEASIWSIEHPIRPADTQLASIPYGRALTGQTMEVLDALGRSCPPGVRGEIHI
                     GGVGLATGYANDPVRTAERFIRHGDGRRLYRTGDLGRVRADGSLEFLGRQDDQVKIR"
     CDS_motif       11626..11667
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APZ15_27915_0008"
                     /evalue="3.80E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="APZ15_27915"
                     /protein_end="599"
                     /protein_start="585"
                     /score="13.9"
                     /tool="antismash"
                     /translation="LAIVQAGAAYVPVD"
     CDS_motif       11848..11907
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APZ15_27915_0009"
                     /evalue="5.00E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="APZ15_27915"
                     /protein_end="679"
                     /protein_start="659"
                     /score="34.3"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGEPKGVMLSH"
     CDS_motif       12430..12519
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APZ15_27915_0010"
                     /evalue="1.60E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="APZ15_27915"
                     /protein_end="883"
                     /protein_start="853"
                     /score="42.8"
                     /tool="antismash"
                     /translation="PPGVRGEIHIGGVGLATGYANDPVRTAERF"
     CDS_motif       12595..12657
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APZ15_27915_0011"
                     /evalue="1.80E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="APZ15_27915"
                     /protein_end="929"
                     /protein_start="908"
                     /score="36.0"
                     /tool="antismash"
                     /translation="FLGRQDDQVKIRGYRIELAEI"
     CDS_motif       13444..13479
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APZ15_27915_0012"
                     /evalue="1.40E+01"
                     /label="Cy3"
                     /locus_tag="APZ15_27915"
                     /protein_end="1203"
                     /protein_start="1191"
                     /score="-0.2"
                     /tool="antismash"
                     /translation="VRIDYLFSDVSS"
     aSDomain        14137..14352
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_APZ15_27915_PCP.1"
                     /evalue="3.60E-11"
                     /label="APZ15_27915_PCP.1"
                     /locus_tag="APZ15_27915"
                     /protein_end="1494"
                     /protein_start="1422"
                     /score="35.0"
                     /tool="antismash"
                     /translation="RLIGLWEAVLDTRNVTPDQDFFAAGGDSLLIAQLVSRLRGEEPLA
                     HAHPFDRLLRWVLAQPTPAAFAQCLRD"
     aSDomain        14506..15306
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_APZ15_27915_Thioesterase.1"
                     /evalue="2.30E-12"
                     /label="APZ15_27915_Thioesterase.1"
                     /locus_tag="APZ15_27915"
                     /protein_end="1812"
                     /protein_start="1545"
                     /score="39.6"
                     /tool="antismash"
                     /translation="IVHEGLGTVHAYRPVMPALARLGPVLGFAVRDAQDYLDLPARHLN
                     ATLGRRYADALWRTGVREVDVLGYCSGGLVALEMAKSLVQLGVEVRTLDIVSSYRIPYL
                     IEDERLVLFNFAATLGLPLDALGFPETYVLADALADALKADPARLAPGSLQAQLEIFGD
                     RCEPLDTLRRRVLRAAAGLSMQDEVAHPLLDERERLYRLFMHSVQASHWAGDAPYAGAL
                     RLFVPERCNPLIPQQRAALTEYWTAQALGGITSVDIPGGHFDCLN"
     CDS_motif       14635..14661
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APZ15_27915_0013"
                     /evalue="6.60E+01"
                     /label="afterCy4"
                     /locus_tag="APZ15_27915"
                     /protein_end="1597"
                     /protein_start="1588"
                     /score="-2.5"
                     /tool="antismash"
                     /translation="LNATLGRRY"
     CDS_motif       14701..14754
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APZ15_27915_0014"
                     /evalue="6.60E-06"
                     /label="NRPS-te1"
                     /locus_tag="APZ15_27915"
                     /protein_end="1628"
                     /protein_start="1610"
                     /score="18.7"
                     /tool="antismash"
                     /translation="VLGYCSGGLVALEMAKSL"
     gene            15342..16394
                     /locus_tag="APZ15_27920"
     CDS             15342..16394
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1099:hypothetical
                     protein (Score: 354; E-value: 1.6e-107)"
                     /gene_kind="other"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_011547174.1"
                     /locus_tag="APZ15_27920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="oxidoreductase"
                     /protein_id="ALK21571.1"
                     /transl_table=11
                     /translation="MKAHPLPVVVAGSRFGQFYAAGLAASGTYRVAGILGQGSARTAAL
                     AARVGAPVFDRPEALPDDVRAACVAVGGAARGADGAALACRLLERGIDVVIEHPLLPDE
                     WDRVLRTASRHGRRCLLNSFYPNLPVVSRFIAVARRLRETSAPVHADVVCSVQASYAAL
                     DVLAAALQGVGPWSVEPVGPALSSMRECAMVLAETPVSLRVHNEMAAADDGRMSMLFSI
                     TLTTDAGTWTLASPHGPLWWAPALREPATDDDGLFPIFGDAAGDDMPSIQICDDARDTW
                     GAIHARSWPQAAVRAVDRLVSGEGLHACNQRSIDVTRVWQQLTMQLGFPEQPPGDACAA
                     TLGMLLERAA"
     gene            16391..18112
                     /locus_tag="APZ15_27925"
