MIBiG Protein Description MIBiG Cluster MiBiG Product % ID % Coverage BLAST Score E-value
RGP42811.1 2,3-dihydroxybenzoate-AMP_ligase BGC0002696.2 NRPS:Type I 100.0 100.0 1092.0 0.0
BAH33406.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000371.5 NRPS:Type I 99.0 100.0 1078.0 0.0
QRK05499.1 (2,3-dihydroxybenzoyl)adenylate_synthase BGC0002324.3 NRPS:Type I+PKS 61.0 95.5 638.0 5.94e-227
ABF86856.1 2,3-dihydroxybenzoate-AMP_ligase BGC0002492.3 NRPS:Type I 60.0 95.3 637.0 1.11e-226
ABS75234.1 DhbE BGC0001185.5 NRPS:Type I 58.0 96.0 630.0 9.41e-224
AGK13425.1 enterobactin_synthetase_component_E_(2,3-dihydroxybenzoate-AMP_ligase) BGC0002528.3 NRPS:Type I 61.0 94.8 628.0 6.92e-223
AAZ55904.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000359.5 NRPS:Type I 60.0 96.2 622.0 1.55e-220
AEI70243.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000401.5 NRPS:Type I 59.0 95.7 621.0 3.23e-220
AAG31128.1 MxcE BGC0001345.5 NRPS:Type I 57.0 97.3 620.0 4.42e-220
CAB15188.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000309.5 NRPS:Type I 58.0 96.4 619.0 1.1e-219
CBA63660.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000368.5 NRPS:Type I 60.0 98.0 617.0 1.1e-218
OEI75574.1 (2,3-dihydroxybenzoyl)adenylate_synthase BGC0002977.1 NRPS:Type I+PKS:Type I 57.0 96.4 614.0 1.46e-217
NPC94428.1 (2,3-dihydroxybenzoyl)adenylate_synthase BGC0002695.2 NRPS:Type I 58.0 96.2 611.0 2.55e-216
WDT53594.1 (2,3-dihydroxybenzoyl)adenylate_synthase BGC0003042.1 NRPS:Type I+PKS:Type I 58.0 97.1 611.0 3.76e-216
QIE08740.1 salicylate-AMP_ligase BGC0002544.3 NRPS:Type I 57.0 95.1 586.0 9.11e-207
WP_141576284.1 AMP-binding_protein BGC0002686.2 NRPS:Type I 58.0 95.8 574.0 3.33e-202
ACU36660.1 AMP-dependent_synthetase_and_ligase BGC0000392.5 NRPS:Type I 57.0 97.1 573.0 4.69e-201
AMK48234.1 salicylate-AMP_ligase BGC0001351.3 NRPS:Type I 56.0 95.3 572.0 5.81e-201
WP_068925906.1 AMP-binding_protein BGC0002688.2 NRPS:Type I 56.0 95.7 569.0 3.22e-200
CAQ46282.1 putative_siderophore_specific_2,3-dihydroxybenzoate-AMP_ligase BGC0002689.2 NRPS:Type I 54.0 97.1 561.0 8.78e-197
MBD2892724.1 2,3-dihydroxybenzoate-AMP_ligase BGC0002718.2 NRPS:Type I 55.0 97.5 556.0 1.05e-194
EFL06871.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000300.5 NRPS:Type I 56.0 95.3 549.0 2.61e-192
ABW70812.1 PchD BGC0002475.3 NRPS:Type I 53.0 95.8 542.0 5.48e-189
AAC45927.1 2,3-dihydroxybenzoate-AMP_ligase BGC0002494.3 NRPS:Type I 53.0 96.0 541.0 7.31e-189
AAO07759.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000460.5 NRPS:Type I 53.0 96.0 533.0 8.33e-186
ABU70375.1 hypothetical_protein BGC0001890.3 NRPS:Type I 53.0 95.5 531.0 7.78e-185
AEF33098.1 3-hydroxypicolinic_acid:AMP_ligase BGC0001039.5 NRPS:Type I+PKS 50.0 97.5 524.0 4.72e-182
NII05610.1 AMP-binding_protein BGC0003005.1 NRPS:Type I 50.0 95.7 520.0 1.17e-180
