LOCUS       BGC0002690             11809 bp    DNA     linear   BCT 28-DEC-2018
DEFINITION  Verrucosispora sp. FIM060022 scaffold11, whole genome shotgun
            sequence.
ACCESSION   BGC0002690
VERSION     BGC0002690
KEYWORDS    .
SOURCE      Verrucosispora sp. FIM060022
  ORGANISM  Verrucosispora sp. FIM060022
            Bacteria; Actinobacteria; Micromonosporales; Micromonosporaceae;
            Verrucosispora; unclassified Verrucosispora.
COMMENT     Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-08 11:25:37
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11809
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11809
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[5000:6809]"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="5000"
                     /product="siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..6809
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="5000"
                     /product="siderophore"
                     /protocluster_number="1"
     cand_cluster    1..11809
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..11809
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002690"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..11809
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="siderophore"
                     /region_number="1"
                     /rules="IucA_IucC"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            184..1200
                     /locus_tag="EG812_24945"
     CDS             184..1200
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078:LacI family
                     transcription regulator (Score: 315.1; E-value: 9.2e-96)"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007461014.1"
                     /locus_tag="EG812_24945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LacI family transcriptional regulator"
                     /protein_id="RUL90625.1"
                     /transl_table=11
                     /translation="MATLSDVARRAGVSPATASRVINGSSKPVTDELRERVLQAVAELQ
                     YVPNAHAQLLARSHRGAVGVIVHDVSDPYFSEITRGLQRVATDQGRLLMICNSYRDPDR
                     ELEYVELLRGQQVAAIILAGSGYHDPDFTTLLNGKLAAYEATGGRVAVIGRHEHSGDAV
                     MPDNRDGARLLGQEICRLGHQRIGVVAGPRVLTTTTDRLTGLREALAEHGRQLPEQLVR
                     YADFDRDSGAEATAALLDAEPALTAIAALNDSMAIGALSLLRSRAVAVPDRVSVFGFDD
                     MPMARDVTPALTTIRLPLVEMGARAMALALDGGSAGPRVESLAAELVRRDSSGPPPH"
     gene            1245..3947
                     /locus_tag="EG812_24950"
     CDS             1245..3947
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013733812.1"
                     /locus_tag="EG812_24950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="RUL90626.1"
                     /transl_table=11
                     /translation="MRRLLISAALVVALVTGATGPAAAEPPEDPTPRSAVEGWSVADGE
                     LTWRSDTPVPMGDAAVEFWSGQRRLGAARPHPDGRTFSLPLTAPVEPDELAVRVGGRRI
                     DADAPRERARRSGPVAAMAAPQPAGPVDPGRPGPYRQITGEYDLPGVTLPQFPEKVEMR
                     AVVVAPQGTTGARPLALFLHGRHAVCYRGDEQVPQQWPCPADTEPIPSHRGYLQAQRLL
                     ASQGYVTVSISANGINGQDWAAADGGAQARSSLVRLHLAKWADWAGTGRAGAPAIVRAA
                     PRADLSQVFLMGHSRGGEGVSRAAMDSLTPPPRAQDGYPGTVRWTVRGMLLIGPTLFGH
                     NPVPDVPSVTILPGCDGDVFDLQGQMFVDATRGLSPSRALRSALYVIGANHNYFNTEWT
                     PGQSVAPSQDDFYTSDDEPDPVCSPGMPSRLTATQQQTVGATYIAAAARLFVGGDDRVR
                     PLLDGTGRRAPSADPARVLAHALGGNRTPVLTPDASTQLSGGARICDQVTDDADRSCLG
                     LNDRNALLAHFTPFLWTIPEPDRYAAELAWSRAGTPILLAPARPVSVAGARDLAMRIII
                     PPNTTGTRLDVTVVGTDGRRSRLGEVRVDGLPGTGNTTSYWAQEVRVPLQGAPARLAAI
                     EITPRTAFGQAWLLDAWGWKPGTPDPRAPRLPRLDIGTLEVAEGDSGTKTYEIPVTITG
                     RGSATVQLNLTDDTFVSRSWLATVRPGQRSIRVPAEVVGDTLWNYTERHLLTAKAQHGM
                     VVGSYLGGLDVLNDDPAPTITVEAAQRVTEGETLTWRFTASAPTEQGIFAIAWPQPPTA
                     GPELSTMDVDPDWFTEHAYSPVEPERPLSQTWLVPYLELAPDAVVAEITVPTITDSVVE
                     PDEWIELRFDQEPDGPQLPPVLTGVVTDG"
     gene            3984..4994
                     /locus_tag="EG812_24955"
     CDS             3984..4994
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013733811.1"
                     /locus_tag="EG812_24955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="RUL90627.1"
