BGC0002680 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002680 (Chromobacterium violaceum ATCC 12472)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	24,793	viobactin	NRPS:Type I	100%

BGC0002680 - Region 1 - NRPS

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Location: 1 - 24,793 nt. (total: 24,793 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 24,794
Label		BGC0002680

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002680	1.00	NRP	viobactin	Chromobacterium violaceum ATCC 12472
BGC0002415	0.39	NRP	vanchrobactin, trivanchrobactin, divanchrobactin	Vibrio campbellii
BGC0002075	0.32	NRP, Alkaloid	pyreudione A, pyreudione B, pyreudione C, pyreudione D, pyreudione E	Pseudomonas fluorescens
BGC0002476	0.28	NRP	enterobactin	Escherichia coli str. K-12 substr. MG1655
BGC0002359	0.28	NRP	dudomycin A	Streptomyces albus subsp. chlorinus
BGC0001825	0.26	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0001824	0.25	NRP	xefoampeptides A-G	Xenorhabdus beddingii
BGC0001833	0.24	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0002414	0.24	NRP	trichrysobactin, cyclic trichrysobactin, chrysobactin, dichrysobactin	Dickeya chrysanthemi
BGC0002413	0.24	NRP	frederiksenibactin	Yersinia frederiksenii ATCC 33641

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002680	1.00	NRP	viobactin	Chromobacterium violaceum ATCC 12472
BGC0002415	0.71	NRP	vanchrobactin, trivanchrobactin, divanchrobactin	Vibrio campbellii
BGC0002075	0.65	NRP, Alkaloid	pyreudione A, pyreudione B, pyreudione C, pyreudione D, pyreudione E	Pseudomonas fluorescens
BGC0002476	0.61	NRP	enterobactin	Escherichia coli str. K-12 substr. MG1655
BGC0002359	0.61	NRP	dudomycin A	Streptomyces albus subsp. chlorinus
BGC0001825	0.60	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0001824	0.59	NRP	xefoampeptides A-G	Xenorhabdus beddingii
BGC0001833	0.58	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0002414	0.58	NRP	trichrysobactin, cyclic trichrysobactin, chrysobactin, dichrysobactin	Dickeya chrysanthemi
BGC0002413	0.57	NRP	frederiksenibactin	Yersinia frederiksenii ATCC 33641

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 24793:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-X - Ser)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

CV_2233

Search NORINE for peptide: strict or relaxed

AMP-binding (499..903): X

nrpys: Orn, Lys, Arg

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Long positively charged side chain (Orn, Lys, Arg)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DGEDMGFISK
Nearest Stachelhaus code(s):: Orn DTEDMGFVDK (59% 8Å match)
Stachelhaus code match:: 70% (weak)

AMP-binding (2017..2416): Ser

nrpys: Ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Aliphatic chain or phenyl group with -OH (Ser, Thr, Dhpg, Hpg)
Small clusters prediction:: ser (Ser)
Single AA prediction:: ser (Ser)

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHFSLVDK
Nearest Stachelhaus code(s):: Ser DVWHFSLVDK (97% 8Å match)
Stachelhaus code match:: 100% (strong)