ctg4_1 BGC0002017.3 NRPS:Type I 57.0 87.4 518.0 1.48e-180
ALK21567.1 2,3-dihydroxybenzoate-AMP_ligase BGC0002678.2 NRPS:Type I 53.0 96.6 519.0 3.9e-180
WFP21074.1 SrbK BGC0002912.1 NRPS:Type II 50.0 96.8 517.0 1.43e-179
AGN74880.1 3-hydroxypicolinic_acid:AMP_ligase BGC0000459.5 NRPS:Type I+PKS:Trans-AT type I 51.0 95.7 514.0 2.57e-178
AGE11892.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000366.5 NRPS:Type I 50.0 99.1 505.0 2.65e-174
CAJ45636.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000454.5 NRPS:Type I 51.0 95.8 501.0 5.21e-173
CAC17498.1 putative_AMP-binding_ligase BGC0000324.5 NRPS:Type I 49.0 98.2 488.0 5.3e-168
WP_005009579.1 AMP-binding_protein BGC0002473.3 NRPS:Type I 48.0 97.5 487.0 2.28e-167
MBE3202941.1 AMP-binding_protein BGC0002410.3 NRPS:Type I 46.0 102.9 487.0 7.23e-167
ABL70475.1 2,3-dihydroxybenzoate-AMP_ligase BGC0002493.3 NRPS:Type I 50.0 97.8 485.0 7.88e-167
BAC16758.1 probable_2,3-dihydroxybenzoate-AMP_ligase_protein BGC0002474.2 NRPS:Type I 48.0 96.0 480.0 5.29e-165
EET76301.1 putative_(2,3-dihydroxybenzoyl)adenylate_synthase BGC0002685.2 NRPS:Type I 48.0 101.4 474.0 4.42e-162
CCA53797.1 Long-chain-fatty-acid--CoA_ligase BGC0001801.5 NRPS:Type I 49.0 95.5 472.0 6.01e-162
KGA48878.1 (2,3-dihydroxybenzoyl)adenylate_synthase BGC0002413.3 NRPS:Type I 47.0 96.8 471.0 1.73e-161
CAJ34366.1 putative_3-hydroxy-quinaldate-AMP-Ligase BGC0000445.5 NRPS:Type I 47.0 95.1 468.0 2.8e-160
AAQ59159.1 2,3-dihydroxybenzoate-AMP_ligase BGC0002679.2 NRPS:Type I 49.0 96.0 467.0 5.88e-160
ABK38474.1 2,3-dihydroxybenzoate-AMP_ligase BGC0001502.4 NRPS:Type I 48.0 98.0 467.0 1.06e-159
AFB35629.1 EsmD2 BGC0000935.5 other:aminocoumarin+PKS 46.0 96.4 465.0 1.34e-158
AQZ26587.1 obafluorin_dimodular_nonribosomal_peptide_synthetase BGC0001437.5 NRPS:Type I 49.0 95.3 497.0 1.37e-158
QYA95658.1 AMP-binding_protein BGC0002676.2 NRPS:Type I 47.0 96.8 462.0 4.94e-158
MBX9445642.1 (2,3-dihydroxybenzoyl)adenylate_synthase BGC0002414.3 NRPS:Type I 49.0 98.2 461.0 2.72e-157
ACR11042.1 Enterobactin_synthetase_component_E/2,3-dihydroxybenzoate-AMP_ligase BGC0000451.5 NRPS:Type I 47.0 94.8 460.0 3.37e-157
KDQ70107.1 Triostin_synthetase_I BGC0001444.5 other:shikimate-derived 46.0 96.4 459.0 1.78e-156
CCP45172.1 Bifunctional_enzyme_MbtA:_salicyl-AMP_ligase_(SAL-AMP_ligase)_+_salicyl-S-ArCP_synthetase BGC0001021.5 NRPS:Type I+PKS 46.0 96.2 457.0 9.22e-156
ALE27504.1 3-HPA:AMP_ligase BGC0001292.5 other:other 46.0 97.7 456.0 4.31e-155
AAC73695.1 2,3-dihydroxybenzoate-AMP_ligase BGC0002476.2 NRPS:Type I 47.0 96.6 453.0 2.32e-154
EYT83445.1 Triostin_synthetase_I BGC0001213.5 PKS 44.0 95.8 450.0 2.91e-153
BAC87906.1 probable_acinetobactin_biosynthesis_protein BGC0000294.5 NRPS:Type I 44.0 98.4 446.0 2.06e-151
AVR52609.1 AMP-dependent_synthetase BGC0002443.3 PKS 46.0 96.9 445.0 4.85e-151
