BGC0002731 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002731 (Aspergillus nanangensis)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	51,887	nanangenine A/nanangenine B/nanangenine C	PKS	100%

BGC0002731 - Region 1 - T1PKS

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Location: 1 - 51,887 nt. (total: 51,887 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 51,888
Label		BGC0002731

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002731	1.00	Polyketide	nanangenine A, nanangenine B, nanangenine C	Aspergillus nanangensis
BGC0002266	0.55	Terpene, Polyketide	calidoustene A, calidoustene B, calidoustene C	Aspergillus calidoustus
BGC0002610	0.40	Terpene	stellatic acid	Aspergillus stellatus
BGC0002609	0.36	NRP, Polyketide	ochratoxin A	Aspergillus welwitschiae
BGC0001749	0.35	Polyketide	epipyriculol	Pyricularia oryzae 70-15
BGC0002219	0.32	Terpene	(-)-(R)-nephthenol	Stereum hirsutum FP-91666 SS1
BGC0000677	0.32	Terpene	cyclooctatin	Streptomyces melanosporofaciens
BGC0000798	0.31	Saccharide	dhurrin	Sorghum bicolor
BGC0002227	0.31	NRP	AKML B, AKML D, AKML A, AKML C	Aspergillus luchuensis IFO 4308
BGC0002729	0.31	Polyketide	sordarial	Neurospora crassa OR74A

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002731	1.00	Polyketide	nanangenine A, nanangenine B, nanangenine C	Aspergillus nanangensis
BGC0002266	0.81	Terpene, Polyketide	calidoustene A, calidoustene B, calidoustene C	Aspergillus calidoustus
BGC0002610	0.72	Terpene	stellatic acid	Aspergillus stellatus
BGC0002609	0.69	NRP, Polyketide	ochratoxin A	Aspergillus welwitschiae
BGC0001749	0.68	Polyketide	epipyriculol	Pyricularia oryzae 70-15
BGC0002219	0.65	Terpene	(-)-(R)-nephthenol	Stereum hirsutum FP-91666 SS1
BGC0000677	0.65	Terpene	cyclooctatin	Streptomyces melanosporofaciens
BGC0000798	0.65	Saccharide	dhurrin	Sorghum bicolor
BGC0002227	0.64	NRP	AKML B, AKML D, AKML A, AKML C	Aspergillus luchuensis IFO 4308
BGC0002729	0.64	Polyketide	sordarial	Neurospora crassa OR74A

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 43440:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

FE257_006541

PKS_AT (554..871): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 70.8%; 2-Methylbutyryl-CoA: 62.5%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 76.9
Methoxymalonyl-CoA: 64.9
Malonyl-CoA: 42.6
Propionyl-CoA: 40.9
Ethylmalonyl-CoA: 25.0
Isobutyryl-CoA: 24.7
2-Methylbutyryl-CoA: 23.9
Benzoyl-CoA: 18.7
trans-1,2-CPDA: 17.8
fatty_acid: 16.3
CHC-CoA: 12.7
3-Methylbutyryl-CoA: 7.9
Acetyl-CoA: 1.4
inactive: 0.0