LOCUS       BGC0002681              8322 bp    DNA     linear   BCT 27-FEB-2015
DEFINITION  Francisella tularensis subsp. tularensis SCHU S4 complete genome.
ACCESSION   BGC0002681
VERSION     BGC0002681
KEYWORDS    .
SOURCE      Francisella tularensis subsp. tularensis SCHU S4
  ORGANISM  Francisella tularensis subsp. tularensis SCHU S4
            Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
            Francisellaceae; Francisella.
COMMENT     On Jun 18, 2009 this sequence version replaced AJ749949.1.
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 18:12:42
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..345)
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:FTT_0024c"
                     /db_xref="EnsemblGenomes-Tr:CAG44657"
                     /db_xref="UniProtKB/TrEMBL:Q5NIP2"
                     /locus_tag="FTT_0024c"
                     /note="ORF ftt0024c"
                     /product="hypothetical protein"
                     /protein_id="CAG44657.1"
                     /transl_table=11
                     /translation="MENSLLISNFKQWLFLILLSSISISSICYSNARSEIIIENNCSVP
                     IFLNVAPGNSTGKKIDNQKLLANEYINLGQYTNDKIFNNTSIININYHSENLQNNGSIQ
                     FSLKKWLEIK"
     protocluster    1..8322
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[5727:7647]"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5728..7647
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
     cand_cluster    1..8322
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="NI-siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..8322
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002681"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..8322
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NI-siderophore"
                     /region_number="1"
                     /rules="IucA_IucC"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(1..345)
                     /locus_tag="FTT_0024c"
     gene            complement(393..1922)
                     /locus_tag="FTT_0025c"
     CDS             complement(393..1922)
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:FTT_0025c"
                     /db_xref="EnsemblGenomes-Tr:CAG44658"
                     /db_xref="InterPro:IPR021956"
                     /db_xref="UniProtKB/TrEMBL:Q5NIP1"
                     /locus_tag="FTT_0025c"
                     /note="ORF ftt0025c"
                     /product="hypothetical membrane protein"
                     /protein_id="CAG44658.1"
                     /transl_table=11
                     /translation="MLNKINIVFICFLVLSITPFMGFSNSFKNSNEQSQKSNSIDKQGI
                     TQLQSQIANIQAEINHLTQIKNSNNSAQFATYSSKVENIGLPNSLPDNNKLTLDIMTNI
                     DSDSSIINLSDCSIGGIFDKDGGINVGGAPAITTQGEVTFLGAYSGNNTVPIGMISSNL
                     FASTVMGLRNKFDSYSIFFGGKIEADAQLWFGSSTISNKATNLASNGQNISLTAANLYF
                     LSNVGHYVTAEIEFNTTELNNFSLGNAFVIFGNLDTSPFFLTAGRNKLSVGAFGGGGPW
                     TGGITKNFLSPGKVTNVSLNYKSDVWNANVAVFGSNDNQFNFSTGLFYAQKWTQDIAVG
                     FNTGYVYNMAGAGNPSLSRFLQSQGHPTDTIGSFNVNTNITYTIAGGFLNLGAGWATTT
                     NKKDFTGSGKDVLAGAWYAAANYSLVFRGRKTNFGISYGKSYNSTNIPMTLTASPLNFG
                     RSSSGIQKQIIVSSQRAYFDNNVLFGPEYSYQQLYNGKHMNTITIDMAVYL"
