LOCUS       BGC0002685             16397 bp    DNA     linear   BCT 14-JUN-2013
DEFINITION  Rothia mucilaginosa ATCC 25296 contig00011, whole genome shotgun
            sequence.
ACCESSION   BGC0002685
VERSION     BGC0002685
KEYWORDS    .
SOURCE      Rothia mucilaginosa ATCC 25296
  ORGANISM  Rothia mucilaginosa ATCC 25296
            Bacteria; Actinomycetota; Actinomycetes; Micrococcales;
            Micrococcaceae; Rothia.
COMMENT     This is a reference genome for the Human Microbiome Project.
            This project is co-owned with the Human Microbiome Project DACC.
            Genome Coverage: 28x
            Sequencing Technology: 454.
            Product names were updated in June 2013.
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 18:13:04
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16397
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1074
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1033:iron compound
                     ABC transporter, periplasmic (Score: 279.5; E-value:
                     4.4e-85)"
                     /gene_kind="transport"
                     /locus_tag="ROTMU0001_0980"
                     /note="identified by match to protein family HMM PF01497"
                     /product="periplasmic binding protein"
                     /protein_id="EET76295.1"
                     /transl_table=11
                     /translation="MSFNRTELTDAENHGASGVNRRAFFGLALASSAALALAACSSETT
                     TTTTSGGSTSGGNSGTRTIKDIDDENVEVPANPQKVIVLSEPTLDGLLALGVTPAGSVS
                     GRGQSGVPNYLADRAKGVQIIGTVAQVNYEQIGNLDPDLILVDSTGVDKRSEAFETLKK
                     IAPVVYCGYAGGDWRINFRNVANAMNMVDKGEEVIKAYESNAATLKDQLAPKYGDKTFS
                     IVRWAGNGPALILKELPAGQVLNDLGLKRPESQDRNGQGHSEPVSLENLATIDADYMFL
                     GTLGGASQQNPNAQGSAGLQGAEEALNKAKETSGFTNLKAVKDDHVILVDGSKWTSTGG
                     PLLLEGIIEDVKKALPL"
     protocluster    1..16397
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[12056:16397]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      12057..16397
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..16397
                     /SMILES="NC(CO)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..16397
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002685"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..16397
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            1..1074
                     /locus_tag="ROTMU0001_0980"
     gene            1213..3228
                     /locus_tag="ROTMU0001_0981"
     CDS             1213..3228
                     /codon_start=1
                     /locus_tag="ROTMU0001_0981"
                     /note="identified by glimmer; putative"
                     /product="hypothetical protein"
                     /protein_id="EET76296.1"
                     /transl_table=11
                     /translation="MTETRPVRTAARYGAVVALAGALITPGAALTGSTLAFADTPAATQ
                     QEAKAAVTISTEKWREGKLVLRGTGFTSTAPGRGAVFAVKFLDALPDEAHQAINPITKK
                     GGNSPANFMGTAKEDGTFEVEVSLPTPENTGLTAEQLKNKGWTVEGTSHRIQVLSGSLG
                     GTDADGNTYDRRASVSQNITLSDPAPSPAPTAEPSATAEPSATAEPTADPSATAEPTAD
                     PSATAEPTPAPTAEPTPAPTAEPTPAPSEDSKTCAPADNSFTPRLTIENPKAVQGGKLH
                     LTGDGWCNPEDKKASVIGLKIDDGKVSRNDATAVNDNHTIWAVITPDENGHIDAWIDLP
                     TRDNAAFKNDEDAAKYASGEHTLRLLTGSLREGDRSGTYGGANSQGGINTTFTIGEYAP
                     GDAPEPVNASELTNGNGVQVSRDGSTVTVTVPNAEPGTWVYAATYLGNSPQTLYGSGWK
                     RLDGNRSFSYETSVSMPAATYRVVVHNGNQGAENAVLGFADMTVERAVTPRQDVSRDEQ
                     DATDQLVEELNENPATSTSTAPVPMRNAGGRISTRATDVDASLAALSQSTAPVVNRVQA
                     KAKVQSAQKNLATNLQKTEANAKKAVKAAAGSQNSQNTQGSQNSAAGTKAQGPIVEGTE
                     LTGLTKWLVNNANNLLLSAAGLVVLAAALLLRTSKK"
     gene            4664..5668
                     /locus_tag="ROTMU0001_0983"
     CDS             4664..5668
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1011:transport
                     system permease protein (Score: 298.9; E-value: 6.6e-91)"
                     /gene_kind="transport"
                     /locus_tag="ROTMU0001_0983"
                     /note="identified by match to protein family HMM PF01032"
                     /product="iron chelate uptake ABC transporter, FeCT family,
                     permease protein"
                     /protein_id="EET76297.1"
                     /transl_table=11
                     /translation="MIQGQKLGKRLAFLFLFAVLLVGAVAASLLFGSNNLPPDQVLAVF
                     NGTASEQAQTIVMEQRIPRTLVGLAAGAALAVAGSLMQSLTRNPLAEPGLMGVNAGAAV
                     AVIGSVVVFGVMGIWQYMVAATIGGALAAVLVYTLGRGRDGSIVKLALAGVAISAALSA
                     IAQGLILADQDAYNEFRVWVAGSLEGRGMDIASTVGPVIVLGMLVAFFVAPAINALSMG
                     EEAATSLGVSVRTTQNLTLLAVTVLAGAATAAVGPIGFVGLAVPFVVRALLGNDVRWVN
                     YGSALLGPVWLLCADVLARVLVAPQETQVGIVATLAGAPVFLFLMTRRKVEAL"
     gene            5668..6774
                     /gene="fepG"
                     /locus_tag="ROTMU0001_0984"
     CDS             5668..6774
                     /codon_start=1
                     /gene="fepG"
                     /gene_functions="transport (smcogs) SMCOG1011:transport
                     system permease protein (Score: 262.5; E-value: 7.5e-80)"
                     /gene_kind="transport"
                     /locus_tag="ROTMU0001_0984"
                     /note="identified by match to protein family HMM PF01032"
                     /product="ferric enterobactin transport system permease
                     protein FepG"
                     /protein_id="EET76298.1"
                     /transl_table=11
                     /translation="MSNSSAVSTATVTTAANRSARRSGRDLGGRPVLTVRGPLSAQVPW
                     RVLILNVALVVLIAALAFWGMLQGDYKIAPEKLIPALLGEGKQITVTFAQQRAARIVAA
                     LLVGAALGLSGAIFQVISGNALGSPDIIGFTNGAATGALLQIIVFNSGPVEVALGAVVG
                     GLATSVLVWLLTRRTGLHGFRLVLVGIGVGSTLAAFNALLVVRASLTQAQTAASWLAGS
                     LNDITWERTYALLGLLLVVTPLLLMLVRPLGAIRFGDQVASGLGVSVNAYRVAALFIGV
                     LLVSLATATTGPIAFVALAAPHIAKTLSRSGGVGFTSAALMGALMVLGSDLIGRFAVPG
                     RIIQVGVVTGAIGGLYLIYLIYLERKKS"
     gene            6774..7616
                     /locus_tag="ROTMU0001_0985"
     CDS             6774..7616
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 202.8; E-value:
                     1e-61)"
                     /gene_kind="transport"
                     /locus_tag="ROTMU0001_0985"
                     /note="identified by match to protein family HMM PF00005"
