LOCUS       BGC0002750             21234 bp    DNA     linear   BCT 08-SEP-2017
DEFINITION  Streptomyces sp. CLI2509, complete sequence.
ACCESSION   BGC0002750
VERSION     BGC0002750
KEYWORDS    .
SOURCE      Streptomyces sp. CLI2509
  ORGANISM  Streptomyces sp. CLI2509
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7088673)
  AUTHORS   Ruzzini,A.C., Wyche,T., Schwab,L., Currie,C.R. and Clardy,J.
  TITLE     Tryptorubin A, a polycyclic peptide from a mushroom-derived
            Streptomycete
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7088673)
  AUTHORS   Wyche,T., Ruzzini,A.C., Schwab,L., Currie,C.R. and Clardy,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-MAY-2017) Biological Chemistry and Molecular
            Pharmacology, Harvard Medical School, 240 Longwood Avenue, Boston,
            MA 02115, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 04-08-2015
            Genome Coverage                   :: 253x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/04/2017 12:11:21
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            Annotation Method :: Best-placed reference protein set; GeneMarkS+
            Annotation Software revision      :: 4.1
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 6,238
            CDS (total)                       :: 6,152
            Genes (coding)                    :: 5,847
            CDS (coding)                      :: 5,847
            Genes (RNA)                       :: 86
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 305
            Pseudo Genes (ambiguous residues) :: 0 of 305
            Pseudo Genes (frameshifted)       :: 225 of 305
            Pseudo Genes (incomplete)         :: 94 of 305
            Pseudo Genes (internal stop)      :: 23 of 305
            Pseudo Genes (multiple problems)  :: 30 of 305
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: False
            Run date                          :: 2025-08-15 22:30:49
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 954735
            Orig. end                         :: 975969
            ##antiSMASH-Data-END##
            Bacteria and source DNA available from Cameron R. Currie.
            Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21234
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="atropopeptide"
                     /region_number="1"
                     /rules="atropopeptide_p450"
                     /subregion_numbers="1"
                     /tool="antismash"
     cand_cluster    1..21234
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="atropopeptide_p450"
                     /kind="single"
                     /product="atropopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21234
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11234](-)"
                     /cutoff="10000"
                     /detection_rule="atropopeptide_p450"
                     /neighbourhood="10000"
                     /product="atropopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11234)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="atropopeptide_p450"
                     /neighbourhood="10000"
                     /product="atropopeptide"
                     /protocluster_number="1"
     gene            complement(1305..2252)
                     /locus_tag="CAC01_03945"
     gene            2548..3168
                     /locus_tag="CAC01_03950"
     gene            3276..4781
                     /locus_tag="CAC01_03955"
     gene            4930..5772
                     /locus_tag="CAC01_03960"
     gene            complement(5855..7090)
                     /locus_tag="CAC01_03965"
     gene            complement(7169..8176)
                     /locus_tag="CAC01_03970"
     gene            8316..9179
                     /locus_tag="CAC01_03975"
     gene            9453..10010