KJY85277.1 enterobactin_synthase_subunit_E BGC0002491.3 NRPS:Type I 46.0 98.0 445.0 5.34e-151
BAI63284.1 putative_peptide_arylation_enzyme BGC0000434.5 NRPS:Type I 46.0 94.9 441.0 1.19e-149
ACY02013.1 enterobactin_synthase_subunit_E BGC0000343.5 NRPS:Type I 46.0 96.9 441.0 1.28e-149
BAH04171.1 AMP-binding_ligase BGC0000450.5 NRPS:Type I 46.0 95.1 440.0 2.31e-149
ADB92576.1 Ccb2 BGC0001225.5 NRPS:Type I 45.0 98.2 439.0 9.1e-149
AAO56101.1 yersiniabactin_synthetase,_salicylate_ligase_component BGC0002570.2 NRPS:Type I+PKS 47.0 92.8 437.0 1.58e-148
ADE34495.1 SsfL1 BGC0000269.5 PKS:Type II+saccharide:hybrid/tailoring 47.0 97.7 437.0 4.39e-148
AAK95837.1 putative_2,3-dihydroxybenzoate-AMP-ligase_PhbE BGC0002495.2 NRPS:Type I 46.0 96.9 433.0 2.26e-146
BAE98151.1 putative_AMP-binding_ligase BGC0000339.5 NRPS:Type I 44.0 95.3 427.0 1.53e-144
CAA73130.1 Irp5_protein BGC0000467.5 NRPS:Type I 48.0 90.1 426.0 5.74e-144
CAJ87594.1 2,3-dihydroxybenzoate-AMP_ligase BGC0001055.5 NRPS:Type I+PKS 48.0 90.1 426.0 5.74e-144
AET98914.1 putative_AMP-binding_ligase BGC0000415.5 NRPS:Type I 44.0 95.1 424.0 3.46e-143
CCC55917.1 putative_acyl_CoA_ligase BGC0000973.5 NRPS:Type I+PKS:Type I 46.0 96.2 425.0 3.72e-143
ABY66018.1 CoA_ligase BGC0001008.5 PKS:Iterative type I 46.0 96.8 423.0 1.91e-142
WP_069848012.1 salicylate_synthase BGC0002472.2 NRPS:Type I 44.0 94.6 433.0 3.23e-141
AXG47413.1 salicylate_synthase BGC0002715.2 NRPS:Type I+PKS 45.0 92.4 428.0 3.08e-139
ATV95617.1 CoA_ligase BGC0001503.4 PKS 44.0 97.7 412.0 2.49e-138
AEM06018.2 hypothetical_protein BGC0000966.5 NRPS:Type I+PKS 43.0 97.8 410.0 9.65e-138
AFD30957.1 CrmE BGC0000966.5 NRPS:Type I+PKS 43.0 97.8 410.0 2.74e-136
ACN64830.1 PokM3 BGC0001061.4 PKS:Type II aromatic 44.0 97.5 406.0 6.13e-136
AAM77987.1 adenylate_ligase BGC0000112.5 PKS:Iterative type I 43.0 97.5 405.0 1.52e-135
AFV52187.1 acyl-CoA_synthetase BGC0000081.5 NRPS:Type I+PKS:Iterative type I 44.0 99.5 389.0 5.08e-129
CAG69514.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000352.5 NRPS:Type I 40.0 96.8 374.0 2.4e-123
AAO07763.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000460.5 NRPS:Type I 41.0 94.2 372.0 1.05e-122
MBN3579117.1 AMP-binding_protein BGC0002613.2 NRPS:Type I+PKS 40.0 97.3 370.0 6.7e-122
AKQ52536.1 2,3-dihydroxybenzoate-AMP_ligase BGC0002533.2 NRPS:Type I+PKS 40.0 96.9 368.0 2.43e-121
ADQ74621.1 salicylyl-AMP_ligase BGC0000921.5 other:shikimate-derived+PKS+NRPS:Type I 41.0 95.7 363.0 1.69e-119
CAP20363.1 equibactin_siderophore_biosynthetic_protein BGC0000347.5 NRPS:Type I 38.0 93.1 358.0 1.63e-117
AMB18979.1 RosA BGC0003037.1 PKS:Type I 35.0 89.0 300.0 6.52e-95
BAO66547.1 cyclohexanecarboxylate-CoA_ligase BGC0000042.5 PKS 31.0 94.2 199.0 7.63e-57
AHH25585.1 AMP-dependent_synthetase_and_ligase BGC0000957.5 NRPS:Type I+PKS 31.0 96.2 203.0 5.36e-56