     gene            complement(2007..3197)
                     /locus_tag="FTT_0026c"
     CDS             complement(2007..3197)
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:FTT_0026c"
                     /db_xref="EnsemblGenomes-Tr:CAG44659"
                     /db_xref="GOA:Q5NIP0"
                     /db_xref="InterPro:IPR001958"
                     /db_xref="InterPro:IPR004812"
                     /db_xref="InterPro:IPR011701"
                     /db_xref="InterPro:IPR016196"
                     /db_xref="InterPro:IPR020846"
                     /db_xref="UniProtKB/TrEMBL:Q5NIP0"
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 84.2; E-value:
                     1.1e-25)"
                     /gene_kind="transport"
                     /locus_tag="FTT_0026c"
                     /note="Similar to Q9HWP5 Probable MFS transporter from
                     Pseudomonas aeruginosa (402 aa). FASTA: opt: 568 Z-score:
                     586.0 E(): 9.5e-25 Smith-Waterman score: 568; 26.425
                     identity in 386 aa overlap ORF ftt0026c"
                     /product="conserved membrane protein"
                     /protein_id="CAG44659.1"
                     /transl_table=11
                     /translation="MQIDNKNLKYIPLLVLLTWFLGNMGVHFLLPLLPLLSNNLDASVK
                     LTQYVIAFFLAGKALGMIVYGPLSEIYGRRKFMLFGLILYMSSSLLCMLTTDIYWLIFW
                     RFVQGLGVSGTILMGRVIINDSYPNDKAANIFGYLFALAAVIIACLPTLGGIIAIFKNW
                     QLAFATMMIYSSLIFVIMLKFLPETQSEQFQKSFSLIGIIKDYSNILRNRVFLGYLMCT
                     SLMVAGESAFNTNAAFLMIKTYGVSPKIFGMMMSSLLIAHLLGAAICGRYVVKRGISKL
                     TGVGALILVLAAMFLSVTSILKFDGPYLTITAMFIYFLGTGFIMTTAAVGVVSPFPKMI
                     GTAMAFALSLEFLLSALSSFITSHLSISSLFPITVLITLLSLGSFAMWFFCIKRDK"
     gene            complement(3213..4466)
                     /gene="lysA1"
                     /locus_tag="FTT_0027c"
     CDS             complement(3213..4466)
                     /EC_number="4.1.1.20"
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:FTT_0027c"
                     /db_xref="EnsemblGenomes-Tr:CAG44660"
                     /db_xref="GOA:Q5NIN9"
                     /db_xref="InterPro:IPR000183"
                     /db_xref="InterPro:IPR009006"
                     /db_xref="InterPro:IPR022643"
                     /db_xref="InterPro:IPR022644"
                     /db_xref="InterPro:IPR029066"
                     /db_xref="UniProtKB/TrEMBL:Q5NIN9"
                     /gene="lysA1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_Arg_deC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_DAP_Arg_deC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1264:diaminopimelate decarboxylase (Score: 198.1;
                     E-value: 2.7e-60)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="FTT_0027c"
                     /note="Similar to DCDA_BACSU (P23630) Diaminopimelate
                     decarboxylase from Bacillus subtilis (441 aa). FASTA: opt:
                     437 Z-score: 538.0 E(): 4.5e-22 Smith-Waterman score: 437;
                     27.295 identity in 414 aa overlap"
                     /product="diaminopimelate decarboxylase"
                     /protein_id="CAG44660.1"
                     /sec_met_domain="Orn_Arg_deC_N (E-value: 8.7e-36, bitscore:
