LOCUS       BGC0002709             29001 bp    DNA     linear   CON 11-MAR-2015
DEFINITION  Fusarium graminearum PH-1 chromosome 1, whole genome shotgun
            sequence.
ACCESSION   BGC0002709
VERSION     BGC0002709
KEYWORDS    .
SOURCE      Fusarium graminearum PH-1 (Gibberella zeae PH-1)
  ORGANISM  Fusarium graminearum PH-1
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Sordariomycetes; Hypocreomycetidae; Hypocreales; Nectriaceae;
            Fusarium.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 18:16:05
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..29001
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[10307:16770]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10308..16770
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     cand_cluster    1..29001
                     /SMILES="CC(=O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..29001
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002709"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..29001
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(839..2183)
                     /locus_tag="FGSG_02320"
     mRNA            complement(839..2183)
                     /locus_tag="FGSG_02320"
                     /product="hypothetical protein"
     CDS             complement(891..2087)
                     /codon_start=1
                     /locus_tag="FGSG_02320"
                     /product="hypothetical protein"
                     /protein_id="ESU07744.1"
                     /transl_table=11
                     /translation="MSSTDPLLRRVENYRESCDNCAKSKVRCGKEQPWCQRCERRGQVC
                     SYSPSQRSRKRTLDAAHPESDQRNGTPPFTAISSASSVAAVSTGFSSMLSQADSWGTCP
                     DLVELLTSGSSSESLTPDNNHLVWLSDMESIAGDSNISKSMERMDVFPYPKSIASSAAG
                     VVNGSGAGADSMGRRSTCPLQNKQHCEADLISALAKPELPSLSCWGNPKASQNLGTILT
                     ASRATLKCVTTAMSCTCTPNDNVALLATAVLLRILSWYHIVLKNCNGPNDTSAATIDDH
                     TSPTPSNDGKDTERSVSRDTNVSQDGSEPSSLIMPPMTIGAYELDSENRERMIGHIMLS
                     ELGKMGNLLSDFSKKFCDPQSTMLGNDNRSQLFLALEMLIRNKHMATVLDVRKKLEVK"
     CDS             join(3397..4432,4526..5010)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138:FAD linked oxidase domain protein (Score: 283;
                     E-value: 1.1e-85)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="FGSG_02321"
                     /product="hypothetical protein"
                     /protein_id="ESU07745.1"
                     /transl_table=11
                     /translation="MINSFSLFAHITPIIRSSLHSRYSVISSRKAMSSLAAAPYRHVMM
                     PFSPAQDAQVHGNSALTKLTDAIPDLKIYTRSSPHYESLRGVYNKLITAQPLAICRPTS
                     VAQVQAIVKTVSGLGIPLGVRGGGHDVFGRGCIADSVTIDMRELDTQELSQDKKTVKVG
                     GGITSKNLVGFLGSHNLCTSNGFAGEAGWTSWASWGGYGPLGDYVGLGVDNIVGAKIVT
                     ASGDVVDAKGDSELLWALRGGGGNFGVIAETDVRVYPMSTIQAGFIVYPWPETADVLLR
                     LQALLDSGVPDKLCLQAGFTKGEWGLGMAITYIWPEAETIGPESEEWLQKLKGLGTCIV
                     DTVAETTFEAFQASISSAISNPVNVTSRHISISKFTSDTLNQLIGACESMPAEADCSIT
                     CTILHGKAAQANVLSAFGTRRPHIMLHINAVTEEAAHEHVAIAWADRLVDGVEATGDSI
                     GSTYVSFMESDKDPKGCYGENWERLKAVKKEVDPNDVFRFVHGRIPAA"
     gene            <3397..5149
                     /locus_tag="FGSG_02321"
     mRNA            join(<3397..4432,4526..5149)
                     /locus_tag="FGSG_02321"
                     /product="hypothetical protein"
     gene            complement(5557..7558)
                     /locus_tag="FGSG_02322"
     mRNA            complement(join(5557..6716,6780..7558))
                     /locus_tag="FGSG_02322"
                     /product="hypothetical protein"
     CDS             complement(join(5711..6716,6780..7408))
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 347.6; E-value:
                     1.3e-105)"
                     /gene_kind="transport"
                     /locus_tag="FGSG_02322"
                     /product="hypothetical protein"
                     /protein_id="ESU07746.1"
                     /transl_table=11
                     /translation="MTDNTDMEKLDRATTPTPIPNEAPPTSEPSESKPEEAEDESKYPH
                     GLKLAAIILSNMVAMFLVALDRTIIATAIPRITDDFNALGDISWYASAYLITSSATQLL
                     WGRIFTFYPTKTVYLVAIFFFELGSLLCGVAPNSVAFIIGRAIAGAGSAGIYSGSTILI
                     TTVTPLSKRAGYVGMMGAVFGIASVIAPLIGGAFTDHVTWRWCFYINLPVGGAAVACLI
                     LLFPKFPVNEPVSVKQQIKQLDPWGNLVFLPGVICLILALQWGGEKYAWDSGRIVALLV
                     LACVLLLVFIGIQIWQQENATVPPRLFKIRNVWLGTIFAFCLGSVLIVFLIALPIWFQG
                     IRGTDAITSGIDTLPLVLSLVFGAIVSGGVINGVGWFNPVFFSSVIFMSVGGGLITTFV
                     VDTPTRTWIGYQIILGLGIGQGMQLASLGTQVAVKQSDVPTGVSLMFFAQSLGGSVLVC
                     VAQAVFNNELRSRLTSFDGIDVARIIGTGATQLRHVIPADRLAEVLVEYNAALRSYFYV
                     GLAAACFAVLPSLGIEWKNVKGQEFVH"
     gene            <7967..>10143
                     /locus_tag="FGSG_02323"
     mRNA            join(<7967..8217,8272..8302,8358..8816,8872..>10143)
                     /locus_tag="FGSG_02323"
                     /product="hypothetical protein"
     CDS             join(7967..8217,8272..8302,8358..8816,8872..10143)
                     /codon_start=1
                     /locus_tag="FGSG_02323"
                     /product="hypothetical protein"
                     /protein_id="ESU07747.1"
                     /transl_table=11
                     /translation="MTEAKLTRGHSCVPCQHRKIRCNGQTPCAYCIRTGKECVRMRVSP
                     SHSRNARLNHRRLTAAQTGSPSGDGQVIVSGDQRRYVEDNKLWKSLGDEMQGKDVSPDP
                     ERPPLRTRTDTPSTEVNLIFSHQRPTSISVKYPSAVHSFQLWQVFISNVHPLTKILHGP
                     TVQKDILETFSEPTSTPGPTEALIFAIYLVAVVSLTDAECRSRFGEPRKDLLARYCNAT
                     EVALSKADFLRSTDLRVLQAFTLHLLSLRHICDHDILWLLTGLATRMGQRMGLHRESSL
                     KDLPPFEAELRRRVWWQIVILDGRASQLTGASMNPNMQLYGDTQQPINLSDADLVPSAS
                     TIPQPSPITTDMLFCKVRIEIGVWMIEQKCLLGSESESSTTGKAKFFKAIDELERHIEE
                     KYLANMDKELPLNLLTAYLARSAVCQLRLSVYHPIHRPERASDLSAEQIDMLLENSLEV
                     IRYDILSHSTPALQCYLWHIANFFPFETFVLLISTLSGRPAGQVVDTAWEVIDQVYEHH
                     PSFVSDTSDPLYWALGNITLKAWDQRVTSARTRGITVPRELPCIANLVHARATMARASS
                     QQPSTTDVSGPATPQSLLLAQEAPVDYLGGLGTTNELASQTDLGMATGEELLGMMKGVD
                     VDWDFWQQLLDGNGHDARARDDQETFYFSSFINKA"
     gene            complement(<10308..>16770)
                     /locus_tag="FGSG_02324"
     mRNA            complement(join(<10308..11723,11772..14779,14843..15070,
                     15119..16100,16155..16449,16496..>16770))
                     /locus_tag="FGSG_02324"
                     /product="hypothetical protein"
     CDS             complement(join(10308..11723,11772..14779,14843..15070,
                     15119..16100,16155..16449,16496..16770))
                     /NRPS_PKS="Domain: SAT (3-241). E-value: 6.7e-74. Score:
                     240.3. Matches aSDomain: nrpspksdomains_FGSG_02324_SAT.1"
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (375-810). E-value:
                     1.8e-151. Score: 496.7. Matches aSDomain:
                     nrpspksdomains_FGSG_02324_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (912-1213). E-value: 1e-81.
                     Score: 266.4. Matches aSDomain:
                     nrpspksdomains_FGSG_02324_PKS_AT.1"
                     /NRPS_PKS="Domain: PT (1292-1610). E-value: 4.2e-103.