     CDS             16391..18112
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 236.2; E-value:
                     1.2e-71)"
                     /gene_kind="transport"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_012339601.1"
                     /locus_tag="APZ15_27925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="multidrug ABC transporter permease"
                     /protein_id="ALK21572.1"
                     /transl_table=11
                     /translation="MKGPLLSMLRPFAAPLAAAVVLQALAGVASLVPWLALGRIADAWR
                     ATAQLDATARGWLVAAVVAGVCWLGGQTVALHLTHRVDADLADRLRRRLADHLQRLPLG
                     WFARAGSDRVARHVDQDVRALHQLVAHAPADVTQLVVVPCAALACLLYLNPGLLAFALV
                     PLVAGAALFRWMRSARFVPAVAARNAALEQLMGDYAQLAQNPALVRQYPGAGIEAAVLA
                     STGRFDQAFSAWVGRVGGPGACTQVLLGTPFLLAWVVFGATWLTAGRLPVGELCAFALL
                     IWAVAAPVRALGHGADALREARAAAARLDALLAQPGLPEPADGAAQVPRDASIELRGVS
                     VDIDGTPILRDIDAAVAAGTTTAIVGPSGAGKSTLLMLLARFMDPDRGTVRLGGADLRL
                     LAPDTRREQVAMVFQQAAALDVSIAANIALYRPDADHDAIRAAARAACLDERIDALPGG
                     YGCVCGRDVRLSGGELQRLAIARALLSTAPLLLLDEPASALDPQTARALRNALRGDART
                     RVIVSHDLDAIRQADQILVMDRGRIVERGTHAALLAACGLYARLWRERGAADGEAA"
     gene            18112..19875
                     /locus_tag="APZ15_27930"
     CDS             18112..19875
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 255.7; E-value:
                     1.5e-77)"
                     /gene_kind="transport"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_011354284.1"
                     /locus_tag="APZ15_27930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyl transferase family 2"
                     /protein_id="ALK21573.1"
                     /transl_table=11
                     /translation="MVKSLKRLQCLPSGTRRALWRGVGWAVAAALLDGACGLLLVPLIR
                     AWFAGAQGAVLHWTIVLGALTLCHAFVLYVAQRGGYRAGGALAAGLVERLVRHLPRIAS
                     WQTVRDSHPAGLLRGPVMQAMGIPAHLLGPLIGAVVTPLAVVAGLAWIDWRIALCLAAA
                     AVLLFALLERGGTRTLAFEQARASGDRDMAVQLQTFAAHQGLLRFAGREGDARAALMHA
                     FDAQHRRTRALMRRSLPIELGFAGAVQGVFVAMLAGGAWAVSAGRLDAATAVAVLVLLV
                     RFIEPLAQLTQLDQALRGAWRALDTVLAVLHAPRFDSPDRGTPVHDASVDAVRVGYRSP
                     AGATLLDGVDLHCPAGGFVAIVGPTGAGKSTLLGLLARLDDPGAGRVLLGRADVRHLSE
                     ATLAATRNLVFQDNGLFRGSLAWNVRMGRPDATDAELRDALDAVGLLHDAERLPDGLES
                     DVGPGGQLLSGGQRQRACLARALLSRAPVLMFDEPTASLDESSARRVRDSLVALRGQRT
                     RIVVTHQPALAAAADTIVVLDAGRVRATGTHAQLVQADAWYATFARAGQLPDGLAPAET
                     IAEARPAESEH"
     gene            19989..22211
                     /locus_tag="APZ15_27935"
     CDS             19989..22211
                     /codon_start=1
                     /gene_functions="transport (smcogs)
                     SMCOG1051:TonB-dependent siderophore receptor (Score:
                     701.2; E-value: 2.7e-212)"
                     /gene_kind="transport"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_011354285.1"
                     /locus_tag="APZ15_27935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="ALK21574.1"
                     /transl_table=11
                     /translation="MRYEVLEPGRSMTKGARVARSGRGRWRPSLYLGLLIAAHPAAAFA
                     DAAPAAGAEVRKEETTAVKPAAGELKAISVTGSRGVADDPAVATVGKMPLALREIPQSV
                     SVTTRERIDQQNLYSLDEVMQQSAGVTVQPYVLLTTAYFVRGFKVDSFEFDGVPVVIGD
                     MASAPQDISVYERVEILRGANGLLHGSGNPAATVNLVRKRPQYQFSANASVSVGSWDRY
                     RAEADIGGPLNAAGTVRSRLVAAYEDRHFFYDHAKQDTRSIYGITEVDVTRDTLLTFGA
                     QYQTTRSVPDMSGVPMARDGSSLGLSRSTFLDTAWGHFDWDTTRAFASVEQKLGAGWKA
                     KVSGEYQSVRSDLKYAGSYGAIDPATGAGGALTGGAYRFSSYSRSIDANVQGPVHAFGL
                     THDLLFGVTYANSSSGQMSAQLLGNVAGMPVNVYRWNPSSMPEPGVGPYQQSQQNDVSQ
                     KGVYGLGRIKLAEPVTLVLGGRMSWWNQDSLGAHYNTGHQFTPYGGLIWDFARDWSWYA
                     SYAEVFQPQTKSMWGGGILTPVKGRTYETGVKGELAGGKLNVSLAAFRIDLDNNPQVDL
                     AHPCAGPNCYYVNGGSVRSQGFEFEANGRITPWWSVWASYTYDTMRYADNLANAGTFAP
                     LLNPRHLFRLWTNYDLPWQERRWSVGGGVQVQSNYSAQANGVTMSQGGYALASVRLGYR
                     YDKHWSAAVNVNNLFDRKYYLSLSQPGWNNRYGEPRNVMLTVRGQF"
     gene            22211..22474
                     /locus_tag="APZ15_27940"
     CDS             22211..22474
                     /codon_start=1
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_011354286.1"
                     /locus_tag="APZ15_27940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="ALK21575.1"
                     /transl_table=11
                     /translation="MAGGWGTRAALAIAGVLPGAVALAVTLARHYPADGLNRLYAAVLL
                     SLAAGVAALLWVLVAPGRRQAAWRACLWLAVLVPCAMFWGGR"
     gene            22476..23987
                     /locus_tag="APZ15_27945"
     CDS             22476..23987
                     /codon_start=1
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_006498816.1"
                     /locus_tag="APZ15_27945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="ALK21576.1"
                     /transl_table=11
                     /translation="MDASSRSRWRALHRGAGALFGVVLFVVLFSGTWSLATDSMQGWWR
                     APPVAVARPALPLDTLVARAAALGVPLRDARIVLPQPDDPAIRFCDARQACTLALDPAT
                     GERLADGGRAALLVTLHKTLFAGFPGRIFVSLWGIVLLVLIVAGLVVHHRRWPAAARIR
                     RGSGLRAALFDLHAWIGLWGSPWLVLFAFTGALSGLGALGTVSLAGVAYPGQPQRAFAE
                     LLGGPPPTAAGGAWQRAPDLEALLRRDAARTPDFRREAVVLHRWGDVNARVEIAGTTAG