                     /sec_met_domain="APH (E-value: 7.9e-19, bitscore: 57.5,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVPPLSPTQQVLSPDDVADYIAASFGADRQVADCGPLTGGGFAT
                     VWWVRLDDGADVVLKVGPPSHVPLLRYETGMLAAEARYFRLVAARAPQVPVPPVLHHGR
                     DTRLGEWLVTGRLPGRALPDLDGAGEGARYDFGATMATLHRITGDRFGYDAGRTGGTTW
                     SAAFAAIIDDLLADAADWNVTLPAPPQRFRELVARHTDLLDQVRRPALLHFDGWDGNVL
                     AAPDAHGAYRMCGLVDGERFLYGDPMLDLVSPLLFRRAEDEPEHPFLHGYADAVGTPLV
                     FDDRVRRRLALYRMHLHLLMTVEMPSRGITVDNDPGRHTLLAELLDRDLADLSRG"
     gene            complement(5001..6809)
                     /locus_tag="EG812_24960"
     CDS             complement(5001..6809)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018720107.1"
                     /locus_tag="EG812_24960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="IucA/IucC family siderophore biosynthesis
                     protein"
                     /protein_id="RUL90628.1"
                     /sec_met_domain="IucA_IucC (E-value: 3.1e-84, bitscore:
                     271.4, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTIDPVAHLRPQTWERANRLLVRKALAEFAHERLITPEPDGPAT
                     DPTGARWYAVTSDCGTVRYRFTARLRILEHWDIDPDSITRHHDGRPQPLDAVDLCLDLR
                     TSLGLSDRILPVYLEEISSTLAGSAYKLDRALPAAAKLIEADFQTIETSMTEGHPCFVA
                     NNGRLGFGVDEYHRYAPEAARPVRLIWLAAHRDHATFTSAADLDYATLLRTELDEATLA
                     RFAQTMAALDLDLADYLLIPVHPWQWWNKLSVTFAGEVARRRLVHLGESDDDYLAQQSI
                     RTLFNVSAPHRHYVKTSLSVLNMGFMRGLSAAYMEATPAINDWLADLIAADEVFRATGL
                     TIIRERAAVGYRNRQYEAATDRYSPYRKMLAALWRESPVPTLAPGERLATMASLLHVDA
                     DGRSFAAELITASGLAPAQWLRRYLHAYLTPLLHAFYAYDLAFMPHGENVILVLRDHAV
                     QRVIFKDIAEEIVVMSTEATLPPAVERIRAEVPEDMKLLSIFTDVFDCFFRFLGATLAD
                     QGIADEEIFWRTVADCATDYAARVPHLADRLARYDLFAPEFALSCLNRLQLRDNQQMVD
                     LADPSAALQLVGALTNPLARFTPTAG"
     misc_feature    complement(5958..5960)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(6806..7384)
                     /locus_tag="EG812_24965"
     CDS             complement(6806..7384)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1203:putative siderophore biosynthesis protein (Score:
                     150.9; E-value: 1.1e-45)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013733807.1"
                     /locus_tag="EG812_24965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="N-acetyltransferase"
                     /protein_id="RUL90629.1"
                     /transl_table=11
                     /translation="MSATVHTRTDPVLGEFALRTLDVATDAALLHRWVTHPKAAFWLMQ
                     DADLAAVVEEYERIAVHPHHDAFLGLWRGEPAFLAERYDPAQVELVGLYDAQPGDVGMH
                     FLCAPTETPVHGFTHAVLTTVMSWLFADPDTARVVVEPDVRNTAVHALNAAVGFDVIGP
                     IAKPEKQALLSICTRERFLAATRSQGATL"
     gene            complement(7381..8661)
                     /locus_tag="EG812_24970"
     CDS             complement(7381..8661)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1080:lysine/ornithine N-monooxygenase (Score: 407.2;
                     E-value: 1.2e-123)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018813388.1"
                     /locus_tag="EG812_24970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alcaligin biosynthesis protein"
                     /protein_id="RUL90691.1"
                     /transl_table=11
                     /translation="MDSYDVIGIGLGPYNLGLACLTAPIAEIDALFLEARDDVSWHPGM
                     LLESSRLQTPFLADLVTLADPTSPFSFLAYLKEIGRLYPFYIRESFFPLRAEYDAYCRW
                     AAAKLPNLRFGHQVSAVEYDPTSEQYVVTATVGGDTVTHRARHLVLGTGTPPHLPQACA
                     GLDSDAVHNSRYLEHRDALRAKRSITIVGSGQSAAEIYHDLLSDIGTYGYQLNWVTRSP
                     RFFPLEYTKLTLEMTSPDYVDYFHALPEQTRYDLEAEQKGLFKGISADLVNDIFDLLYA
                     TSVPGPVNTRLLTNTELTGVTYDRSTGRHTLRLRHVEQGRDHTLDTEGLVLATGYRYQV
                     PAFCDPIRDRLRFDGHGRLDVARNYSVDHTGRGIFLQNGGTHTHSITSPDLGMGPYRNS
                     WIIRELVGREVYPIEKSITFQEFGVPA"
     gene            complement(8697..10220)
                     /locus_tag="EG812_24975"
     CDS             complement(8697..10220)
                     /NRPS_PKS="Domain: Aminotran_5 (145-286). E-value: 3.3e-08.