                     Score: 336.8. Matches aSDomain:
                     nrpspksdomains_FGSG_02324_PT.1"
                     /NRPS_PKS="Domain: PP-binding (1668-1730). E-value:
                     1.4e-12. Score: 39.9. Matches aSDomain:
                     nrpspksdomains_FGSG_02324_PP-binding.1"
                     /NRPS_PKS="Domain: Thioesterase (1801-2049). E-value:
                     1.3e-24. Score: 79.7. Matches aSDomain:
                     nrpspksdomains_FGSG_02324_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021:malonyl CoA-acyl carrier protein transacylase
                     (Score: 147.6; E-value: 9.6e-45)"
                     /gene_kind="biosynthetic"
                     /locus_tag="FGSG_02324"
                     /product="hypothetical protein"
                     /protein_id="ESU07748.1"
                     /sec_met_domain="itr_KS (E-value: 5.1e-163, bitscore:
                     532.2, seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 2e-82, bitscore: 266.4,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.8e-13, bitscore:
                     39.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVFVFGDQSTRFAPPLKDLLLKGNSPYLTHFVKQVHALLRREIS
                     SLPAVQQKLFPNFADIQELVSKSDWGSGNPALTSALACFYHLCSFIHFYDGQGRTFPSE
                     NSRIIGLCVGSLAAAAVSCSTSLSELVSAGVDAVRVALHVGLRVWRTTSLFDVPDRPSA
                     TWSIIVPEAVLPRESAQDRLDSFIIEMGLARSSVPYISSVAHHNMTISGPPSVLEKFIH
                     SISTSPKDSLPVPIYAPYHASHLYSMDDVDEVLSLSAPSFASESIIPLISSSSGDELQP
                     LKYADLLRCCVSDMLIQPLDLTKVSQAVAQLLEVSSSTRAIIKPIATSVSNSLVSALEP
                     TLAERCAVDNSMGPKASTSHSSAETQTESSSKNSKIAIVAMSGRFPDAADLGEFWDLLY
                     KGRDVHRQIPEDRFNAELHYDATGRRKNTSKVMNGCFIKEPGLFDARFFNMSPKEAEQS
                     DPGQRMALETAYEALEMAGIVPDRTPSTQRDRVGVFYGMTSDDWREVNSGQNVDTYFIP
                     GGNRAFTPGRLNYFFKFSGPSASVDTACSSSLAALHLACNSLWRNDCDTAIAGGTNVMT
                     NPDNFAGLDRGHFLSRTGNCNTFDDGADGYCRADGVGTIILKRLEDAEADNDPILGVIL
                     GAYTNHSAEAVSITRPHAGAQEYIFSKLLRESGTDPYNVSYIEMHGTGTQAGDATEMTS
                     VLKTFAPTSGFGGRLPHQNLHLGSVKANVGHGESASGIIALIKTLLMMEKNMIPPHCGI
                     KTKINHHFPTDLTQRNVHIAKVPTSWTRSGQANPRIAFVNNFSAAGGNSAVLLQDAPRP
                     SVVSDVTDPRSSHVVTMSARSADSLRKNLANLKELVEGQGDSEVDFLSKLSYTTTARRM
                     HHQFRASVTAQTREQLLKGLDSAIERQDVKRIPAAAPSVGFVFSGQGAQYRGMGKEYFT
                     SFTAFRSEIMSYDSIAQAQGFPSILPLIRGEVEADSLSPVEIQLGLTCLQMALAKLWKS
                     FGVEPGFVLGHSLGHYAALHVAGVLSANDTIYLTGIRAQLLVDKCQAGTHSMLAVRASL
                     LQIQQFLDANIHEVACVNGPREVVISGRVADIDQLVGLLSADNIKATRVKVPFAFHSAQ
                     VDPILSDLDTAASRVTFHSPQIPVLCALDSSVISPGNHGVIGPLHLQRHCRETVNFEGA
                     LHAAEREKIINKTSTLWIEIGPHVVCSTFLKSSLGPSTPTIASLRRNDDCWKVLADGLS
                     SLYSSGLTIDWNEYHRDFKASHQVLRLPCYSWEHKNYWIQYKYDWSLTKGDPPIAPNSS
                     VEAVSALSTPSVQKILQETSLDQVLTIVAETDLASPLLSEVAQGHRVNGVKVCTSSVYA
                     DVGLTLGKYILDNYRTDLEGYAVDVHGIEVHKPLLLKEDMNGTPQATPFRIEVRYPIQS
                     TTALMSISTTGPNGQHIKHANCELRLEHPSQWEAEWDRQAYLINRSVNYLLQRSAQGLD
                     SMLATGMVYKVFSSLVDYADGYKGLQEVVLHSQELEGTAKVRFQTPSGGFVCNPMWIDS
                     CGQTTGFMMNCHQTTPNDYVYVNHGWKSMRLAKAFREDGTYRTYIRMRPIDSTKFAGDL
                     YILDEDDTVVGVYGDITFQGLPRRVLNTVLPSANAVPVDAPMGRRDVPPSRMDVPPVRS
                     GEGPPTSAPTQQAIALPFAADTSMDSRLRPLLRILSEEIGLGLDVLSDDELDFADHGVD
                     SLLSLTITGRMREELGLDVESTAFMNCPTLGSFKLFLGLVDQDNKSSSGSDGSGRSSPA
                     PGIESGATTPPMSEEDQDKIVSSHSLHQFQASSTLLQGSPSKARSTLFLLPDGSGSATS
                     YASLPPISPDGDVAVYGLNCPWLKDASYLVEFGLKGLTELYVNEILRRKPQGPYNLGGW
                     SAGGICAYEAALILTRAGHQVDRLILIDSPNPVGLEKLPPRLYDFLNSQNVFGSDNPHS
                     TAGTSVKAPEWLLAHFLAFIDALDAYVAVPWDSGLVGLASPLPAPPQTYMLWAEDGVCK
                     DSDSARPEYRDDDPREMRWLLENRTNFGPNGWEALLGGKEGLFMDRIAEANHFSMLKRG
                     RNAEYVSAFLARALDN"
     aSDomain        complement(10365..11108)
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FGSG_02324_Thioesterase.1"
                     /evalue="1.30E-24"
                     /label="FGSG_02324_Thioesterase.1"
                     /locus_tag="FGSG_02324"
                     /protein_end="2049"
                     /protein_start="1801"
                     /score="79.7"
                     /tool="antismash"
                     /translation="TLFLLPDGSGSATSYASLPPISPDGDVAVYGLNCPWLKDASYLVE
                     FGLKGLTELYVNEILRRKPQGPYNLGGWSAGGICAYEAALILTRAGHQVDRLILIDSPN
                     PVGLEKLPPRLYDFLNSQNVFGSDNPHSTAGTSVKAPEWLLAHFLAFIDALDAYVAVPW
                     DSGLVGLASPLPAPPQTYMLWAEDGVCKDSDSARPEYRDDDPREMRWLLENRTNFGPNG
                     WEALLGGKEGLFMDRIAEANHFSMLK"
     aSModule        complement(10365..15545)
                     /complete
                     /domains="nrpspksdomains_FGSG_02324_PKS_KS.1"
                     /domains="nrpspksdomains_FGSG_02324_PKS_AT.1"
                     /domains="nrpspksdomains_FGSG_02324_PT.1"
                     /domains="nrpspksdomains_FGSG_02324_PP-binding.1"
                     /domains="nrpspksdomains_FGSG_02324_Thioesterase.1"
                     /final_module
                     /iterative
                     /locus_tags="FGSG_02324"
                     /monomer_pairings="mal -> mal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       complement(10854..10919)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FGSG_02324_0009"
                     /evalue="8.10E-12"
                     /label="NRPS-te1"
                     /locus_tag="FGSG_02324"
                     /protein_end="1886"
                     /protein_start="1864"
                     /score="37.5"
                     /tool="antismash"
                     /translation="PQGPYNLGGWSAGGICAYEAAL"
     aSDomain        complement(11322..11507)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FGSG_02324_PP-binding.1"
                     /evalue="1.40E-12"
                     /label="FGSG_02324_PP-binding.1"
                     /locus_tag="FGSG_02324"
                     /protein_end="1730"
                     /protein_start="1668"
                     /score="39.9"
                     /tool="antismash"
                     /translation="LLRILSEEIGLGLDVLSDDELDFADHGVDSLLSLTITGRMREELG
                     LDVESTAFMNCPTLGSF"
     aSDomain        complement(join(11682..11723,11772..12683))
                     /aSDomain="PT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FGSG_02324_PT.1"
                     /evalue="4.20E-103"
                     /label="FGSG_02324_PT.1"
                     /locus_tag="FGSG_02324"
                     /protein_end="1610"
                     /protein_start="1292"
                     /score="336.8"
                     /tool="antismash"
                     /translation="TPSVQKILQETSLDQVLTIVAETDLASPLLSEVAQGHRVNGVKVC
                     TSSVYADVGLTLGKYILDNYRTDLEGYAVDVHGIEVHKPLLLKEDMNGTPQATPFRIEV
                     RYPIQSTTALMSISTTGPNGQHIKHANCELRLEHPSQWEAEWDRQAYLINRSVNYLLQR
                     SAQGLDSMLATGMVYKVFSSLVDYADGYKGLQEVVLHSQELEGTAKVRFQTPSGGFVCN
                     PMWIDSCGQTTGFMMNCHQTTPNDYVYVNHGWKSMRLAKAFREDGTYRTYIRMRPIDST
                     KFAGDLYILDEDDTVVGVYGDITFQGLPRRVLNTVLP"
     aSDomain        complement(12921..13823)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FGSG_02324_PKS_AT.1"
                     /evalue="1.00E-81"
                     /label="FGSG_02324_PKS_AT.1"
                     /locus_tag="FGSG_02324"
                     /protein_end="1213"
                     /protein_start="912"
                     /score="266.4"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="VFSGQGAQYRGMGKEYFTSFTAFRSEIMSYDSIAQAQGFPSILPL
                     IRGEVEADSLSPVEIQLGLTCLQMALAKLWKSFGVEPGFVLGHSLGHYAALHVAGVLSA
                     NDTIYLTGIRAQLLVDKCQAGTHSMLAVRASLLQIQQFLDANIHEVACVNGPREVVISG
                     RVADIDQLVGLLSADNIKATRVKVPFAFHSAQVDPILSDLDTAASRVTFHSPQIPVLCA
                     LDSSVISPGNHGVIGPLHLQRHCRETVNFEGALHAAEREKIINKTSTLWIEIGPHVVCS
                     TFLKSSLGPSTPTIASLRRN"
     CDS_motif       complement(13335..13373)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FGSG_02324_0008"