                     112.4, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 3.4e-12,
                     bitscore: 35.5, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKLSDSKSVFSKLSNKQIETIIQRYASPCFIIDENALLERARLF
                     QQAILNQYQNSIAAYSVKTQSLNTIIQKFYEVGFIPEVVSSDEFEQIQKLQLCDKSIIF
                     NGPYKNDASLIKALQLNAMINCDHFDEILRIAKIAKKLNITAKIGLRVADNKTPQNWSR
                     FGFALTDQQSNSDIFTTIDKIQQIANIQLAGLHCHIGTNIRDISRFTAMAKNIAELAET
                     ILTKYKLTLEWIDLGGGLAGISPTLSDKRLQPYNPFDLELYAATIIAPLKEYLNKTNDK
                     TKLIFELGRSLVDYSVALLTTIVGTREQNEDFQSLITDAGIHTIPTISTYRHPIYHLKT
                     DSYHKKTLLLGPSCMQHDFLHDDIFLPKLEYGDKLLIDGVGAYNISRNNEFIHLKPSVI
                     LIDKNHQYQVLRVRQTHQ"
     gene            complement(4459..5721)
                     /locus_tag="FTT_0028c"
     CDS             complement(4459..5721)
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:FTT_0028c"
                     /db_xref="EnsemblGenomes-Tr:CAG44661"
                     /db_xref="GOA:Q5NIN8"
                     /db_xref="InterPro:IPR011701"
                     /db_xref="InterPro:IPR016196"
                     /db_xref="InterPro:IPR020846"
                     /db_xref="UniProtKB/TrEMBL:Q5NIN8"
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 73.9; E-value:
                     1.4e-22)"
                     /gene_kind="transport"
                     /locus_tag="FTT_0028c"
                     /note="Similar to YCEE_ECOLI (P25744) Hypothetical
                     transport protein yce from E. coli (408 aa). FASTA: opt:
                     364 Z-score: 408.7 E(): 7.1e-15 Smith-Waterman score: 450;
                     26.582 identity in 395 aa overlap ORF ftt0028c"
                     /product="conserved membrane protein"
                     /protein_id="CAG44661.1"
                     /transl_table=11
                     /translation="MNNHIKAQILLLCFCQLIIIAAMEMSNPFLPIYLQSLGDFDLLPV
                     NAWNVLAYAMPLISAMLFSPFWGKYADRFGYKTMILRAALALAIIQLLIYLTNSALLFI
                     TLRFIQGAIAGFLLAAQSYAVVIVSKEFRSRILAWLQSSTAIGIAIGPLIGGVLATLLS
                     YNQIFLICAVIACCIFIILLIKLESISNPSLLSKQDNNKNCYHKNTSNNYLIYVYFSVI
                     FLAILLSQTAKFLPQSFFAIYAKEFFSSDPIIIAAIYAAPAFSLLLFSAPIGYLFDKLL
                     NKQVNNQYFFASSYFIILFAISTVAIYVHGFTHNIYLILAARFILGVTFAGTLPCLFSL
                     ACRTKDNNFGFLIGYCNTFSKFGNLCGIFLGGFIFQISSMQTVFYVTAIIYMFLVVIYI
                     CLLYLFDLKSSNFKNKELINV"
     gene            complement(5728..7647)
                     /locus_tag="FTT_0029c"
     CDS             complement(5728..7647)
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:FTT_0029c"
                     /db_xref="EnsemblGenomes-Tr:CAG44662"
                     /db_xref="GOA:Q5NIN7"
                     /db_xref="InterPro:IPR007310"
                     /db_xref="InterPro:IPR022770"
                     /db_xref="UniProtKB/TrEMBL:Q5NIN7"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /locus_tag="FTT_0029c"
                     /note="Similar to AAO89973 (Q83EA5) FrgA protein from
                     Coxiella burnetii (528 aa). FASTA: opt: 1047 Z-score:
                     1237.4 E(): 4.9e-61 Smith-Waterman score: 1053; 34.051