                     /locus_tag="CAC01_03980"
     gene            complement(10001..11047)
                     /locus_tag="CAC01_03985"
     CDS             complement(10001..11047)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     atropopeptide: atropopeptide_p450"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (MITE)
                     MITE0000172: Biaryl bond formation (66% identity)"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007820080.1"
                     /locus_tag="CAC01_03985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome"
                     /protein_id="ASY31956.1"
                     /sec_met_domain="atropopeptide_p450 (E-value: 1.2e-183,
                     bitscore: 597.0, seeds: 287, tool: rule-based-clusters)"
                     /sec_met_domain="p450 (E-value: 6.3e-19, bitscore: 55.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSHTQTRPHERETLFAPPLEALLRDHLGADLFRPEPDTVGVAGP
                     ALVDRILAARPAGKTERPTFKPLLGRAIPHQQAATQMQAIGHDVRAALKREAPRDPDLS
                     GPWPHVGHVYLRDLILGGDPRRLRVLMNRALELTPKLTWTVIAAGAALPAPRRRTGTTR
                     LGALSTGAATYQERRYAMGLYRRTAAPVCFTISTLVANALWLGAPFAAEVPSRHLVHES
                     LRLLPPSWNILRNSSPEYPVIDARIAPADDVLVLPFLSHRDPALWENPEEFRPERWEEL
                     DPERVPGYLPFGHSSERCWGRHMVMPLAEMLLDMIRSSGLVVDPGQRTARVPLTGLMGV
                     DQVRLVQP"
     subregion       11047..11234
                     /aStool="mibig"
                     /contig_edge="False"
                     /label="ribosomal"
                     /subregion_number="1"
                     /tool="antismash"
     CDS             complement(11157..11234)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     atropopeptide: atropopeptide_precursor"
                     /gene_kind="biosynthetic"
                     /locus_tag="trpA"
                     /sec_met_domain="atropopeptide_precursor (E-value: 1.0,
                     bitscore: 1.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MRLLFSLKNKMSQQKSLKAHAWYIWY"
     gene            11814..13637
                     /locus_tag="CAC01_03990"
     gene            13843..14628
                     /locus_tag="CAC01_03995"
     gene            complement(14708..15424)
                     /locus_tag="CAC01_04000"
     gene            complement(15427..15738)
                     /locus_tag="CAC01_04005"
     gene            15962..17191
                     /locus_tag="CAC01_04010"
     gene            complement(17291..17791)
                     /locus_tag="CAC01_04015"
ORIGIN
        1 gcgagcaggg tgtggccgag gcccgtgacc ccgccgccga tcaccacgag tcccgggttg
       61 aagaagctga cgagcgaggc gatcacctgt ccggtgcggt tgcccccgga gcggatgagg
      121 tcgagggccg cgggatcgcc cgccgccgct gccgccgcca cgtcggccgc gttgagcgtg
      181 ccctgcgcgc cgaggcgttc ggcgagcacg ggcgagcggc cctcgcgggc cgcgtcctgc
      241 gcgtcgcggg cgagcgccgc accgctgaag tgggcttcca ggcagcccct gttgccgcag
      301 gcgcaggacc tgccctcggg ctccacctgg atgtgtccta tgtcgcccgc gctgcccgtg
      361 gtgccccggt agacctcgcc gccgacgacg atgccgcagc cgatgccggt gccgatcttg
      421 acgcacagga agtcgcctgc cgagcgggcg actcctgcgt gctgctcgcc gagcgccatg
      481 aggttcacgt cgttgtcgac catgacgggg cagccgagtt cctggctcag gacctcgcgg
      541 acggggtagc cgtcccagcc gggcatgatc ggaggcgcca cgggaacgcc ctcggggaag
      601 cggaccggtc ccgggacgcc gataccggcg ccgtcgaagc cgtccgcgaa gcccgatgcc
      661 cgcaacttcg ccgccatggc gaggacttgc tcgaagaccg cgaccggtcc ctcgcggacg
      721 tccatggggt gcgtgatgtg ccccaggatc tccagctcgg cgttggtcac ggcgacgtcg
      781 atcgaggtgg ccccgatgtc cacgccgagg aaacggagtc cgggcgcgag ccggatgttg
      841 tgcgagcgac ggccgccgcg ggacgcggcg agcccgtcgg ccacgacgag cccggtctcc
      901 aggagccggt ccacctcgac ggccagcttg gaccgcgaga ggtcgacctg gtcaccgagc
      961 tgggcgcggg agttggggcc cccgtcgcgc agcagtcgca gcaaccgggc ctgatgcgtg