MBE3200457.1 AMP-binding_protein BGC0002409.3 NRPS:Type I 33.0 95.1 195.0 3.48e-55
AWX24488.1 acyl-CoA_ligase BGC0001695.5 NRPS:Type I 33.0 88.3 189.0 3.62e-53
ADI58632.1 AsuB1 BGC0000187.5 PKS:Type II 31.0 96.6 194.0 9.08e-53
AAQ84158.1 PlmJK BGC0000123.5 PKS 30.0 102.2 192.0 4.41e-52
WP_240809958.1 long-chain_fatty_acid--CoA_ligase BGC0002686.2 NRPS:Type I 34.0 92.8 183.0 8.56e-51
BBD17745.1 AMP-ligase BGC0001918.3 NRPS:Type I+PKS 30.0 87.2 179.0 8.63e-50
MBD2892711.1 3-methylmercaptopropionyl-CoA_ligase BGC0002718.2 NRPS:Type I 32.0 92.4 164.0 6.24e-44
ABU70356.1 hypothetical_protein BGC0001890.3 NRPS:Type I 29.0 94.0 159.0 4.42e-42
OJF16272.1 AceP1 BGC0001491.3 PKS 30.0 97.5 158.0 2.11e-40
CAO85890.1 aryl-coA_ligase BGC0000110.5 PKS:Type I 30.0 94.2 149.0 2.71e-38
QIC03945.1 EncH BGC0002366.2 PKS 29.0 99.6 148.0 3.91e-38
QIZ24104.1 type_I_polyketide_synthase BGC0002540.3 PKS 31.0 95.5 150.0 1.04e-37
AAF81723.1 putative_acyl-CoA_ligase_EncH BGC0000220.4 PKS:Type II 29.0 95.5 145.0 2.53e-37
CRI73800.1 loading_module_of_NRPS-PKS BGC0001215.5 NRPS:Type I 30.0 94.8 133.0 2.5e-32
CAE17553.1 acyl_CoA_ligase BGC0000210.5 PKS:Type II+saccharide:oligosaccharide 28.0 92.2 128.0 2.28e-31
QQZ01622.1 amide_synthase BGC0002497.3 other:other 30.0 72.4 123.0 9.96e-30
NP_626687.1 acyl-CoA_synthetase BGC0000595.3 ribosomal:unmodified 29.0 90.3 118.0 3.79e-28
BBD17741.1 non-ribosomal_peptide_synthetase BGC0001918.3 NRPS:Type I+PKS 28.0 101.1 116.0 1.47e-26
CAN89633.1 putative_hybrid_non-ribosomal_peptide_synthetase/polyketide_synthase BGC0001070.5 NRPS:Type I+PKS:Type I 27.0 93.7 114.0 3.73e-26
BCK51658.1 putative_acyl-CoA_synthetase BGC0002520.2 PKS 28.0 93.1 109.0 4.22e-25
AGM05527.1 AMP-dependent_synthetase_and_ligase BGC0002098.2 PKS 27.0 90.8 109.0 6.16e-25
QIW91880.1 Ligase BGC0002543.3 NRPS:Type I 29.0 66.4 109.0 8.19e-25
APZ78679.1 nonribosomal_peptide_synthetase BGC0001417.4 NRPS:Type I+PKS:Iterative type I 26.0 94.6 109.0 1.76e-24
CAG29031.1 nonribosomal_peptide_synthetase_(modules_1_and_2) BGC0001023.5 NRPS:Type I+PKS:Type I 26.0 93.0 107.0 9.66e-24
APZ78821.1 nonribosomal_peptide_synthetase BGC0001429.4 NRPS:Type I+PKS:Iterative type I 26.0 93.0 107.0 9.66e-24
BAQ25518.1 acyl-CoA_synthetase BGC0001288.5 PKS 28.0 88.6 105.0 1.02e-23
SSTG_01180 BGC0000597.4 ribosomal:RiPP:Proteusin 30.0 77.6 104.0 1.15e-23
AAC06346.1 bacitracin_synthetase_1 BGC0000310.5 NRPS:Type I 24.0 94.4 107.0 1.36e-23
EPE34349.1 Acetyl-CoA_synthetase-like_protein BGC0001035.5 PKS+NRPS:Type I 25.0 88.6 105.0 1.43e-23
AFK57217.1 DidF BGC0000985.5 NRPS:Type I+PKS 28.0 95.1 106.0 1.97e-23
CBF76048.1 conserved_hypothetical_protein BGC0001399.4 NRPS:Type I 27.0 91.9 105.0 2.02e-23
APZ78855.1 nonribosomal_peptide_synthetase BGC0001432.4 NRPS:Type I+PKS:Iterative type I 26.0 94.6 105.0 2.99e-23
AFK57213.1 DidB BGC0000985.5 NRPS:Type I+PKS 27.0 103.6 105.0 3.57e-23
