BGC0002732: WS 79089B biosynthetic gene cluster from Streptosporangium roseum DSM 43021
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Location: 4,607,917 - 4,646,430 nt. (total: 38,514 nt).
This entry is originally from NCBI GenBank CP001814.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002732
Short description WS 79089B biosynthetic gene cluster from Streptosporangium roseum DSM 43021
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
CP001814.1
4607917 - 4646430
via Knock-out studies
Compounds
  • WS 79089B
  • benaphthamycin
  • WS 79089D
  • WS 79089A
  • WS 79089C
Species Streptosporangium roseum DSM 43021 [taxonomy]
References
Chemical products information
WS 79089B Evidence:
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Chemical database entries
NPAtlas
benaphthamycin Evidence:
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Chemical database entries
NPAtlas
WS 79089D Evidence:
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WS 79089A Evidence:
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Chemical database entries
NPAtlas
WS 79089C Evidence:
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Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • Sros_4137
  • ACZ87041.1
 4607917 - 4608708 (-) putative transcriptional regulator, TetR family
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    • Sros_4138
    • ACZ87042.1
    		 4609240 - 4610466 (+) monooxygenase, FAD-binding protein
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      • Sros_4139
      • ACZ87043.1
      		 4610578 - 4610886 (-) hypothetical protein
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        • Sros_4140
        • ACZ87044.1
        		 4611029 - 4611484 (-) hypothetical protein
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          • Sros_4141
          • ACZ87045.1
          		 4611490 - 4612347 (-) Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase-like protein
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            • Sros_4142
            • ACZ87046.1
            		 4612424 - 4612804 (-) hypothetical protein
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              • Sros_4143
              • ACZ87047.1
              		 4612804 - 4613541 (-) short-chain dehydrogenase/reductase SDR
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                • Sros_4144
                • ACZ87048.1
                		 4613700 - 4614065 (-) hypothetical protein
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                  • Sros_4145
                  • ACZ87049.1
                  		 4614658 - 4615398 (+) short-chain dehydrogenase/reductase SDR
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                    • Sros_4146
                    • ACZ87050.1
                    		 4615413 - 4617101 (+) All-trans-retinol 13,14-reductase
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                      • Sros_4147
                      • ACZ87051.1
                      		 4617104 - 4617988 (-) 3-hydroxyisobutyrate dehydrogenase family protein
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                        • Sros_4148
                        • ACZ87052.1
                        		 4618341 - 4618667 (+) hypothetical protein
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                          • Sros_4149
                          • ACZ87053.1
                          		 4618660 - 4619112 (+) hypothetical protein
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                            • Sros_4150
                            • ACZ87054.1
                            		 4619112 - 4620380 (+) 3-oxoacyl-(acyl-carrier-protein) synthase II
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                              • Sros_4151
                              • ACZ87055.1
                              		 4620377 - 4621597 (+) 3-oxoacyl-(acyl-carrier-protein) synthase II
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                                • Sros_4152
                                • ACZ87056.1
                                		 4621609 - 4621869 (+) conserved hypothetical protein
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                                  • Sros_4153
                                  • ACZ87057.1
                                  		 4621930 - 4622412 (+) hypothetical protein
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                                    • Sros_4154
                                    • ACZ87058.1
                                    		 4622409 - 4622882 (+) hypothetical protein
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                                      • Sros_4155
                                      • ACZ87059.1
                                      		 4622932 - 4623663 (+) NAD dependent epimerase/dehydratase family protein
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                                        • Sros_4156
                                        • ACZ87060.1
                                        		 4623663 - 4625288 (+) PheA/TfdB family FAD-binding monooxygenase
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                                          • Sros_4157
                                          • ACZ87061.1
                                          		 4625321 - 4625989 (+) putative transcriptional activator, TenA family
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                                            • Sros_4158
                                            • ACZ87062.1
                                            		 4626186 - 4627712 (+) conserved hypothetical protein
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                                              • Sros_4159
                                              • ACZ87063.1
                                              		 4627894 - 4629234 (+) sodium/hydrogen exchanger
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                                                • Sros_4160
                                                • ACZ87064.1
                                                		 4629357 - 4630457 (+) hypothetical protein
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                                                  • Sros_4161
                                                  • ACZ87065.1
                                                  		 4630503 - 4631915 (+) putative tryptophan halogenase
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                                                    • Sros_4162
                                                    • ACZ87066.1
                                                    		 4632201 - 4633202 (-) Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase-like protein
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                                                      • Sros_4163
                                                      • ACZ87067.1
                                                      		 4633647 - 4634504 (+) Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase-like protein
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                                                        • Sros_4164
                                                        • ACZ87068.1
                                                        		 4634518 - 4635765 (+) putative monoxygenase
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                                                          • Sros_4165
                                                          • ACZ87069.1
                                                          		 4635780 - 4636793 (+) O-methyltransferase family protein
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                                                            • Sros_4166
                                                            • ACZ87070.1
                                                            		 4636944 - 4637789 (+) nucleotide-diphosphate-sugar epimerase
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                                                              • Sros_4167
                                                              • ACZ87071.1
                                                              		 4637801 - 4638835 (-) O-methyltransferase family protein
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                                                                • Sros_4168
                                                                • ACZ87072.1
                                                                		 4639013 - 4639207 (+) ferredoxin (4Fe-4S)
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                                                                  • Sros_4169
                                                                  • ACZ87073.1
                                                                  		 4639278 - 4641137 (+) Asparagine synthase (glutamine-hydrolyzing)
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                                                                    • Sros_4170
                                                                    • ACZ87074.1
                                                                    		 4641158 - 4641757 (+) Nitroreductase-like protein
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                                                                      • Sros_4171
                                                                      • ACZ87075.1
                                                                      		 4641816 - 4643288 (+) NADPH-dependent glutamate synthase beta chain
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                                                                        • Sros_4172
                                                                        • ACZ87076.1
                                                                        		 4643668 - 4644024 (-) hypothetical protein
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                                                                          • Sros_4173
                                                                          • ACZ87077.1
                                                                          		 4644047 - 4644436 (-) hypothetical protein
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                                                                            Biosynthesis information
                                                                            Annotation changelog

                                                                            Entry version: 2

                                                                            Date
                                                                            Changes
                                                                            Submitters
                                                                            Reviewers
                                                                            2022-10-07
                                                                            Removed compounds: FR901533.
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            2022-10-07
                                                                            Added compounds: WS 79089B, benaphthamycin, WS 79089D, WS 79089A, WS 79089C.
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            2022-10-07
                                                                            Added NPAtlas links to compounds: WS 79089B, benaphthamycin, WS 79089A, WS 79089C.
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                            Entry version: 1

                                                                            Date
                                                                            Changes
                                                                            Submitters
                                                                            Reviewers
                                                                            2022-09-15
                                                                            Entry added
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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