                     Score: 24.6. Matches aSDomain:
                     nrpspksdomains_EG812_24975_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1180:Decarboxylase, pyridoxal-dependent (Score: 369;
                     E-value: 5.2e-112)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013733805.1"
                     /locus_tag="EG812_24975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="RUL90630.1"
                     /transl_table=11
                     /translation="MTLPVHTAPPPSAARAHLFHDGTVDDYRAAVTAGADRVARRVAEA
                     TGPFTGVRPEQLAPLVDAIDLDRPLHDTTAALDELDEVYLRDAVWFHHPRYLAHLNCPV
                     VIPALLGEAVLSAVNSSMDTWDQSAGATLIERRLIDWTAARIGLGPAADGVFTSGGTQS
                     NLHALLLAREEALAGASPTDRRILLPHLRIITSAAGHFSVQKAAKLLGLAPDAVVVVQT
                     GPDRRMRAGAVRHEISRCRRAGLTVLAVVATAGTTDFGTIDPLDEIAEVCGTSGVWLHV
                     DAAYGCGLLVSPTRRHLLDGIERADSVTVDYHKSFFQPVSSSAVLVRDRHTLRHATWHA
                     DYLNPARMVAERIPNQVDKSLQTTRRFDALKLWLTLRVMGPDAIGELFDEVCDRAAQAW
                     QLAAADPRFEVLTASALSTVVFRWRPAGTPAELADAANLHARSALAASGLAVVAGTRVD
                     GRQYLKFTVLNPATSTDDVAYVLDLIAEHAGRYAHTHAVSTPAVPCRVG"
     aSDomain        complement(9363..9785)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EG812_24975_Aminotran_5.1"
                     /evalue="3.30E-08"
                     /label="EG812_24975_Aminotran_5.1"
                     /locus_tag="EG812_24975"
                     /protein_end="286"
                     /protein_start="145"
                     /score="24.6"
                     /tool="antismash"
                     /translation="IGLGPAADGVFTSGGTQSNLHALLLAREEALAGASPTDRRILLPH
                     LRIITSAAGHFSVQKAAKLLGLAPDAVVVVQTGPDRRMRAGAVRHEISRCRRAGLTVLA
                     VVATAGTTDFGTIDPLDEIAEVCGTSGVWLHVDAAYG"
     gene            complement(10361..11392)
                     /locus_tag="EG812_24980"
     CDS             complement(10361..11392)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1033:iron compound
                     ABC transporter, periplasmic (Score: 92.5; E-value:
                     3.6e-28)"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018215730.1"
                     /locus_tag="EG812_24980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="RUL90631.1"
                     /transl_table=11
                     /translation="MPDPVSARRLSRRGLLAAGGAAALTAVLVGCGRDEAEKSSTSNGS
                     GPWSFTDDRPEAVTAPARPARVVAFTGSAAALVDFGLGREVVGVFGETKKADGSKEAQA
                     GDLDVESVEILGNVWGEFSVEKYAALRPELLVTHMYDPGAYWYVPDESKDKILPLAPVV
                     TITTARVPMTKPIARYAALAESLGADLSAPKVTDAKARFEAAAEAVRQAVKANPGIKVL
                     AASGSPDLFYVSNPKVSTDLMYFAELGVDIVVPTKLESGDYFEALSWENAGKFPADLIL
                     LDNRSTALQPADLAAKPTWKQLPAVQAGQVTGWDAVPRFSYAGAAPLLEDLAKAIQGAK
                     KLT"
ORIGIN
        1 aagggctttc ctggcggcga cgccgccgaa cttccgacgg cagcacctcg gcacgaaccg