                     /product="ABC transporter, ATP-binding protein"
                     /protein_id="EET76299.1"
                     /transl_table=11
                     /translation="MNASVTTRLEGENMVVAYGEHTVLNGVDFQVPEGELTVILGPNAC
                     GKSTTLKALARVNPLKDGEVRLDGTPLPQMKSRAIAKILAMLPQTPEAPSGVTVADVVA
                     RGRYPHQSLLRSWSDEDEQACVEAMQAANVLELAERPIEALSGGQRQRVWIAMTLAQQT
                     PLILLDEPTTYLDITHQIEVLNLTKKLHSEGRTVAVVLHDLNLAFRYATHVVLMKQGRI
                     IAQGDPRAIITPELIQEVFDLQSVIIPDPCTGTPLVIPKENQTIHIAADAISAARESE"
     gene            8121..9524
                     /locus_tag="ROTMU0001_0986"
     CDS             8121..9524
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1098:enterobactin/ferric enterobactin esterase (Score:
                     270.8; E-value: 3.9e-82)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ROTMU0001_0986"
                     /note="identified by match to protein family HMM PF00756"
                     /product="putative esterase"
                     /protein_id="EET76300.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 1.5e-08, bitscore:
                     23.6, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGEHEPTATVPAQSISAQNTSAQNTSEQATSAQPRTVAPTVRPAP
                     PKIPRPVPAPRVDSPLISALIAEAVSPEELNARILEVVSEGTPIIELVHREDGSISENE
                     RIVTFLYHNEQAEQVLMFINRLTDEKNLDRSLMARIEGTGWWQLSMQMETTWRASYNFL
                     PALPGERPAWLGDDDQVRLRAALDSGEGDPLNPETACNRIGRCMGVVQLEHAPVQEFIL
                     TQEEIDALPAPEWMQTSDGHQYVLGRVGDPAPDAPLFIQFDGEMWFSQGMEHTLNRAHE
                     AGRIPAMHVFFLHSGGRENRWKELNGDNPIADYLVEIAFPHLEAVHGIKTAPQNIVING
                     QSLGGLSSLLAVLSRPEAFGGAIAQSSSLWQPQVMDRLDELEAAGEIDRLRHLYLEIEV
                     GEQEWVLVPPHRELKERLEKLGLKNARCTAFNGGHDYACWRGAIVPALERIIAARREAE
                     RAERSLAEE"
     gene            9792..11492
                     /locus_tag="ROTMU0001_0987"
     CDS             9792..11492
                     /NRPS_PKS="Domain: AMP-binding (51-463). E-value: 1.9e-68.
                     Score: 222.8. Matches aSDomain:
                     nrpspksdomains_ROTMU0001_0987_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     371.2; E-value: 1.1e-112)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ROTMU0001_0987"
                     /note="identified by match to protein family HMM PF00501"
                     /product="putative (2,3-dihydroxybenzoyl)adenylate
                     synthase"
                     /protein_id="EET76301.1"
                     /sec_met_domain="AMP-binding (E-value: 8.5e-80, bitscore:
                     257.5, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVERSPLAPTPLIPESFAAKYREAGYWIDQTIPEFLLDACRAKP
                     HFPALVALSHAQLDEDGKPQQIRLSYGELEAAGRAAAARLVQAGVQPGDRVLLQLGNTA
                     EYLVYLLGIFWAAALPVFCLPQHRTTELVHFATRTDAAAHVFSSLTPGADFAALHEDVA
                     AELRKNSQEPPVAIDVAEPLTPLTEEELAEEFVPGVIQNTENLRASEQVAFLQLSGGTT
                     GISKLIPRTHAAYLYSVRGSVDICKLNNNTTMLVVLPAAHNFTMSSPGILGVMCASGKL
                     VFAADPSPQTAFHLIEMEGVTTSALVPPLAQAWVASAEKRGVSLPSLQTLQVGGSKLAP
                     AVAGKIESVLGCTVQQVFGMAEGLVNYTRSTDPIEMRLRTQGYPISPDDEILIVDDQDQ
                     PVKRGESGHLLTRGPYTIRGYYLEENANRYGFTEDGFYRTGDIVRLVAGKYLEVTGRAK
                     DQINRNGEKIAVDEIEELALTHPDVFDAVVLGIPDETVGERVGLVIVPQEGADLGENPR
                     RTMHEFFTSKKLADFKIPERVQVLQELPTTNVGKISRRELRAKLAEIFG"
     aSDomain        9945..11180
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ROTMU0001_0987_AMP-binding.1"
                     /evalue="1.90E-68"
                     /label="ROTMU0001_0987_AMP-binding.1"
                     /locus_tag="ROTMU0001_0987"
                     /protein_end="463"
                     /protein_start="51"
                     /score="222.8"
                     /specificity="substrate consensus: diOH-Bz"
                     /tool="antismash"
                     /translation="ALSHAQLDEDGKPQQIRLSYGELEAAGRAAAARLVQAGVQPGDRV
                     LLQLGNTAEYLVYLLGIFWAAALPVFCLPQHRTTELVHFATRTDAAAHVFSSLTPGADF
                     AALHEDVAAELRKNSQEPPVAIDVAEPLTPLTEEELAEEFVPGVIQNTENLRASEQVAF
                     LQLSGGTTGISKLIPRTHAAYLYSVRGSVDICKLNNNTTMLVVLPAAHNFTMSSPGILG
                     VMCASGKLVFAADPSPQTAFHLIEMEGVTTSALVPPLAQAWVASAEKRGVSLPSLQTLQ
                     VGGSKLAPAVAGKIESVLGCTVQQVFGMAEGLVNYTRSTDPIEMRLRTQGYPISPDDEI
                     LIVDDQDQPVKRGESGHLLTRGPYTIRGYYLEENANRYGFTEDGFYRTGDIVRLVAGKY
                     LEVTGRAKDQINR"
     CDS_motif       11151..11213
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ROTMU0001_0987_0001"
                     /evalue="3.20E-03"
                     /label="NRPS-A_a8"
                     /locus_tag="ROTMU0001_0987"
                     /protein_end="474"
                     /protein_start="453"
                     /score="10.4"
                     /tool="antismash"
                     /translation="TGRAKDQINRNGEKIAVDEIE"
     gene            11559..11786
                     /locus_tag="ROTMU0001_0988"
     CDS             11559..11786
                     /NRPS_PKS="Domain: PP-binding (17-70). E-value: 4.7e-11.
                     Score: 35.0. Matches aSDomain:
                     nrpspksdomains_ROTMU0001_0988_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ROTMU0001_0988"
                     /product="hypothetical protein"
                     /protein_id="EET76302.1"
                     /sec_met_domain="PP-binding (E-value: 7.6e-12, bitscore:
                     35.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAFETLRPIMEKYIVEPDSLQTAFDEPTTDLFSLGMDSMGAFAL
                     LDDLAAEGAVIEFTELVENPTVEFIASRLG"
     aSDomain        11610..11768
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ROTMU0001_0988_PP-binding.1"
                     /evalue="4.70E-11"
                     /label="ROTMU0001_0988_PP-binding.1"
                     /locus_tag="ROTMU0001_0988"
                     /protein_end="70"
                     /protein_start="17"
                     /score="35.0"
                     /tool="antismash"
                     /translation="PDSLQTAFDEPTTDLFSLGMDSMGAFALLDDLAAEGAVIEFTELV
                     ENPTVEFI"
     gene            12057..16397
                     /locus_tag="ROTMU0001_0989"
     CDS             12057..16397
                     /NRPS_PKS="Domain: Condensation_Starter (34-368). E-value:
                     2.3e-44. Score: 143.8. Matches aSDomain:
                     nrpspksdomains_ROTMU0001_0989_Condensation_Starter.1"
                     /NRPS_PKS="Domain: AMP-binding (573-996). E-value: 9.6e-92.