                     /evalue="2.90E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="FGSG_02324"
                     /protein_end="1075"
                     /protein_start="1062"
                     /score="11.0"
                     /tool="antismash"
                     /translation="ACVNGPREVVISG"
     CDS_motif       complement(13473..13589)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FGSG_02324_0007"
                     /evalue="3.20E-12"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="FGSG_02324"
                     /protein_end="1029"
                     /protein_start="990"
                     /score="38.5"
                     /tool="antismash"
                     /translation="GVEPGFVLGHSLGHYAALHVAGVLSANDTIYLTGIRAQL"
     CDS_motif       complement(13773..13820)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FGSG_02324_0006"
                     /evalue="1.20E-04"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="FGSG_02324"
                     /protein_end="929"
                     /protein_start="913"
                     /score="14.8"
                     /tool="antismash"
                     /translation="FSGQGAQYRGMGKEYF"
     aSDomain        complement(join(14130..14779,14843..15070,15119..15545))
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FGSG_02324_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.80E-151"
                     /label="FGSG_02324_PKS_KS.1"
                     /locus_tag="FGSG_02324"
                     /protein_end="810"
                     /protein_start="375"
                     /score="496.7"
                     /tool="antismash"
                     /translation="IAIVAMSGRFPDAADLGEFWDLLYKGRDVHRQIPEDRFNAELHYD
                     ATGRRKNTSKVMNGCFIKEPGLFDARFFNMSPKEAEQSDPGQRMALETAYEALEMAGIV
                     PDRTPSTQRDRVGVFYGMTSDDWREVNSGQNVDTYFIPGGNRAFTPGRLNYFFKFSGPS
                     ASVDTACSSSLAALHLACNSLWRNDCDTAIAGGTNVMTNPDNFAGLDRGHFLSRTGNCN
                     TFDDGADGYCRADGVGTIILKRLEDAEADNDPILGVILGAYTNHSAEAVSITRPHAGAQ
                     EYIFSKLLRESGTDPYNVSYIEMHGTGTQAGDATEMTSVLKTFAPTSGFGGRLPHQNLH
                     LGSVKANVGHGESASGIIALIKTLLMMEKNMIPPHCGIKTKINHHFPTDLTQRNVHIAK
                     VPTSWTRSGQANPRIAFVNNFSAAGGNSAVLLQDAP"
     CDS_motif       complement(14367..14411)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FGSG_02324_0005"
                     /evalue="5.00E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="FGSG_02324"
                     /protein_end="731"
                     /protein_start="716"
                     /score="9.7"
                     /tool="antismash"
                     /translation="GSVKANVGHGESASG"
     CDS_motif       complement(14487..14534)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FGSG_02324_0004"
                     /evalue="8.00E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="FGSG_02324"
                     /protein_end="691"
                     /protein_start="675"
                     /score="11.8"
                     /tool="antismash"
                     /translation="YIEMHGTGTQAGDATE"
     CDS_motif       complement(14727..14765)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FGSG_02324_0003"
                     /evalue="3.50E-03"
                     /label="PKSI-KS_m4"
                     /locus_tag="FGSG_02324"
                     /protein_end="611"
                     /protein_start="598"
                     /score="10.7"
                     /tool="antismash"
                     /translation="FDDGADGYCRADG"
     CDS_motif       complement(14970..15017)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FGSG_02324_0002"
                     /evalue="1.70E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="FGSG_02324"
                     /protein_end="551"
                     /protein_start="535"
                     /score="17.0"
                     /tool="antismash"
                     /translation="GPSASVDTACSSSLAA"
     aSDomain        complement(join(15948..16100,16155..16449,16496..16761))
                     /aSDomain="SAT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FGSG_02324_SAT.1"
                     /evalue="6.70E-74"
                     /label="FGSG_02324_SAT.1"
                     /locus_tag="FGSG_02324"
                     /protein_end="241"
                     /protein_start="3"
                     /score="240.3"
                     /tool="antismash"
                     /translation="FVFGDQSTRFAPPLKDLLLKGNSPYLTHFVKQVHALLRREISSLP
                     AVQQKLFPNFADIQELVSKSDWGSGNPALTSALACFYHLCSFIHFYDGQGRTFPSENSR
                     IIGLCVGSLAAAAVSCSTSLSELVSAGVDAVRVALHVGLRVWRTTSLFDVPDRPSATWS
                     IIVPEAVLPRESAQDRLDSFIIEMGLARSSVPYISSVAHHNMTISGPPSVLEKFIHSIS
                     TSPKDSLPVPIYAPYH"
     CDS_motif       complement(16341..16403)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FGSG_02324_0001"
                     /evalue="3.90E+00"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="FGSG_02324"
                     /protein_end="128"
                     /protein_start="107"
                     /score="0.8"
                     /tool="antismash"
                     /translation="IIGLCVGSLAAAAVSCSTSLS"
     gene            17268..17879
                     /locus_tag="FGSG_02325"
     mRNA            join(17268..17692,17748..17879)
                     /locus_tag="FGSG_02325"
                     /product="hypothetical protein"
     CDS             join(17295..17692,17748..17808)
                     /codon_start=1
                     /locus_tag="FGSG_02325"
                     /product="hypothetical protein"
                     /protein_id="ESU07749.1"
                     /transl_table=11
                     /translation="MSPHSDTQETSHEATVTGQPDTLVCLTITAYKKPSLSEKEYRHHM
                     TKVHAKLVSPLMEEYGIVRYTMTHNTKETRPMLYQLYDPQFSNQSDYDCIVQFIFKDIK
                     DFLRMKADPRFLEKVAPDHVNFADTKRSTMTVGYYEEFVNDGKVVPKD"
     CDS             complement(join(18128..18673,18731..19246,19301..19558))
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 226.2; E-value:
                     1.1e-68)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="FGSG_02326"
                     /product="hypothetical protein"
                     /protein_id="ESU07750.1"
                     /transl_table=11
                     /translation="MGSISSPSLIIDLANAVSSAAKNLDTQLQSQGFPQPSFEADGPTY
                     VVPKDAPKAAHEARVATAEAALKLFNLVSGPSELLPNMTASYHTIFALQWLHHFDVFSH
                     IPLDGSLSYEKLATKANVPESLLKSVARMAMTSNILAEPTTGQVAHSANSAMFVKFPNM
                     RDWASYMFTASIPTAAAMVQATEKWPGSVKKTETAYNIAFNHDLPFFDHLSQSPVMTKQ
                     FSGYMRSVTDGQGMDLSHLVNGFDWASLPDKSLIVDIGGSAGHASYALAAAYPHLRFEV
                     QDLDTVVNGEKAAKEHEEAVSKHVIGTDNRVTFKAHNFFEAQPTKDATVYMLRMIIHDW
                     PDAEAKTILGNLVPALESAKATLLIMDTVLPSPGSIPSVRERVIRTRDLTMRQVFNAKE
                     RGVDDWEAILRETDSRLTLKNLRQPEGSNMCLLTISLQDD"
     gene            complement(<18128..19619)
                     /locus_tag="FGSG_02326"
     mRNA            complement(join(<18128..18673,18731..19246,19301..19619))
                     /locus_tag="FGSG_02326"
                     /product="hypothetical protein"
     gene            <20061..>21853
                     /locus_tag="FGSG_02327"
     mRNA            join(<20061..20223,20277..20336,20391..20685,20735..20861,
                     20915..>21853)
                     /locus_tag="FGSG_02327"
                     /product="hypothetical protein"
     CDS             join(20061..20223,20277..20336,20391..20685,20735..20861,
                     20915..21853)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FMO-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="other (smcogs) SMCOG1092:hypothetical
                     protein (Score: 337; E-value: 3.8e-102)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="FGSG_02327"
                     /product="hypothetical protein"
                     /protein_id="ESU07751.1"
                     /sec_met_domain="FMO-like (E-value: 1.7e-64, bitscore:
                     207.5, seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.1e-10, bitscore:
                     29.8, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPNPTVAIVGLGALGLVTLKNLREEGFDAVGLDRNDYVGGLWHFE