                     identity in 511 aa overlap ORF ftt0029c"
                     /product="conserved hypothetical protein"
                     /protein_id="CAG44662.1"
                     /sec_met_domain="IucA_IucC (E-value: 3e-61, bitscore:
                     195.9, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHIEQLQKNKTPLNIETLELIGLITADLNPTISSIKASTLKNQFK
                     RVALSFYREGLLGKSKKINDTLFFYNINNDKILKINNPILKSLNRIELPDQLTIQDCLT
                     KRETSLENIEELINWAKDNNPQINHDDWQQFEYELDNSFENELSMNIYRGLRQKQLANT
                     INSANYLNLWQWLTTTMSKNQQLAFLEQWGAVGHIYHPSSKTKIGLSKFENILYSPEFE
                     NEVNIIFGAIHKNIAHIEIIDNRIDNYQNWMIINYPEQYKIWYHELDNRGLDSNNYLMI
                     PIHPWQAEHILPAKHKCLIDCQQLIIINDCKYTTKPSMSFRTMLPVATKDKTLMPHIKL
                     PVAIHATSVTRTVSPESVKTGPRISKILLEILAKENHLAKNMDILADIAGIHTTKACRK
                     DDIRQLSAIFRTNPEELLDSDEVACPLASLFVKTPQNQALICDILELLDYNQPSQILAY
                     FRKYTQITLTACLDLYLLYGIALEAHQQNTLVVFKENMPQKLLIRDLGGMRLHLPSFEA
                     SGFHFPKDTFSLTFTNSQTITRRKFIHACLQSNIGELVIQLSSHYKIAEGRFWTIVKGE
                     IHQRFEYLKPRISPDKYKQEYTQILEKPWSIKALTRMRLNDKLECDKDDMQGDIYINLK
                     NPLA"
     gene            complement(7900..8322)
                     /gene="fur"
                     /locus_tag="FTT_0030c"
     CDS             complement(7900..8322)
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:FTT_0030c"
                     /db_xref="EnsemblGenomes-Tr:CAG44663"
                     /db_xref="GOA:Q5NIN6"
                     /db_xref="InterPro:IPR002481"
                     /db_xref="InterPro:IPR011991"
                     /db_xref="UniProtKB/TrEMBL:Q5NIN6"
                     /gene="fur"
                     /gene_functions="regulatory (smcogs) SMCOG1266:hydrogen
                     peroxide sensitive repressor (Score: 122.8; E-value:
                     1.6e-37)"
                     /gene_kind="regulatory"
                     /locus_tag="FTT_0030c"
                     /note="Similar to FUR_ECOLI (P06975) Ferric uptake
                     regulation protein from E. coli (148 aa). FASTA: opt: 396
                     Z-score: 515.7 E(): 7.8e-21 Smith-Waterman score: 396;
                     40.714 identity in 140 aa overlap"
                     /product="ferric uptake regulation protein"
                     /protein_id="CAG44663.1"
                     /transl_table=11
                     /translation="MNSKNLDLKEFGFKVTQPRVEILKLFEKNKDKHLSPDDVFSKLKA
                     QGSTTGIATVYRVLNQFESAGIINRLKLDNEQVMYELNQGEHHDHIICVKCNMIQEFYS
                     PGIEALQKQIVESFGAEMIDYSLNIYVKCKSCREKI"
ORIGIN
        1 ttatttgatt tccagccatt tttttaaact gaattgtatc gaaccattat tctgtaaatt
       61 ttccgaatga taattgatat ttattatcga tgtattatta aagattttat catttgtata
      121 ctggccgagg ttaatatatt cattagcaag taacttttga ttgtctatct ttttaccggt
      181 gctattacca ggagcaacat ttaaaaaaat tggtactgag cagttatttt ctataatgat
      241 ttcagatctg gcattgctgt agcaaatact acttatagag atactcgata acaagattaa
      301 aaataaccat tgtttaaagt tactgattaa taaactattt tccatttaag cctctatatt
      361 attgttaaat atacagaaat aaataataat acttaaagat atacagccat atctattgta
      421 atagtattca tatgtttacc attatatagt tgttggtatg agtattctgg tccaaaaagt
      481 acattattat caaaatatgc gcgttgtgag gaaactataa tctgtttttg tatccctgat