APZ78833.1 nonribosomal_peptide_synthetase BGC0001430.4 NRPS:Type I+PKS:Iterative type I 26.0 93.7 104.0 9.27e-23
APZ78845.1 nonribosomal_peptide_synthetase BGC0001431.4 NRPS:Type I+PKS:Iterative type I 26.0 94.6 103.0 2.16e-22
QOV09194.1 ClyF/NocQ BGC0002597.2 NRPS:Type I+PKS 25.0 104.0 102.0 2.74e-22
WP_123819644.1 non-ribosomal_peptide_synthetase BGC0002913.1 NRPS:Type I+PKS:Type I 28.0 102.5 102.0 3.72e-22
AYM52861.1 AMP-binding_protein BGC0001964.2 PKS 25.0 97.1 100.0 8.46e-22
CAE15497.1 BGC0002286.3 NRPS:Type I 26.0 88.3 101.0 9.38e-22
AQX77695.1 NocQ BGC0001704.3 other:other 25.0 104.0 100.0 1.12e-21
AKL71650.1 NocQ BGC0001703.3 other:other 24.0 102.7 100.0 1.12e-21
MBC5793737.1 non-ribosomal_peptide_synthetase_(depsipeptide_synthetase) BGC0002480.2 PKS+NRPS:Type I 24.0 102.7 100.0 2.61e-21
ATY69551.1 hybrid_nonribosomal_peptide_synthetase/type_I_polyketide_synthase BGC0001611.4 PKS:Type I 27.0 94.4 99.0 6.06e-21
WNZ53850.1 amino_acid_adenylation_domain-containing_protein BGC0003069.1 NRPS:Type I 25.0 90.3 99.0 6.23e-21
AAF99707.2 syringopeptin_synthetase BGC0000438.5 NRPS:Type I 27.0 96.8 98.0 1.17e-20
QBA57736.1 NRPS BGC0002377.2 NRPS:Type I 27.0 96.0 97.0 1.43e-20
ABF92798.1 AMP-binding_protein BGC0001831.3 PKS 26.0 96.9 96.0 2.65e-20
ALG65318.1 Cal18 BGC0001297.4 NRPS:Type I 28.0 94.0 94.0 1.78e-19
AVR48535.1 CusC BGC0001564.4 NRPS:Type I+PKS 23.0 94.0 93.0 3.47e-19
ESU07739.1 hypothetical_protein BGC0003072.1 NRPS:Type I 25.0 92.2 93.0 4.55e-19
AKP45400.1 CysL BGC0001413.5 NRPS:Type I 25.0 89.4 89.0 6.82e-18
MCC5036796.1 AMP-binding_protein BGC0002638.3 NRPS:Type I 29.0 64.1 86.0 2.01e-17
BCK51655.1 Adenylate-forming_enzyme BGC0002520.2 PKS 30.0 62.5 84.0 6.28e-17
BAK64635.1 putative_CoA_ligase BGC0000135.5 PKS 27.0 94.0 84.0 1.25e-16
UUG66787.1 Ktm23 BGC0002862.1 PKS:Type I 26.0 87.9 84.0 1.67e-16
BBC83957.1 nonribosomal_peptide_synthetase BGC0001636.4 NRPS:Type I 24.0 93.3 83.0 6.35e-16
AQW35047.1 Acyl-CoA_synthetase BGC0001675.5 PKS 26.0 98.2 79.0 3.65e-15
CBW54660.1 Acyl-CoA_ligase BGC0000971.5 NRPS:Type I+PKS:Type I 25.0 100.4 77.0 2.68e-14
AKC54422.1 fumosorinone_biosynthesis_polyketide_synthase BGC0001218.3 NRPS:Type I+PKS 22.0 90.8 77.0 3.79e-14
EJP62835.1 nonribosomal_peptide_synthase,_putative BGC0002203.2 NRPS:Type I+PKS+other:other 24.0 85.4 76.0 1.16e-13
AFO59871.1 ChxJ BGC0000175.5 PKS:Trans-AT type I 28.0 79.8 71.0 3.34e-12
CAJ88192.1 putative_peptide_synthetase_NRPS5-4-3 BGC0000151.5 PKS:Type I+saccharide:hybrid/tailoring 27.0 105.8 70.0 4.14e-12
AMQ36134.1 PsyC BGC0002617.2 NRPS:Type I 23.0 94.8 64.0 2.77e-10
QCF28941.1 fatty_acyl-AMP_ligase BGC0002308.2 other:other+PKS 25.0 105.6 62.0 1.09e-09
AZY91992.1 putative_fatty_acyl-AMP_ligase BGC0002022.4 PKS 25.0 88.8 59.0 7.63e-09
WP_256976120.1 AMP-binding_protein BGC0002931.1 NRPS:Type I+PKS:Type I 24.0 44.6 50.0 4.05e-06