       61 gccgaaccgg gcctatctcc cggtgtgacc tgcgcgaacc acgcgacggt aaaacacccg
      121 cactgcggta cggtgacgct ggccgtcaca ggcgcggccg acgcgacacg ggaggggacg
      181 cgggtggcga cgctgtccga tgtggcgcgg cgggcgggag tctcccccgc cacggcttct
      241 cgagtgatca atggcagcag caagccggtc accgacgagt tgcgcgaacg ggtcctgcag
      301 gccgtcgccg agttgcagta cgtgcccaac gcccacgccc aactgctggc ccgctcccat
      361 cgcggcgccg tcggtgtcat cgtgcacgac gtctccgacc cgtacttctc cgagatcacc
      421 cgagggctgc aacgggtcgc caccgaccag ggtcggctgc tgatgatctg caacagctac
      481 cgggacccgg accgggagtt ggagtacgtc gaactgctgc gcgggcagca ggtggccgcc
      541 atcatcctgg ccggctccgg ctaccacgat cccgacttca ccaccctgct caacggcaag
      601 ctggccgcgt acgaggccac cggcgggcgg gtcgcggtga tcggccgcca cgagcactcc
      661 ggtgacgcgg tgatgccgga caaccgcgac ggcgcccggc tgctcgggca ggagatctgc
      721 cggctcggcc atcagcgcat cggggtggtg gccgggcccc gggtgctgac caccaccacc
      781 gaccggctga ccgggctgcg cgaggcgctc gccgaacacg gtcggcagct accggaacag
      841 ctcgtccggt acgccgattt cgaccgggac agcggcgccg aggcgaccgc cgccctgctg
      901 gacgccgaac ccgcactgac cgcgatcgca gcgctcaacg actcgatggc catcggcgcg
      961 ttgtcgctgc tgcgctcccg ggcggtggcg gtgcccgatc gggtcagcgt cttcggtttc
     1021 gacgacatgc cgatggcccg cgacgtcacc ccggcgctga ccacgatccg gttgccgctt
     1081 gtcgagatgg gtgcccgggc gatggcgctg gccctcgacg gtggttccgc cgggccccgg
     1141 gtcgagtcgc tcgccgccga actggtccgc cgcgacagtt ccggaccgcc gccgcactga
     1201 ggtgcatcac gggagatttg cgcgaatggg atagatatag tcacatgcgt agactcctga
     1261 tctcagccgc gctcgtggtg gcgctggtga ccggggccac cgggccggcg gccgccgagc
     1321 cacccgagga ccccactccc cgatccgccg tcgaaggctg gtcggtggcc gacggcgagc
     1381 tgacctggcg ctccgacaca ccggtgccga tgggcgacgc cgccgtcgaa ttctggtcgg
     1441 gccagcggcg gctcggcgcg gctcgtccgc acccggacgg tcgaaccttc agccttccgc
     1501 tgaccgcgcc ggtcgaaccc gacgaactcg cggtgcgggt cggcggcaga cgaatcgacg
     1561 cggacgcccc acgcgaacgc gcccgccggt cgggaccggt cgccgccatg gcggccccgc
     1621 agcccgccgg ccccgtcgac cccggcaggc ccggaccgta ccgacagatc accggcgagt
     1681 acgacctgcc cggggtcacc ctgccgcagt tcccggaaaa ggtggagatg cgggcggtgg
     1741 tggtcgcgcc gcagggcacc accggcgccc ggccactggc gctgttcctg cacggccgcc
     1801 acgccgtctg ctaccggggc gacgagcagg tgccccagca gtggccgtgc ccggccgaca
     1861 ccgagccgat cccgagccac cgtggctacc tgcaggcgca gcggctgctc gcctcacagg
     1921 gatacgtgac cgtgtccatc tcggccaacg ggatcaacgg tcaggactgg gccgccgccg
     1981 acggcggtgc ccaggcccgc tcctcgctcg tgcggctgca cctggcgaag tgggccgact
     2041 gggccggcac cggccgtgcc ggcgcaccgg ccatcgtgcg ggccgcgccc cgggccgacc
     2101 tgtcccaggt gttcctgatg ggtcactccc gtggtggcga gggggtcagc cgggcggcga
     2161 tggactcgct caccccaccg ccgagggcac aggacggcta ccccggcaca gttcgctgga
     2221 ccgtacgcgg catgctgctg atcggtccca cgctcttcgg gcacaacccg gtgccggacg
     2281 ttccgtcggt gaccatcctg cccggctgcg acggtgacgt cttcgatctg cagggccaga
     2341 tgttcgtcga cgccacgcgg gggctcagcc cgagtcgcgc actgcgcagc gcgctgtacg