      541 gatgatctcc caaagttaag tggtgaagcg gttaatgtca tggggatatt tgttgaatta
      601 taagatttac catatgatat tccaaagttg gtttttctac ctctaaaaac aagtgaatag
      661 ttagcggcag cataccatgc accagctaaa acatctttac cagagcctgt gaagtctttt
      721 ttattggttg ttgttgccca cccagcacct aaatttaaga aaccaccagc aatagtatag
      781 gtaatatttg tattgacatt aaaactacca atggtatcgg taggatgccc ctgactctgt
      841 aagaacctac ttaaagaggg attgccagct cctgccatat tataaacata accagtatta
      901 aaaccgacag ctatatcttg ggtccatttt tgtgcataaa ataatccagt tgaaaaatta
      961 aactggttat cgttagagcc aaaaacagcg acattagcat tccatacatc gcttttatag
     1021 tttagtgaaa catttgtcac tttaccagga gagaggaagt tttttgttat tccacctgtc
     1081 catggaccac ctccaccaaa cgcacctaca gagagtttgt ttcttccagc agttaagaaa
     1141 aaaggtgaag tatcaaggtt gccaaagatg acaaaagcgt tacccaaaga gaaattatta
     1201 agttcagtag tgttaaattc tatttctgca gttacataat gtccaacatt tgataaaaag
     1261 tataagtttg ctgcggttag tgatatattt tgaccattac tagcaaggtt tgttgcttta
     1321 tttgagatag tactactacc aaaccaaagc tgcgcatcag cttcaatttt accgccaaag
     1381 aatatcgaat aactatcaaa cttattcctt aaccccatta cagttgaggc aaataagtta
     1441 cttgatatca ttcctatagg tacagtattg ttaccagagt atgctcctaa gaaggtaacc
     1501 tcaccttggg ttgtaatagc aggtgcacca ccaacgttta taccaccatc tttgtcaaag
     1561 ataccaccaa tagagcaatc acttagattt atgatagaac tatcagaatc tatatttgtc
     1621 attatatcaa gagttaattt attattatca ggtaagctat taggtagacc aatgttttcg
     1681 acttttgaac tgtatgtagc aaattgtgct gaattatttg agttttttat ttgggttaaa
     1741 tgatttattt cagcttgaat atttgctatt tgtgattgta gttgggttat accttgctta
     1801 tcaattgagt ttgatttttg cgattgttca ttagagtttt taaaactgtt agaaaacccc
     1861 ataaaggggg taattgataa tactaaaaag catataaata ctatattaat tttatttagc
     1921 atattaagaa agaaacaaag aatataaatt aatttttaga tattaaatta aatgataata
     1981 ataatcaata ctatttggaa aaaatattat ttatctcttt taatacagaa aaaccacatt
     2041 gcaaaagagc ctagacttag taaagttata agtacagtaa taggaaataa agaagaaatt
     2101 gataagtgac tagtaataaa actgcttaat gctgataata aaaattctaa tgatagtgca
     2161 aaagccatgg ccgtaccaat cattttagga aatggtgata ctacgccaac tgccgctgtt
     2221 gtcatgataa aacctgttcc taagaaataa atgaacatcg ctgttatggt aaggtatgga
     2281 ccatcaaatt taagtataga tgttactgat aggaacattg ctgctaatac taatattagc
     2341 gcaccaactc ctgttagttt tgaaatacct cttttgacca catagcgacc acatatggcg
     2401 gctccaagta ggtgagctat taacaagcta gacatcatca tgccaaaaat ttttggtgag
     2461 actccgtaag tttttatcat caagaaagca gcatttgtgt taaatgctga ttcaccagct
     2521 accattaggc ttgtacacat cagataaccc aaaaatacgc ggttacgtaa gatattagaa
     2581 taatccttaa taatccctat tagagaaaat gatttttgga attgctcaga ctgtgtttct
     2641 ggtaaaaatt ttagcattat cacaaatatt aaactgctat aaatcatcat ggtagcaaaa
     2701 gctagttgcc aatttttgaa tatggctatt attcctccta aagtaggcaa acaagcaata
     2761 attactgcag ctagggcaaa caagtagcca aaaatattag cagctttatc atttggatat
     2821 gagtcattaa taataaccct acccataagt atagtaccac ttacaccgag tccttgaaca
     2881 aaacgccaaa agattaacca gtatatatct gttgttagca tacataacag actacttgac
     2941 atatataata ttagaccaaa aagcataaat ttacggcgac catagatttc agatagtggc
     3001 ccatagacta tcattcctag agccttacca gctaagaaga aagctattac atactgagtt
     3061 agttttacag atgcatcgag gttgtttgag agtaaaggta gtaatggcag caagaaatgt