                     LPSTALFERHLYRAVDGQWLADATSRGRGFWLRAFIAVQPLHFAQYGWVGAMGGVLRVL
                     HFLMGLAACALCATGLHLWIERRRAQHDRSANVLAAVAVGACGGLVLAGGVLLLAGRAL
                     PAGVHVDHVLAMLFWAVWGGALALAACVADRAAWLRTLMRAAGAAYGLAGATHCAIALL
                     GAGEPVYWPIDAALVAFGALLLRAARRPRLDAIRPARVPAGAEPF"
     gene            24010..25254
                     /locus_tag="APZ15_27950"
     CDS             24010..25254
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1131:major
                     facilitator transporter (Score: 446.9; E-value: 8e-136)"
                     /gene_kind="transport"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_012339606.1"
                     /locus_tag="APZ15_27950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="ALK22552.1"
                     /transl_table=11
                     /translation="MRDLLEHRRLVITITLLYLSQGIPIGIAMDAMPTLLRHDGAPLHA
                     LAFLPLVGLPWVVKFLWAPVVDNRWSPRIGRRRSWMLPMQTLVVLCLGSLAQIGMTVAT
                     AGWAVGLLAVASLASATQDIANDGMAAEHFSGDTLAKINAIQIAGVMIGFFGGGAGTLT
                     LIGLFGQRAAFLALAAVPLASLVCVLWVLPRDADRARAKPEHDASLVRFAKRPRSWSLL
                     SLALLSAMTAVSGFGLSKLFLNDAGWTLDAIGKLGMAGGIVTVVLGCGGGAWLVRRLGL
                     WRAFTAGVSCAGAAALLWFAQAGGWLPVSPSWAWLCTVLGSLATGITSVSIMTAGMRFA
                     GGSDQAGTDVTAVQSTRDLGELIASSTILSLTAKVGYTGGFLTGAALAVLAALIAMRLK
                     RRESAYAVKGDDALA"
ORIGIN
        1 tcactcgacc gtcgacgaag ccgacacccg tgccgggtca tgcgcatccg gtgccgcctc
       61 cacccccgcc tccacatcac gcacgcggat cgccgcctgc atgcccgaca gcttgagttc
      121 ggtttcctga tattcgttga ccggctcgga atcggcgacg atgccgcagc ccgcgaacag
      181 ccggcaggcc ccgccgtcga ccagcgcgga gcgcagcgcg acgatgaagt cgccgttgcc
      241 gtgcgcgtcg atccagccga cgggcgccgc ataccagccg cgatcgaatc cttcatgcgc
      301 gcggatgtgg tcgagcgccg cgtcgcgtgg atggccggcc accgccggcg tcgggtgcag
      361 cgccgcgatg acctgcaaga gcgtcgcgtc cgccttcagc gtcgcgcgga tcggcgtgct
      421 caggtgctgc agcctcggca gccggtgcag cgacggttcc ccgggcacgt cgagcgcgcg
      481 cgacagcggc gtgagcgcgg cgcggatcgc gtcgacgacg agcgcgtgtt cgagccgctc
      541 cttggcggaa gccatcaggg ccgcgccgag tgcgcgatcg tcgtcgggcg tggtgccgcg
      601 ccggatcgtc ccggccagcg catgcgtgcg cacgtcgccg gccgcgacac gcgcgagccg
      661 ttccggcgtg gcgccgacga agcaggcgcc ttcacggcgg accgcgaaca ggtgcgcgtg
      721 cgcgtcgcgc gtgcgcagcc ggcgcagcag cggcgcgatg gcaatgggcc gcgcgtattg
      781 ttcgagcacg tcgcgcgcga gcacgacctt gccgaacgcg ccgccgtgga tcgcgtccac
      841 cgcgcgccgg acttcgtgct gccattcgct cgcctgcagc gcctgcgtgt gcagcagatg
      901 cggtgcagcg tcgtcgcggg cggccgcgag cgtgccgagc gactcgatgc gcgcgagaca
      961 cgcatgcgcg agcgcggcag gatcgtcgtg cgcggcgacg acgtgctggc agacggccca
     1021 gtgcgcgtcg ccttcgcgca cgatcagcag cgtcgccacc gtcatgctgg cgtcgggaaa
     1081 cggcgcccag tgcgcgctgc gcgcgccgcg cggatcgaac cggaagccgc cgacggcgcg
     1141 cggcggctgc gggccggccg tcacggcatc gcgaacgagc gtgcgccagc gcgcatcgat
     1201 ctgcgcgaag cgcgtgtcgc cggtggcggt cagttcgagc gcgctgtccc agccgaacag
     1261 cgtgacggat gcatcgccgg cttcgtggaa gaaccacggc gtggccccgt cgtcccacgc
     1321 ggcgatcagg tcgaagaagt cgagcggccg caccggcacc gacaccgacg cgagcgtcgg
     1381 cgtgccggtg tcggcggcgc ggcgggccgc acgggcgaac gtgtcgtgca gcagcgggag
     1441 gccggcgttc atgcgagccc ccgttgccgg cgccaatgct gcgtctgctg cgcgatgtac
     1501 cacgcgatca ggccggcgaa cagcgtctcg acgtagtcgc cgtcgaggcc cgcctgttcg
     1561 gcccagcggc gccggtcggg cagcatcgcg gccacgcgtt ccggcgcggc gatgctcgct
     1621 tcgtcgggct tgaagcgcga tgcggccttc acgtattgca tgcgccggcc gagcgcgtcg
     1681 atgatgtcgg cgtccaggcg atcgatggct tcgcgaatgt cgggcagccc cgtgcaggcg
     1741 tccggtgttt tcatgtgtac tcctttccgt aacgaaggga ttggtcgatc cgttcgacca
     1801 gatgcgcgat cagcgccggg tactggtgcc gcaggtagaa gtggtcgccg ctgaacgtct
     1861 cgatgcggat cgggcgcgac gcgacgtcct gccacgcgcg cgcttcgtcg tcgtcgagct
     1921 cggaatcggc cagcggcagc atcacgccga gcggcgtgtc gagccgcggc ggccggtcgc
     1981 ggcgatacgt ctcgatcgca cggtagtcgt ggcggatcat cggcaggtag atcgcgcgca
     2041 tctccggatc ggcgagcagc gcggcgtgct cgccggacag ccgcgcgaca tcggccacga
     2101 gcgcgtcgtc ggattgcagg tgcagatcgg acaggcgctg acgatgcggc ggcggcaacg
     2161 cggatacggc caggtaaagc ggggccgcgc cgcgtgcctc gagccgcgcc gccacctcgt
     2221 acgcgagcgc cgcgccgagg ctgtgcccga acagcacgag cggcgcgtgc gcatagcgtt
     2281 gcagcgcgtc ggcggcgggg ccggcgaggg cgtcgatcgt cgtcaggcac ggttcgccga
     2341 agcgttcctc gcggcccgga tactgcagcg cgagcaggtc gacgtcccat ggcagcgcgc
     2401 ggctccagtt gcgaaagaaa ttcgcggtgc cgcctgcatg cgggaaacac acgagctgcg
     2461 cgcgcgggca cggcgacagg cgcagctcgc ggatccagtt cgaaccggtc ggtcgcgcgc
     2521 tcatgcggcc gccgcctgca actggcggcg cagcaggtcg cgcagcgatt tcttgctggt
     2581 cttgccgatg ccggtttccg ggaagcgcgg catgaactcg atgcgatcgg gaatcttgaa
     2641 ggcggcgagc ccgcagtcgc gcaggtagcg tttcagcacc agcctggacg gcgcgggtgc
     2701 gcgtgcgacg acgaatgcgc acgtgcgctc gccgagcagc gggtcgggca tcgcgaccac
     2761 cgccgcgtca tgcacctgtg ggtgcgcgag cagcaggttc tccacttcct cggcggagac
     2821 cttctcgccg ccgcgattga tctggtcctt gtcgcggcct tcgacgacga ggtcgccgtc
     2881 ggcggtgcgc cgcacgcggt cgccgctgcg atagaagccg tcggccgtga acgcggctgc
     2941 attgtgctcg gcgagccggt agtagccgcg tatcgtgtac gggccgcgca cctgcaactc
     3001 gccgatctcg ccgggtgcga ccggttctcc ggcgtcgtcg acgatgcgca cttcgtcgcc
     3061 gtccgacacg ggtcggccct gcgtatgcgc gatccgttcg ggcgaatcgt cgagccgcgt
     3121 gcagcagatg agcccttcgg ccatcccgaa cacctgttgc agccggcagc cgagcacggg
     3181 cgtcacgcgc gcggccgcgt ggtccatcaa ccgcgcgccg ccgacctgca gcacgcgcag