                     EGNKLTVMRSTLSNGSKQRGCFTDFPFPEDSPDFIPAEGIDRYLKDYAKHFGLLEHCRL
                     RTSFHGARYDEKKQQWRLSLSTPDAPEPHFEWFDKVVFAMGADQIPSRPKIEGIEKFKG
                     HVEHSMSFKNPETLAGKRVMVLGFGNTAADMATELAPIADQVYLAHRHGAIIVPRWVKG
                     KPVDHVRTYRKYVILNLMNRYTPGLWEKTMNSVIGKLVHNTFDLKPEWRFDPAPSITNQ
                     RPLVNDELIPSLEKGSIISTHGLARVIDENTVETSDGQRYEVDAILFCTGFTVDYSVVG
                     MDADPCRATTTDWQKSRGFTGRPLPRLYQNIFSLDHPETLAFIGHLSFMNPAFFMFDLA
                     SMAVAQLWKDPSGFPSKAEMNKQVDDQHAWVIDLAKKGPVTPSIVKASEWMEWVDRVIG
                     SGLPEHLGYTMKGWNFWMRDRKFCNIMMDGLLSPHAYRVFPGKRKAWPGARDAIIAMNA
                     DREARFGPMD"
     gene            complement(22188..>24452)
                     /locus_tag="FGSG_02328"
     mRNA            complement(join(22188..23521,23570..23695,23753..23923,
                     23975..24163,24199..>24452))
                     /locus_tag="FGSG_02328"
                     /product="hypothetical protein"
     CDS             complement(join(22228..23521,23570..23695,23753..23923,
                     23975..24163,24199..24452))
                     /codon_start=1
                     /locus_tag="FGSG_02328"
                     /product="hypothetical protein"
                     /protein_id="ESU07752.1"
                     /transl_table=11
                     /translation="MLTSPRLILLLLAWVFSALVASALVKKDWTITWEPGAPNGQERNM
                     IKINNQFPGPTILCDEDDDIEVTVHNKMPFNTTVHWHGLERVNCVRMMGTPWSDGTPGM
                     SQKPIEMGQSFIYRFKASPAGTHWYHSHSRATVLDGLYGPIFIRRKPDAPAPWHLISKE
                     QADIDAMSRAVIDPKLVMVSDWTRFMSWEYMAAEESSGMAIFCSDSILVNGKGSLYCPD
                     VDVLINHTSTYMKYGLYPRQVNDKGCFPFMRSTQGPYLTTGKPETIPLHLQHGCTPAEG
                     TNETIEVDPADQWASLNFIGGATFKTIVFSVDEHDMWVYEVDGHYIVPQRVNTVHMYAG
                     ERYAVMIKLDKTPKDYTIRVADSGLTQVISAFATLRYKGGIQGSDSVGVIDYGGQNSTK
                     DGSVITLDREHLPPYPPNPPARKADAMHVLSTHRWKSAWQYTMSGHGMYEEDRSAYGPL
                     LYDPHSADAMDEGLVIRTKNGSWVDLVLQVGSLPGQPQEFPHMMHKHTGKTWQIGSGMG
                     IWNYSSVEEAIAAEPHNFDLDTPKWRDTFVTSFDGSAWIVLRYQVTNPGPWLFHCHIET
                     HLAGGMAIAILDGIDVWPQIPAEYGPDQRGFMPGTLPELESGGKQGTVDKQCPLLAVSP
                     SGGPKKDSGETSASDSRWETLIRGLIQVLQGWLSDEASSRSS"
     gene            <24806..>26086
                     /locus_tag="FGSG_02329"
     mRNA            join(<24806..25714,25772..>26086)
                     /locus_tag="FGSG_02329"
                     /product="hypothetical protein"
     CDS             join(24806..25714,25772..26086)
                     /codon_start=1
                     /locus_tag="FGSG_02329"
                     /product="hypothetical protein"
                     /protein_id="ESU07753.1"
                     /transl_table=11
                     /translation="MSKQKPSLWRALRALSFIISIPLLIQYLVLKWYSTSQNTPTPVFH
                     EPNHETNLTVWEVLSNDDRVSKFVDVIGKLPDIVRGLSAPQARFTVYAPVNEAFDSFYF
                     PPDPPPFFGLFIAGCHMGPGPVPAERLPSMGTVSSFVNGDIFFTYKQRISVQKDKSGLT
                     LNRAARVLPVNASQSIAVNGFVHHIDTVLELPNSTAHALRTRPELSKLRRGLEATKLSE
                     SIYDTNAHVSQTIFAPTNAAFDRLGKTATKFLFSHGGRPYLRALLKYHVVANKTLFSDS
                     YWPHGGAKLMDLSLIPNKDSHQFDLPTLHNNLTLQVESRKIHKKWHLNVLKDQVAEGKS
                     HDSIPVSMPDVILMDGVMHFIDSILLPPAKSEQRKTSWLSRLKSSLGHNKQSIEDLVTL
                     LGPYIDEP"
     gene            complement(<26341..>28246)
                     /locus_tag="FGSG_02330"
     mRNA            complement(join(<26341..26971,27022..27950,27998..>28246))
                     /locus_tag="FGSG_02330"
                     /product="hypothetical protein"
     CDS             complement(join(26341..26971,27022..27950,27998..28246))
                     /codon_start=1
                     /locus_tag="FGSG_02330"
                     /product="hypothetical protein"
                     /protein_id="ESU07754.1"
                     /transl_table=11
                     /translation="MLFRFLALLPFVAGAFAEYKVHDDTFKPDYVLEATLDDIKINCVS
                     RSSIVFNGTSPGPTIYLQEEQTTWIRVYNKIPDNNVTVHWHGLSQRAAPFSDGTPLVSQ
                     WPIPAGQFFDYEIRPEIGDAGSYFYHSHVGFQIVTAFGALIVRDARKPEYKYDGDIPLL
                     VGDNYAAEDEVIEQGLLADPFKWSGEPQAITIQGNSGNKSFYEAPDSSCMPHVVHVDPG
                     KTYRLRFISATALSMIKLGIEDHENLTVIEADGSYTKPAKIDHVQVSPGQRYSYLMKTK
                     TSKEVCGGDKSQYWIRYESRDRPKVISGYALLKYRCDKNQKLPKSLPETSPIELSNSTA
                     DYLEYALEGLSEKNNQAFPKLSEVTRTVVIQINQILTTGAYVNGTLNGTVAWAQNGLPW
                     KENVQAERRQVPYLIQIYENGTTPNYTLALEHHGFDPETKAFPAKVGEVLDIVWENNNG
                     PTGGWDYHPMHVHGYHVYDLGSGNGTYNATENEAHFENFTPVLRDTTNLYRYAVKGVPH
                     HTAGWRAWRIRITEENIGAWMMHCHIAQHQVMGMATVWVFGDAEQIRGKFPAPPYTQGY
                     LTYGGSAYGTEDDQPWVNEYYSDKNN"
ORIGIN
        1 agaatgtcag ccacaacgtc aacgaataga gaatataacc caatgatacc ttgttgaact
       61 ttatatcgtt gtcttttgtt gttgtatcaa aggggttatc ttgttaaggt tgctgctctc
      121 tttggagatg aaagcaccgc caaattataa cccaatgatg gcatcagaag ccacgttacg
      181 ccaacaatgg gaaattgacc gagtctttta tactgaccct ggtattggaa actttctccg
      241 aggtctagaa ttagagactg aaaggtgttt gtctaagtga ttatgacact gattgttgca
      301 gattatagta ggccttgaac gagtccgatg tctcacaact cctcaagacc tctacagctg
      361 atcaaaactg cctctactat cagtatgact tccgaggcta ccaaaggcgg ccagaatttc
      421 gatacgtaag gcgtgcagcc cttctattgg cgaaaaggcc tggatgccaa ggagggaaaa
      481 catcctggcc tccaaaccaa ctccccgatg cttagaaggg ttgaagcccc gaggtcatgc
      541 agccttctca aggaacttgg gagtagggcc atgggcggca agaactcggt agctgtgtgg
      601 tggaatctgg atgcctgcac ccacctaagg gagttttggt tgatacgggg ctgagctctc
      661 ggagaccgta aaagcaggca cctgtcatgg atacgaagtc actccagttt cgtctcagga
      721 taccacgctg ttgatcatcc agaatatttc tagatggtct ataagatatg attacaagct
      781 gccgcgagaa catacgaaaa tcactcaact cccagagtaa ccatcattaa cagcaaccat
      841 gttgatttat gagtttgatt tcacttcttt agggtatagt tattatctat ctacttgacc
      901 tcgagcttct ttcgtacatc caggacagtt gccatgtgtt tattccgaat caacatttcc
      961 aaagcgagaa acagctgact cctattgtcg ttacccaaca tggttgactg ggggtcacag
     1021 aacttctttg aaaaatcact cagcaagttc cccatcttac ccaactcgct gagcatgatg
     1081 tgcccaatca tgcgctctct attctcagaa tctagctcat atgctccaat cgtcatcggc
     1141 ggcatgatga gacttgacgg ctcacttccg tcttgtgaca catttgtgtc ccgtgacact
     1201 gaccgctcgg tgtcctttcc atcattagat ggtgtagggc tggtgtgatc gtcgatcgtt
     1261 gccgcactgg tatcgttggg accattgcag tttttcagca cgatgtggta ccaggataag
     1321 atgcgcagca acactgctgt ggccagcaat gcgacgttgt cattcggggt gcatgtgcat
     1381 gacatagcag tggtgacaca cttgagtgtt gcacggctgg ctgtcaggat ggttccgaga
     1441 ttttgggacg ctttggggtt accccagcat gacagggaag gaagttcggg ttttgccagt
     1501 gcggatataa gatcagcctc gcagtgctgc ttgttttgga gtgggcatgt tgatcgtcgt
     1561 cccatgctgt cggcaccagc tccactgcca ttgaccaccc ctgctgccga tgaggcgatg
     1621 ctctttggat atgggaagac atccattctt tccatactct tgctgatatt gctgtcgcca
     1681 gcaattgatt ccatatctga caaccacacc agatggttat tgtctggtgt gagagactca
     1741 gagctactgc cactggtcaa cagctcgaca aggtcgggac aggtgcccca gctgtcagct
     1801 tggctaagca ttgaactgaa gccagtgctc actgcagcta cagatgacgc actgctgatg
     1861 gcagtaaagg gcggagtgcc attccgttgg tcgctttcag ggtgtgcagc gtcgagtgtc
     1921 ctctttctcg accgctgaga agggctgtag ctacagacct gaccacgtcg ctcgcatctt
     1981 tgacaccaag gctgttcctt gccgcagcga acttttgact tggcacagtt gtcgcaactt
     2041 tcgcggtagt tctctaccct gcggagaagg gggtctgtgg aactcatgtg gatatgtaga
     2101 gagtggtgca tgtgattatg acagggtaac tgtgagtgat gaactctttg ggccaatccg
     2161 ggtgattatg acaattgtaa gctgtagtga tggattttct cagttcctgg cagatcgtcg
     2221 atttttattt cagacggacc tagaccattt ttatacataa aaggccctgt tcagccacag
     2281 atctggatcg aggttatggg atgcgacccc caggacgatc tgatataata attacagtaa
     2341 gctgaaaaaa ccaaacgcag ctaacagagg agaagctgcg aactgcattt gagttgggga
     2401 cagtacgtgt cacgcctgat ttgcgggatg aattcaaccg tcgcagggta cgagctgaca
     2461 gcatgcagtg attccttcag aggaccaggg tctctcgcat gcaagtctgt catgatacga
     2521 ttacaaacat tgataggtgc agtttaggaa ggtcgtttca gggctatggc ccgctcccac
     2581 aggattgccc gcagccatgg gcatgtccag aacggataat tgttgccgtt ggagtaacac
     2641 ggacccgttt tgtcttacag gcgagttgaa gtttgacctg ttaggttttt gttatgtcaa
     2701 caaatggaga tctttgcagc ctgtaattat gtttgaattt atggtcgatg tgatctaaaa