     3121 acgcccatat tacctaaaaa ccatgttaaa agaacaagta aagggatata ttttaaattt
     3181 ttattatcaa tctgcatttt aattacctat tattattgat gtgtttgtct aactctgaga
     3241 acttggtatt gatgattttt gtcgattaga attacacttg gctttagatg gatgaactcg
     3301 ttatttcttg atatgttata agccccaact ccatctatca gtaatttatc tccatattca
     3361 agcttcggta aaaatatatc atcatgcaaa aaatcatgtt gcatacaact aggacccaat
     3421 agtaaggttt tcttgtggta gctatcagtt tttaggtggt agattgggtg tctataggta
     3481 gatattgttg gtatggtatg tatcccagca tctgttatta agctttggaa atcttcattt
     3541 tgctctctag taccaactat agttgttaat agtgctactg aataatcgac caaactacgt
     3601 cctagctcaa aaattaattt agttttatca ttggttttgt ttaaatactc ttttaggggg
     3661 gctattattg tcgcggcata tagttctaaa tcaaaagggt tgtatggttg taatctttta
     3721 tcgcttagag tagggcttat tcccgctaaa ccgccaccta agtctatcca ttctagagta
     3781 agtttatact ttgttagaat cgtctcggcc aattcggcaa tgttttttgc cattgcggta
     3841 aatctcgaga tatctctaat atttgttcca atatgacaat gtagcccagc taattgaata
     3901 tttgctattt gttgtatttt gtctatggtg gtaaatatat cactattact ttgttggtct
     3961 gttaaggcaa atccaaatct agaccaattt tgaggagttt tattatctgc tactcttaaa
     4021 ccaatttttg cagttatatt tagctttttt gcgatctttg caatgcgcaa tatttcatca
     4081 aagtgatcac agtttatcat agcatttaat tgtaatgctt tgattaagct tgcatcattt
     4141 ttatatggac cattaaagat tatactttta tcacatagtt gtagtttttg tatttgctca
     4201 aactcatcac tcgagacaac ctctgggata aatcctactt cataaaattt ttgaataata
     4261 gtgtttagag attgagtttt tactgagtat gcggcaatac tattttgata ttgatttaaa
     4321 atagcttgtt gaaaaagtct agctcgttct agcagcgcat tttcatcgat gataaagcat
     4381 ggcgaagcat atctttgaat aattgtttca atttgtttgt ttgaaagttt actaaaaaca
     4441 ctctttgaat cgcttagttt agacatttat taattcctta tttttaaaat tagatgattt
     4501 aaggtcaaat agataaagta gacatatgta gataactact aaaaacatat agataatagc
     4561 agtaacatag aaaactgttt gcatgcttga tatttggaat ataaatccac ccaggaaaat
     4621 gccacagaga tttccaaatt tagagaacgt attacagtag ccaattagaa aaccaaaatt
     4681 attatcttta gttctacatg ctaagctaaa taagcatggt agtgtgccgg caaaggtaac
     4741 tccaagtatg aatctagctg ctaatataag ataaatgttg tgtgtaaatc catgaacata
     4801 aattgctaca gtggatattg caaacaaaat tataaaatag ctactggcaa agaaatattg
     4861 attattaact tgtttgttaa ggagcttatc aaataaataa cctatcggcg ctgaaaatag
     4921 cagtagacta aatgcaggtg ctgcataaat ggctgctatg attatcgggt ctgagctaaa
     4981 aaactcttta gcataaatgg caaaaaatga ttgtggcaaa aattttgccg tttgagataa
     5041 taaaatagct aagaaaatta ccgagaaata aacatatatt aaatagttat tagaagtatt
     5101 tttatgatag caatttttat tattatcttg ttttgataat aaagaagggt ttgagatact
     5161 ttctaattta atcagtaaga tgataaagat acagcaagct ataacagcac aaatcaaaaa
     5221 tatttggtta taactaagta atgtggctaa aacaccacct atcaaaggac ctatagcgat
     5281 accgattgcc gtagatgatt gtaaccaggc aagtatacga cttctaaatt cttttgaaac
     5341 aataactaca gcatagcttt gagctgctaa taaaaatcca gctatagctc cttggataaa
     5401 tcttagggtt ataaatagca aagcactatt tgttagatat atcagcaatt gtataatagc
     5461 taaagctaag gcagctctaa ggatcattgt tttatagcca aatctatcgg catatttacc
     5521 ccaaaaagga gagaaaagca ttgctgatat taaaggcatt gcataagcta agacattcca
     5581 ggcatttact ggtagtagat caaaatcgcc gagggattgt aagtaaattg gtaaaaaagg
     5641 attactcatt tccatagctg ctatgattat aagctgacaa aagcatagta acagtatttg
