BGC0002710 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002710 (Metarhizium robertsii ARSEF 23)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	33,332	metachelin C/metachelin A/metachelin A-CE/metachelin B/dimerumic acid 11-mannoside/dimerumic acid	NRPS:Type I	100%

BGC0002710 - Region 1 - NRPS

Download region GenBank file

Download region SVG

Location: 1 - 33,332 nt. (total: 33,332 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 33,333
Label		BGC0002710

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002710	1.00	NRP	metachelin C, metachelin A, metachelin A-CE, metachelin B, dimerumic acid 11-mannoside, dimerumic acid	Metarhizium robertsii ARSEF 23
BGC0001249	0.38	NRP	dimethylcoprogen	Alternaria alternata
BGC0000900	0.36	Other	ferrichrome	Aspergillus oryzae
BGC0000348	0.31	NRP	ergovaline	Epichloe festucae var. lolii
BGC0001261	0.26	NRP	AM-toxin	Alternaria alternata
BGC0002166	0.26	NRP	peramine, intermediate 1, intermediate 2	Metarhizium rileyi
BGC0002164	0.25	NRP	peramine	Epichloe festucae
BGC0002157	0.24	NRP, Alkaloid	(-)-ditryptophenaline	Aspergillus flavus
BGC0001517	0.24	NRP	asperphenamate	Aspergillus terreus NIH2624
BGC0001561	0.24	NRP	curacomycin	Streptomyces curacoi

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002710	1.00	NRP	metachelin C, metachelin A, metachelin A-CE, metachelin B, dimerumic acid 11-mannoside, dimerumic acid	Metarhizium robertsii ARSEF 23
BGC0001249	0.70	NRP	dimethylcoprogen	Alternaria alternata
BGC0000900	0.69	Other	ferrichrome	Aspergillus oryzae
BGC0000348	0.64	NRP	ergovaline	Epichloe festucae var. lolii
BGC0001261	0.60	NRP	AM-toxin	Alternaria alternata
BGC0002166	0.59	NRP	peramine, intermediate 1, intermediate 2	Metarhizium rileyi
BGC0002164	0.59	NRP	peramine	Epichloe festucae
BGC0002157	0.58	NRP, Alkaloid	(-)-ditryptophenaline	Aspergillus flavus
BGC0001517	0.58	NRP	asperphenamate	Aspergillus terreus NIH2624
BGC0001561	0.57	NRP	curacomycin	Streptomyces curacoi

Similar known gene clusters from MIBiG 4.0

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 4908 - 33332:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

MAA_05335

AMP-binding (52..462): X

nrpys: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: HCLHIASTCK
Nearest Stachelhaus code(s):: Z-ahmohOrn FGLHIASTCK (88% 8Å match)
Stachelhaus code match:: 80% (moderate)

MAA_05334

AMP-binding (92..492): X

nrpys: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVDHGGAVGK
Nearest Stachelhaus code(s):: Z-ahmohOrn DVDGGGGIGK (68% 8Å match)
Stachelhaus code match:: 70% (weak)