     2761 atacaaaaca atgaattcat tttttatgaa gctgttgaat ggataaataa tgagacaacg
     2821 tgaaagatgc cactgatagt acgtattatt gctattattt agtatgcgta taacaagcat
     2881 ctttgtagag ggtttgagtt ttcgctaagt agaacgaaaa cccaaaacaa acgaacgaaa
     2941 actttaaaga cgagcgaaaa ctcaagatga ttcgatcgaa atcctaacct taaccgaagc
     3001 ataagaaaaa acaaaagtcc cagccaacat gcatatgagg atctcagcta tctaaccatg
     3061 aacgaggcga ttactcgaat tggcgcttta tggagacatt ctgggacaag ataacaaagt
     3121 aaccccaggg taggcagcat aaaatatcag gctatagctg catgggaaac accgccgtag
     3181 tccgttctcg ggcactcagt agccgggccg gacggtagtt gtcgtagtat cattccttcg
     3241 gtccgatgca agccccgaat tgtttagccc gaaaggtggc atatgcaatg caagtaggga
     3301 cgggaggaaa gggggcttaa cggctgagga ccaattgact caaaagggcc agcttatctg
     3361 tctttattag gaagtgatgt ataactatta acaaccatga tcaacagctt ctctctgttt
     3421 gctcacatca ctccaatcat cagatcatcg ctccacagcc gctactcagt catatcatcc
     3481 cgcaaagcca tgtcttcttt agctgctgcg ccgtatcggc acgtcatgat gccattcagc
     3541 ccagcccagg atgcccaggt tcacggcaac tcggcactta ctaagctgac ggatgctatt
     3601 ccggacctca agatctacac acgttcatcg cctcactacg agtcccttcg cggggtctac
     3661 aataagctca ttacggctca accccttgcc atctgtcggc ccacttcggt cgctcaagtc
     3721 caggccattg ttaaaactgt ctcggggttg ggtatcccgc tcggagtccg cggcggcggc
     3781 catgatgttt ttggtcgcgg ttgcattgcc gactctgtca ccatcgacat gagagagctg
     3841 gacacccagg aactctccca agataagaag acagtcaaag tcggcggtgg tatcaccagc
     3901 aaaaacctcg ttggctttct ggggtcgcac aatctttgca cctcaaatgg cttcgcgggt
     3961 gaagctggat ggacgtcgtg ggcgtcgtgg ggggggtacg gcccgctggg ggactatgtc
     4021 ggtctaggcg tagataacat tgttggggcc aagatcgtca cggctagcgg cgatgtcgtc
     4081 gacgccaagg gggactctga gctgctgtgg gcgctacgtg gtggaggtgg taacttcgga
     4141 gtgattgccg agactgacgt gcgggtttat cccatgtcca ctatccaggc tggctttatc
     4201 gtgtaccctt ggccagaaac tgccgacgtg ttgcttcgtt tgcaggccct tctagactct
     4261 ggggtccccg acaaactttg tttacaggca gggtttacca agggcgaatg gggtcttgga
     4321 atggccataa cctacatctg gcctgaagcc gagacgattg gacctgagag tgaggagtgg
     4381 ctacagaagc tgaagggtct tggcacgtgc atcgtcgata cggttgcaga aagtaagtgt
     4441 gctgctgctc atccctgtcc ttcctactag cccgtggact agctacggca tagagaaata
     4501 gactactaac acggggaaat tatagcgacc ttcgaagctt tccaggctag catttccagc
     4561 gctatcagca accctgtcaa tgtgacatct cggcacatca gtatctccaa gttcacgagc
     4621 gacaccctca accagttgat cggcgcttgc gagtcgatgc ctgctgaggc tgattgctcc
     4681 atcacatgca cgatccttca cggaaaggcg gcccaggcaa atgtcttatc tgccttcggc
     4741 acccgacggc cgcacatcat gcttcatatc aacgccgtca ccgaggaagc ggcgcatgaa
     4801 catgtggcta tcgcatgggc cgaccgcttg gttgatggtg tggaagcgac aggcgatagt
     4861 attgggtcca catacgtcag tttcatggag tcggacaagg accccaaggg ttgttacggg
     4921 gagaattggg agcggctcaa ggctgtcaag aaggaggttg acccaaacga tgtttttaga
     4981 ttcgtgcatg gtcgcatccc ggctgcttga gccgtcagtg caccttgatg agatcggccg
     5041 tgctacagta gatagtctgt cagattagaa gtacctcatc acatcattga ggccaacata
     5101 ttacgcactt tgaatcacac ctgtcatttt attatgctcc aacatttgac tcaatcacga
     5161 tcttagtaac cttggtgttt agtccagttg tgaggtgagg ccagcttatg attcatgtac
     5221 cacattcatt atctcagaag ctggggtata ttagtgacac ctgtctatta gctctattga
     5281 cccttcagaa aagcctaata atataacatg tggtacacaa cacattttga gttacacaat
     5341 aggaaattgg aaataataaa attgagttta acatatatta gcacttttat tagggcatcc
     5401 gtgttccgat caaacccaag aaactggtac agtagattca atagtttatt ggaactaaat
     5461 tagtgccttc tgtgatagac ggattaatta aggaacagaa aaaacgtgga gatttaagtt
     5521 gattaaagaa tgtcattata ttaagggtcc accaagctat tcaattttct gagtttatac
     5581 tattatagtg cgggcactct aagcagcctc aattatctgt cttcttatct ctctattact
     5641 tccagaccta cctttttatt gcattgcatc atgccacccc agaaatgaac catgtttgtc
     5701 taaaaaaaaa ctaatgtaca aattcctgac ccttgacatt cttccactcg atgcctaatg
     5761 aaggaagaac ggcaaaacaa gcagccgcaa gaccgacgta gaaataactg cggagcgctg
     5821 cgttgtactc aacaagcacc tcagcaagac gatcagctgg aataacgtgg cgtaattggg
     5881 tagcaccagt gccaatgatt ctcgcaacat caatcccgtc aaatgatgtg agacgagatc
     5941 tcagctcatt gttgaagacg gcttgggcaa cacagacgag aactgaaccg ccgagggact
     6001 gggcaaagaa cattagtgac acacccgtag gcacatcact ttgcttgacg gcaacttggg
     6061 ttcccaagct ggccagctgc atgccctgac cgataccgag accgaggatg atctgatatc
     6121 caatccatgt gcgggttggt gtgtcgacaa caaaagtggt gataagaccg ccaccgactg
     6181 acatgaaaat tacagaagag aaaaagacgg ggttgaacca gccgacgccg ttgatgacac
     6241 caccagagac gatggcacca aagacaagcg acaggacaag agggagtgtg tcgataccag
     6301 aggtgatggc atctgttcct cgaatacctt ggaaccagat gggcagtgca atcaagaaaa
     6361 caatgagaac agatccaaga cagaaggcaa agattgtgcc gagccagaca tttcggatct
     6421 tgaacagacg aggtgggaca gtggcgttct cttgttgcca gatttggatg ccaataaaga
     6481 caaggagaag cacgcaggca agcacaagaa gtgcaacgat gcggccgctg tcccaggcgt
     6541 atttctcacc accccattga agagcaagga tgaggcagat gactccaggc aggaagacga
     6601 ggtttcccca tggatcgagc tgcttgatct gttgcttgac agagacaggt tcattgacgg
     6661 gaaacttggg gaagagaaga ataaggcaag cgacagctgc tcctccgacg ggaagactgg
     6721 acacgagata gttagcattg ttcaaattag cctaaaggtg gaggtggatc gatacttact
     6781 tgatgtaaaa gcaccatcgc caagtgacgt gatcagtaaa agctcctccg atcaagggcg
     6841 cgatgaccga agcaatgccg aagacggccc ccatcatgcc cacataccca gcacgtttgg
     6901 acagaggcgt gacggtggtg atgaggatgg tagagccaga gtagatgccc gcagagcctg
     6961 cgccagcaat ggcacgtccg atgatgaagg cgaccgagtt gggtgccacg ccgcagagga
     7021 gggaaccaag ttcaaagaag aaaatggcaa cgaggtagac ggtcttggtt gggtaaaagg
     7081 taaaaatgcg cccccaaaga agctgagtag cagagctggt gatgagataa gcgctggcgt
     7141 accaactgat atcaccgagg gcgttgaagt catctgtgat gcgagggatg gcagtggcga
     7201 tgattgtgcg gtccaaggcg acgaggaaca tggctaccat gttggagagg atgatggcag
     7261 ccagtttgag gccgtggggg tacttggact catcctcagc ttcctcaggc ttggattcag
     7321 agggttctga tgttgggggg gcttcattag gtatgggagt tggagtggtt gctctgtcga
     7381 gcttctccat gtcggtgttg tctgtcatgg tgttgctgcg aaagagaggg tattaggtga
     7441 tgatgaataa ggattgaatg gtgatgcaga tggatgacaa gattgaggaa aagacagtcg
     7501 aagataagcc ttaaaataca aacatttaga agagccattc cgggagatga taccgtccgg
     7561 acgggggaaa gaaattaaca acggagtaaa agagttcatc tcggcgacgg agtaggatta
     7621 attgttgatg gcatcttgag agcggtcccg ctgtgtcgtt gtccgtgtcg ggtcgggtat
     7681 aaagacgcta aaactgacct tcgggaccga aggccaccat cagccctgga agtccctgag
     7741 agcggtcccg cgcgggcatg gacagtaact gttggtggcg tccacccctg atttccttgt
     7801 tcctctcatg atctgagtca attgttattt gtcttgaccc tcatcttatc cgaggtacac
     7861 aaacaaaaga acctgtccgc ttactgatgc gtggcttatg cgcgtaccta ctctcgtcaa
     7921 taccaaccct tgaattcttt tccaactacg aattatccca acaacaatga cagaggcaaa
     7981 gctcaccagg ggacactcgt gcgttccgtg ccagcatcga aagattagat gcaatggcca
     8041 gactccttgt gcgtattgta tcagaacggg caaagaatgt gtgcgcatgc gtgtatcgcc
     8101 ttctcactca cgcaatgctc gcttaaatca tcgccgcctt acagctgccc agacggggag
     8161 tcccagtggt gatggacagg tcattgtcag tggagatcag cgtcgctatg tcgaagagta
     8221 tgtccttgca taataccaat tttcgttaga catttaataa caattttata gcaataaatt
     8281 atggaagtcc ttaggcgatg aggtaagtat taattaatta attttacctt gcaatgtggc
     8341 ttattttgcc atggcagatg caaggcaaag atgtcagccc agatccagag cgtccacctc
     8401 tgcgaacacg gaccgacacg ccctcaactg aagtaaacct catattcagc catcaaaggc
     8461 caacttctat ttcggtaaaa tatccatcag ctgtgcattc atttcagcta tggcaagtct
     8521 ttatcagcaa tgtccatcct ctgaccaaga ttctacacgg cccgacagtt cagaaagaca
     8581 tccttgaaac cttttctgag ccgacatcaa cccccggccc tacagaggcc ctcatatttg
     8641 ctatctatct tgtcgctgtc gtctctttga cagatgccga gtgtcgtagc aggtttggcg
     8701 agcctagaaa ggatttgctg gcgcgatatt gcaacgcaac tgaagtagct ttgagcaaag
     8761 ccgatttctt gagatctaca gatctgaggg tacttcaggc ctttactctc catctggtaa
     8821 gtatcaaact tagccgtaat attatttaaa gggcatacta atattcatca gctttcactc
     8881 cgtcacatct gtgaccatga cattctatgg ctcctaacag gtcttgcgac acgtatgggc
     8941 caaagaatgg gactccatcg cgaaagctca ctcaaagatc tacccccatt tgaagctgaa
     9001 ctacgacgcc gagtctggtg gcagatcgta atccttgatg gccgagcttc acaactgacc
     9061 ggtgcatcca tgaacccaaa catgcaactc tatggagata cccaacaacc catcaatctc
     9121 agtgacgctg accttgtgcc atcagcaagc acaataccgc agccgtcacc catcaccacg
     9181 gacatgctgt tttgcaaagt ccgcattgaa atcggtgtgt ggatgattga acaaaagtgt
     9241 ctactcggtt ctgaatctga atcgtcgact acgggcaaag caaaattttt caaagctatt