     2401 tgatcggggc caaccacaac tacttcaaca ccgaatggac gcccggacag tcggtggcac
     2461 cgtcccagga cgacttctac accagcgacg acgagccgga cccggtctgt tcaccgggca
     2521 tgccgagccg gctcaccgcc acccagcagc agaccgtcgg cgccacctac atcgctgccg
     2581 ccgcgcggct cttcgtcggt ggtgacgacc gggtccggcc gctgctcgac ggcaccggcc
     2641 gacgggcgcc ctcggccgac ccggcgcggg tgctcgccca cgccctcggc ggcaaccgca
     2701 cgccggtgct caccccggac gcgtcgacac agctgtcggg tggggcccgg atctgcgacc
     2761 aggtcaccga cgacgcggat cggtcctgcc tcggcctgaa cgaccgcaac gccctcctgg
     2821 cgcacttcac gccgttcctc tggaccattc ccgagcctga ccggtacgca gccgagctgg
     2881 cctggtcccg tgccggcaca ccgatcctgc tggctccggc ccggccggtt tccgtcgccg
     2941 gtgcccgtga cctggcgatg cggatcatca tcccaccgaa cacgaccggc acccggctgg
     3001 acgtgaccgt cgtcgggacc gacggccgac gcagccggct gggcgaggta cgggtcgacg
     3061 gcctgcccgg caccggcaac acgacctcct actgggcgca ggaggtacgg gtgccactgc
     3121 agggggcacc ggcacggctg gccgccatcg agatcactcc acgtaccgcg ttcgggcagg
     3181 catggctgct cgacgcgtgg ggctggaagc cgggcacccc cgacccgcgt gccccccgcc
     3241 tgccgcggct cgacatcggc accctggagg tggccgaggg tgactccggc acgaagacgt
     3301 acgagatccc ggtgaccatc acgggacgcg gcagcgcgac ggtacagctg aacctgaccg
     3361 atgacacgtt cgtcagccgc tcctggctgg ccaccgtccg gcccggtcag cgcagcatcc
     3421 gggtgccggc cgaggtggtc ggtgacacgc tgtggaacta caccgagcgg cacctgctga
     3481 ccgccaaggc gcagcacggc atggtggtcg gcagctacct cggcggcctc gacgtgctca
     3541 acgacgatcc ggcgccgacc atcactgtcg aggccgccca gcgcgtcacc gaaggcgaga
     3601 cgttgacctg gcgtttcacc gcgtccgcgc cgacggaaca gggcatcttc gcgatcgcct
     3661 ggccgcagcc gcccaccgcc ggccccgagc tgtccaccat ggacgtcgat ccggactggt
     3721 tcaccgaaca cgcgtactcc ccggtggagc ccgaacggcc gctgtcgcag acctggctgg
     3781 tgccgtacct ggaactggcc ccggacgcgg tcgtcgctga gatcaccgtc ccgacgatca
     3841 ccgactcggt ggtcgaaccg gacgagtgga tcgagctgcg cttcgaccag gaaccggacg
     3901 ggccgcagct gccaccggtg ctgaccggtg tggtgaccga cggctgagcg gggacgccgc
     3961 ggtggcaccg gtacggatac cctgtgccgg tgccaccgct gagccccacc cagcaggtcc
     4021 tctcccccga cgacgtggcc gactacatcg ccgcctcgtt cggcgcagac cggcaggtcg
     4081 ccgactgcgg gccgctgacc ggcggcgggt tcgccaccgt ctggtgggta cgcctcgacg
     4141 acggcgcaga cgtcgtcctc aaggtcgggc caccgtcgca cgtgccgctg ctgcgctacg
     4201 agaccgggat gctcgccgcc gaggcccgct acttccggct ggtcgccgcc cgggccccgc
     4261 aggtgccggt gccgccggtg ctgcaccacg gtcgcgacac ccgcctcggc gagtggctgg
     4321 tcaccggccg gctgcccggc cgggcgctgc ccgacctgga cggcgccggc gagggcgcac
     4381 gctacgactt cggggcgacg atggccaccc tgcaccggat caccggtgac cggttcggct
     4441 acgacgccgg ccgtaccggc ggcaccacct ggtcggcggc gttcgcggcg atcatcgacg
     4501 atctgctcgc cgacgccgcc gactggaacg tcacccttcc cgcgccgccg cagcggttcc
     4561 gcgagctggt ggcccggcac accgacctgc tcgaccaggt acgccgaccc gccctgctgc
     4621 acttcgacgg ctgggacggc aacgtgctgg ccgcgcccga cgcgcacggg gcgtaccgga
     4681 tgtgcgggct tgtcgacggc gaacggttcc tctacggcga cccgatgctg gacctggtct
     4741 cccccctgct gttccggcgc gccgaggacg agccggaaca tccgttcctg cacggctacg
