BGC0002679 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002679 (Chromobacterium violaceum ATCC 12472)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS-like	1	14,156	chromobactin	NRPS:Type I	100%

BGC0002679 - Region 1 - NRPS-like

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Location: 1 - 14,156 nt. (total: 14,156 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 14,157
Label		BGC0002679

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002679	1.00	NRP	chromobactin	Chromobacterium violaceum ATCC 12472
BGC0000343	0.41	NRP	enterobactin	Pseudomonas sp. J465
BGC0002474	0.30	NRP	agrobactin	Agrobacterium tumefaciens
BGC0002493	0.30	NRP	parabactin	Paracoccus denitrificans PD1222
BGC0001185	0.28	NRP	bacillibactin	Bacillus velezensis FZB42
BGC0001925	0.24	Alkaloid	altemicidin, SB-203207, SB-203208	Streptomyces sp.
BGC0002476	0.24	NRP	enterobactin	Escherichia coli str. K-12 substr. MG1655
BGC0000401	0.23	NRP	paenibactin	Paenibacillus elgii B69
BGC0002017	0.21	NRP	potensibactin	Nocardiopsis potens DSM 45234
BGC0002324	0.20	NRP, Polyketide	myxochelin B, myxochelin N, myxochelin O, myxochelin P, myxochelin Q, myxochelin A	Archangium violaceum

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002679	1.00	NRP	chromobactin	Chromobacterium violaceum ATCC 12472
BGC0000343	0.73	NRP	enterobactin	Pseudomonas sp. J465
BGC0002474	0.64	NRP	agrobactin	Agrobacterium tumefaciens
BGC0002493	0.63	NRP	parabactin	Paracoccus denitrificans PD1222
BGC0001185	0.62	NRP	bacillibactin	Bacillus velezensis FZB42
BGC0001925	0.58	Alkaloid	altemicidin, SB-203207, SB-203208	Streptomyces sp.
BGC0002476	0.57	NRP	enterobactin	Escherichia coli str. K-12 substr. MG1655
BGC0000401	0.56	NRP	paenibactin	Paenibacillus elgii B69
BGC0002017	0.53	NRP	potensibactin	Nocardiopsis potens DSM 45234
BGC0002324	0.52	NRP, Polyketide	myxochelin B, myxochelin N, myxochelin O, myxochelin P, myxochelin Q, myxochelin A	Archangium violaceum

Similar known gene clusters from MIBiG 4.0

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 14156:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

CV_1484

AMP-binding (31..435): X

nrpys: diOH-Bz, Sal, diOH-Bz

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
Large clusters prediction:: Hydroxy-benzoic acid derivates (diOH-Bz, Sal)
Small clusters prediction:: Hydroxy-benzoic acid derivates (diOH-Bz, Sal)
Single AA prediction:: dhb (diOH-Bz)

Stachelhaus prediction details:

Stachelhaus sequence:: PLPAQGVVNK
Nearest Stachelhaus code(s):: diOH-Bz or Sal PLPAQGVVNK (97% 8Å match); diOH-Bz PLPAQGVVNK (97% 8Å match)
Stachelhaus code match:: 100% (strong)

CV_1486

AMP-binding (239..635): X

nrpys: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAEDIGSIIK
Nearest Stachelhaus code(s):: Lys DAEDIGSVIK (82% 8Å match)
Stachelhaus code match:: 90% (moderate)