                     Score: 299.5. Matches aSDomain:
                     nrpspksdomains_ROTMU0001_0989_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1107-1175). E-value: 2.3e-22.
                     Score: 70.9. Matches aSDomain:
                     nrpspksdomains_ROTMU0001_0989_PCP.1"
                     /NRPS_PKS="Domain: Thioesterase (1203-1433). E-value:
                     2.3e-24. Score: 78.9. Matches aSDomain:
                     nrpspksdomains_ROTMU0001_0989_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic"
                     /locus_tag="ROTMU0001_0989"
                     /note="identified by match to protein family HMM PF00501;
                     match to protein family HMM PF00550; match to protein
                     family HMM PF00668; match to protein family HMM PF00975;
                     match to protein family HMM TIGR01733"
                     /product="AMP-binding enzyme"
                     /protein_id="EET76303.1"
                     /sec_met_domain="Condensation (E-value: 7.6e-13, bitscore:
                     37.4, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.7e-98, bitscore:
                     319.1, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.4e-18, bitscore:
                     56.5, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGVADTTAPASFGTASDLRTAANPSAQHSADSPWLPLTTNARGIY
                     FAAAIDPTNPCYNTAEVLQCPADTDLALLREAFEQLYRENEGFRVRTRIADGAASQQIL
                     TEEAFLAGIDLLVDDGELDGGELEEGELSGTAEAGEENASDLPESALPDSDLPAPVRSW
                     AQRLLAQPLATDEGVTVRSAVARYGGFLWVYHSFSHVVADGFAAFNGLSRVAAIYRALS
                     AGQPVPATRRMSLQQLLDADDAASDARDEDVAFWEASGALEQEDTSLAGRTASPSAQSV
                     RLAFSIDVPTQQALLDAAKQHAVSWPVLATAAVGSYLARVGGYPQASFGVPQMNRMFAR
                     TLPEATRALGTASAQTGCTAVNVLPVQVAATGPIAESLHSVKEQYARNAEHPLARQEDL
                     ERTARNAQSRLFGAQINMVPFDAVLPLAAPSKDESGAAVPTARIHNISAGPVADATFTL
                     RGMPGRGNSISCEIDMNPALYTAEELERHAARLREWLPAYAAEAQREGASLNNLGLATE
                     AELATLRELTAPALTEHPMEYKTLLGRFRDAVAAHPQALAVLDSAPAPGEVLTPESDRA
                     YAFDRALTYAELDERARALAVQLLDWGVCPSDAVGLRVHRGAEQYVALYALLYAGATYV
                     PVLPDLPAERVGVMMEDAECSLLLHGPGLQPLSAEELNPQEPQRHANLPQHTLPQLSIE
                     EPVQAPAAEELPGTKTGLDEDAYVLFTSGSTGRPKGVAISHRAIDNRLRWQQHQIPVGE
                     GARVLHKTPISFDVHVWELYWPLAEGAAVVIAAPEGHRDPAYLARVIAEQSVTAVHFVP
                     TMLSALTSSPAARRILADAGFGQDREQPLRYVVCSGEALQKDQVQAAGEVLGVYPLNLY
                     GPTEAAVDVTFWETSNDPQRESVPIGEPVWNTGTLILDPTGHPVPVGVTGELHLSGVQL
                     ARGYKNNPQATAAAFVEQAPAGALALLNGESQRLYRTGDLACWEILPDGRAVIGYRGRT
                     DYQIKVRGQRLELGDIEMALAAVEGVSASVALLYRGLREPALAAVLEVGDVPAERAEQL
                     VETAREHCAQVLPDYMVPTLWHTLPALPVSPSGKADRKLLASLDLTPQTSDAEGPHGLL
                     EQQLCSIIAGVLGRERFGVDEDFFASGGHSLAALEVIAAVEEQLGLSVSIGALFAHPTV
                     QALAASIAGERGEGAEFAPVLPLREQPTAHDATDAPAPLFILPPAGGLGWCYAGYLSHL
                     PAQQGVYAVQAEAFSDPQAGFASSLQELAEGYLAQIEKTLAERSLPRRFALMGWSVGGT
                     AAVQVAALAQAAGAQVERVVLLDAYPSEQWQGVPAPDEQESFRALLRMGGLPEPAADEQ
                     LDLPSTLERLQKAGSAMGYLPEEKLGVCLGSMRASAALMRGAEQAFFEGDVLLVGVPHE
                     DQPYLDAAGWSAHASSFRAVLLEGTHPDLVNPARLAEVTGHFAG"
     aSDomain        12159..13160
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ROTMU0001_0989_Condensation_Star
                     ter.1"
                     /domain_subtypes="Condensation_Starter"
                     /evalue="2.30E-44"
                     /label="ROTMU0001_0989_Condensation_Starter.1"
                     /locus_tag="ROTMU0001_0989"
                     /protein_end="368"
                     /protein_start="34"
                     /score="143.8"
                     /tool="antismash"
                     /translation="LPLTTNARGIYFAAAIDPTNPCYNTAEVLQCPADTDLALLREAFE
                     QLYRENEGFRVRTRIADGAASQQILTEEAFLAGIDLLVDDGELDGGELEEGELSGTAEA
                     GEENASDLPESALPDSDLPAPVRSWAQRLLAQPLATDEGVTVRSAVARYGGFLWVYHSF
                     SHVVADGFAAFNGLSRVAAIYRALSAGQPVPATRRMSLQQLLDADDAASDARDEDVAFW
                     EASGALEQEDTSLAGRTASPSAQSVRLAFSIDVPTQQALLDAAKQHAVSWPVLATAAVG
                     SYLARVGGYPQASFGVPQMNRMFARTLPEATRALGTASAQTGCTAVNVLPVQV"
     aSModule        12159..16355
                     /complete
                     /domains="nrpspksdomains_ROTMU0001_0989_Condensation_Starte
                     r.1"
                     /domains="nrpspksdomains_ROTMU0001_0989_AMP-binding.1"
                     /domains="nrpspksdomains_ROTMU0001_0989_PCP.1"
                     /domains="nrpspksdomains_ROTMU0001_0989_Thioesterase.1"
                     /final_module
                     /locus_tags="ROTMU0001_0989"
                     /monomer_pairings="Ser -> Ser"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       12219..12329
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ROTMU0001_0989_0001"
                     /evalue="3.00E-05"
                     /label="C2_starter_024-063"
                     /locus_tag="ROTMU0001_0989"
                     /protein_end="91"
                     /protein_start="54"