     1021 ttggcgggtc gtgctgtcat gcgtctcacg cgcccctccc cgcctcaccg gctgtccgat
     1081 tccctcgccg ccgcccgccg ccgcggcccg cttgcggcgg gtcgtggcgt tctcgcgctc
     1141 acgggcgttc gcgctttcga cgtggaacgt agcagtgggc taccggaagg ggaaggactt
     1201 gcgcgggaat tggcccctac tttctcccgc ctcaggacaa aggagcgggc ggcgtgggtc
     1261 aatgagcgcg cggggcgggc gaatcacccc ggtgggaggg ggtttcaggg gcagcggacg
     1321 acctgacccc cgtacgagag gtttccgccg aagccgaaga ggaggacggg gtcgccgctg
     1381 ctcagctcgc cgcgctcgac gagcttggag aaggcgagcg ggatgctcgc ggccgaggtg
     1441 ttgccggagt ccacgacgtc cttggcgatc acggcgttga cggcgccgag gcggcgcacg
     1501 acgggttcca cgatgcgcag gttggcctgg tggagcacga cgcccgcgag gtcctcgggg
     1561 gtgagcccgg cgcgctcgca gacctgccgg gcgatggcgg gcagctgggt ggtggcccag
     1621 cggtagacgg tctgcccctc ctgcgcgaag cgcgccgggg tgccctcgat acgtaccgcg
     1681 ttgcccatcg ccgggttcga gccccacagc accgggccga tccccggctc ctcgcccggc
     1741 gcggtcgcct cgacgacggc ggcgcccgct ccgtcgccga cgaggacgca ggagctgcgg
     1801 tcggtccagt cggtgacggc ggacatcttg tcggcgccga tgacaagggc ctgccgggcg
     1861 ctgcccgcgc ggacggtggc gtcggcgagg gcgagggcgt gcgtgaagcc cgcgcagacg
     1921 acgttgacgt cgagcacggc gggtgagggc atcccgaggc gcgcggcgac gcgggcggcg
     1981 gtgttgggcg agcggtcgac ggccgtggag gtcgcgacga ggaccatgtc gacggcgccg
     2041 ggggtgagcc cggcggcggc gagcgccttc gcgcccgcgt aggcggccag ctcgtcgacc
     2101 ggttcgtcgt cacccgcgat gtgcctggtc ctgatgccga cgcgggacgt gatccacgcg
     2161 tcgttggtgt cgaccatgcc ggcaaggtcc tcgttggtga gcacccggcc gggctggtag
     2221 tgaccgagcg cgacgatccg tgaaccgttc atgggggtct tgccctccgt agccgtgttc
     2281 cgtagccgtg agacggattg ttccagcgtg atcacttacc gacgggtacg gaggtgggta
     2341 aagcgacagg attcgggcga cgggcttgga gagttcaccc agaaccacgg gacaccaggg
     2401 gcgtgcgggg tgaaagaggg gcgcgaagga gtgcggaaac gctcccgcgc gggaccggcg
     2461 gggccacttt ggaaacgttt gcgtttttcc cggcgggcgg gctaccgtga cgtccgtaaa
     2521 aacgtgagcg tttcttttcc gggggtcgtg gtgagcgagg agtcggggga cggcgcgcgc
     2581 ccggccgggg cgcgtccgcc cgtgcggcgt ccccggctca ccccggagcg ggaggacgag
     2641 ttcctctcgg ccgccctcgc cgtcgtacgg gagacggggt acgaggcgct gaccatggaa
     2701 ggcgtcgcgg cccgcgccca gtgcggcaag gcgacgctct accggctcta ccgcaccaag
     2761 cagcacctcg tggccacggc gctctcgcgc acccggcccg cgcgcgggct gccgctcgac
     2821 acgggctcgc tccggggcga tctgctcgcc gccgcccggc gggcgtcctc cgagttcgag
     2881 gactcgacga cgctcgtctg ggcggtcgcg cacgcctcca tcgaggaccg ggccctgcac
     2941 gacgcgctgc ggctcgcctt catcgacccg gagacggccg agctgaccgc cgccgtggac
     3001 cgcgccgtcg cgcgcgggga gctgtcgcac cgcccggccg ccgcgcggca gctcagcggg
     3061 ctcctcttcg gtgccgcgct cgtgcacagc ctcgacggcc ggaccggccc ctcgggactc
     3121 gaggccctcg tggaggacgt cctcctcccg gcgctgctgc acagctgacc ggtccgggcg
     3181 gccggaggag tccgcccgcg cccggccgct ccctcctgtt cccctcccac ccgcgacagc
     3241 ccgctcctcc cctctcccac gcaaggaagt accgcatgtc ctcgcccgca accggcgctc
     3301 cggcacgtcc cggaaccgcc ggaaccgcct ccgggcccgt gccgcaccgc tggctgatca
     3361 tggtcttcat cgccgtggcc cagctgatgg tggtcctcga cgcgacgatc gtgaacatcg
     3421 cgctgcccac cgcgcagcgc gacctcggct tctccgacgc cgaccggcag tgggtcgtca
     3481 cggcctactc gctcgccttc ggctcgctgc tgctcctcgg tggccgcgtc gccgacctct
     3541 tcggccgcaa gaacgccttc ctcataggtc tcgtcggctt cgcgctcgcc tccgcgctcg
     3601 gcggtgccgc cgggagcttc gaggtcctga tcgtcgcgcg cgccgtgcag ggcctcttcg
     3661 gcgccctgct cgcgcccgcc gccctctcgc tgctcacgac gaccttcacc gacccggccg
     3721 agcgcggccg ggccttcggc atcttcggcg cggtcgccgg gtccggcgcg gccctcgggc
     3781 tgctcctcgg cggcatcctg accgagcacc tcaactggcg ctggaccctg tacgtcaaca
     3841 tcgccttcgc ggcgatcgcc ttcgtcggcg gcctgctcct gctgcgccgt accgcccgcg
     3901 accgcacgaa gaagctcgac gtgccgggga cgctgctcgc gagcgcgggg ctcttctgcc
     3961 tcgtctacgg cttcgcgaac gccgagacgc acacgtggtc gtcggtcagc acctggggct
     4021 tcctcgtcgc gagcgccctc ctgctcgccg ccttctgctt ctggcagacg cgtaccgccc