     4801 ccgatgccgt cggcacgccg ctggtcttcg acgaccgggt acgtcgccgg ttggcgttgt
     4861 accggatgca cctgcacctg ctgatgaccg tggagatgcc cagccggggc atcaccgtcg
     4921 acaacgaccc cggccgacac accctgctcg ccgagctgct cgaccgcgac ctggcggacc
     4981 tgagccgcgg ctgatgccgg tcacccggcc gttggtgtga agcgggccag ggggttggtg
     5041 agggcgccga cgagttgcag ggcggccgac gggtcggcca ggtcgaccat ctgctggttg
     5101 tcgcgcagtt gcagccggtt gaggcaggac agggcgaact cgggggcgaa caggtcgtag
     5161 cgggccaggc ggtcggccag gtggggtacc cgggcggcat agtcggtggc gcagtcggcg
     5221 accgtacgcc agaaaatctc ctcgtcggcg atgccctggt cggcgagagt ggcgccgagg
     5281 aagcggaaga agcagtcgaa gacgtcggtg aagatggaca gcagcttcat gtcctccggc
     5341 acctcggcgc ggatccgttc caccgccggt ggcagggtgg cctcggtgct catcaccacg
     5401 atctcctcgg cgatgtcctt gaagatcacc cgttgtacgg cgtggtcgcg cagcaccagg
     5461 atgacgttct cgccgtgcgg catgaacgcc aggtcgtagg cgtagaaggc gtgcagcagc
     5521 ggggtgaggt aggcgtgcag gtagcggcgt agccattgcg ccggtgccag cccggaggcg
     5581 gtgatcagtt cggcggcgaa ggaccggccg tcggcgtcga cgtgcagcag cgaggccatg
     5641 gtggccagcc gttcgccggg ggccagggtg ggcaccgggc tctcccgcca cagcgcggca
     5701 agcatcttgc ggtacggcga gtagcggtcg gtggcggcct cgtactgccg gttgcggtag
     5761 ccgacggcgg cccgttcccg gatgatcgtc aggccggtgg cccggaacac ctcgtcggcg
     5821 gcgatcaggt cggccagcca gtcgttgatg gccggggtgg cttccatgta cgccgccgac
     5881 agtcctcgca tgaagcccat gttcagcacc gacagcgacg tcttgacgta gtgccggtgc
     5941 ggcgcgctga cgttgaataa ggtgcggatc gactgctggg cgaggtagtc gtcgtcgctc
     6001 tcaccgaggt gcaccaggcg gcggcgggcc acctcaccgg cgaaggtgac cgacagcttg
     6061 ttccaccact gccaggggtg caccgggatg agcaggtagt cggccaggtc caggtcgagg
     6121 gcggccatgg tctgggcgaa ccgggccagg gtcgcctcgt ccagttcggt gcggagcagg
     6181 gtggcgtagt cgaggtcggc ggcgctggtg aaggtggcgt ggtcgcggtg ggcggccagc
     6241 cagatcaggc gtacgggtcg ggcggcctcg ggggcgtagc ggtggtattc gtcgacgccg
     6301 aagccgaggc ggccgttgtt ggccacgaag cagggatgcc cttcggtcat cgacgtctcg
     6361 atggtctgga agtcggcctc gatcagcttc gccgccgcgg gcagggcccg gtccagtttg
     6421 taggcgctgc cggccagggt ggagctgatc tcctccaggt agaccggcag gatccggtcg
     6481 ctgaggccga gcgaggtgcg caggtccagg cagaggtcga cggcgtcgag gggttgcggt
     6541 cggccgtcgt ggtgtcgggt gatgctgtcc gggtcgatgt cccagtgctc caggatgcgc
     6601 agccgggcgg tgaaccggta gcggacggtg ccgcagtcgc tggtcaccgc gtaccagcgt
     6661 gctccggtgg ggtcggtggc ggggccgtcc ggctcggggg tgatcagccg ctcgtgggcg
     6721 aactcggcca gcgccttgcg taccagcagc cggttggccc gctcccaggt ctgcgggcgc
     6781 aggtgggcga ccgggtcgat ggtggtcaca gggttgctcc ttggctacgg gtggcggcga
     6841 ggaaccgctc gcgggtgcag atgctgagca gggcctgctt ctccggtttg gcgatcgggc
     6901 cgatcacgtc gaagccgacg gccgcgttga gggcgtgcac ggcggtgtta cggacgtccg
     6961 gctcgaccac cacccgggcg gtgtcggggt cggcgaacag ccaggacatc acggtggtga
     7021 gcacggcgtg ggtgaagccg tgcaccgggg tctcggtcgg cgcgcagagg aagtgcatgc
     7081 ccacgtcacc gggctgggcg tcgtagagcc cgaccagctc gacctgggcc gggtcgtacc