                     /score="16.7"
                     /tool="antismash"
                     /translation="PCYNTAEVLQCPADTDLALLREAFEQLYRENEGFRVR"
     CDS_motif       12651..12710
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ROTMU0001_0989_0002"
                     /evalue="3.30E-04"
                     /label="C3_starter_134-155"
                     /locus_tag="ROTMU0001_0989"
                     /protein_end="218"
                     /protein_start="198"
                     /score="13.7"
                     /tool="antismash"
                     /translation="HVVADGFAAFNGLSRVAAIY"
     aSDomain        13776..15044
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ROTMU0001_0989_AMP-binding.1"
                     /evalue="9.60E-92"
                     /label="ROTMU0001_0989_AMP-binding.1"
                     /locus_tag="ROTMU0001_0989"
                     /protein_end="996"
                     /protein_start="573"
                     /score="299.5"
                     /specificity="substrate consensus: Ser"
                     /tool="antismash"
                     /translation="DRAYAFDRALTYAELDERARALAVQLLDWGVCPSDAVGLRVHRGA
                     EQYVALYALLYAGATYVPVLPDLPAERVGVMMEDAECSLLLHGPGLQPLSAEELNPQEP
                     QRHANLPQHTLPQLSIEEPVQAPAAEELPGTKTGLDEDAYVLFTSGSTGRPKGVAISHR
                     AIDNRLRWQQHQIPVGEGARVLHKTPISFDVHVWELYWPLAEGAAVVIAAPEGHRDPAY
                     LARVIAEQSVTAVHFVPTMLSALTSSPAARRILADAGFGQDREQPLRYVVCSGEALQKD
                     QVQAAGEVLGVYPLNLYGPTEAAVDVTFWETSNDPQRESVPIGEPVWNTGTLILDPTGH
                     PVPVGVTGELHLSGVQLARGYKNNPQATAAAFVEQAPAGALALLNGESQRLYRTGDLAC
                     WEILPDGRAVIGYRGRTDYQIKVR"
     CDS_motif       14202..14261
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ROTMU0001_0989_0003"
                     /evalue="2.20E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="ROTMU0001_0989"
                     /protein_end="735"
                     /protein_start="715"
                     /score="32.3"
                     /tool="antismash"
                     /translation="AYVLFTSGSTGRPKGVAISH"
     CDS_motif       14802..14891
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ROTMU0001_0989_0004"
                     /evalue="1.60E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="ROTMU0001_0989"
                     /protein_end="945"
                     /protein_start="915"
                     /score="42.8"
                     /tool="antismash"
                     /translation="PVGVTGELHLSGVQLARGYKNNPQATAAAF"
     CDS_motif       15009..15074
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ROTMU0001_0989_0005"
                     /evalue="7.00E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="ROTMU0001_0989"
                     /protein_end="1006"
                     /protein_start="984"
                     /score="27.9"
                     /tool="antismash"
                     /translation="YRGRTDYQIKVRGQRLELGDIE"
     aSDomain        15378..15581
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ROTMU0001_0989_PCP.1"
                     /evalue="2.30E-22"
                     /label="ROTMU0001_0989_PCP.1"
                     /locus_tag="ROTMU0001_0989"
                     /protein_end="1175"
                     /protein_start="1107"
                     /score="70.9"
                     /tool="antismash"
                     /translation="EQQLCSIIAGVLGRERFGVDEDFFASGGHSLAALEVIAAVEEQLG
                     LSVSIGALFAHPTVQALAASIAG"
     aSDomain        15666..16355
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ROTMU0001_0989_Thioesterase.1"
                     /evalue="2.30E-24"
                     /label="ROTMU0001_0989_Thioesterase.1"
                     /locus_tag="ROTMU0001_0989"
                     /protein_end="1433"
                     /protein_start="1203"
                     /score="78.9"
                     /tool="antismash"
                     /translation="PLFILPPAGGLGWCYAGYLSHLPAQQGVYAVQAEAFSDPQAGFAS
                     SLQELAEGYLAQIEKTLAERSLPRRFALMGWSVGGTAAVQVAALAQAAGAQVERVVLLD
                     AYPSEQWQGVPAPDEQESFRALLRMGGLPEPAADEQLDLPSTLERLQKAGSAMGYLPEE
                     KLGVCLGSMRASAALMRGAEQAFFEGDVLLVGVPHEDQPYLDAAGWSAHASSFRAVLLE
                     GTHPDLVN"
     CDS_motif       15696..15743
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ROTMU0001_0989_0006"
                     /evalue="1.30E+01"
                     /label="NRPS-te1"
                     /locus_tag="ROTMU0001_0989"
                     /protein_end="1229"
                     /protein_start="1213"
                     /score="-1.3"
                     /tool="antismash"
                     /translation="LGWCYAGYLSHLPAQQ"
     CDS_motif       15879..15929
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ROTMU0001_0989_0007"
                     /evalue="8.40E-05"
                     /label="NRPS-te1"
                     /locus_tag="ROTMU0001_0989"
                     /protein_end="1291"
                     /protein_start="1274"
                     /score="15.1"
                     /tool="antismash"
                     /translation="ALMGWSVGGTAAVQVAA"