     4081 acccgctgct gccgctgcgc atcctgctgc accgcgaccg gggcgccgcc tacaccgcga
     4141 tgctcgtcgc gggcgcgtcg atcttcggca tcagcctctt cctgacgtac tacctccagc
     4201 aggtcctggg gctgtccccg gtgcggaccg ggctcgcgtt cctgccgatg agcggcgcca
     4261 tcatggtcac ggcgacgacg ggcgcgagcg tcctgctccc ccgcttcggg ccgaagctcg
     4321 tggtgagcgc cgggatgctg ctcggcggga tcggcgcgct gtggctctcg cggctggacg
     4381 tggacagctc gtacgcgggc cacgtgctgc cgccgctcgt catcgcgggg ctcggcatgg
     4441 gtgccgtgat ggcgaccgcg atgagccagg ccacggcggg agtcgcgcac agcgacgcgg
     4501 gcgcggcggg cgcgctcgtc aacaccatgc agcaggtcgg cggttcgctc ggcacggcgc
     4561 tgctcaacac gatcgtcgcg agcggcgctg ccgactacct cgccgcccac gacgcgcgcg
     4621 acccgaaggc gcggctcgcc gccggggtgc acggctactc cgacgcgtac gtgtggacgg
     4681 cggtcttctt cgccgtgggc ctcgtcgccg ccggtctcct cttccgccgc cgacgcgcgc
     4741 accgcgccgg gcagcacgcg gcgccggtgg tccacatgtg aggacacggg gagggggccg
     4801 ccgccgagcg gccccctccc cgtatcgtcc ccacgagggc cgtggcacgc tcgtaccgac
     4861 gtgccaccgc acgcatgggg cgggcggggg ccgcggcgca cgggtacgga cggaaagggc
     4921 gggccgctca tgggacgcgt gacggaacgg cggcgggtca cccgcgtacg ggcgggcgtc
     4981 gtctcggcgc gccccgacac gctcgtcgcc gaggaacccc tcgaaatccg cctcgcgggc
     5041 aagccgctcg ccatcacgat gcgcaccccc ggcgacgact tcgcgctcgc cgccggtttc
     5101 ctcgtgagcg agggcgtcct cgcctccgcc gacgacgtgc gctcgatcgt gtactgcgcc
     5161 ggggcgaccg acgacggctc gaacacgtac aacgtcgtgg acgtgcggct cgccgacgga
     5221 gtggccctcc ccgacttcac cctggaacgg aacgtctaca cgtcctcgtc gtgcggcctg
     5281 tgcggaaagg cgagcctgga cgcggtccgt acgacgaccc gccacccgct cgccgacacc
     5341 ccgcccctgc gcctctcccc cgctctcctc tccgccctcc ccgaccgcct ccgcgccgcg
     5401 cagcgcgtct tcgaccgcac gggcggcctc cacgcggcgg cgctcttctc cgagacgggt
     5461 gaactcctcg acatccgcga ggacgtgggc cgccacaacg cggtcgacaa actcgtgggc
     5521 cgcgccctca ccgacgcccg cctccccctg agccgcgcga tcctcctggt ctcgggccgc
     5581 gcctccttcg aactcgccca gaaggcggcc atggcgggca tcccggtcct ggccgccgtc
     5641 tcggccccct cctccctggc ggtggacctg gcggcggaga cgggaatgac gctggtgggg
     5701 ttcctgcggg gggagtcgat gaacgtgtac gcgggagagg agcggctggt gctggagggg
     5761 gcggaggtgt gagcgccgct tgagggacgg acggggcgcg gggatggggc gagccgcgca
     5821 ccgggccgtg ccgcacggcc cgtggccgca cggcctagcg tgatcgctcc tcgcgccgct
     5881 tcgccgccgc cgggcgcgcc gccgggatcg acgcccccgc gcgcggtgcc gttgccgggg
     5941 agatcgctgc cgcgaggagc atcagggcca ggaccgggag cattgccgcg cgaaggccgt
     6001 tgtggtcgcc caggaagccg aggcacgggg ggcccgccag gagggccacg tagccgatgc
     6061 gggaggtcag ggctacgcgg gccgccgtgt ccgggcccga ttcgcccgcc gctgagaggg
     6121 ccagcgggaa gcccagggag gtgccgaggc cccacaggag gaccgcgcag cccgccgtcg
     6181 ccgggttgtc gacgaaggag accagggcga tgcccagcgc cgtgaggagt gctccggcgc
     6241 ccaggaccgt cgcgcggccg aagcgcgtga ccaccgggcc cccggcgaag cggcccgccg
     6301 ccatcgtcgc cgcgaaaccg gtgtagacga gcgagccgag ccccgcgggc atgtcgtggc
     6361 cgtcgaccat caggagcggg agccagtccg tcgccgcccc ctccgcgagg gtcacgccga
     6421 agaccacgcc gccgatcagg agcagtcgcg ggtcgaggtg gaggcgccgt tcccgtaccg
     6481 tcccggcctc gtccgtgctc gtggcgccga tgccgggtcg caggcccggg atcgcgtacg
     6541 cgaagaggcc gagcacgagg agcaggacga gggccaggtg ccacggcacg gggaagccga
     6601 ccgccgcccc caccacaccg aggcccgcgc ccaccaccgt gccgaggctg tagcagccgt
     6661 gcatcgcggg caggaccggg cgccccatct gccgctcgac gtggacgccc gcgacgttgc
     6721 tggccacctc cgagagcccc acccccgcgc cgatgagcag gaggccgcac gccacgagga
     6781 gcgccgccga cagccccgta ccgagcgcca ccaccccgac gcccgccagc acgagcgtca
     6841 tgcccgcgat gacgacggga cgggtcgcga agcgggccac gaggccgccc gccgccagga
     6901 tgccgagcat cgagccgatc gacatgccga agagcacgag tcccatctcg gcggtcgagg
     6961 cgccgaggcc gtcgcgtacg tcgggggtgc gggtgaccca cgtggcgagc gagacgccgg
     7021 gtatcgcgaa gcacaggttg agggcgacgc ggtggcggcg gaccagcggg tccacgggcg
     7081 cggaatccat ggcgtgcggg tctccggagg gcggcgcggc gggggacgta ctcccgcacc