     3241 gctcgacagg tcggcccggc gttgcggctg ttcgtcgagc cacagcagcg cgagcggcgg
     3301 cacgagcgcg gtatgcgtga cgcgttcctg cgcgatcagc gcgaagctct gttcgggctc
     3361 gggccgcccg gtcgcgacca cgcggccgcc cgcgagcagc gcaccgattg tgccggggca
     3421 gcacagcgtg aagttgtgcg ccatcggcag cgcggcgaga tagacggtgc cggcgtcgaa
     3481 tccgctcgcg acgctgcacg cacgcacgtt gtacaggtat tcgcgatggc ggcgcgggat
     3541 cagcttcggc gtgccggtcg tgccgcccga cagctggaag catgcgatgt cgtcggcgcg
     3601 tgccgcgcat tcgcgcagcg gcggcgcgtc gtacagcgcg tcgaatggtg tgaacgcgtg
     3661 atcgtcgccg tccatcacga cgtgctcgag cgtcgggcag tcggcctgca acgcggccgc
     3721 gagcggccgg cagtcgaact cgccgaggtg tgccgcgcac agatacgcgc gcgcgccggc
     3781 gaagcggcag aacgcgccga tctcgtagtg ccgttgggca ggcagcgcga gcaccggccg
     3841 caccccgagc tggaacagcg cgaagcaggt ttcgatgaag cgtgcgccgt tcggcagatg
     3901 gacgacgacc gcgtcgccgc gcgccaggcc caggcgcgcg aggccgcccg caagctggcg
     3961 gatgcgtgcc agcaggtcgc gatagccgag ccggcaggtg ccgtcaacga ccgcgagcgc
     4021 gtcgggcgcg cgctgcgctt gcgcgtcgag cgcctcgaag aacgtcgtgt cctgccagta
     4081 gccggcgtcg cgatagcggt gcgcgaagtc gtcgggccag tcgggcgcgt cggccgggat
     4141 ggccggcgcc acggagggaa gggaagagtg catgcgctga ccttgggttc cggcaagttg
     4201 tcaaaaaatg taaatgagag gtattatcat ttgtaacaag tgccgcgata acgtcgtttc
     4261 tttcgatatc gcggcaattt cattcgatcg ggcgcctgtc gcgcggcgcc cgcccggccc
     4321 ggccggagaa tcggccggtt gccgccggcg cgtgccgggc cgcgcgtgcc gcctaaccaa
     4381 cggacctccg atgagctcga cctccttcgc ttcgtcacga cgtcacccgc cggtgctcgt
     4441 gcccggcaat catccgggcg tggtgcacat cgacgcgggc atgaaactca tgagcggcac
     4501 gctgtgctcg gacagccgcg actggtacga ggagccgctc gaaaaagggc tgaagctcgt
     4561 cctcgtgcag agcgggcagt tgcgctgccg cgtgccgggc cagcccgagc agtgcatcaa
     4621 ggggccgggc ctgtgcgtga tcgccaacga cggcgaattc acgacgcacc agatctacga
     4681 ccgcgacgtg ccgctgcgct acacgatcgt gcagctcggc ctcgatgcgc tcgaccgcaa
     4741 cctgagcctg ttgccggaga agatgctcgc gccgacgggc ggcgatccgc gcatcgtcag
     4801 ttgcccggca tcgaaggcgc tgcaggcgct cgcggtacag atcgcgacgt gcccgttcga
     4861 gggcgcggtg cgcgagtact acctgaaggc caaggcgttc gagctgaccg cgctgagcgc
     4921 gcagctgctg gcgacgcagc ggcagttcgc gccggccgac gtgcgcgtca cgtcgtcgga
     4981 cgtcgagcgc gtgtacgcgg cgagcgacat cctcacgcgc gagctccagc agccgccgac
     5041 gctcgatgcg ctcgcgggcc gggtggggat gaattcgcgc aagctgacgg ccggcttccg
     5101 caaggtgttc ggcacgagcg tgtatgcgta cctgcaggaa taccggctgc ggaccgcgca
     5161 cgcgatgctg tgcgcggagg acgcgaacgt gtcgaccgtg gcgtaccgcg tcggctacag
     5221 ccccgcgcat ttctcgatcg cgttccgcaa gcgctacggc atttcgccga gcgacattcg
     5281 cgcatcgtcg aacgcgatcg acgatgccga actggagagc gcggcaatct aaaacaactg
     5341 accggccgcc taaagcaatc gaccgggctc atgggcgtga atgagataga ttctcattca
     5401 cgggtggccg ccgccgcgcg gatccgccat cgaacgaccc atacaaggcg tgcccatgag
     5461 ccagaccgct gtcgattcaa ccatcgatca ttccgatcct tcctgttttt ctcccattgc
     5521 ctttcgctcg cagctcgtcg cgatgatcgc ggcgctgctc gacgagcccg tcgacgaaat
     5581 cgcgtcgctc gacgatgacg aggacctgct gagctgcggc ctcgattcga tccggctgat
     5641 gtatctgcag acgcgcgtga accggctcgg ctacgcgctg acgttcgacg cgctcgcgcg
     5701 tacgccgacg ctcggcgcgt gggccgagct gctcgcgaat gcgccgcgcg gcgcatccgc
     5761 ggcgcccgac gtcgaagccg ccgaggccgc cgaggcggtc gatgtcgacg tgcatgcgcc
     5821 gttcgacttg tccgcggtgc agcaggcgta ctggcttggc cgcggcgacg gtgaagtgct
     5881 cggcaacgtg agctgccacg cattcctcga gtttcgcagc cgcgcgatcg atcccgttcg
     5941 tctcgatgcg gcgtgccgac tcgtgcgcga acgccatccg atgctgcgtg cgcgctttgc
     6001 cggcggccgc cagcagatcg tcgcggcacc cgaggcgccg gtgttcgcgc atgcggactg
     6061 gcgcgaccgg acgcccgccg aagcggaaac cgaatgggtg tcgctgcgcg cgttccggtc
     6121 gcacgaatgt ctcgacgtcg agcacgcgca ggtcttcatg atgggcctcg cgcagatgcc
     6181 cggcggcgag gatcgcgtgt ggctgagcgt ggacctgctc gcggccgacg tggacagcgt
     6241 gcggctgctg atgcaggaga tcggtgccgc gtatgccgag ccgtcggcgt tgcccgacgc
     6301 gccgtcgacg tggtttccga cctggctcgc gcgtcgcgcg gccgatacgc gcgatgcgcg
     6361 ggccgcggcg cgcgatgcat ggcaggcgcg gctcgcgaca ctgccggaag ggccggcgct
     6421 gccgctcgcc cgtgcgccgg aaacgatccg cgcgccgcgt ttcagccgcg tcacgcatac
     6481 gctgagcacg gccgaactga cgcgcctgca ggcgcgggcc gcgcagcatg gcgtcacgct
     6541 gtcgtcggtg ttcggtgcgg cgttcgccgc ggtgctcgcg cgctggagcg gccggcaggc
     6601 gttcctgctc aacgtgccgc tgttcgaccg gcacggcgat gcgcccgatc tcggccgcgt
     6661 gatcgccgat ttcacgacgc tgctgctcgt cgaatgcgac atgcgcgccg acgcgagcgc
     6721 ggccgacacg gtacgcgcgt tccagcagcg gctgcacggc gcgatcgcgc aggctgcgta
     6781 tccggcgctc gacgtgctgc gcgatgcacg caggcagggc gcgccgcgcg cggcgcccgt
     6841 cgtgttctcg tgcaatctcg gcgacgcgcc gttcgtgccc gacgcattcg cgcgcgtgtt
     6901 cggcgatctg cacgacatga tttcgcagac gccgcaggtg tggctcgatc accagctcta
     6961 tcgcgtgccg gacggcgcgt tgctcgcatg ggacagcgtc gacggcctgt ttcccgacgg
     7021 gatggtcgat gcgatgttcg gcgcgtatgt cgcgctcgtg caggcgctgt gcgatcgcga
     7081 ctggcggctg ccgatcgcgg tcgaactgcc gtccgcgcag cgacgcgtgc gcgatgcgct
     7141 caacgcggtg cccgctcccg cgcggccgcg cacgctgcat gccgacttct ttgcatcggc
     7201 cgcgcgcgag ccggcggccg tcgcattgcg gtgcgccgag cgcgtggtga cgcgcggcga
     7261 actggccgcg caggcgctgg cgatcgcggg tggcctgcgt gccgccggca tcggtcacgg
     7321 cgatgccgtc gagatcagtc tgccgcgcgg gccggaacag gtggccgcgg tgttcggcgt
     7381 actggccgcc ggcgcgtgtt acgtgccgct cgacattgcg cagccggccg cgcgcaaggc
     7441 actgatcgaa cgcgcggccg gcgtgaaggc cgcgatcggc gatacggcgc acgcggatgc
     7501 gccgctgccg cgcttcgatg ttgcatcgct gatgaaacat gcgccgctgg ccgcgccgct
     7561 cgcggtggcg ccgcaggcca ccgcgtacgt gatctacacg tccggttcga cgggcgtgcc
     7621 gaagggtgtc gagatgacgc acgcggcggc gctcaacacg atcgacgcaa tcgatgcact