     7141 gttcggcgag gaaggcgggc tcgccgcgcc acagtccgag gaaggcgtcg tggtgcggat
     7201 gcacggcgat ccgctcgtac tcctcgacga ctgcggccag gtcggcgtcc tgcatcagcc
     7261 agaacgccgc cttggggtgg gtcacccagc ggtgcagcag cgcagcgtcg gtggccacgt
     7321 cgagcgtacg cagggcgaac tcgccgagca ccggatcggt ccgggtgtgc acggtggcgc
     7381 tcatgcgggc accccgaact cctggaaggt gatcgacttc tcgatcgggt acacctcccg
     7441 gccgaccagc tcgcggatga tccacgagtt gcggtacggg cccatgccga gatccggtga
     7501 ggtgatgctg tgcgtgtggg tgccgccgtt ctgcaggaag atcccccgcc cggtgtggtc
     7561 gacgctgtag ttgcgggcca cgtcgaggcg accgtggccg tcgaagcgca gccggtcgcg
     7621 gatcgggtcg cagaaggcgg gcacctggta gcggtagccg gtggccagca ccagtccctc
     7681 ggtgtccagg gtgtggtcgc gtccctgctc gacgtggcgc agccgcaggg tgtgccggcc
     7741 ggtggaccgg tcgtaggtga ccccggtcaa ctcggtgttg gtcagcagtc gggtgttcac
     7801 cgggccgggc acgcttgtgg cgtagagcag gtcgaagatg tcgttgacca ggtcggcgga
     7861 gatgcccttg aacagcccct tctgctcggc ctccaggtcg tagcgggtct gctcgggcag
     7921 ggcgtggaag tagtccacgt agtccggtga ggtcatctcc agggtcagct tggtgtactc
     7981 cagcgggaag aaccggggtg aacgggtcac ccagttcagc tggtagccgt acgtgccgat
     8041 gtcggagagc aggtcgtggt agatctcggc ggcgctctgc ccgctgccga cgatggtgat
     8101 gctgcgtttg gcgcgcagcg cgtcacggtg ttcgaggtag cgggagttgt gcaccgcgtc
     8161 ggagtccagt ccggcgcagg cttgcggcag gtgcggcggg gtgccggtgc cgagcaccag
     8221 gtgccgggcc cggtgggtga cggtgtcgcc gccgaccgtg gcggtgacca cgtactgctc
     8281 gctcgtcggg tcgtactcga cggcgctgac ctggtggccg aagcgcaggt tgggcagctt
     8341 cgcggcggcc caccggcagt acgcgtcgta ctcggcgcgc agcgggaaga agctctcccg
     8401 gatgtagaag gggtagagcc ggccgatctc cttgaggtag gcgaggaagg agaacggtga
     8461 ggtggggtcg gccagggtga ccaggtcggc caggaacggg gtctgcaacc gggacgactc
     8521 cagcagcatg ccggggtgcc aggagacgtc gtcgcgggcc tccaggaaca gcgcgtcgat
     8581 ctcggcgatc ggcgcggtca ggcaggccag acccaggttg tacggcccca ggccgatccc
     8641 gatgacgtcg tagctgtcca tccgctcctc cagtcgggaa ttctgcgtcg gcatgctcag
     8701 cccacccggc agggcacggc gggggtggac acggcgtggg tgtgcgcgta ccggccggcg
     8761 tgttcggcga tcaggtcgag cacgtacgcc acgtcgtcgg tgctggtcgc cgggttgagc
     8821 acggtgaact tgaggtactg ccggccgtcg acccgggtgc cggcgaccac ggccaggccg
     8881 gaggcggcca gcgcggaccg ggcgtgcagg ttcgccgcgt cggccagctc cgccggggtg
     8941 ccggcgggcc gccagcggaa caccacagtg ctcagcgccg acgcggtcag cacttcgaac
     9001 cgggggtcgg cggccgccag ctgccacgcc tgggcggccc ggtcacagac ctcgtcgaac
     9061 agttcgccga tggcgtcggg gcccatcacc cgcagggtca gccagagctt gagggcgtcg
     9121 aagcggcggg tggtctgcaa ggacttgtcg acctggttgg ggatgcgttc ggcgaccatc
     9181 cgggccgggt tgaggtagtc ggcgtgccag gtggcgtgcc gcagcgtatg ccggtcgcgg
     9241 accagcacgg cgctggagct gaccggctgg aagaacgact tgtggtagtc gacggtcacc
     9301 gaatcggccc gctcgatgcc gtcgagcagg tgccggcggg tcggcgagac cagcaacccg
     9361 cagccgtacg cggcgtcgac gtgcagccac acgccggagg tgccgcacac ctcggcgatc
     9421 tcgtcgagcg ggtcgatggt gccgaagtcg gtggtgccgg cggtggcgac caccgccagc