     7141 ctacgcagcc ccggccgctc cccctcgttc agcccccgcc gctccccgtc acggccgcca
     7201 cctcggcgct ctccgccgga gccgtctccg ccgcgcgcct gcgggcgatc accgcgcaca
     7261 ccatgagctg catctggtgg aacaccatca gcggcagcac cgcgagcgag gcgtgggcgc
     7321 cgaagaggac gctcgccatg ggcaaccccg aggcgaggga cttcttcgag cccgcgaact
     7381 ggatcgcgac gcggtcggcg cgggggaagc cgagccgccc ggcgccccac cacgtgaggc
     7441 cgagcatcgc ggcgaggagg accgcctcgg cgaggagcag ggcgaggagg cgcggcacgg
     7501 tgacctggtg ccagatgccc cgcaccatgc cctcgctgaa cgccgtgtag acgacgagga
     7561 ggatcgagcc ccggtccacg tacccgagca ccttcttgtg ccgggtcagg aagccgccga
     7621 cccagcggcg caggaactgg ccggcgagga acggcaggag gagctggacg acgatcttgc
     7681 cgagcgaggc cgccgagaag ccgccgccgc tgtcgccgag gagcgcggcg gcgagcaggg
     7741 gtgtgaggac gatgccgaag agcgaggaga aggagcccgc gcagatcgcg gcgggcacgt
     7801 tcccgcgcgc gagcgaggtg aaggcgatcg aggactggat cgtggagggc acgagggtga
     7861 ggaagaggaa gcccgtgaag aggtcggggc tcagcagcca ggggcgcagt gcgtaggcgg
     7921 cgaggccgag cagcgggaag acgacgaacg tcgcggcgag gacggtgacg tgcagccgcc
     7981 agtgccgcag cccgtcgagc gcctcggcgg tggacaggcg cgccccgtac aggaagaaga
     8041 gcagtgccac ggcggccgtc gacgcccccg atacgccgct cgcggcgccg ccgcgcgcgg
     8101 ggagcagcgc ggcgagcagg acggtgccga ggagcgacag gatgtacggg tccagcggga
     8161 gccggaggcg tttcatggcg gaggccgtcc tcggggtgta cggggaagga tgggggcgcc
     8221 atcgatcgtg ccgcacccgg ccgctgatcg ggaaccccgt acaccactct gactgttatc
     8281 gcgcccgacg atgaccgtga ctacactccc ccaccgtgta cgagccctcc cacctgcgca
     8341 ccttcctcac cgtggcgcag acgctcagct tcacgcgggc cgcgcagcgg ctcggggtgc
     8401 ggcagtcgac ggtgagccag cacgtgcggc gcctggagga gcagaccggg aggccgctct
     8461 tcgtccggga cacgcactcg gtcgcgctca ccgaggacgg cgaggcgatg ctcggcttcg
     8521 cgcggcgcct cctcgcggtg caggagcagg cggcggcgca cttcgcgggg acgcggctgc
     8581 gcgggcgact gcgcttcggg gcctccgagg acttcgtgct gacgcggctc ccggagatcc
     8641 tggagtcctt ccggcgggcg cacccggaag tggacctgga gctgaccgtg gagctgtcgg
     8701 ggacgctcca cgagcggctc gccgaggggc gtctcgatct cgtgctcgcc aagcggcggg
     8761 ccgaggagac gcacggggtg ctggtgtggc gcgacacgct cgtgtgggtc gcgggcgagc
     8821 ggctgcggct cgacccggag cgaccgctcc cgctcatcgt gtacccgccg cccggcatca
     8881 cccgcgatcg ggcgctgcgc gtcctggagc gcgagggccg cgcgtaccgc gtcgcgtgca
     8941 cgagcgggag cctcaacggg ctcgtcgcgg cggcccgcgc gggcctcggg gtcatgccgc
     9001 acgcgcgggg cctgatcccg ccgggcctcg tccgggtgcc cgagcgggcg gggctccccg
     9061 cgctgggcga cgtcgatttc gtcctggtcc acgacgaccg gcgcgcggag gcccgggagc
     9121 cggggcgggc cctcgcggag gcgatcctgg cgagcgggga ccggctgcac ggggggtgag
     9181 aaggggcggg gcgcgcaagg cgaccgggct gggcggacgg agtgaccgga ccggcggagc
     9241 gaccgagccg ggcggaccgg gcggagcgac cggaccgggc ggtacggcga aggggccgcc
     9301 tcgccaagcg gcacgccgac gcggcgcgac ggcctgcggc ggcacggcgg cctgcggcgg
     9361 cgcgacggcc tgcggcgcca cggcggcgcg acggcgaaac ccctttccgg tctcctgacc
     9421 tcgtatgaca tattcccgcc atgcggacag aggtggcggg agacggtacg gggacgagcg
     9481 gcgggcccga cgtcgcggag tgggcgctgc gcgccgccac cgcggcggat ctcgacgccc
     9541 tcgtggagat acgggccgag gtcatgcgcc cggacctgga gcgcctcggg cgctacgacg
     9601 agcaccgcgt gcggcagcgg ctgcgggact ccttctcgcc ggcccacacc tcggcggtcg
     9661 tgtgcggcgg ggcgctcgcg gggtgcgtca ccttccggcc cgccgaggac ggcggccact
     9721 ggctcgaaca cttctacctc gccccccgcc accagggccg gggcctcggc ggcgccgtcc
     9781 tgcgctcgct cctggggcgc gcggacgggc ggcccgtgag cctgcacgtg ctgcgcggca
     9841 gcgccgccca gcggctctac gcccgccacg gcttcgccgt cgaggacgcg ggcccggtcg
     9901 acgtactgat ggtccgaccg gcggacggcg cgaggccgaa ggccgctccc gcgacaccgg
     9961 agacggctcc cacgacgccg ggggccgccc ccgcggcggc tcagggctga acgaggcgga
    10021 cctggtccac ccccatcagc ccggtgagcg gcacccgcgc ggtgcgctgc ccgggatcga
    10081 cgaccaggcc actggaccgg atcatgtcga ggagcatttc ggcgaggggc atgaccatgt
    10141 gccgccccca gcagcgttcg gacgaatgcc cgaagggcag atatccgggg acgcgttcgg