     7681 actcggcgtg cgtgcgcaag accggctgct cgcggtatcg gcgctcgatt tcgacctgtc
     7741 ggtgtacgac ctgttcggcg tgctcggtgc cggcgccgag ctcgtgctgc cgacccagga
     7801 cgacgcgcgc gacgcggcgc gctggatcga cctgatcgcg cagcatcgcg tgacgctgtg
     7861 gaattcggcg cccgcgctgc tcgaaatggc gctggcggtg cccgccgcgg ccgacgcatg
     7921 ccgcagcgtg cgcgcggcgc tgctgtccgg cgactggatc gcgctcgacc tgccggcgcg
     7981 cctgcgcgaa cgatgcggcg acgcatgtgc gttccatgcg ctcggcggcg cgaccgaggc
     8041 cggcatctgg tcgaacgtgc agacggtgcg cgacgtgccg ccgcactggc gttcgattcc
     8101 gtatggccgg ccgttgccgg ggcaggccta tcgcgtcgtc gataccgacg gccgcgatgt
     8161 gccggattac gtgccgggcg aactgctgat cggcggcgac agtctcgcgc gcggctaccg
     8221 caacgatccc gagctgaccg cgcagcgctt cgtgcagcac gcgtcgggcc gctggtaccg
     8281 cacgggcgac cgtggccgct actggcccga cggcacgctc gaattcctgg ggcgcgagga
     8341 tcgccaggtg aaggtgcgcg ggcaccggat cgaactgggc gagatcgagg ccgcgctggc
     8401 cgcgcatccg cagatcgacg gtgcgtgcgc gagcgtcgtg aatggcgaag ttgcgcgcat
     8461 cgtcgccgcg ttcgtgccgg ccgattgcgg tgccgcttgc gttgccgatg cagcgccgtc
     8521 gtcgctcgcg gaggccgacc tggccgatac ggttgaggcg gaagcggccg ttgcgcgcgc
     8581 cgtcgccgat cggctgctcg atggcggcgc gggcttgccg ccgtcgttgc gtgcgcaccg
     8641 gcacgcgaaa agcgatgcgt cgatctccat cgacggtgcg ctcgatcggc tcgactggta
     8701 tgcaaccgat ctcgacgatc tgacggcgtc gctgcgcgcg ctcgcagccg atccggatac
     8761 cgccgcgcag cgcgtgccgc tggacccatg cgtggcaccg cttgcgttcg cgacgcgttt
     8821 gccggacggc gcgcgcgcgc tgcgcgagtt tgccggcgcg ctggaggcac aggccgctgc
     8881 acgcacgggg ctgctgcggg tcgcggtggt cgacgcccgc gccgggcaat ggttcgaagc
     8941 gggcctcggt gtgctcgacg atccacgttt cgatgtgacg ctgtttgacg tgtcgccggg
     9001 gctgctgcac accgcacagg cacgcttcac ccttacgagg cccgcgcttc aggcgatgca
     9061 ggacggcttg ttgcccgcgc ggcatctcgg cgaattcgat tgcgtgatca gtttcgcggc
     9121 cgcgcatctg cgcgacgatc cgcgcgatac gttccggatc gcggcagcgt tgctggcgca
     9181 ggatggccgc ctgctgttcg ccgacgtgct gcgcgactcg ccgttgcgtg aactcgtcgc
     9241 gagcgtggcg ggtgatgcgt cgttgccgcg gccgttcacg cccgatgcga tcgccgccgc
     9301 cgcgcatgcg tgcggttttg cgctcgactc ccgaagctgg cgttcgaacg cattcgcgtg
     9361 catcgacgcg cgccgtaccg gcgaaccggc cgcgcaagcg gcgctggccg actggctgcg
     9421 cgaccgcttg cccgacgcga tgcgccccga tgcgctgtgg tgcatcgcgc gctggccgct
     9481 caacgcgaac ggcaagatcg accggcgggc ggtgggcgag gcgctcgcgc gcgcgctcgg
     9541 cgacgcacct gccgcccacg atgcattcgt gccggccgac gaacggcagg cgacgctgct
     9601 cgcatgctgg gagcacgcgc tcggccgccc ggcgaacgcg cgcgacgcga cgttcttcgc
     9661 gctcggcggc gacagcctgc tcgcgacgcg cctgctcgcg caactgcgcg agcggctcgg
     9721 cgtgcgggtc gggatggcgg cgttctaccg gcagccgacg ctcgcgggtc tcgccgcgca
     9781 gctcgacgag gccgcaccgg ccgcgccggc cctgcaagcc tcgcaggccg acggcgacac
     9841 gccggttgcg acgatcgagg agggcgtgct gtgagcttcg atgacgtgct cgatctttgc
     9901 cgcgaacgcc ggatcgaact gtggtgcgac gacggcggcc agttgcgcta tcgcgcgccg
     9961 gccggtgcgc tcgatgcgga cctcgccgcg cgcatcaagg ccgaacgcga cgcgttcgtc
    10021 cgcttcctgc aggacggcgc atggcgctgc gatccggtgc gccggcacga gcggttcgca
    10081 ctgacgccgg tgcaggccgc gtacgtgctc ggccgccacg aatcgttcga gttcggcggc
    10141 aatgcgtgcc atctgtacgt cgaatatggc gagcccgcga atctcgactg cgtgcgcttc
    10201 gaggcggcgt ggaacgcgtg cgtcgcgcgg catccgatgc tgcgcgcgat cgtcgaggac
    10261 aacgcatggc aacgcgtgct gcccgacgtg ccgtggcagc cgctcacagt gcacgacctg
    10321 cgcgatgccg acgcgaacgc gttcgacgcg cacgtgaagc gcgtgcgcga gcgtctcgac
    10381 catgcggtgc acgcgctcga ccgctggccg gtgctgcagc cggaagtgag cctcgggccg
    10441 gacggtgcgg tgctgcacct gtcggtcgat ttcacgctga tcgactacgc gagcctgcaa
    10501 ttgctgctcg ccgaatggcg gcgccgctac gacgacccgc agtggcagcc cgaggcgctc
    10561 gacgcgacgt tccgcgacta cgtcgtcaat gaagcccatg ccggcacgcg cgcggaacat
    10621 gcgcgcgaca aggcgtggtg gcttgcgcgc atcgacgatc tgccgccgcg ccccgatctg
    10681 ccggtggtgc ccgcgatgcc gtccggcgca cggccgcgct tcacgcaccg gcatgcgcgg
    10741 ctcgatcgtg cgcaatgggc cgcgctgagc ggccacgcga gccgcttcgg cttgagcgcg
    10801 gcgagtgtcg cgctggccgc gttcgccgaa gtcgtcggcc gctggagcca gtcgcccgcg
    10861 ttctgcctga acctgacggt gctgaaccgg ccgcccgtgc atccgcgcat cgacgcggtg
    10921 ctcggcgatt tcaccgcgct gagcctgctc gcggtcgacg tgacgcacgg gcgcgatttt
    10981 gtcgagcgcg cccgcacgat cggcgcgcgg atgttcgacg acctcgacca tcgtgcgttt
    11041 accggtgtcg acgtgatgcg cgaactcgcg cgacggcgcg gcaaggatgc ggcgctgatg
    11101 ccggtggtgt tcacgagcgg catcggcagt gtcggccggc tgctcggcga gcacgcggcc
    11161 cgcgccgagc cgccgcgcta catgatcagc cagacgccgc aggtgtggct cgactgccag
    11221 gtgaccgatc agttcggcgg cctggaaatc ggctgggacg tgcgcgacga cctgtttccg
    11281 gacgggatgc ccgcggcgat gttcgacgcg tacgtcgccc tgctgggccg gctcgccgcc
    11341 gacgcggcgt ggtggtcgcg cgcgggcgac atcgtgctgc cgtccgctgc gcccgccgcc
    11401 gggatccatc cggatgcgga tacgcacatc gcggccggct tcgccgcgca ggcgttgcgt
    11461 acgcccgacg cgccggtggt gatcgatgcg cagggggcgc gcacgtatcg cgacgtcgcg
    11521 cagcacgcgg cggcgctgcg gtcggcgctc gaacaggccg gcgtcgccgc gggcgatacc
    11581 gtcgcggtgc tgatgccgaa atgcgcgcac cagctcgtgg ccgtgctcgc gatcgtccag
    11641 gcgggcgccg cgtacgtgcc ggtcgacagc cgccagccgg cgctgcggca acaggcgatc
    11701 ctgcgcaatg cgcgggtgcg tgcggttgtc agcgtgcagg cgctcgagtt cgaacacgac
    11761 gggtgcgtgc gcatcgatgt cgatgcagtg ccggtcgatc cgcaatggcc gccgcgcgcc
    11821 gcgcgcgaca ttcccggcga cgcactcgcg tacgtgatct atacgtcggg ctccaccggc
    11881 gagcccaagg gcgtgatgct gagccacgcg gccgtctgca acacgctggc cgacatcagc
    11941 gcgcgccatg aagtcggcga cggcgacgtg gtgctcggcc tggccgagtt gagcttcgac
    12001 ctgtccgtct acgacttctt cggcgcgacc gcacgcggcg cgtgcatcgt gctgcccgat