     5701 tgcttttata tgattattca tgatttttta agctaatgga tttttgaggt tgatatagat
     5761 atctccttgc atgtcatctt tatcgcactc tagtttgtca tttaaacgca ttctagtaag
     5821 tgctttgatt gaccaaggtt tttctaatat ttgagtatat tcttgtttat atttatcagg
     5881 actaattcgt ggttttaaat actcaaatct ttggtgtatt tcacctttta cgatagtcca
     5941 gaaacgcccc tcagcaattt tataatgact acttagctgt attactagtt caccaatatt
     6001 actttgtaag catgcatgta taaatttacg cctagtaatt gtttgagaat tagtaaatgt
     6061 tagcgagaat gtatctttag gaaagtgaaa tccgcttgct tcaaagcttg gtaagtgtag
     6121 cctcattcct cctaggtctc ggattagtaa tttttgtggc atattttctt tgaaaactac
     6181 aagtgtgttt tgctgatgag cttctaaagc tataccatag agtaggtata gatctagaca
     6241 agcagttaaa gttatctgag tgtactttct aaaatatgct aaaatctgac taggttgatt
     6301 atagtctaat aactccaaaa tatcacatat gagtgcttgg ttttgtgggg ttttgacaaa
     6361 caagcttgca agtggacaag ctacttcatc cgagtctaat aactcttcag gatttgtcct
     6421 aaaaattgct gaaagttggc ggatatcatc ttttctacag gctttggtag tatggatacc
     6481 agcaatatca gctaaaatat ccatattttt agctaagtga ttctctttag caagtatttc
     6541 taatagaatc ttgctgattc gtggacctgt tttgacagac tcaggcgata ctgttcttgt
     6601 tacacttgta gcatgaattg ccactggtag ctttatatgt ggcattagtg ttttgtcttt
     6661 agtagccaca ggtagcattg ttctaaatga catacttggt ttagtagtat atttacaatc
     6721 attgataata ataagttgtt gacaatctat taagcatttg tgtttagctg ggagaatatg
     6781 ctcagcttgc catggatgaa ttggtatcat tagatagttg ttactatcaa gtcctctatt
     6841 atctagttcg tgataccaaa ttttatattg ctctggataa ttgatgatca tccaattttg
     6901 atagttatca atacgattat caattatttc aatatgcgcg atatttttat gaatagcacc
     6961 aaaaataata ttaacctcat tttcaaattc aggagagtag aggatgttct caaatttact
     7021 aagacctatt ttggtttttg aactggggtg atatatatga ccaactgctc cccattgctc
     7081 tagaaaagcg agttgttggt ttttagacat cgttgtagtt aaccattgcc aaagattcaa
     7141 gtagtttgca gaatttattg tgtttgcaag ttgtttttgc cttaatcctc tgtatatatt
     7201 catcgataat tcattttcaa aagaattatc tagttcatat tcaaattgtt gccaatcatc
     7261 gtgattaatt tgtggattat tatcttttgc ccagttgata agttcctcga tattttcaag
     7321 agatgtttct ctttttgtta gacaatcttg tatagttagt tgatctggta attctattct
     7381 gttgagactt ttaagaattg gattgtttat ttttaatatc ttgtcattgt ttatattgta
     7441 gaagaataaa gtatcattga tttttttaga tttaccaaga agcccctcac gataaaagct
     7501 taatgctact cttttaaact ggtttttaag agttgaggct ttaatgctac ttatagttgg
     7561 atttaagtca gctgtaatta agccaattaa ttcaagagtc tctatattaa gtggagtttt
     7621 gtttttttgg agttgttcaa tatgcatttt aaaatcccta catgataatg ataacgaata
     7681 tcattatcgt ttatttaagt ataaaataca attttttatt gcaaaaaata agggtctaga
     7741 gattttgtat attcaaaaat aaagttagta gaagtaagta tgaatttata agcttaaatt
     7801 tagaaacttc agaaaagctg ttgtgagatt gtatgcgctg ctttaagtat ttatttgtga
     7861 agtggttttt ttaaatactt ctggatagtg attattgcgt tatatttttt cacgacagga
     7921 tttgcattta acatatatat tgagactata gtcaatcatt tcagcaccga atgattcaac
     7981 aatctgcttt tgcagagctt cgattcctgg gctatagaac tcttgtatca tattgcactt
     8041 aacacagatt atatgatcat gatgctcacc ttgatttaac tcatacatta cttgttcatt
     8101 atcaagtttt aagcgattta ttattcctgc tgactcaaac tgattaagta ctctgtaaac
     8161 tgtagcgatt cctgttgtgc tgccttgcgc tttaagttta gaaaaaacat catcaggact
     8221 caaatgctta tctttgtttt tttcaaataa tttaagtatc tcaacacgag gttgagtaac
     8281 tttaaaaccg aattctttta agtcaaggtt tttcgagttc at
//