    10201 ggtccagttc ctcccagcgc tccggcctga attcctcggg gttttcccac agcgcgggat
    10261 cgcggtggct gaggaaaggg aggaccagaa cgtcgtcggc gggtgcgatg cgtgcgtcga
    10321 tcacgggata ttcgggcgag gaattgcgca ggatattcca cgaggggggc agcagccgca
    10381 gggactcgtg gacgaggtgg cggctcggca cctcggcggc gaagggggct ccgagccaga
    10441 gggcgttggc gacgagggtg gagatcgtga agcacaccgg cgcggccgtg cgccggtaga
    10501 gccccatcgc gtacctgcgc tcctgatacg tggcggcccc ggtgctcagc gcgccgagcc
    10561 gggtcgtccc ggtacggcgg cgcggtgcgg ggagggcggc tccggcggcg atgacggtcc
    10621 aggtgagctt aggcgtcagc tccagggcgc ggttcatcag gacgcgcagg cggcgcggat
    10681 caccgccgag gatcaggtcc cggaggtaga cgtggccgac gtggggccac gggcccgaga
    10741 ggtcggggtc ccgcggcgcc tcgcgcttga gcgccgcgcg cacgtcgtgg ccgatggcct
    10801 gcatctgcgt cgccgcctgc tggtgcggga tcgcgcggcc gaggagcggt ttgaacgtgg
    10861 gccgttcggt cttgccggcc gggcgcgcgg cgagaatccg gtcgacgagc gcgggccccg
    10921 cgacgccgac cgtgtcgggc tcggggcgga agaggtccgc gccgaggtgg tcgcggagca
    10981 gggcttcgag gggcggcgcg aagagggtct cccgctcgtg ggggcgcgtc tgggtgtgtg
    11041 acgtcatccg tgcagctcca gagaaccggg aaggcggcgc ccggcgaacc cgtcgccggg
    11101 cgccgtcccg gctcgaagat gcgctcccgg gaagagaacg cggccgaggg ggatcagtac
    11161 cagatgtacc aggcgtgagc cttcaggctc ttctgctggg acatcttgtt cttgagcgag
    11221 aaaagcagcc gcattttctt tccttctttc cgggtgggcg gtcgaggaaa accacgcgcc
    11281 ttccggtcga tcgatcggat ttcccgtcgg cgcgctgatg atcagtgaag accagcaatt
    11341 gatggcctgt caacgctcct gggaagaatt tgccacgggc agacctctcc ggcctttttc
    11401 cgggcccggt tgtccgaaag cgagccaccg gggtttatcc ggctcgccgg gcggggagtc
    11461 cgtacggaat cagcgcccgg cgagccgggc cctcctcccc cagggccccg cgcgccgtcc
    11521 cacccccacc tgacaccgtc tcacctgcga aaacacgtgc gacttcggta cagattccgt
    11581 ggaggagggc cgcgcggtac ttactcctca gtcagtaatc ccccgcgatt ctcctcaccg
    11641 cctgtcccgc tgcgccccgg ttggggcggg ttccggggag agatccgggc atatgcgggc
    11701 gggaccggcg ccgcgcgagg gctcccctgg tggcgcttac ctgcggtagc gtctcggcgc
    11761 cgtacccccg caccagcccg gcgcgagggt gcgcggcgcc acgaggagca gctttgcgcg
    11821 agttcagtca gcccccgctg acccgggcgc ggccggtggg cggcctcgcc gactgcgtct
    11881 tcgaccacgc ggtcgaggac ccgggccggg tcgtgctcgc gcgcaagagc ggcgggcgct
    11941 ggcaggacgt gacggcggcc ggtttccgcg atcaggtgct cgcggtcgcg aaggggctgc
    12001 tcgccgaggg catccgcttc ggggaccggg tcgcgctcat ggcgccgacg cgctacgagt
    12061 ggacgctgct cgacttcgcg ctgtggaccg tgggcgcgca ggtggtcccc gtgtacccga
    12121 cgtcgtcggc ggagcaggtg tactggatgc tccacgacgc gcaggccgcc gccgcgttcg
    12181 tggagcacga ggaccacgcg atgacggtcg gctcggtcat cgaccgcctc ccccacctgc
    12241 gccgcctgtg gcagttcgac gcgggcgcgg agcaggagct gatggcggcg ggcgcggaca
    12301 tcgcggacga ggtggtgcac cggcaccgca gggcggtcac gcccgactcg gtggcctcgg
    12361 tcatctacac ctcgggcacg acgggccgcc ccaagggctg cgtcctgacc cacggcaact
    12421 tcatgttcga ggcggacacg ctgctcgacg cgtgggagcc ggtcttcacg ccgcaccacg
    12481 gcgaggaggc gtcgacactg ctgttcctgc cgctcgcgca cgtcttcggg cgcgtcgtgg
    12541 aggtcgccgc ggtacggggg cgggtcaaat tcgggcatca gccccggctc agcgcggacg
    12601 cgctcctccc ggaactggcg gcgttccggc ccagcttcgt cctcgcggtc ccctacatct
    12661 tcgagaagat ctaccgctcg gcggcgcgca gggcggaggc cgaggcgcgc gccggggtct
    12721 tcgcgaaggc ggtcgaggtc gcggtgcggt acgcggaggc gcgcgagcag cgggcgctgg
    12781 ggcggggcgc cgggccgggg gcccagctgc ggatgcagca ccagctctac gacaagctgg
    12841 tgtacgcgcg gctgcgcgcg gtgctcggcg gccgcttgcg gtacgcgatg tcgggcggtt
    12901 cggggatgga ccgcaagctc gggctgttct tctcgggcgc tggcctgacg gtgtacgagg
    12961 ggtacgggct caccgagtcg agcgcggcgg cgacggcgaa cccgccgggc cgggcccgct
    13021 tcggcacggt gggacagccg ctgccgggga cggcggtgcg gatcgcggag gacggcgagg
    13081 tgtggctgcg cggggagcac gtcttccagg gctacctcaa caccccgcgc agcgggcaca
    13141 cggcgctgcg cgagggctgg ctcgcgacgg gcgacatcgg gcggctcgac gaggacggct
    13201 acctcaccat cacgggccgc aagaaggaga tcctcgtgac ctcgggcggc aagagcgtct