     9301 gatgagcttg aacgtcatat tgaggaaaaa tatcttgcca acatggacaa ggaacttcca
     9361 ctcaaccttt tgacggcata tcttgctcga tctgccgttt gtcagctacg gctctcggtt
     9421 taccatccca ttcatcgccc ggagagggcc tcggatttga gtgctgaaca aatcgatatg
     9481 ctacttgaga acagtctgga agtgatacgt tatgacattc tatcgcattc gactccagct
     9541 ctacaatgtt acttgtggca cattgccaat ttcttcccat ttgagacctt cgtgcttctt
     9601 atcagcactt tgtctggtcg accggcaggt caggtcgttg acacggcatg ggaggtgatc
     9661 gaccaagtgt atgagcacca cccatctttc gtttcagata ctagcgaccc tttatactgg
     9721 gctctgggaa acatcaccct caaagcctgg gatcagaggg tcacaagtgc caggacacga
     9781 ggaattactg ttcctcgcga gctaccttgc atagccaacc ttgtccatgc acgagctaca
     9841 atggccaggg catcgtcaca acagccttcg accacagacg tctctggacc agccacacct
     9901 caaagtttac tcctggcaca ggaagcgcca gtcgactatc ttggtggtct aggaacgaca
     9961 aatgagcttg cctcacagac ggacttgggc atggcgactg gggaggaact tctgggtatg
    10021 atgaagggcg ttgatgtaga ctgggacttt tggcagcaat tattggacgg gaatggacat
    10081 gatgcacggg cgagagatga tcaggaaacg ttttactttt cgtctttcat aaacaaagcc
    10141 taaacacgaa gcgcaataca aagtactttt cttcaaactt atttctgtag tgatttataa
    10201 agaatgaagg caatctgctg cttctatctg aaagatgaga aagacaaaga aatacaaaca
    10261 tcaaagaaga ataaacataa atacacaaac agccctctcc atcgtgtcta attgtccaag
    10321 gcccgagcca ggaatgcaga gacatattcc gcattccgtc ctctcttcaa catactaaaa
    10381 tgattcgctt ccgcaatccg atccatgaac aaaccctctt taccaccaag tagcgcctcc
    10441 caaccattcg gaccaaagtt tgttctgttc tccaacagcc atctcatctc gcgtgggtca
    10501 tcgtcacggt actcgggacg agcactatca gagtctttgc aaactccgtc ttctgcccac
    10561 agcatgtatg tctgcggcgg tgcagggagc ggtgatgcta gaccgactag accagagtcc
    10621 caaggcactg cgacataagc atccagagcg tcaatgaagg ccaggaaatg tgcaagaagc
    10681 cattctggag ctttgacgct tgttccagca gtgctgtgcg ggttgtctga tccaaagaca
    10741 ttctgcgaat tgaggaaatc gtacaagcga ggaggtagct tctcaagacc aacgggattg
    10801 ggagagtcaa tcaagataag gcgatcgact tggtgtcctg ctctggtgag gatcagggca
    10861 gcttcataag cgcaaatgcc accggctgac catcctccca aattgtaagg accctgtggc
    10921 ttgcgacgga gtatctcgtt gacatagagc tctgtcaagc ccttgagtcc aaactcgacg
    10981 aggtaactag cgtccttcag ccatgggcag ttcaacccgt agacagcaac atctccgtct
    11041 ggagagatcg ggggaaggga agcgtaggat gtggcagatc ccgagccatc tggtagcaag
    11101 aacaaagtcg agcgagcttt actgggactg ccctgtagaa gcgtcgaact ggcttggaac
    11161 tggtgaagcg agtgactgct gactatcttg tcctggtcct cttcgctcat aggtggtgta
    11221 gtagcgccag actcgatacc cggtgctgga ctgctcctac cactgccatc actgccgctg
    11281 ctgctcttat tgtcctgatc gacaagtcct aggaataatt taaagctgcc caaagtggga
    11341 cagttcatga atgctgtaga ttcaacgtcg agacccaatt cctcacgcat gcgaccagtg
    11401 atggtcaatg agaggagtga gtcgacaccg tggtccgcaa agtcgagttc atcgtccgaa
    11461 agaacgtcaa gaccgagacc gatctcttct gacaagatgc gaagaagagg tctcaatcgg
    11521 gagtccatgg atgtatcggc tgcgaacggc agagcgatag cttgctgcgt gggtgctgaa
    11581 gtgggtgggc cttcaccgga cctgacggga ggcacatcca ttcttgatgg aggcacgtcc
    11641 cgtcgaccca tgggagcatc aactggaacc gcgttggcag atggcaagac tgtgttgagg
    11701 actcgtcgcg gcaaaccttg gaactgttct ttacgttagc attgttgttg acaaagattc
    11761 gtgttactca ctgttatgtc tccataaaca ccaaccacag tgtcatcctc atcaagaatg
    11821 tacaagtcac cagcgaactt ggtgctatca atgggcctca tccggatata agtccgatag
    11881 gtaccatctt cacggaacgc cttggccaat ctcatcgact tccagccatg attgacgtag
    11941 acgtagtcat tgggcgtagt ctgatgacag ttcatcatga agccggtcgt ctgaccacag
    12001 ctgtcaatcc acatgggatt gcagacgaaa cctcccgagg gagtttggaa gcgcactttt
    12061 gctgtgccct cgagctcttg gctgtgcaag acaacctcct gcagaccctt gtagccatcg
    12121 gcatagtcga cgagggagga gaagaccttg tagaccattc cggttgccaa catgctgtcc
    12181 aaaccttgtg ctgatcgctg cagaaggtag ttgacgctgc gattgatgag gtaggcttgg
    12241 cgatcccact ccgcttccca ttgcgacgga tgctcgagtc gaagttcgca gttagcatgc
    12301 ttgatgtgct gaccgttggg accagtggtg gagatgctca tcagcgccgt ggtgctctgg
    12361 attgggtatc gcacttcgat gcggaacggt gtagcctggg gcgttccgtt catgtcttct
    12421 ttgagaagaa gtggcttgtg gacctcaata ccgtgaacat cgaccgcata accctctaag
    12481 tcggtgcggt agttgtccaa aatgtactta cccagcgtca agccaacatc agcgtacacg
    12541 gaagatgtgc agactttgac accgttgacc cgatgacctt gggcaacctc tgacaataga
    12601 gggctcgcga gatctgtctc agcaacgata gtcaacacct gatcaaggga agtctcctgt
    12661 agaatcttct ggaccgaggg tgttgataaa gctgagactg cttcaaccga gctgttagga
    12721 gcaattggag gatcaccttt agtcaaggac caatcgtact tgtactgtat ccagtaattc
    12781 ttgtgctccc agctgtaaca aggcagacga agtacctggt gagaggcctt gaagtcgcga
    12841 tgatactcgt tccagtcaat tgtcaacccg ctgctgtaga gactgctcaa accatcagcc
    12901 aacaccttcc agcaatcgtc atttcggcga agcgatgcga tagtaggtgt gcttggacca
    12961 aggctggact tgaggaaggt agagcagaca acatggggac caatctcgat ccatagagtt
    13021 gatgtcttgt tgatgatctt ctcgcgctcc gcagcatgta gagcaccctc aaagttgact
    13081 gtctcacgac aatgtcgctg tagatgaagg ggaccaatga caccatggtt tccagggctg
    13141 atgacagagc tgtcaagggc acaaagaaca ggaatctggg gggagtggaa ggtgacgcgc
    13201 gacgccgctg tatccaagtc ggagagaatg gggtcaacct gcgctgagtg gaaggcaaat
    13261 ggcaccttga cgcgggtcgc cttgatgttg tcagccgaca aaaggccaac cagctggtca
    13321 atgtcggcaa cgcgtccact gatgacgact tctcgtggac cattgacaca tgcaacctcg
    13381 tgaatgttgg catcgaggaa ctgttggatc tggagtaagg atgcccttac tgccagcatt
    13441 gagtgggttc ctgcctggca cttatccacg agcagctgcg ctctgatgcc agtgaggtaa
    13501 atggtatcat tggcggacag aacaccagcg acgtgtaaag cagcatagtg gcctaagctg
    13561 tgtccgagaa caaagcctgg ctcaacaccg aatgacttcc atagcttggc cagtgccatc
    13621 tgcaggcaag tgagacccag ctggatctca acaggactca acgagtcagc ttccacctct
    13681 cctcggatca gtgggaggat tgacgggaag ccttgggctt gggcgatact gtcgtaagac
    13741 atgatctcag agcggaaggc tgtgaaagat gtaaagtact ccttgcccat accacggtat
    13801 tgggcgcctt ggccgctaaa cacaaagccg acagagggcg cggcagcggg gatcctcttc
    13861 acatcctggc gttcaatggc ggaatcaagg cccttcagca gctgttcacg agtctgtgct
    13921 gtgaccgaag ctcggaattg atgatgcatg cgcctggcgg tggttgtgta ggacagcttg
    13981 ctcaggaagt cgacctccga gtcaccttgg ccttctacaa gctccttgag attggcgagg
    14041 ttcttcctga gggaatctgc tgatcgagcg gacatagtga caacatggga tgagcgaggg
    14101 tctgtaacat ccgaaactac cgatggccga ggagcatctt gcagtaggac agcagagtta
    14161 ccaccagcgg cagagaagtt attgacgaaa gcaatgcgtg gattggcttg accagatctt
    14221 gtccaagatg tcggaacttt ggcgatatgg acattgcgct gagtgagatc cgtaggaaaa
    14281 tggtgattga tctttgtctt gataccacaa tgcggcggga tcatgttctt ctccatcata
    14341 agcagcgtct tgatcagagc aatgatacca gatgcggatt caccgtgccc gacattggcc
    14401 ttgactgaac ccaagtgaag gttttggtga ggcaatcgac cgccaaagcc gctggtagga
    14461 gcaaacgtct tgaggacgga tgtcatctcg gttgcgtcgc cggcttgagt gcctgtgccg
    14521 tgcatctcga tgtagctaac gttgtaggga tcggtgcccg actcacggag gagtttggag
    14581 aagatgtact cttgagctcc ggcatgtggt cgagtgatgg atactgcttc ggctgagtgg
    14641 tttgtgtaag cgcccagaat gacaccgaga atagggtcat tgtcagcttc ggcgtcctcg
    14701 agccgcttga ggatgatggt tccgacgcca tcagctcgac agtatccgtc tgctccatcg
    14761 tcaaaggtgt tgcagttgcc tggagcaagg tcagtaaaaa cactaaaaag aaggaagctt
    14821 ccaagatctg tgagagactt accggttctt gataggaagt ggcctcggtc caaaccagcg
    14881 aagttgtcag ggttagtcat gacattggtt ccgcccgcaa tagctgtatc gcaatcattt
    14941 ctccagaggg aattgcaagc caagtgtagg gcagcgagac tggaggagca agccgtatca
    15001 acactagcgc taggcccact gaacttgaag aagtagttga gtcgaccagg agtgaacgct
    15061 ctgttgccac ctgtagtctg caatcagtat tgtcgtgaaa cgcgaacaaa caacttacca
    15121 ggaataaaat aagtgtcgac attctgccca ctgttgacct ctctccaatc atcgctagtc
    15181 atgccgtaga acacaccaac acgatctctc tgtgtcgaag gtgttctgtc tggtacgata
    15241 ccagccatct caagcgcctc gtaagctgtt tcgagggcca ttcgctggcc aggatccgac
    15301 tgctcagctt cctttggaga catgttgaag aacctagcgt cgaacagtcc tggttccttg
    15361 atgaagcagc cattcatgac cttgctggtg ttcttacgtc gcccagtagc gtcgtaatgg
    15421 agctctgcgt tgaatcggtc ctcgggaatt tgtcgatgaa catcgcgacc tttgtagaga
    15481 agatcccaga attcacccaa gtcagctgcg tctggaaagc gaccagacat agcaacaatc
    15541 gcaattttgg agttcttgct tgatgactcg gtttgtgtct ctgctgatga gtggctggtc
    15601 gaggctttgg gccccatgct gttgtccacg gcgcatcgtt ctgctagcgt cggctccaaa
    15661 gcagacacta gactgttgga gacgctggtt gctataggct ttattatggc acgtgtagat
    15721 gagctaacct cgagaagctg ggccactgct tgtgagacct tggtaagatc cagtggctgt
    15781 atgagcatat cactaacaca gcagcggagt agatctgcat acttgagtgg ctgtaactcg
    15841 tcacccgagg agcttgaaat gagtggaatg atggactctg atgcaaaaga aggtgcagac