    12061 ccggcgcgcg gcaacgatcc gtcgcattgg gccgcgctga tggcgcgcca tcgcgtgacg
    12121 ctgtggaatt cggttcccgc gcaagggcag atgctgatcg attacgtcga aggcgaaccg
    12181 gcgctcgatg tgccgggccc gcgccgcgtc ctgtggtcgg gcgactggat tccggtgacg
    12241 ctgcccaccc gctggtggcg gcgctggccc gacagcgcgc tgttcagcct cggcggcgcg
    12301 accgaggcat cgatctggtc gatcgagcat ccgatccgtc cggcggacac gcagctggcc
    12361 agcattcctt acggccgcgc gctgaccggg cagacgatgg aggtgctcga cgcgctcggc
    12421 cggtcatgcc cgccgggcgt gcgcggcgag atccatatcg gcggtgtcgg gctggcgacg
    12481 ggttacgcga acgatcccgt gcgaacggcg gaacgcttca tccgtcatgg cgacgggcgg
    12541 cgactctacc gcaccggcga tctcggccgc gtgcgcgccg acggttcgct cgaattcctc
    12601 gggcggcagg acgatcaggt gaagatccgc ggctaccgga tcgagctggc cgagatcgat
    12661 gcggcgctga ccgcgcatcc gctcgtcggc gcggccgcga cgatcgtgct cggcgacggc
    12721 acggagcgcc ggctcgcgag cttcgtgtcg ctgcacggcg cggagccgcc gcagcaggac
    12781 gacgcgctgc acgagatcgc ggcgcacgtg cgcacggcgt tcgatgccgc gcgctggccc
    12841 gcgcacgcgg acgtggcgcg gtcggttgcc cgactcgaag cggcctgcgt tgcatcgctg
    12901 gcagcgtgga tcgtgccggc aggggcgctg accgaggagc aggcgacgga cttcgcgacg
    12961 ttgtgcgaac ggttgcgcgt gccggcggcg cgacagcatc tgctgcgtca ctggctcgcg
    13021 atgctcgacc ggcatggcgt gctgcacgcg gatgccgaag gcggctggcg caggcggccc
    13081 gatgccggcc atgccgatgc gcatgcctgc tgggacgcgt ttgcgcagga tgcgtcgccc
    13141 gatctgtggc cggccgtcct cgtcgactac ttccgcgaca gcgcgggatg catcgacgta
    13201 caggtggacg gcaccgtgtc gcccgccggc ctgatgttcc cggaaggcgc atcgcatatc
    13261 gccgacgcga tgtacagcga cggcgaacat gcgcgggccc tgcacgacgg aatggcacag
    13321 gcggtgcgtg cgatcgtcgc gcgcgagccg cagcgcccgt ggcgcatcct cgagatcggc
    13381 gcgggcacgg ccgcggcgac gcgggcgatc gtcgacgcgc tcgcgccgct ggtcgaagcg
    13441 ggcgtgcgga tcgactacct gttcagcgac gtgtcgagct atttcctcgc ggcggcacgc
    13501 gagcgcttcg ccgcgtatcc gtggatgcgg ttcgagcggt tcgacatgaa cgcggcgctc
    13561 gacgcgcagg gtattgcgcc gcattcgatc gacatcacga tcagctccgg cgcgctgaac
    13621 aatgcacgcg acacggtcgc gctggttgcc ggattgcgcg cgctgtcggc ggccgatgcg
    13681 tggtgggtga tccaggaact gacgaccgag catccggaga tcagcatcag ccaggggttg
    13741 atgatggaaa cgccgcacga cgcgcgcgtc gaatcggcgc gtctgttcgt gccgcgcgcg
    13801 cagtggctcg aatggctgca agaggcgggc ggcgatcgcg cgctcggttg cgtggcaccc
    13861 ggcacgccgc tcgacgcact cggctacgac atcctgctcg cgcacgtgaa gcgcggtgcg
    13921 gcgcgcatcg cgccggacgc gctgctggca tgcgtcgcgg agcgcgtgcc gggctacatg
    13981 gtgccgtcgc aattgcgcgt gctcgaccgc ctgcccgtga ccgcgaacgg caagatcgat
    14041 cgccgcacgc tggccggcat cgccgacatc cgcgaaccgg agccggcggc cgcccggccg
    14101 gctcacgcgc aggccgccgc cgatccgctg ctggcgcggc tgatcggctt gtgggaagcc
    14161 gtgctcgata cgcgcaacgt cacgcccgat caggacttct tcgccgcggg cggcgattcg
    14221 ctgctgatcg cgcaactcgt gtcgcggctg cgcggcgagg aaccgctcgc gcacgcgcat
    14281 ccgttcgacc ggttgctgcg ctgggtgctc gcgcaaccga cgcccgccgc gttcgcgcaa
    14341 tgcctgcgcg acgcggatgc gcggccgtcg ggcagcgcat cgccggttgc gccggccgct
    14401 ccgcgcagcg cgcacgtttc ggcggtcgtc catgcgccgg cgccgcgcgt gcgtgccggc
    14461 gtgcggccga tcacgctcgc acccggcgac ggcgtgccgc gcgtgatcgt gcatgaaggg
    14521 ctcggcaccg tgcatgcgta tcgtccggtc atgccggcgc tcgcgcggct cggcccggtg
    14581 ctcggcttcg cggtgcgcga cgcgcaggac tatctcgacc tgccggcgcg ccacctgaac
    14641 gcgacgctcg gccggcgtta tgcggatgcg ctgtggcgca ccggcgtgcg cgaggtcgac
    14701 gtgctcggct actgctcggg cgggctggtc gcgctcgaaa tggcgaagtc gctggtgcag
    14761 ctcggcgtcg aggtgcgcac gctcgacatc gtgtcgagct accggattcc gtacctgatc
    14821 gaagacgagc ggctcgtgct gttcaacttc gcggcgacgc tcgggctgcc gctcgacgcg
    14881 ctcgggtttc cggaaacgta cgtgctggcc gacgcactcg ccgacgcatt gaaggccgac
    14941 cccgcgcgtc tcgcgcccgg cagcctgcag gcccagctgg agattttcgg cgaccgctgc
    15001 gagccgctcg acacgttgcg ccgccgcgtg ctgcgcgcgg ccgccggatt gtcgatgcag
    15061 gacgaggtcg cgcacccgct gctcgacgag cgcgaacggc tgtaccggct cttcatgcat
    15121 tcggtgcagg cgagccactg ggcgggcgac gcgccgtacg cgggtgcgct gcggctgttc
    15181 gtgccggagc gctgcaaccc gctgattccg caacagcgcg cggcgctcac cgaatactgg
    15241 acggcgcagg cgctcggcgg catcacgtcc gtcgacatcc ccggcggtca tttcgactgc
    15301 ctgaacgccg cgttcgtcga cacccgcctg aaggaggcgc aatgaaggct catccgctgc
    15361 cggtcgtcgt ggccggctcc cgcttcggcc agttctatgc ggcgggcctc gccgcgtccg
    15421 gcacgtatcg cgtcgcaggc atcctggggc aaggcagcgc gcgtaccgct gcgctggccg
    15481 cgcgcgtcgg tgcgcccgtg ttcgaccgtc cggaagcgtt gcccgacgac gtgcgcgctg
    15541 cgtgcgtcgc ggtcggcggc gcggcgcgcg gcgccgacgg ggccgcgctc gcgtgccggc
    15601 tgctcgagcg cgggatcgac gtcgtgatcg agcatccgct gctgcccgac gaatgggacc
    15661 gcgtgctgcg caccgcgtcg cgtcatggcc ggcgctgcct gctcaacagt ttctatccga
    15721 acctgccggt cgtctcccgc ttcatcgccg tcgcgcgacg gttgcgtgaa acgagtgcgc
    15781 ccgtgcatgc ggatgtcgtg tgctcggtgc aggccagtta cgcggcgctc gacgtgctcg
    15841 ccgccgcgct gcagggtgta ggcccgtggt cggtcgagcc ggtcgggccg gcactgtcgt
    15901 cgatgcgcga atgcgcgatg gtgctcgccg aaacgccggt ctcgctgcgc gtgcacaacg
    15961 agatggcggc ggccgacgac ggccggatga gcatgctgtt cagcatcacg ctgacgacgg
    16021 acgccggcac gtggacgctc gcgtcgccgc atggcccgct gtggtgggcg cccgcgctgc
    16081 gcgaaccggc gacggacgac gacgggctgt tcccgatttt cggcgacgcg gcgggcgacg
    16141 acatgccgag catccagatc tgcgacgatg cgcgcgatac gtggggcgcg attcatgccc
    16201 gcagctggcc gcaggcggcc gtgcgcgcgg tcgaccggct cgtgtcgggc gaagggttgc
    16261 acgcgtgcaa ccagcgcagc atcgacgtga cgcgcgtctg gcagcaactg acgatgcagc
    16321 tcggttttcc ggagcagccg ccgggcgacg cgtgcgcggc cacgctcggc atgctgctgg
    16381 agcgtgccgc atgaaggggc cgttgctttc gatgttgcgg ccgttcgcgg cgccgcttgc