    13261 cccccgggcc actggaggac cgggtgcgcg aacacccgct cgtggcgcag tgcgtcgtgc
    13321 tcggcaacga ccgcccgtac gtctcggcgc tcgtcacgct cgacgcggac gcggtctcgc
    13381 actggctgga gatgcgcggg cagccggtcc gcgagccggc ggccgtggtg cgcgatccgg
    13441 agctggagcg ggaggtgcgc cgcgcggtcg tcgcggcgaa cacgcaggtc tcgcaggcgg
    13501 agtcgatccg taccttccgc atcctggcgc gccccttcac cgaggagcag ggcctgctca
    13561 cgccctcgct gaagctcaag cgcaaggcga tcgaggagac gtacgcgcac gagatcacgg
    13621 cgctgtacag gggctgagcc ctccgggcct cccgccgccc cgggaacacg tgcccgcgcg
    13681 cgcgtcgtta aagtcggtga gtacgtccgg cacgggccgg gcggggcgga cggcgcggac
    13741 gccgggccgt ccccgtaccg gcctacgagc gcttaaggat caacagacgc agtgagtgcg
    13801 cacaaggtgg ttcccccgat cgtcctgaac aacggcgtcg agatgccgca gctcggcttc
    13861 ggcgtgtggc aggtgcccga cgaggaggcg acgaccgccg tcgggctcgc gctcgacgcg
    13921 ggctaccgct cgatcgacac agcggcgatc tacggcaacg aacgcggtac gggcaaggcc
    13981 ctcgcggcct cggggctcgc ccgcgaggag ctgttcgtga cgacgaagct gtggaacgag
    14041 gagcaggggt acgactcgac gctgcgggcc ttcgacgcct ccctcgacaa gctcggcctc
    14101 gactacgtgg acctgtacct gatccactgg ccgtgcccgt cgaaggaccg ctacgtcgac
    14161 acgtggcgcg ccttcgagaa gcttctcgcc gacgggcgca cccgcgcgat aggcgtctcc
    14221 aacttcacgc ccgcgcacct ggagcggctc atcggggaga cctcggtgat ccccgcggtc
    14281 aaccagatcg agctgcaccc gcacctgcag cagagcgagt cgcgcgcctt ccacggcgag
    14341 cagggcatcg cgaccgaggc gtggtcgccg ctgggccagg gcaagggcct cctggaggtg
    14401 cccgcgctcg tggcgatcgc ccagaagcac ggccgcaccc cggcgcaggt cgtgctgcgc
    14461 tggcacgtcc agctcggcaa cgtggtcatc cccaagtccg tgactccgtc ccggatcaag
    14521 gagaacatcg acgtgttctc cttcgagctg gacgaggagg acatggccgc gatccacgcc
    14581 ctcaacgagg agcaccggct cggcggccac ccggacgagg tgggctgacc ccgcccgcgc
    14641 gatatgaggg agggaggcgc gcggcgcacg ccgggcgccc ccctccctca tgtcgcgcgc
    14701 gggcgcctca cccccggttc cgcttccgca gggcgagcag ggtgtacgtc gggtccgggc
    14761 gtggctcctc ggggcgcggc agcgcttcga ggcggcgggc caggtcctcg ccgcccgccg
    14821 cgtactggct gccctcgcgc acccgggcgg cgacctcgcg agggctgcgg ccctggccgt
    14881 gcccggtgaa gcgggccgaa ccgtgcgggc gcaggtcgtg cgcggcggcg agcgcggtca
    14941 cgcggcccgc gccgtcgggg agttcgacgg gacggtacgg gtcgagcagc gcgtccatgt
    15001 cgctgccgcg cgcgtgcgcg gccgatttgt cgacagtcgt cacgaagagg ccgccggggc
    15061 gcaggacgcg ggcgacctcg gcgacgaagg gcgcggcgtc gtcgaccaga ttgagcagcc
    15121 acacggcggt gaccgcctcg gcgctgcccg gggcgagcgg cagggcgcgc gcgtcggcgc
    15181 gcacggccgc gtccaggcgt cccgccgcct ggtggagcat cccggcggag aggtccacgc
    15241 cgagcacggt gtacccggcc tcgcgcaggc agccgccgac gatcccggtg ccgcaggcga
    15301 ggtcgacgag ggtgcgcgtg cggcgcggca ggagtcccgc gacggcctcg gcggcggcgc
    15361 gggcgcgcgg gaggccgccc ctgctctcgt cgtagcgggc ggcctcgtcg tcgtagtcga
    15421 gcatgctcag ccccgtaccc cgtgggcggc ggagaggtcc tcgacgcggc gcgcgagggt
    15481 gacgtcgagc gcggtgattc tgccgcccgc gctgtgcgtg tgggtggcca cctcgacggt
    15541 gttgtagccg agggtgaggt cggcgtggtg gtccatgtcc tcctggacgg aggcgatgtg
    15601 gagcacgaga gcggctgcgg cgaggtggtt ggggaggcgg tagaggcggg tgaggcggtc
    15661 gtcctcgctg ctccagccgg gcagggtggc gagggcggtg tcgatctcgg cggcgggcag
    15721 cggacgggcg gcgggcaagg ctgctcctcg gggggggtgc gtccggccgg ggacgggccg
    15781 gttgatggcg gctcaggtta ccggccggtc cgcgcgcgcg gccgggcggg cacgcggggc
    15841 cgccgggtga cgctctttca cgggccgggt caagactttc ttttggtcta ggccaatcca
    15901 ttgacgtgtt cgttacaacg gcgggaaagt gaggcgcctc cacaccccct gggagatccc
    15961 catgagacgt cttcgtgccc tcttgtgcgg cgccgccgcc tccgcgctcg ccgccgccgg
    16021 gctcaccgcg ctgctgcccg cctcggcctc cggcgccgag agcgcgacgc tggacaagcg
    16081 gtggtacgcc gccgcgccct acctcatgcc gctcgacaac gacccgccca gcgccaccgc
    16141 gatcatggac gcctccgggc tcaaggcgtt ccagctcgcc ttcgtcctcg cgccgaacgg
    16201 cggcgggtgc agcccgacgt gggacggcac ggcgccggtc tcctcggaca ccgccgtcgg
    16261 ctccgtcatc agcgcgatcc gcgccaaggg cggcgacgtg tccgtctcga tcggcggcta