    15901 aggctaagga cctcgtctac atcatccatg ctgtaaagat ggctggcgtg gtacggagca
    15961 tagatcggca ctggaagaga atctttcggt gatgttgata tactgtgaat gaacttttcg
    16021 aggacggatg gtggaccact gatggtcatg ttgtgatgtg cgaccgagct gatgtaagga
    16081 actgacgatc gagcaagtcc ctaaagaaga gtgaatatgt tttatgagag ctccaaggac
    16141 aaagaattgc ttaccatttc aatgatgaat gagtcaagtc ggtcttgcgc agattctctt
    16201 ggtagtactg cctcgggcac aattatggac caagtggcgg agggcctgtc tggtacatcg
    16261 aaaagggagg tagttcgcca tacccgtagt ccgacgtgca atgccacacg aacagcatct
    16321 acaccagctg ataccagttc actcagtgat gtggagcaac tgacagcagc agcagcgagt
    16381 gaaccaacgc aaagtccaat aatgcgactg ttctccgaag gaaaggtacg accttgtcca
    16441 tcgtaaaagc tggatggtca ggagagatct atgggtactt ggttatgtta ctcactgaat
    16501 gaaactgcaa agatggtaaa agcatgctaa agcgcttgtc aaagcagggt taccactgcc
    16561 ccaatctgac ttggagacga gttcctgaat gtcggcaaag tttggaaaaa gcttctgttg
    16621 aactgccggc aaggatgata tctcccttct aagaagtgcg tgaacttgtt taacaaaatg
    16681 tgtcaagtaa ggactgttgc ctttgaggag taggtctttc agtggagggg caaagcgtgt
    16741 gctttggtcc ccaaaaacga atacctccat cattgatggg gtcatgttga atgaactaaa
    16801 agagtaagtt gaaatgtggt ttgaactcca agtagttgtt actggagagg taatgaagca
    16861 caatccccta tatataggag ttggtatgtt gatgacagat gataatacag ataagcatgg
    16921 cacttgacgt gattcagagt tgggattagc tgcttgagca acacaatcat aattcagaga
    16981 taccccacga ttgtcttggt aagtgttaga cggcattcgg atcacgtcgg tccgggctcg
    17041 tcggacatgg atagtcgggc ttgttcgtcg ttcggtgcag ccgtagagat aactccgaaa
    17101 caagcacgct gcagactgtc agtgccgagc agcagtctct cgtcattcgg gccattgatg
    17161 cactggatct gacagcttct aatcgacggc gtatccatac tcttatgacc ccttgcgtat
    17221 ccagagctcc agtttatgca actctgtcaa ccaaatccta cccagcactt cgataacaaa
    17281 ctccaacctg catcatgtcg cctcatagtg atacccaaga aacctctcat gaggcaactg
    17341 tcaccggtca acctgatacc cttgtttgcc taaccatcac ggcctacaaa aaaccttctc
    17401 ttagcgagaa agagtacagg caccatatga caaaggtcca tgccaagctc gtcagccctt
    17461 tgatggagga gtatggtatt gttcgctaca ccatgacaca caacacgaaa gagacacgcc
    17521 cgatgcttta tcagctctac gatccacaat tctccaacca gtcagactat gattgcatcg
    17581 tgcagtttat tttcaaggat atcaaggact ttcttcgcat gaaggcagat ccgcgtttcc
    17641 tcgaaaaggt tgcgcctgat cacgtcaact ttgctgacac caagcgatca acgtaggtta
    17701 tcctccacta cagaggttat catgaacgat tttactaatg aaattaggat gactgttggg
    17761 tattatgagg aatttgtcaa cgatggcaag gtcgttccca aggactgaag catgcttgta
    17821 gaatcaatcc atagatttag ctatggttga cagcaaacga attgatgatg attcatgaat
    17881 tccaaacctg aagtgatatc ggtaccgata agttgaacgt gattggactg accataaaaa
    17941 gactcagcag gcactgccca aattggttgc gcgtcgaagc ataagatagt tgtgtaacac
    18001 cacctgttag tacgtcagtc gcgatatcag cgagatcaaa aatacaaaga atagataaga
    18061 attcatatac gccatggtgt tggtaatttg actaaagata aagatggcct cccccaaata
    18121 gataatacta gtcatcctgt aagctgatgg tcaataagca catgttgctc ccctccggct
    18181 gcctcaaatt cttcaaggtc agcctcgaat ccgtttcgcg caagatcgcc tcccagtcat
    18241 cgacaccgcg ctccttggcg ttgaacacct ggcgcatagt caagtctcgc gttctgatga
    18301 cacgctcccg taccgacggg atacttccgg gtgacggcag aaccgtatcc atgatgagga
    18361 gggttgcttt ggctgactcg agcgctggga cgagattacc caggatggtc tttgcttcgg
    18421 cgtccggcca gtcgtggatt atcattcgca gcatgtaaac ggttgcgtct ttggttggct
    18481 gtgcctcaaa gaagttgtgc gctttgaagg tcaccctgtt atcggtgcca atcacatgct
    18541 tgcttactgc ttcttcatgc tccttggctg ctttttctcc gttgaccacg gtgtcaaggt
    18601 cttgtacctc aaagcggagg tgtggataag cagcggctag agcatagctt gcatggcccg
    18661 cagagcctcc aatctgtaac gagttagtaa gttgtttttg aggagagatg aggcgcttga
    18721 tatcacttac gtcaacaatg agggacttgt ctggcaggct ggcccagtca aacccgttga
    18781 cgagatggga gagatccatg ccttgaccgt cagtcacact tctcatgtat ccagagaact
    18841 gctttgtcat gacaggactc tgggacaaat gatcaaagaa gggcaaatca tgattgaatg
    18901 cgatgttgta agctgtctcg gtcttcttta cacttcctgg ccacttttct gtagcttgga
    18961 ccatggcagc agcggtcgga attgaggcag tgaacatgta cgaggcccag tcgcgcatgt
    19021 tgggaaattt gacaaacatg gcagaattgg cagagtgcgc gacttgaccc gtggttggtt
    19081 ctgccaagat gttgcttgtc attgccatac gcgcaacact tttgagtaga gactcaggta
    19141 cattggcttt ggtggctagc ttttcatatg acagggaacc atcaagcgga atgtgagaga
    19201 aaacatcgaa atgatgtaac cattgaagtg caaagatggt gtgatactgt cacggctgtt
    19261 ttagctaaaa gtcaacgaga atggaggcgt ggctacatac actggctgtc atgttgggta
    19321 gaagctcgct gggtccagat acaagattga acagtttcag ggctgcctca gcggttgcca
    19381 cacgggcttc gtgggctgct ttgggggcat ccttgggaac aacgtatgtt ggaccatcag
    19441 cttcaaatga tggctgtgga aaaccttgag attgcaattg cgtgtccaag ttcttagctg
    19501 ctgaggacac agcgttcgca aggtcaatga tgagagatgg agaagaaatt gaacccattg
    19561 tggctaggct ggctagtgat tgactgattg tcaagctgtg tctttgtaca ggcgctgaga
    19621 tagggacttg gagagtaaca aaaatgccgg ttacagggat cttacagtgg atgccgtgtt
    19681 ctctaacaag actttatgca gcgcccaaat gctcactacc aatctagact ctacgcaggt
    19741 acctcacaat gttccatgta ctcgcaccga gtacggggtt cggactaggc tccgtaacca
    19801 taatccccga gcccgaacac tgacccaccc cgacccgaag agcgacggtc agcaattatc
    19861 tggtgtaaca cgattgaagc tgtaggaatt agtctgtgta ggtacttacg gaaatcatgc
    19921 catgcgaaat aatggacaga aaaagacata ttaataattc attgatgact gcagatcaac
    19981 cagctttctc gtatttgagt tcctcaagat taccaatctc actgaacaat taattagcct
    20041 gtcgttttgt ttcactgaca atgcctaacc ctacagtcgc tattgtaggc cttggtgccc
    20101 tgggccttgt aactctcaag aaccttcgag aagaaggctt tgatgccgtc gggcttgatc
    20161 gaaatgacta tgttggaggt ctctggcatt ttgaggaggg aaacaaactc actgtaatga
    20221 gaagtaaatt taccattcgt ccctatttaa aattcattct aatcatgtga gaataggcac
    20281 gctgtccaac ggttctaagc agcgaggatg tttcacagac tttcccttcc ctgaaggtat
    20341 accatcattg atgagtactt actgatcaca catgtactga ccccactcag acagtcctga
    20401 cttcatccct gcggagggta ttgacagata cctgaaagac tatgccaaac actttggact
    20461 cttggaacat tgtcgccttc gcactagctt ccatggcgca agatacgacg aaaagaagca
    20521 gcaatggcgc ttgtctctat ccacgcctga cgctccagag ccacatttcg agtggtttga
    20581 caaggtcgtc ttcgcaatgg gagcagatca gattccttcc aggcctaaga tcgagggcat
    20641 tgagaagttt aaaggtcatg tggagcactc catgtcgttc aagaagtaag tcaagtccct
    20701 gacggtaatg tggttttgtc taatactaca atagcccaga gacgcttgct gggaagagag
    20761 taatggttct gggcttcggt aacactgctg ctgacatggc aactgagttg gctcctattg
    20821 ctgaccaggt ttacctcgca catcgacacg gtgctattat tgtgagtact gatatccttc
    20881 catcggggaa tgagagacta actgtatcat aaaggtccct agatgggtca aaggcaaacc
    20941 agtggaccac gtacgaacct accgcaagta tgtgatcctc aacttgatga accgctacac
    21001 tcctggtctc tgggagaaaa caatgaacag cgtcatcgga aagcttgtcc acaatacctt
    21061 tgacctcaag ccggagtggc gctttgatcc tgccccatca atcacaaacc agcgtcctct
    21121 tgtcaacgac gagttgatcc catctttgga gaagggttct atcattagca cacacggact
    21181 ggctcgtgtc atcgatgaaa acacagtcga gacaagcgat ggccagcggt atgaagtcga
    21241 cgctattctg ttctgtacag gattcaccgt ggactattca gtcgtcggca tggacgcaga
    21301 tccgtgtcga gccacgacca cagattggca aaagtctaga ggcttcacag gtcgccctct
    21361 gccaagactg taccaaaaca tcttcagtct tgaccatccc gagactctcg ctttcatcgg
    21421 tcatttatct ttcatgaatc ccgcattctt catgtttgat cttgctagca tggcagtcgc
    21481 ccagctatgg aaggatccat caggtttccc atccaaagca gagatgaaca aacaagtcga
    21541 tgaccaacac gcttgggtca ttgatctcgc caagaagggc cccgttacac cttccatcgt
    21601 caaagcatca gagtggatgg aatgggtcga ccgagtgatt ggctctggct tgccagaaca
    21661 tcttgggtac actatgaagg gatggaactt ttggatgcgc gaccgcaagt tttgcaacat
    21721 tatgatggat ggcctgctga gtcctcatgc ctaccgtgtg ttccctggta agcgaaaggc
    21781 ttggccagga gcgagagatg ccatcattgc tatgaacgct gatcgagaag cgaggtttgg
    21841 acctatggat taagatgttt gttactttga tatttggatt gaacgctgag ggtcactggt
    21901 cataggaaca ggaaatcatg tagttaagga acaatagata tgtttgtagg tagagattaa
    21961 tgatagaaac attgggcaaa caaattcttc gtggttcctg attgactgtt gtgagattga
    22021 tttgtatatt aatgcagatt gaaagagtga attgcaatgt tgttgattgt atctactttc
    22081 aagctattgt gttacaccac gtgtgagtct ttaccaagaa tcatttcaac gcagtcgatt
    22141 gtagagaaaa aatggtaacc ctaacaaatg gaagcacgat aacaaataag acaaactgtt
    22201 ttagatcatt gtactatatc tagtaaacta cgaagaacga ctgcttgctt catccgaaag
    22261 ccagccctgt aacacttgaa tcaaaccacg gatcaaagtc tcccaccgtg aatcactagc
    22321 tgaagtttca cctgaatcct tcttcgggcc accactagga gataccgcca gcaatggaca
    22381 ttgtttatcc actgtaccct gtttccctcc actctccaac tccggaagtg ttccgggcat