ORIGIN
        1 atgtctttca accgaaccga gctgaccgac gccgaaaacc acggcgcatc gggcgttaac
       61 cgccgcgcat tcttcggcct ggcgctcgcc tcctcggctg ctctcgccct cgcggcatgc
      121 agtagcgaga ccaccacgac caccacttcc ggcggttcca cctccggcgg caatagcggc
      181 acccgcacca tcaaggacat tgacgacgag aatgtagaag ttcccgccaa cccgcagaag
      241 gttatcgtcc tctctgaacc caccctcgac ggcctgctcg ccctcggcgt gacccccgcc
      301 ggttctgtct ccggccgcgg tcagtccggc gtgcccaact accttgccga ccgcgccaag
      361 ggcgtgcaga ttatcggcac cgtcgcccag gtcaactacg agcagattgg caaccttgat
      421 cccgacctga ttctggtcga ctccaccggt gtggacaagc gctccgaggc cttcgaaacc
      481 ctcaagaaga tcgcccccgt cgtctactgc ggctacgcgg gcggcgactg gcgcatcaac
      541 ttccgcaacg tcgccaacgc tatgaacatg gtcgacaagg gcgaagaagt catcaaggca
      601 tacgagtcaa acgctgctac gctgaaggac cagctcgccc ccaagtacgg cgacaagacc
      661 ttctccatcg tccgctgggc aggcaacggc cccgccctga ttctcaagga actgcccgcc
      721 ggtcaggtac tcaacgacct gggcctcaag cgccccgagt cgcaggaccg caacggccag
      781 ggccactccg agccggtctc cctggagaac ctggcaacca tcgacgcgga ctacatgttc
      841 ctgggcaccc tcggcggcgc aagccagcag aacccgaacg cgcagggctc cgcaggtctg
      901 cagggcgccg aagaagcact gaataaggcg aaggaaacct ccggcttcac caacctgaag
      961 gcagtcaagg acgaccacgt gattctcgtg gacggctcca agtggacctc caccggcggc
     1021 ccgctgctgc tcgagggcat tatcgaagac gtcaagaagg cgcttccgct ctaaacaccc
     1081 tgttctgaac gccccactct aaatacctgt gaagcaatca cccgctgaag cttccgccac
     1141 ccttcccgcc gcgatctaga cccgcggcgg gaaggggatg cacgacccac cacaccatcc
     1201 tcaaggacca caatgaccga aactcgaccc gtgcgcaccg cagcccgcta cggtgccgtc
     1261 gtggctctcg ctggcgcgct catcaccccc ggagcagcgc tgaccggctc cactctcgca
     1321 ttcgcggata ctcccgccgc cacccagcag gaagctaagg ctgccgtgac catctccact
     1381 gagaagtggc gcgaaggtaa gctcgtgctg cgcggcaccg gctttaccag caccgcaccc
     1441 ggtcgcggcg cagtgttcgc agtgaagttc ctcgacgccc tgccggatga agcgcaccag
     1501 gcgattaacc cgatcaccaa gaagggcggc aactcgcccg cgaacttcat gggaaccgcc
     1561 aaggaggacg gcacttttga ggttgaggtg tccctgccga cccccgaaaa caccggtctg
     1621 accgctgagc agctgaagaa caagggctgg accgtggagg gtaccagcca ccgtattcag
     1681 gtgctttccg gctccctggg tggtacggat gcggacggca acacctacga ccgtcgtgca
     1741 tctgtgtcgc agaatattac gctgagcgac ccggcaccga gcccggcacc gaccgcagag
     1801 cccagtgcaa ctgcagagcc ttctgcaacg gctgagccta ctgcagatcc ctctgcgacc
     1861 gctgagccta ccgctgaccc tagcgcaact gcagaaccca cccccgcacc tactgcagaa
     1921 cccaccccgg cacctaccgc agagccgacc cccgcgccca gcgaagactc gaaaacctgc
     1981 gcacccgccg ataactcctt caccccgcgc ctgaccatcg agaaccccaa ggcggttcag
     2041 ggtggcaagc tgcacctgac cggtgacggc tggtgcaacc ccgaagacaa gaaggcatcc
     2101 gttatcggtc tgaagattga cgacggcaag gtatcccgta acgacgccac cgcggtcaac
     2161 gacaaccaca ccatctgggc tgtcatcacc cccgatgaga acggccatat cgacgcctgg
     2221 attgacctgc ccacccgcga caacgcagcc ttcaagaatg acgaagacgc cgccaagtac
     2281 gcctccggtg agcacaccct gcgcctgctg accggtagcc tgcgtgaggg tgaccgatcc
     2341 ggaacctacg gcggcgccaa cagccaaggc ggcatcaaca cgaccttcac catcggtgag
     2401 tacgcccccg gtgacgcgcc cgagccggtc aacgcctccg aactgactaa cggtaatggc
     2461 gtgcaggtga gccgtgacgg ctccactgtg accgtgaccg tgccgaacgc tgaaccgggc
     2521 acctgggtgt acgccgcgac ctacctcggc aactccccgc agaccctcta cggctccggc
     2581 tggaagcgtc tggacggcaa ccgcagcttc agctacgaaa ccagtgtgag catgcccgcc
     2641 gcaacctacc gcgtggttgt gcacaacggc aaccagggcg ctgaaaatgc ggtgctcggt
     2701 tttgctgaca tgaccgtgga acgtgctgtt actcctcgtc aggacgtttc ccgcgatgag
     2761 caggacgcca ccgaccagct ggtcgaagag ctgaacgaga accccgcaac cagcacctct
     2821 accgcgccgg ttcccatgcg taacgcgggc ggccgcatca gcacccgcgc caccgacgtg
     2881 gatgcatccc tcgccgcgct ctcgcagagc accgctccgg tcgtgaaccg tgtgcaggct
     2941 aaggcgaagg ttcagagcgc gcagaagaac ctggcaacca acctgcagaa gaccgaagcc
     3001 aacgcgaaga aggcagtgaa ggctgccgcc ggttcgcaga actcgcagaa cacgcagggc
     3061 tcgcagaact ccgccgcagg cacgaaggca cagggcccga tcgttgaggg tactgagctg
     3121 accggtctga ccaagtggct ggtcaacaac gccaataacc tgctgctctc ggcggctggc
     3181 ctggtggttt tggctgcggc tctgctgctg cgcacctcca agaagtaagc tctctaacca
     3241 cacattcaca ccggcaccgg tccacgctcc acagttttga ccctgcaccc ttgaacaggg
     3301 gcgtggatcg ggtgcctcca accattcggg tcacgacccg ctgaactgca cctccatgaa
     3361 cccggtagcg ttcagcttcg accccggtaa ttttgaaagg accaccatgc gtgcaccttt
     3421 ttcgggagcc ccgaaggcat ccctgacctc taaggcgctg accgcctgcg ctgccgcaac
     3481 cctggcgctg ggcttgggcg ttggcaccgc atccgctctg cctccgggcg gtgcaaaggc
     3541 atcgactccc ggcacctcct cgaccgtttc ttcgtctgtg agcgagcacg gcgtgatttc
     3601 ctttagcgtg agcggtttcc ccgcgaacac tgtggtgtcc gtgaaggttg atgacggtaa
     3661 cctgtgcccc tccgatgcgg ctcagggcgc ttgcgtggtg caccagcaga agaccgatgg
     3721 taacggtaat gtctccggtt ccttcgttct gccggatgtt ggcgctggca cccacactct
     3781 gcgtttcctt gcaactggtg agaagcgtga caaggacggc aagtacctgg gcaccgaggc
     3841 gtacagcaac cgtagccccg agttcactgt ggtgggtgag ggcggttcgg ataattcctc
     3901 ctcgaactct tcgggttctt cctcgagccg tggctcttcc agctcaaaga gcaacggtgg
     3961 ttcctcgaat ggcggctcga actctaacaa ctcagactct gcagacgagg ctcagggctc
     4021 taacgattcc aacgagtcct cgtccaatgg tggttcgaac ggttcctcga atggttctgc