     9481 acggtcaggc cggcccgccg gcagcggctg atctcgtggc ggacggcacc ggcccgcatc
     9541 cgccggtccg ggccggtctg caccaccacg accgcgtccg gggccaggcc caacagcttg
     9601 gcggccttct gcacgctgaa gtgacccgcg gccgaggtga tgatccgcag gtggggcagc
     9661 aggatccgtc ggtcggtcgg gctcgccccg gccagggcct cctcccgggc cagcagcagc
     9721 gcgtgcaggt tggactgggt gccgccgctg gtgaacacgc cgtcggcggc cgggccgagg
     9781 ccgatccggg cggcggtcca gtcgatcagg cgtcgttcga tcagggtggc gccggcgctc
     9841 tggtcccagg tgtccatcga ggagttgacg gcgctgagca cggcctcgcc gagcagggcc
     9901 gggatgacca ccgggcagtt gaggtgggcc aggtagcgcg ggtggtggaa ccagacggcg
     9961 tcgcgcaggt acacctcgtc gagttcgtcg agggcggcgg tggtgtcgtg cagcggccgg
    10021 tccaggtcga tcgcgtccac cagcggtgcc aactgctccg ggcgtacgcc ggtgaacggg
    10081 ccggtcgcct cggcgacgcg ccgggccacc cggtcggcac cggctgtcac cgcggctcgg
    10141 tagtcgtcga ctgtgccgtc gtggaacagg tgggctcggg cggcgctcgg cggtggcgcg
    10201 gtgtgcaccg gcagggtcat ggacgtgtcc tccacgctcg gcggttcggt ttccgggcag
    10261 cctgaacccg ccgcccgcgc ggcgcgcggc gggttggcgt cgatgagggt ggtgggtgga
    10321 cgaccggcgg tcacgggtca cgcgggtcgt ccgtggcggg tcaggtcagc ttcttcgcgc
    10381 cctggatcgc cttggcgagg tcttcgagca gcggggcggc accggcgtac gagaagcggg
    10441 gcaccgcgtc ccatccggtc acctggccgg cctgcacggc gggcaactgc ttccaggtgg
    10501 gcttggcggc caggtcggcc ggttgcaggg cggtgctgcg gttgtcgagc aggatcaggt
    10561 cggccgggaa cttgccggcg ttctcccagc tgagcgcctc gaagtagtcg ccggactcca
    10621 gcttggtggg caccacgatg tcgacgccga gttcggcgaa gtacatcagg tcggtgctga
    10681 ccttcgggtt ggagacgtag aacaggtccg ggctgccgga ggcggccagc accttgatgc
    10741 cggggttggc cttgaccgcc tggcgtaccg cctcggcggc ggcctcgaag cgcgccttgg
    10801 cgtcggtgac cttcggtgcc gacaggtcgg cgccgaggga ttcggcgagt gcggcgtagc
    10861 gtgcgatcgg cttggtcatc gggacgcggg cggtggtgat ggtgaccacc ggtgcgagcg
    10921 ggaggatctt gtctttgctc tcgtccggga cgtaccagta ggcccccggg tcgtacatgt
    10981 gggtgacaag cagttccggg cgcagcgccg cgtacttctc gacgctgaac tcgccccaga
    11041 cgttgccgag gatctccacg ctctccacgt ccaggtcgcc ggcctgtgct tccttgctgc
    11101 cgtcggcctt cttcgtctcg ccgaagacgc cgaccacctc gcgcccgagt ccgaaatcga
    11161 ccagggcagc cgccgagccg gtgaaggcca ccacccgggc gggccgcgcc ggcgcggtga
    11221 ccgcctccgg gcggtcgtcg gtgaacgacc acggcccgga accgttgctg gtgctggatt
    11281 tttcagcctc gtcccgcccg cagccgacga gcacagcggt gagggcggcg gcgccaccgg
    11341 cggcgagcag gccgcgacgg gagaggcggc gggcggaaac gggatcaggc atggcgtcgt
    11401 cttccgatca gggtgtgcgg atggccatgg acagccgcgg ttaggctaac ctaacctaac
    11461 tgcctgtcaa gtcccgcacg gcgtttcgca ccgcactgga gttcacactg tccgtcaccg
    11521 agtcgcctcc cgccgcgaca ccactgcggg accaaccacc gccgcgggca ggtcatgccg
    11581 cgtcacgcgc cgccggcctc gccgtcgccg cgctggctct ggtcgtcgtg gtggtgctca
    11641 gcatcgccgt cggcgccaaa ccgatccccc tgacgcaggt gtgggcggcc ctcaccgatt
    11701 ccggtgccgt cgactacgcc gtcgtgcacg agatgcgcct gccccgaacc ctgctcgggc
    11761 tgctcgccgg cctggcgctc ggcacggccg gcgcggcggt gcaggcgct
//