    22441 gaagccccgc tgatcaggtc cgtactcagc aggaatctgc ggccaaacat cgataccgtc
    22501 aagaatcgcg atagccatgc caccagctag atgtgtttct atgtgacagt ggaaaagcca
    22561 gggtccagga tttgtgacct gataccgcag cacgatccac gccgaaccat cgaaagaggt
    22621 aacgaaagtg tctctccact tgggcgtgtc aagatcgaag ttgtgtggct cagcagctat
    22681 ggcttcttcg acagaggaat agttccaaat tcccatgcca gagccaatct gccatgtctt
    22741 tcccgtgtgc ttatgcatca tgtgcgggaa ctcttgcggc tgccctggta aagagccaac
    22801 ctggagcacc agatcaaccc agctcccgtt ctttgtgcga ataacaagac cttcatccat
    22861 cgcgtctgct gagtgaggat catacagaag cggtccatat gcgctacggt cctcttcata
    22921 catgccatgt ccagacatgg tatactgcca agcactcttc catctatgcg ttgagaggac
    22981 atgcatcgca tctgccttgc gtgctggtgg attgggagga taagggggaa ggtgttcacg
    23041 atcgagtgta atgacagacc catctttggt gctgttctga ccaccgtagt caatcacacc
    23101 cacactatca ctcccttgaa tgccgccttt gtatcggagt gtagcgaatg ctgagatgac
    23161 ttgggtgaga ccactgtctg cgacacggat tgtatagtcc ttgggtgttt tatcaagctt
    23221 gatcataacg gcatagcgct cgcctgcata catgtgcacc gtgttgacgc gttggggaac
    23281 aatataatgg ccatcaactt cataaaccca catgtcatgt tcgtcaacag aaaagacgat
    23341 agtcttgaat gtggcgccac cgatgaaatt gagactagcc cattgatccg ctgggtcaac
    23401 ttctatcgtc tcgttggtac cctcagcagg ggtgcagccg tgttgtaggt gtagagggat
    23461 agtctctggt tttccagtgg ttaaatatgg gccttgggtt gatctcataa acggaaagca
    23521 ccttggattg ttagcagcct atccagtgag taaatctgac gttacatacc ctttatcgtt
    23581 gacttgtcga ggatacaagc cgtacttcat gtatgtgctg gtgtggttga tcaacacgtc
    23641 aacgtcggga caatacaagc ttccttttcc gttgacgaga atactgtctg agcagctaca
    23701 tatgttttga ttagcaatgc agtgcactat tctgcatatt gtaggaactc acaagatggc
    23761 cattccggag ctctcctcgg cagccatgta ctcccaagac atgaaacggg tccaatcaga
    23821 caccataacc agtttggggt cgataactgc acgactcatt gcgtcgatgt cggcttgttc
    23881 tttgctaatc agatgccatg gtgctggggc atctggcttt cgcctacagt acttcttagc
    23941 attaatcgca aaattatcaa ctcgttgaac gtacctgatg aaaattggtc cgtaaagccc
    24001 atcgagaacg gtagcccgtg agtgagaatg gtaccaatgc gttcccgctg gtgaggcttt
    24061 gaaccggtag atgaagcttt ggcccatttc tattggcttt tgggacatgc ccggggttcc
    24121 atctgaccaa ggtgtgccca tcatcctgac acagttaact cgtctatact cgatattgac
    24181 atgactcttt caacttactc aaggccatgc cagtgaacag tagtgttgaa tggcatttta
    24241 ttgtgaactg tgacctcaat gtcatcatct tcgtcgcaga gaatcgtcgg cccaggaaat
    24301 tggttattga ttttgatcat atttctctcc tggccattgg gtgctcctgg ttcccacgta
    24361 atggtccagt ccttctttac aagggcactg gccacgagtg ctgaaaacac ccatgctagt
    24421 aaaagcaata ttagacgtgg agaagtgagc atcctttggc gctgtcagct tattgcagta
    24481 cgaaaattga gcaacctttc cccagctgcg aatattactt ggagggctcc tttttcttaa
    24541 tgaattgact ggtcctccga atattcgtat attttccaag ttgcattgcg ctgcagtcat
    24601 ctttgaaagg tgcggttaca ataccgaatt gatgaagctt gtctcggggc gtgtctcggg
    24661 ccccgatgcc ccaccccgtg ctccggcccg aaggctcggg ttgactggtt cggcagacag
    24721 ttgatagcaa ttgacatgtt ttatatgctg tcatcaatgt cagccaagtc caattataca
    24781 ctcaatgtga agataattgg cgaaaatgtc taagcagaaa ccttccctct ggagggcgct
    24841 cagagcgctc tcgttcatca tatcaatccc tctgcttatt caataccttg tcctgaaatg
    24901 gtacagcacc tcacaaaata caccaacccc agtcttccat gaaccaaatc acgagacaaa
    24961 tctcaccgtg tgggaggtct tgagtaacga tgaccgcgtt tctaaatttg tcgacgttat
    25021 aggcaaattg cctgacattg tccggggtct ctcagcacca caggctcgct tcactgttta
    25081 tgcccctgta aatgaggcgt tcgactcttt ttatttccca cctgatccgc ccccattctt
    25141 tggcctgttc atcgctggat gtcatatggg accagggcca gttccagctg agcgtctccc
    25201 gtcaatgggc acggtttcgt cttttgtcaa tggagacata ttcttcacct acaagcaacg
    25261 tatcagtgta cagaaggaca aaagcggact tacactcaac cgcgcggctc gagtactccc
    25321 agtcaatgca tcgcaatcaa tcgccgtcaa tggttttgtc catcatattg acaccgtctt
    25381 ggaactcccc aactcgactg cccatgccct tcgtaccaga cctgaactat caaagttgcg
    25441 acggggctta gaggcgacaa aactatcaga gagcatctac gacaccaatg ctcatgtgtc
    25501 gcaaactatc tttgctccaa ccaatgctgc ctttgatcgc cttgggaaaa ccgcaaccaa
    25561 gttcctgttc agccatggag gtagacctta tcttcgtgca ctgctaaaat atcatgtcgt
    25621 ggccaacaaa actttgttca gtgatagtta ctggcctcat ggcggagcta agttgatgga
    25681 cttgagtcta attccgaata aggactctca tcaggtgagc gctgagaaac aaactacaaa
    25741 attgaattga aactgaccag atatcttcta gtttgatctg ccgaccttgc acaacaatct
    25801 aactctacag gttgaaagtc gcaaaattca taagaagtgg catctgaatg tcttgaaaga
    25861 tcaggtagct gaaggcaaga gccacgattc tattccagtc tcaatgcccg atgttattct
    25921 gatggatgga gttatgcatt tcatcgattc tattctattg ccaccggcca agtcggagca
    25981 aaggaagact tcttggctga gtcgacttaa atcgtcgctg ggacataaca agcaaagcat
    26041 tgaggacttg gtaactttac ttgggcccta cattgatgag ccttgagtgg ctaccggggt
    26101 tatcgatatc catcatgtaa cagaaaatct ttaactttaa caaatgtaga ccaggcctgt
    26161 ggtccgagcg acggataata ttagtagagt gcaaatatcc atactcagtg cgactcgaat
    26221 gaggcttttc ataagcaagt tcatgaatca attaaatctt taaagtttta aattgaaaga
    26281 gacacgacta gcgtgtccca tcatactctt gtatgtaact ggtacatctc ttctaacatc
    26341 ttaattattc ttatcactgt agtactcgtt cacccaaggt tgatcatcct cagttccgta
    26401 agcacttcca ccataggtga gatacccttg agtatatggc ggagcaggga acttgccacg
    26461 gatctgctcc gcatcgccaa acacccaaac ggtagccatt cccatgacct gatgctgtgc
    26521 gatgtggcaa tgcatcatcc aagcaccgat gttttcctcg gtgatgcgaa ttcgccaagc
    26581 tctccaacca gcggtgtgat gtggaacacc cttgacagca tatcggtaga ggttcgttgt
    26641 gtctcgtaga acaggggtga agttttcgaa atgagcttcg ttttcggttg cgttgtaagt
    26701 accattgcca gagccgagat cgtaaacgtg atatccatgg acgtgcatag gatggtagtc
    26761 ccagccgcct gtaggaccgt tgttgttctc ccagactatg tccaggactt caccaacctt
    26821 ggcggggaat gccttggttt ctggatcgaa gccatggtgc tccaaagcaa gagtatagtt
    26881 gggagtcgtg ccattctcgt aaatctgaat gagatatggg acttggcgac gctcagcttg
    26941 aacgttttct ttccaaggta gaccgttttg gctgattgtt gttagcaaat tgtgacataa
    27001 tggtatgaat ttgtaactta cgcccaggct actgtgccat tcaacgttcc attaacatag
    27061 gctccagtag tgagtatttg gttaatctga ataacaacag ttctcgttac ttctgacaac
    27121 ttgggaaatg cttggttgtt cttctccgat aagccttcca gggcgtactc gaggtagtca
    27181 gcagtgctat tggacagttc gatgggtgat gtctcaggta gtgattttgg aagcttctgg
    27241 tttttatcac accgatactt gagtaaggcg tatccgctga tcactttcgg tcgatcgcga
    27301 ctttcgtacc ggatccaata ctgagacttg tcacctccac aaacctcttt cgaagttttg
    27361 gttttcatga ggtaactgta gcgctgaccg ggtgacacct ggacatgatc gatcttagca
    27421 ggctttgtgt atgatccgtc agcctcaatg actgtaaggt tttcgtgatc ttcaatgcca
    27481 agcttgatca tagacaatgc tgtagcactg atgaatcgaa gccggtaggt ttttccgggg
    27541 tcaacgtgaa cgacatgagg catgcagctc gagtctggtg cttcgtagaa actcttgttg
    27601 ccgctgttcc cttggatagt aatagcttga ggttctccag accacttgaa ggggtctgct
    27661 aacaggccct gttctatcac ttcatcctcg gcagcgtagt tatcgcctac cagaagaggg
    27721 atgtctccat cgtacttgta ctctggcttc cgagcgtctc ggactatcaa agctccaaag
    27781 gcagtcacga tctgaaagcc gacatgcgaa tgatagaagt aagatcctgc gtctccaatc
    27841 tctggtcgaa tctcataatc gaagaattgg ccggccggga tgggccattg actgacgagg
    27901 ggagtaccat cagagaaagg tgcggctcgc tgactcagac catgccagtg cttatgttgt
    27961 cagctttgaa gggaagaggg agtgcgtgta agcttacgac tgtgacgttg ttgtctggaa
    28021 ttttgttgta aactcgaatc caagtcgtct gttcctcttg gaggtatatc gtcggtccgg
    28081 gagaggtgcc attgaagacg attgacgatc ttgacacgca gttgatctta atatcgtcta
    28141 aagttgcttc tagaacgtag tcaggcttga aggtatcatc gtgcaccttg tattcagcga
    28201 atgctccagc cacgaatggc aacaaggcca gaaaacgaaa caacattttg cagatagcag
    28261 taccgatggc aaaggaaatt tagcattgtt gcagcgagac atgattaata taaatatctt
    28321 gttttgtctc ttccatgttc tatgctatgc agggattaat ctcccagggt cgagaccgtg
    28381 acacctaaca agctttcagc ccgcccgtcc ggcttcgtcg gggtgagcac taacgcatga
    28441 tcgcgccaaa agcagacagt ggctttgcca aaaaaaaaga attaccccct agaaaatgac
    28501 gtccacgatc gtcgtcgtcg gtcagcattt aacgaggcca cggggctcag acaaggcaca
    28561 aagccaacag ccttgccggt gtgttttgga gcgaaggatc agaaggattc aaactcgaga
    28621 tggcaagctg gggatgttcc acggttgagg gtgatagaca gcttgtatag cttgttcagg
    28681 ttagaagggg tccacgtcat gcacattgat tggtaaaatt agggggctgt aagtttatct
    28741 agacgctatc ttagaattgc gaagtgacaa ttgacaactg ccgagttggg ctctctcgct
    28801 ccgccatcaa ctggagtgag gaaagtcaat ggcaacgttg accgaattaa tcttttactt
    28861 cccaattagt tcaatgtggc tgcggatatt ggaattgctg cgttagtaca gagtattaga
    28921 catacacatg gtaagcacat ggcacactct gcacgctatt ccattggcgc aacgggatct
    28981 atgcatggcg caggtatgtg a
//