     4081 aggtggcgcg gctgaggctg agaccgtgta caccgacgct gacggcaaca ccatcaccaa
     4141 ggaggagtac gaccgcctga acgcggcagc tgactcttcc ggtacctccg gtacctccgg
     4201 cacctctggc tcttccgctg cgcctgctgc ttcggcttct gcaaatgccc agaagaaggc
     4261 gaccgcttcg gcgagcgcat cttcttcggc tgttgcgcgc ggtaccgcgt cgaacccgag
     4321 cgcttcagct tcgggcgcgg ctaacaccgc atccaccgtt caggccgtga cttacggtgc
     4381 tgcgttcccg tggattggcg tggtggttct gggcgtaagc attgtgggcg ctgctgcgct
     4441 gttgctgacc cgtaagcgct aagacttaac gtcggatgtg ggtgggggag tacccgcccg
     4501 ctccggcgtt tctctcgtta tctatcggtg tgccgggtgc ccctctggtg gggtgccggg
     4561 tgcgcctccc cgttttcttg tatcgagcat aaggagcata gtggcccgca cgagctcatt
     4621 gtcccgaggt gttcagcagg agagtacgtc ccgtcagggc tctgtgattc aggggcagaa
     4681 gctgggtaag cgcctggctt ttctgttctt gtttgcggtg cttttggtgg gggctgtggc
     4741 tgcttctttg ctgttcgggt cgaataatct tccgccggat caggttctgg ctgttttcaa
     4801 tggcactgct tctgagcagg cgcagacgat tgtgatggag cagcgtattc cgcgtaccct
     4861 ggtgggtctt gcggcgggtg cggcgttggc ggttgccggt tctctgatgc agtcgttgac
     4921 tcgtaacccg ttggctgagc ccggcctgat gggtgtgaat gccggtgctg cggtggctgt
     4981 gattggctcc gtggtggttt ttggcgtgat gggtatttgg cagtacatgg ttgctgcgac
     5041 gattggtggc gcgttggctg cggtgctggt gtacacgctg ggtcgtggcc gtgacgggtc
     5101 gatcgtgaag ctcgctctgg cgggtgtggc gatttctgcg gcgctgtcgg cgattgcgca
     5161 gggcctgatt ttggctgatc aggatgcgta taacgagttc cgtgtgtggg ttgccggttc
     5221 gctggagggc cgcggtatgg atatcgcgtc cacggtgggt ccggtgattg tactgggtat
     5281 gctggtggcg ttctttgtgg ctcctgcgat taatgctttg agtatgggcg aggaggcggc
     5341 gaccagcctc ggcgtgagtg tgcgtacgac ccagaatttg acgttgctgg cggtgacggt
     5401 gcttgccggt gcggcgactg ctgcggtggg tccgattggt tttgtgggtt tggcggtgcc
     5461 gtttgtggtg cgtgccctac tcggtaatga tgtgcgctgg gtgaattatg gttcggcgct
     5521 gttgggtccg gtgtggctgc tgtgtgctga cgtgttggcg cgtgtgctgg tggctccgca
     5581 ggagactcag gtgggtattg tggcgactct tgccggtgcc ccggtgttct tgttcttgat
     5641 gactcgtcgt aaggtggagg ctctctaatg tcgaattctt ccgctgtttc gacggcgacc
     5701 gtcaccactg cagctaatcg ttctgcgcgt cgtagcggcc gcgatttggg cggtcgcccg
     5761 gtgttgactg tgcgcggtcc gctgagtgct caggtgccgt ggcgtgtgct gattttgaat
     5821 gtggcgttgg tggtgctgat tgcggcgctg gcgttttggg gcatgttgca gggtgattat
     5881 aagatcgccc cggagaagct gatcccggcg ctgctgggtg agggcaagca gattacggtg
     5941 actttcgctc agcagcgtgc ggcgcgtatt gtggcggcgc ttctggtggg tgcggcgctt
     6001 ggtctgtcgg gtgcgatttt ccaggtgatc tcgggtaatg ccctgggttc gccggatatt
     6061 atcggcttca cgaatggtgc cgcgaccggt gcgctgttgc agattattgt gttcaattcc
     6121 ggccccgttg aggttgctct gggcgctgtg gttggtggct tggcgacttc ggtgctggtg
     6181 tggttgttga cgcgccgtac gggtttgcat ggcttccgtc tggtgctggt cggtattggt
     6241 gtgggttcga ccctggcggc gttcaatgcg ctgctggtgg tgcgtgcttc gctgactcag
     6301 gcgcagaccg cggcgtcttg gcttgccggt tcgctcaatg acatcacgtg ggagcgcacc
     6361 tacgcgctgc tgggtctgct gctcgtggtg actccgctgc tgctgatgct ggtccgcccg
     6421 ctgggtgcga ttcgttttgg tgaccaggtg gcatccggtt tgggcgtgag cgtgaacgcg
     6481 taccgtgtgg cggctctgtt catcggtgtg cttctggttt cgctggcgac cgcgacgacc
     6541 ggcccgattg ccttcgtcgc tttggcggca ccgcacatcg cgaagactct gtctcgtagc
     6601 ggcggggtgg gcttcacctc cgcggcactt atgggtgcgc tcatggtgct cggctctgac
     6661 ctgattggcc gattcgctgt tcccggacgc atcattcagg tgggtgtggt gaccggcgcg
     6721 attggcggcc tgtacctgat ttacctgatt tacctcgaaa ggaagaagag ctagtgaacg
     6781 ctagtgtgac gacccgcctt gaaggcgaga acatggtggt tgcctacggt gagcatacgg
     6841 tgctcaacgg ggtagatttt caggtgccgg agggggagct gaccgttatc ctgggcccga
     6901 atgcctgcgg caagtcgacc actctgaagg ctcttgcccg cgtgaacccg ctcaaggacg
     6961 gcgaggttcg cctggacggc accccgctac cgcagatgaa gtcccgcgct atcgccaaga
     7021 tcctggcgat gctgccgcag accccggagg cgcctagcgg cgtgaccgtg gcggatgtgg
     7081 tggcgcgcgg ccgctacccg caccagtcgc tgctgcgttc ttggtccgat gaggacgagc
     7141 aagcctgcgt ggaggcgatg caggcggcga acgtgctgga gcttgctgag cgtcccattg
     7201 aggcgctctc gggcggtcag cgtcagcgcg tgtggattgc catgaccctg gcacagcaga
     7261 ccccgctgat tctgctcgat gagccgacca cctacctgga catcacgcac cagattgagg
     7321 tgctgaacct gacgaagaaa ttgcattccg aagggcgaac ggtagccgtg gtgttgcatg
     7381 acctgaacct cgctttcagg tatgctactc atgttgtgtt aatgaagcag ggccggatta
     7441 tcgctcaggg cgatccgcgt gcgataatta caccggaact tatccaggaa gtttttgacc
     7501 tgcaatcggt cattattcct gatccatgca ctggtacccc tttggttatt ccgaaggaga
     7561 accaaacaat tcatattgcc gctgacgcta tttcggcggc ccgcgaaagc gaatagtttt
     7621 cgcccctaag ccgcgtggga gttagcacca accgtctcag tacgggtgga aaagctcggc
     7681 attgcgccga gtagcgaacg ctaggatctg agggacccag gatcccctgc gcgtagggcg
     7741 cctacccggt gctcgcccgt ctttgacgca tgaacggatc cgagcactgg gtaggttcca
     7801 ttttgggaac ccgcagatga ggcaccgaga ctgccgcatg agaccttcac agtttgaagg
     7861 tttgatgcac ggtctcggtg cctcatctca tttaactgcc cggtttgtgg gggccactgt
     7921 ttgcgaccta cagttggggc ctgcatttga accccgcgct cgctgtcatg aatgtcatgt
     7981 tttggttctt tcgcttttcc ctttggctgg agtttgggta ggggatacca tagagtgagg
     8041 tagtagaggc taactaacga taatgcgcct cctcaccgat tctcaccgat tgagtgtttc
     8101 cacagaccaa ggaggaaccg ttgggcgagc acgaacccac cgcgaccgtt cccgcgcaga
     8161 gtatttctgc ccagaacact tctgcccaga acacttctga acaggctact tcggcgcagc