    16441 ggcggcggtc gtgctgcagg cgctggcggg tgtcgcgtcg ctcgtgccgt ggctcgcgct
    16501 cggccgtatc gccgacgcat ggcgcgcgac ggcacagctc gacgcgacgg cgcgcggctg
    16561 gctcgtcgcg gccgtggtgg ccggcgtgtg ctggctgggc ggccagacgg tcgcgctgca
    16621 cctgacccac cgtgtcgacg ccgatctcgc cgaccgcttg cgcaggcggc tcgccgatca
    16681 tctgcaacgc ttgccgctcg gctggttcgc gcgagcaggc agcgaccgcg tcgcgcgtca
    16741 cgtcgaccag gacgtgcgcg cgctgcacca gctcgtcgcg cacgcgccgg ccgacgtcac
    16801 gcaactcgtc gtcgtgccgt gcgcggcgct ggcgtgcctg ctttacctga atcccgggct
    16861 gctcgccttt gcgctggtcc cgctcgtcgc gggcgccgcg ctgttccgct ggatgcgctc
    16921 ggcgcggttc gtaccggccg tcgcggcgcg caacgcggca ctcgaacagc tgatgggcga
    16981 ttacgcgcag ctcgcgcaga acccggcgct cgtgcggcag tatccgggcg ccggcatcga
    17041 ggcggccgtg ctcgcgtcga ccgggcgctt cgaccaggcg ttttcggcgt gggtcggccg
    17101 cgtcggcggg cccggtgcct gcacgcaggt gctgctcggc acgccgttcc tgctcgcgtg
    17161 ggtcgtgttc ggcgcgacgt ggctcacggc cggccgcctg ccggtcggcg aactgtgtgc
    17221 gttcgcgctg ctgatctggg cggttgccgc gccggtgcgg gcgctcggcc acggtgccga
    17281 cgcgttgcgt gaggcgcgcg cggccgctgc gcgcctcgat gcgttgctcg cgcagccggg
    17341 cctgcccgag ccggccgatg gcgcggcgca ggtgccgcgc gatgcgtcga tcgagctgcg
    17401 cggcgtgagc gtcgacatcg acggcacgcc gatcctgcgc gacatcgacg cggcggtcgc
    17461 ggcgggcacg accaccgcga tcgtcgggcc gtcgggtgcg ggcaagagca cgctgctgat
    17521 gctgctcgcg cgcttcatgg atcccgaccg cggcacggtg cggctcggcg gcgccgacct
    17581 gcggctgctc gcgccggaca cgcggcgcga gcaggtggcg atggtgttcc agcaggccgc
    17641 cgcgctcgac gtgtcgatcg ccgcgaacat cgcgctttac cggcccgatg ccgatcacga
    17701 cgcgattcgc gcggccgcgc gcgcggcctg tctcgacgaa cggatcgacg cgttgccggg
    17761 cggctacggt tgcgtgtgcg ggcgcgacgt gcggctgtcc ggcggcgaac tgcagcggct
    17821 ggcgattgcg cgtgcgctgc tgtcgacggc gccgctgttg ctgctcgacg aaccggcgtc
    17881 ggcactcgat ccacaaaccg cgcgtgcatt gcgcaatgcg ctgcgcggcg acgcgcgcac
    17941 gcgcgtgatc gtcagccacg atctcgacgc gatccggcag gcggaccaga ttctcgtgat
    18001 ggatcgcggc cgcatcgtcg agcgcggcac gcatgcggcg ctgctggccg cgtgcgggct
    18061 gtatgcgcgg ctgtggcgcg aacgcggtgc cgcggacggg gaggccgcat gatggtgaaa
    18121 tcgctcaaac gtttgcagtg cctgccatcc ggcacacgcc gcgcgctgtg gcgcggggtt
    18181 ggctgggcgg tggcggccgc gttgctcgac ggcgcttgcg gattgctgct cgtgccgttg
    18241 atccgcgcgt ggttcgctgg cgcgcagggg gccgtgttgc actggacgat cgtgctcggt
    18301 gcgctgacgt tgtgccatgc attcgtgctg tacgtcgcgc agcgcggcgg ctatcgcgcg
    18361 ggcggcgcgc tcgcggccgg tctcgtcgaa cgcctcgtgc ggcacctgcc gcgtatcgcg
    18421 tcgtggcaga ccgtgcgcga cagtcatccg gccgggctgc tgcgcgggcc ggtcatgcag
    18481 gcgatgggga ttccggcgca cctgctcggg ccgctgatcg gcgcggtcgt gacgccgctt
    18541 gcggtcgtcg ccgggctcgc gtggatcgac tggcgcatcg cgctgtgcct cgcggcagcc
    18601 gccgtgttgc tgttcgcact gctcgagcgc ggcggcacgc gcacccttgc gttcgagcag
    18661 gcgcgcgcgt ccggcgatcg cgacatggcc gtgcagcttc agaccttcgc cgcgcatcag
    18721 gggctgctgc gcttcgcggg ccgggaaggc gacgcgcgcg cggcgctgat gcacgcgttc
    18781 gacgcgcagc atcgccgcac gcgcgcgctg atgcgccgct cgctgccgat cgaactcggc
    18841 ttcgcgggcg cggtgcaggg cgtgttcgtc gcgatgctgg ccggcggcgc atgggccgtc
    18901 tcggcgggcc ggctcgatgc cgcgacggcc gtggcggtgc tcgtgctgct cgtgcgtttc
    18961 atcgaaccgc tcgcgcagct cacgcagctc gaccaggcgc tgcgcggcgc ctggcgcgcg
    19021 ctcgacaccg tgctcgcggt gctgcatgcg ccgcgtttcg acagccccga ccgcggcacg
    19081 ccggtacacg acgcgagtgt cgacgcggtg cgcgtcggct accgttcgcc cgccggcgcg
    19141 acgctgctgg acggcgtcga cctgcattgc ccggcgggcg gcttcgtcgc gatcgtcggc
    19201 cccacgggcg ccggcaagag cacgctgctc ggcctgctcg cgcggctcga cgatccgggc
    19261 gccgggcgcg tgctgctcgg ccgcgccgat gtgcggcacc tgagcgaggc gacgctcgcg
    19321 gcgacgcgca acctcgtgtt ccaggacaac gggctgtttc gcggcagcct cgcgtggaac
    19381 gtgcggatgg gccgcccgga tgcgaccgat gccgaactgc gcgacgcgct cgacgcggtc
    19441 ggcctgctgc acgacgccga gcgcttgccg gacgggctcg aatccgacgt ggggccgggc
    19501 ggccagttgc tgtcgggcgg gcagcgccag cgggcgtgcc tggcgcgcgc gctgctgtcg
    19561 cgtgcgccgg tgctgatgtt cgacgagccg accgcgagcc tcgacgaatc gagtgcgcgg
    19621 cgcgtgcgcg acagcctcgt cgcgctgcgc gggcagcgca cgcgcatcgt cgtcacgcac
    19681 cagccggcgc tcgcggcggc cgccgacacg atcgtcgtgc tcgatgcggg ccgcgtacgg
    19741 gcgaccggca cgcacgcgca gcttgtccag gcggacgcgt ggtacgcgac tttcgcccgt
    19801 gccgggcagc tgcccgacgg cctcgcaccg gccgaaacga tcgcggaagc ccggccggcc
    19861 gaatccgaac actgacgtga acaatgcggg ccggcgtgcc cggaatcgat aggaaaagcc
    19921 cctcgatcga aaaatggctt gccggttcta tttgataatg agaatgatta tcaaatacgg
    19981 gggcgtgaat gcggtacgag gtgctggaac ctgggagatc gatgacgaag ggcgcgcgcg
    20041 tcgcccgttc ggggcgaggg cgctggcgcc cgtcgctgta tctcggcctg ctgatcgccg
    20101 cgcatccggc ggcggcgttc gccgatgcgg cgccggcggc cggcgcggaa gtccggaagg
    20161 aggaaacgac cgccgtgaag cctgccgcgg gcgagctgaa ggcgatttcc gtgaccgggt
    20221 cgcgcggcgt ggccgacgat ccggccgtgg cgacggtcgg caagatgccg ctggcgttgc
    20281 gggagattcc gcagtcggtc agcgtgacga cgcgcgaacg gatcgaccag cagaacctgt
    20341 attcgctcga cgaggtgatg cagcaatcgg cgggcgtgac cgtgcagccg tacgtgctgc
    20401 tcaccaccgc gtatttcgtg cgcggcttca aggtcgattc gttcgaattc gacggcgtgc
    20461 cggtggtgat cggcgacatg gcgagcgcgc cgcaggacat ctccgtgtac gaacgcgtgg
    20521 agatcctgcg cggcgcgaac ggcctgctgc acggctcggg caacccggcc gcgacggtca
    20581 acctcgtgcg caagcggcca cagtaccagt tctccgcgaa cgcgagcgtg agcgtcggca
    20641 gctgggaccg ctaccgcgcg gaagccgaca tcggcggccc gctcaatgcg gccggcaccg
    20701 tgcgcagccg gctcgtcgcc gcatacgagg atcgtcattt cttctacgac cacgcgaaac
    20761 aggacacgcg ctcgatctac ggcatcacgg aagtcgacgt gacgcgcgac acgctgctca
    20821 cgttcggcgc gcagtaccag acgacgcgct cggtgcccga catgtccggc gtgccgatgg