     8221 cgcgtaccgt tgcgccgacc gtgcgcccgg cccctcccaa gatcccgcgc cccgtaccgg
     8281 caccgcgcgt ggacagcccc cttatcagcg ccctcattgc tgaggcggtc agccccgaag
     8341 agctgaacgc ccgcatcctt gaggtcgtct ccgaaggcac ccccattatc gagctggtgc
     8401 accgcgaaga cggcagcatc agcgagaacg aacgcatcgt taccttcctg taccacaacg
     8461 agcaggcgga gcaggtgctc atgttcatca accgcctgac cgatgagaag aaccttgacc
     8521 gttccctcat ggcccgcatc gagggcactg gctggtggca gctgagcatg cagatggaaa
     8581 ccacctggcg tgcctcctac aacttcttgc cggcgctgcc cggcgagcgc cccgcttggc
     8641 tgggtgatga cgaccaggtg cgcttgcgcg ccgctctgga ttccggtgag ggtgacccgc
     8701 tgaaccccga gaccgcgtgc aaccgtatcg gtcgttgcat gggtgtggtg cagcttgagc
     8761 atgcgccggt gcaggagttc atcctgactc aggaagagat tgacgcgctg cccgcccccg
     8821 agtggatgca gacctctgac ggtcaccagt atgtgctcgg ccgcgtgggt gaccccgccc
     8881 cggatgcgcc gctgttcatc cagttcgacg gtgagatgtg gttcagtcag ggtatggagc
     8941 acaccctcaa ccgtgcccac gaggccggtc gtattccggc gatgcacgtg ttcttcctgc
     9001 actctggcgg tcgtgagaac cgctggaagg agctgaacgg cgacaacccg attgccgact
     9061 acctggtaga gatcgcgttc ccgcacctgg aggcagtgca cggcattaag accgcgccgc
     9121 agaacattgt gattaacggt cagtcgctgg gtgggctgtc ctccctgctg gcggtgctga
     9181 gccgcccgga ggcgtttggc ggcgcgatcg cgcagtcttc gtcgctgtgg caaccgcagg
     9241 tcatggaccg cctggacgag ctggaggcgg cgggcgagat tgatcgcctg cgccacctgt
     9301 accttgagat tgaggtgggg gagcaggagt gggttctggt accgcctcac cgcgagttga
     9361 aggagcgcct ggaaaagctg ggcctgaaga atgcgcgttg cacggccttc aacggcggtc
     9421 acgattatgc gtgctggcgc ggtgcgattg tgccggcgtt ggaacgtatt attgctgccc
     9481 gccgggaggc tgagcgcgct gagcggagct tagctgagga gtagcgagag atcgcctagg
     9541 gatcctgcac gggtagagca caccccgcat ggtgggcgtg cggggttccc gttagggtaa
     9601 acaccgccgc gcccgtatcc tagagaagta cagcctaaga gaagtgcaac actaccgcgc
     9661 cgcgaggggt gccgaagggt acccggcgca ggttgcgcac ccgccctcat tgacgagatg
     9721 gcatcacgct gcgaacgcac gcagcacgtg agcgctatag aaaccgcaaa cgacacagaa
     9781 atcgagagaa gatgaccgta gaacgtagcc ccctggcccc cacgccgctc atccccgagt
     9841 cttttgccgc gaagtaccgc gaagccggct actggattga ccagaccatc cccgagttcc
     9901 tgctagatgc atgccgcgcg aagccgcact tcccggcgct ggtggcgctc tcgcacgcgc
     9961 agctcgatga ggacggcaag cctcagcaga ttcgcctctc ctacggtgag ctggaggcgg
    10021 caggtcgtgc cgctgcggcg cgcctcgttc aggctggcgt gcagcccggt gaccgtgtgc
    10081 tgctgcagct gggtaacacc gccgagtacc tggtgtacct gctgggtatt ttctgggcgg
    10141 cggcgctgcc ggtgttctgc ctgccgcagc accgcaccac cgagctcgtg cactttgcga
    10201 cccgcaccga cgctgcggcg cacgtgttct cttcgctgac cccgggcgca gatttcgccg
    10261 ccctgcacga ggacgttgcc gccgagttgc gcaagaactc ccaggagccg ccggttgcta
    10321 tcgacgttgc ggagccgctg accccgctga ccgaggagga gctcgccgaa gagttcgtgc
    10381 ccggcgtcat ccagaacacc gagaacctgc gcgcgagcga gcaggtggcg ttcctgcagc
    10441 tctccggcgg tacgaccggc atttcgaagc tgattcctcg cacccacgcc gcctacctgt
    10501 actcggtgcg cggatcggtc gatatctgca agctgaacaa caacacgacc atgctcgtgg
    10561 tgctgcccgc cgcgcacaac ttcacgatga gctcgcccgg tattctgggc gtcatgtgcg
    10621 cctccggcaa gctggtgttt gcggcggatc cgtccccgca gactgcgttc cacctcattg
    10681 agatggaggg tgtgaccacc tccgcgctgg tgccgccgct ggctcaggcg tgggtcgcct
    10741 ccgcggagaa gcgcggcgtg tccctgccgt ctctgcagac cctgcaggtg ggcggttcga
    10801 agctggcccc ggcggttgcg ggcaagattg agtcggtgct cggctgcacc gttcagcagg
    10861 tgttcggcat ggctgagggt ctggtgaact acacccgctc gaccgacccg attgagatgc
    10921 gtctgaggac tcagggctac ccgatcagcc ccgacgatga aattctgatt gttgatgatc
    10981 aggaccagcc ggttaagcgc ggcgagagcg gccacctgct cacccgcggc ccgtacacga
    11041 ttcgcggcta ctacctggag gagaacgcga accgctacgg cttcaccgag gacggcttct
    11101 accgcaccgg cgacattgtg cgcctggtcg caggcaagta ccttgaggtg accggccgcg
    11161 cgaaggacca gattaaccgc aacggcgaga agattgccgt ggacgaaatc gaagagctgg
    11221 cgctgaccca ccccgacgtt tttgacgccg tggtcctggg catcccggat gagactgtgg
    11281 gcgagcgcgt gggcctggtc attgtgccgc aggaaggcgc cgacctgggc gaaaacccgc
    11341 gtcgcacgat gcacgagttc ttcacctcga agaagctcgc cgacttcaag attcccgagc
    11401 gcgtgcaggt tctgcaggag ctgcccacca cgaacgtggg taagatttct cgccgcgaac
    11461 tgcgcgccaa gcttgccgaa attttcggct aaaccctttg agctgatcat tttcagctaa
    11521 accgtacgcc cttattccta cccctattga ggagaaaaat gtccgcattt gagaccctgc
    11581 gccccatcat ggagaagtac atcgtcgagc ccgactccct gcagaccgct tttgacgagc
    11641 cgaccaccga cctgttctcc ctaggcatgg actctatggg cgcattcgcc ctgctcgacg
    11701 accttgccgc tgagggcgcc gtgattgagt ttaccgagct ggtggagaac ccgaccgtgg
    11761 agttcatcgc ctcccgcctg ggctaagcgt taccgcaccc cgagtgcccg cctgccgcga
    11821 atgcaggcgg gtacccgggg tgtttgctac tcgcttcgtt tttctgtgcg ccggttttac
    11881 gccgtattgt gtagctgcgt ttacccttgt cagtgcactt ctgtcagcgc acttctgtca
    11941 gcgcacttct gtcagcgtga agcggcgggg cagtagcctg cctttcacac ctacctttaa
    12001 cacaccgcat atcatcccta atccagaccc ctaatccaga cctttgagag gccaccatgg
    12061 gcgtagctga tactaccgca cccgctagct tcgggactgc ttccgacctt cgcaccgccg
    12121 cgaacccctc cgcacagcac agcgctgaca gcccctggct gccgctgacc actaacgcac
    12181 gcggcatcta ttttgccgcc gcgattgacc cgacgaaccc ctgctacaac accgcggagg
    12241 ttctgcaatg ccccgcagac accgacctcg ctcttctgcg tgaggctttt gaacagctct