    20881 cgcgcgacgg gtcgagcctc ggcctgtcgc gctcgacgtt cctcgacacc gcgtggggcc
    20941 acttcgactg ggacacgacg cgcgcgttcg cgtcggtcga gcagaagctc ggcgccggct
    21001 ggaaggcgaa ggtcagcggc gaataccaga gcgtgcgctc cgacctgaaa tacgcgggct
    21061 cgtacggcgc gatcgatccg gcgaccggtg cgggcggcgc gctgacgggc ggcgcgtacc
    21121 ggttcagcag ctacagccgc agcatcgatg cgaacgtgca gggcccggtg catgcgttcg
    21181 ggctgacgca cgacctgctg ttcggcgtga cctacgcgaa cagcagcagc gggcagatgt
    21241 cggcgcagct gctcggcaac gtggccggca tgccggtgaa cgtctaccgc tggaacccga
    21301 gcagcatgcc cgagccgggc gtcggcccgt accagcagtc gcagcagaac gacgtgtcgc
    21361 agaagggcgt gtacggcctc ggccgcatca agctcgcgga acccgtcacg ctcgtgctcg
    21421 gcggccggat gagctggtgg aaccaggaca gcctcggcgc gcactacaac acaggccacc
    21481 agttcacacc gtacggcggg ctgatctggg atttcgcgcg cgactggtcg tggtacgcga
    21541 gctatgcgga agtgtttcag ccgcaaacca agtcgatgtg gggcggcggc atcttgacgc
    21601 cggtgaaggg gcgcacctac gagacgggcg tgaagggcga actggcgggc ggcaagctga
    21661 acgtgtcgct cgcggcgttc cgcatcgatc tcgacaacaa tccgcaggtc gatctcgcgc
    21721 atccatgtgc cgggccgaac tgctactacg tgaacggcgg cagcgtgcgc agccagggct
    21781 tcgagttcga ggcgaacggc cgcatcacgc cgtggtggag cgtgtgggcg agctatacgt
    21841 acgacacgat gcgctatgcg gacaacctcg cgaacgcggg cacgttcgcg ccgctgctga
    21901 acccgcgcca cctgttccgg ctgtggacca actacgacct gccgtggcag gaacggcgct
    21961 ggagcgtcgg cggcggcgtg caggtgcaga gcaattactc ggcgcaggcg aacggcgtca
    22021 cgatgagcca gggcggctac gcgctcgcca gcgtgcggct cggctatcgc tacgacaagc
    22081 actggagcgc ggccgtcaac gtgaacaacc tgttcgaccg caagtactac ctgagcctga
    22141 gccagccggg ctggaacaac cgctacgggg aaccgcgcaa cgtgatgctg accgtgcgcg
    22201 ggcagttctg atggcgggcg gctgggggac gcgggcggcg ctcgcgatcg caggcgtgct
    22261 gccgggcgcg gtcgcgctgg cggtcacgct ggcccgtcat tacccggccg acggcctgaa
    22321 ccggctctac gcggcggtgc tgctgtcgct ggccgcgggt gtcgccgcgc tgctgtgggt
    22381 gctcgtcgcg cccgggcggc ggcaggccgc gtggcgcgcc tgcctgtggc tcgcggtgct
    22441 cgtgccgtgc gcgatgttct ggggagggcg ctgacatgga cgcttcatcg cgttcgcgct
    22501 ggcgcgcgct gcatcgcggc gccggtgcgc tgttcggcgt ggtgctgttc gtcgtgctgt
    22561 tcagcggcac gtggagtctc gcgaccgatt cgatgcaggg ctggtggcgc gcgccgccgg
    22621 tcgccgtcgc gcggccggcg ctgccgctcg atacgctcgt cgcgcgcgcg gcggcgctcg
    22681 gcgtgccgtt gcgcgatgcg cgcatcgtgc tgccgcaacc ggacgatccg gcgatccgtt
    22741 tctgcgacgc gcgccaggcc tgcacgctgg cgctcgaccc ggcgacgggc gagcggctgg
    22801 ccgacggcgg acgcgcggcg ttgctcgtca cgctgcacaa gacgctgttc gcgggctttc
    22861 ccgggcggat cttcgtcagc ctgtggggga tcgtgctgct cgtgctcatc gtcgcgggcc
    22921 tggtcgtgca tcaccggcgc tggcctgctg ccgcgcgcat ccggcgcggc agcgggttgc
    22981 gcgccgcgct gttcgacctg cacgcgtgga tcggcctgtg gggctcgccg tggctcgtgc
    23041 tgttcgcgtt caccggcgcg ttgtcggggc tgggcgcgct cggcacggtg tcgcttgcgg
    23101 gcgtagcgta tccggggcag ccgcagcgcg cgttcgccga gctgctcggc gggccgccgc
    23161 cgactgccgc cggcggcgcg tggcaacgcg cgcccgatct cgaggcgctg ctgcggcgcg
    23221 atgcggcgcg cacgccggat ttccggcgcg aagccgtcgt gttgcatcgg tggggcgacg
    23281 tgaacgcgcg tgtcgagatt gccgggacga ccgccggcct gccgagcacg gcgctgttcg
    23341 agcgccacct gtatcgcgcg gtggacgggc aatggctcgc ggacgccacg tcgcgcggcc
    23401 gaggcttctg gttgcgcgcg ttcatcgcgg tgcagccgct gcatttcgcg caatacggct
    23461 gggtcggtgc gatgggcggc gtgctgcgcg tgctgcattt cctgatggga ctcgcggcgt
    23521 gcgcgctctg cgcgacgggg ctgcatctgt ggatcgagcg gcggcgggcg cagcacgacc
    23581 gctcggcgaa cgtgctggcc gcggtcgccg tcggcgcctg cggcgggctg gtgctggcgg
    23641 gcggcgtcct gctgctcgcg gggcgtgcgt tgcccgccgg cgtgcacgtc gaccatgtgc
    23701 tcgcgatgct gttctgggcc gtgtggggtg gcgcgctcgc gctcgcggcc tgcgttgccg
    23761 atcgcgcggc ctggctgcgc acgctgatgc gtgcggccgg cgccgcttac gggctggcag
    23821 gggcgacgca ttgcgcgatc gcgctgctcg gcgcgggcga acccgtgtac tggccgatcg
    23881 acgcggccct cgtcgcgttc ggtgcattgc tgctgcgtgc cgcgcgccgt ccgcgcctcg
    23941 atgcgatacg gcccgcgcgt gtgccggccg gcgccgaacc tttttaattt catgcaactg
    24001 gagacttcga tgcgcgatct gctcgaacat cgccgcctgg tcatcacgat cacgctgctt
    24061 tacctgtcac agggaatccc gatcggcatc gcgatggatg cgatgccgac cctgctgcgc
    24121 cacgacggcg caccgcttca tgcactggcg ttcctgccgc tcgtcggttt gccgtgggtc
    24181 gtgaagttcc tgtgggcgcc cgtcgtcgac aaccgctggt cgccgcgcat cggccggcgg
    24241 cgcagctgga tgctgccgat gcagacgctc gtggtgctct gcctcggcag cctcgcgcag
    24301 atcgggatga cggtcgcgac ggccggatgg gcggtcggcc tgctggccgt cgcgtcgctt
    24361 gcgagcgcga cccaggacat cgcgaacgac gggatggccg ccgagcactt cagcggcgac
    24421 acgctcgcga agatcaacgc gatccagatc gcgggcgtga tgatcggctt cttcggcggc
    24481 ggcgccggca cgttgacgct gatcggcctg ttcggccagc gggccgcgtt tctcgcgctg
    24541 gcggccgtgc cgctcgcgag cctggtttgc gtgctgtggg tgttgccgcg cgatgcggat
    24601 cgtgcgcgcg cgaagcccga gcatgatgcg agcctcgtcc gtttcgcgaa gcggccgcgc
    24661 tcgtggtcgc tgctgtcgct tgcgctgctg tcggcgatga cggccgtatc gggtttcggc
    24721 ctgtcgaagc tgttcctcaa cgacgcgggc tggacgctcg acgcgatcgg caagctcggc
    24781 atggccggcg gcatcgtgac ggtcgtgctc ggttgcggcg gcggtgcgtg gctcgtgagg
    24841 cggctcgggt tgtggcgtgc gttcacggcc ggcgtgagct gtgcgggcgc ggccgcgctg
    24901 ctgtggttcg cgcaggcggg cgggtggctg ccggtgtcgc cgtcgtgggc atggctgtgc
    24961 acggtactcg gttcgctggc gaccgggatc acgtcggtgt cgatcatgac ggccggcatg
    25021 cgcttcgcgg gcggcagcga ccaggccggc accgacgtca cggccgtgca gagtacgcgc
    25081 gacctcggcg agctgatcgc gtcgtcgacg attctgtcgc tcaccgcgaa ggtcggttat
    25141 acgggcgggt ttctcacggg cgccgcgctg gcggtgctcg cggcgctgat cgcgatgcgg
    25201 ctgaagcggc gcgagtcggc gtatgcggtg aagggggatg atgcgctggc gtga
//