    12301 accgcgagaa cgagggcttc cgcgtgcgca cccgcattgc cgacggtgct gcctcccagc
    12361 agattctgac cgaggaggcg ttcctcgcgg gcattgacct gctcgtggat gatggcgaac
    12421 tggacggggg cgaactggag gagggcgagc tgagcggcac cgctgaggcg ggggaggaga
    12481 acgcctctga cctgcccgaa tcagccctgc ctgactctga tttgcccgcg ccggtacgct
    12541 cctgggcaca gcgcctactc gcccagcccc tcgccaccga tgagggcgtg accgtacgca
    12601 gcgcagtggc gcgttatggc gggttcctct gggtgtacca ttccttctcc cacgtggttg
    12661 ccgacgggtt cgcggcgttc aacggcctct cccgcgtggc ggcgatatac cgcgctctgt
    12721 ccgccggtca gccggttccg gcaacccgcc gcatgagcct gcaacagcta ctcgatgccg
    12781 acgatgccgc ctccgacgcc cgcgacgaag acgtcgcctt ctgggaggcg agcggcgccc
    12841 tggagcagga agacacctcc ctggcgggtc gtaccgcatc cccgtcggcg cagtctgtgc
    12901 gcctggcgtt cagcattgac gtacccaccc agcaggccct gctggatgcg gcaaagcagc
    12961 acgctgtctc ctggccggtg ctggcgaccg cggccgtcgg ctcgtacctg gcgcgtgtgg
    13021 gtggctaccc gcaggcttcg ttcggtgtgc cgcagatgaa ccgcatgttc gcccgcaccc
    13081 tgccggaggc gacccgcgcc ctgggcacgg cgagcgcgca gaccggctgt accgcggtga
    13141 acgttctgcc ggtgcaggtt gcggcgactg gccccatcgc ggagtccctg cactcggtga
    13201 aggaacagta cgcccgcaat gcggagcatc cgctggctcg tcaggaagac ctcgagcgta
    13261 ctgcgcgtaa tgcccagtcc aggctgtttg gtgcgcagat taacatggtg ccctttgatg
    13321 cggtgctgcc gctggcggcg ccctcgaagg acgagtccgg agccgcggta ccgaccgcgc
    13381 gcattcacaa tatctctgcc ggtcccgttg ctgacgcgac cttcaccctg cgcggcatgc
    13441 ccggccgcgg caacagcatc tcctgcgaga ttgacatgaa cccggcgctc tacaccgctg
    13501 aggagctgga acgtcacgcc gcccgcctgc gcgagtggtt gcccgcctac gcggcggagg
    13561 cgcagcgcga gggtgcctcc ctgaacaacc tgggtttggc gaccgaggcg gagcttgcga
    13621 ccctgcgcga gctgaccgcc ccggcgctta ccgagcaccc gatggagtac aagaccctgc
    13681 tgggccgctt ccgtgacgcg gtggcggcgc atccgcaggc gctcgcggtg ctggattctg
    13741 cccccgcgcc cggtgaggtg ctcacccccg agtcggatcg cgcctacgct tttgaccgcg
    13801 ccctcaccta tgccgaactg gacgagcgcg cccgtgcgct tgccgtgcag ctgctggact
    13861 ggggcgtttg cccttccgac gcggtgggtc tgcgtgtgca ccgcggcgcc gagcagtacg
    13921 tggcgctgta cgccctgctg tacgctggcg ccacctacgt gccggtgctt cctgatctgc
    13981 ccgccgagcg cgtgggcgtg atgatggagg acgccgaatg ttccctgctg ctgcacggcc
    14041 ccggtctgca gccgctgagc gcggaagagc tgaacccgca ggaaccgcag cgtcacgcga
    14101 acctgcccca gcacacccta ccgcagctga gcatcgagga acctgtacag gcacccgccg
    14161 ctgaggagct tccgggcacg aaaaccggcc tggacgagga cgcttacgtg ctcttcacct
    14221 ccggttctac gggcaggcct aagggcgttg ccatcagcca ccgcgcgatt gataaccgcc
    14281 tgcgctggca gcagcaccag attccggtgg gggagggcgc ccgcgttctg cacaagactc
    14341 ccatctcctt tgacgtgcac gtgtgggagc tgtactggcc tctcgccgag ggtgccgccg
    14401 tggtcattgc cgccccggag ggtcaccgcg accccgcata cctggcgcgc gtgattgccg
    14461 agcagtccgt cacggcggtg cactttgtgc cgaccatgct gtcggcgctg acctcttcgc
    14521 cggcggcgcg ccgcatcctg gctgatgccg gcttcggtca ggaccgggag cagcccctgc
    14581 gctacgtggt ctgctcgggt gaggcgctgc agaaggacca ggtgcaggct gcgggcgagg
    14641 ttctgggcgt gtacccgctg aacctctacg gcccgaccga ggcggcggtg gacgtgacct
    14701 tctgggagac gtccaacgac ccgcagcgcg agagcgtgcc cattggcgag ccggtctgga
    14761 acaccggcac cctgattctt gacccgaccg gccaccccgt gccggtgggt gtgacgggtg
    14821 aactgcacct gtcgggtgtg cagctggcgc gcggctacaa gaacaacccg caggcgaccg
    14881 cggcggcttt cgtggagcag gctcctgccg gtgcgctcgc gctgctgaac ggtgagagtc
    14941 agcgcctgta ccgtacgggc gatttggcgt gctgggagat tcttcccgat ggtcgcgccg
    15001 tcattggcta ccgcggccgc acggactatc agatcaaggt gcgcggtcag cgcctggagc
    15061 tgggcgatat tgagatggct cttgccgcgg ttgagggtgt gagcgcttcg gtggctctgc
    15121 tgtaccgcgg cctgcgtgag cctgccctgg cggcggtgct ggaggtcggc gacgtgcccg
    15181 ccgagcgtgc cgagcagctg gtggagacgg cgcgcgagca ttgtgcgcag gttctgccgg
    15241 actacatggt gccgaccctg tggcataccc tgcctgctct gccggtgagc ccctccggta
    15301 aggcggatcg caagctgttg gcgtccctgg acctgacccc gcagacttct gatgctgagg
    15361 gcccgcacgg tctgctggag cagcagctgt gctcgattat tgccggtgtg ctgggtcgtg
    15421 agcgtttcgg cgtggatgag gacttcttcg cctcgggcgg tcattcgctg gcggctcttg
    15481 aggtgattgc cgcggttgag gaacagctgg gtctgagcgt gagcatcggt gcgctttttg
    15541 cacatccgac cgtgcaggct ttggcggcgt ccattgcggg cgagcgcggc gagggtgcgg
    15601 agttcgcgcc ggttctgccg ctgcgagaac aacctaccgc gcatgacgct accgatgccc
    15661 ccgcgccgct gtttatcctg ccgcctgcgg gtggtttggg ctggtgctat gcggggtacc
    15721 tttcgcatct tccggctcag cagggtgtgt atgctgtgca ggctgaggcg ttctctgatc
    15781 cgcaggctgg gtttgcgtcg agtctgcagg agttggctga gggctacctg gcacagattg
    15841 agaagaccct ggcggagcgt tcgttgccgc gtcgttttgc gttgatgggc tggtctgttg
    15901 gcggtactgc cgcggtgcag gttgcggctc tggcgcaggc tgcgggtgcg caggttgagc
    15961 gcgtcgtcct gttggatgcg tatccttcgg agcagtggca gggtgtgcct gcgccggatg
    16021 agcaggagag cttccgtgcg ctgctgcgta tgggtggttt gccggagcct gccgccgatg
    16081 agcagcttga cctgccgagt accctggaac gcctgcagaa ggcggggtcg gcgatgggtt
    16141 acctaccgga ggagaagctg ggcgtgtgcc tgggtagtat gcgcgcttcg gcggcgttga
    16201 tgcgtggtgc tgagcaggcg ttctttgaag gggacgtgtt gctggtgggt gtgccgcatg
    16261 aggatcagcc gtacctggat gcggcgggtt ggtcggcgca tgcctcgtcg ttccgtgcgg
    16321 tgctgctgga gggtacgcac cctgatctgg tgaatccggc gcgtctggcg gaggtgaccg
    16381 gccacttcgc cggctag
//