    16321 cggcggcacc aagctcggcc agacctgttc cgacgccgcg tcgaccgcgg cggcgtacca
    16381 gcaggtcatc acgaagtacc agctcaaggc catcgacttc gacctggagg agcccgagta
    16441 cgagaacacg gcggcgatcg cccgggagat cggcgcggcg aagatcctgc agaagaacaa
    16501 cccggggctg tacgtctcgg tgacgacggc cggtaccgcg gacggcaccg gctggttcgg
    16561 caagcagatg ctcaacgagg cgaaggccca gggcttcacg cccgacaact tctcgatcat
    16621 gccgttcgac ggcggcttca acggggcggc ctcgcagacc gccgcgctca cggccttcaa
    16681 cggcgtgctg cgctcgacct tcgggtggag cgaggcgacc gcgtacgcgc acgagggctt
    16741 ctcgggcatg aacggccgca gcgacacggg cgagtacttc agccaggccg acttccagac
    16801 ggtcctggac tacacgacca cgcacgggat ggcgcgcttc accttctggt ccctcaaccg
    16861 cgaccggcag tgcagccccg ccgacaacgg cggcaggacc agcggtacgt gcagcagcgt
    16921 gccgcagtcc gcgtgggact tcgccaagtt ctccgtgaag ttcgcgggcg cgaccccgcc
    16981 caccaacccg ccgaccgacc cgaccgaccc gcccaccgac cccggcacgg gccagtgcac
    17041 ggcgggcgcc tggagcgcgg gcgcggtgta cgtcaagggc gacaaggtca cccaggacgg
    17101 gcacacgtgg gaggcgaagt ggtggacgac gaacgagaag cccggcacga cgggcgagtg
    17161 gggcgtgtgg caggacgacg gcccctgctg agcgggacct gaacgggccc ggcggaccgg
    17221 gtacggggcg gggcgggcac acggcgtgtg gccgccccgc ccccgttcgc cgtgcggctg
    17281 gcccgtttcc tcagtgctgg tgatgggcgt ggaccaccgc gtggcccttg ccccgtccga
    17341 tcgtccagcg gttgaccggc gtcgtgacga cgaaggcgag ggcgagcgag cccgcgagcg
    17401 agagccagaa caggacgtcg gcgagacccg cgtccatcgc gcccgggacc gcgaccatcg
    17461 cggtgttgtc gatcagctcc atgaccgcga tcgagaccgt gtcagcggcg agcgcgacct
    17521 tgagggcggc gcgcgggctc agcccggcgc gcaggacacc gcgcatcgtg agcgcgtagc
    17581 cgaagacgaa ggcgaggacg atcgacaggg cgacggtcgc accgttgtgg agtccggcgg
    17641 ccgtcccgat gaccatgccg aggatctctc cgatcgcaca cccggtgagg cagtgcaggg
    17701 tggcctgcgc ggccagggac cagggcgtgc cggaccagcc ggcccggccc tcgtgcgggg
    17761 cgtggtggcc ttcgtggtgc gcgtggtcca tcgtgctccc ccttctcgtg cgtcgtgcct
    17821 cgtgcggagc ggcttccgga ggggagaaca ccataccccc ctggggtatt cccgaggggg
    17881 gtacggcggg cggttcgcgg gtcagcgcct cacggtcacc cgcgcctcag tacgtacgcc
    17941 cgagaccgtc accgccagcg tgaccgtccc cgggcgcagc gccgtgagcc gtcccgtcgc
    18001 cgggtcgtac gcggccgtgt cccgcggccc cgccgtgcgc ggcgggccca cgtgcaggcc
    18061 ccgcgaggcg gaccagtcgg cgctgacggg ccagccgagc gggactgtgc gcgcgccctg
    18121 ggtgaggcgc gcggtgacgg cggcgtcctt gccgggcgcg aggctcgcgg gggcgtcgag
    18181 ccgcagggtg tcggtgtgcg ggcgggtctg gacgccgagc cagccgtccg ggagcgcggc
    18241 gcccggccgt gccgcgcggt cgacgccgag caggctccag ccggtgaagc cgccctcgtc
    18301 ggcgggcgtc gcggggttct tcccggagtt cccgttgacc aggtacggga ccccctcggc
    18361 gtgcgaggcg tcgaaggtgc cgacgtgccc ggcgacgtac gcgacgccct tgccgctcgt
    18421 gcgccggaag tccgcgagcc aggattcgac gagcgcggcc tccttgcggt cgccgagctg
    18481 gctgcccttc tgcggggtcg ggtcgcgcgg cggtacgtgc gcggcgacga cgaccgagtc
    18541 gaccgcgcgg tccttcgccg cggcgtcgag cgcggcgcgc aggcggccga gctgcgcgaa
    18601 gtccgagacg cgcagcccga gcccggaggt gtccagggtc aggaagcggg tgcccttgtg
    18661 gtcgaaggtc tgctccgccg cgccgaactc cttggtgaag ttggcgatcg agccgcccat
    18721 cacctcgtgg ttgccgggga cgtagtgcca gggcacggcg tcgcccagtt cctcgtcgag
    18781 catccggtgg gcgaaggcca ggtcctcggg agagccctcg tcgacgaggt ccccgtcgat
    18841 gagcaggaag tcgggcttcg ccgccttgat ctcgcgcagc gtgcgccgcg cctgcacggc
    18901 gttctcgccg tcggggtccc gcgcgacgaa ctgcgcgtcg gacatgacgg cgaaccgcca
    18961 gtccttgccc cggacgtccc gcgcggtcga gatgagcggg tcgtgggggc gggcgctcgc
    19021 gggcaggtcc accgcgggag gcacctgcgc ggtgaggccg tcgagttcga cctcgccctt
    19081 gtactgcttc gtcgcgtcgg tctcggcgag gtagaagcgg aagacggaga cggggtacgc
    19141 gacggactgc ggcacgggga aggtgacctt cttccacccg gtccagtcca cgtacgggcc
    19201 gcgcagcaac tggtccgtcc cggtcgcgtc cttgaggtgg agcgtcgccc aggcgccgtg
    19261 cccgtctccc ttgagccaca gcgtgaacgc ctgcggctgc ccggtgacgg ggagcggggc
    19321 gggcgggctc gcgtaggcgg cgcgggtcgc ggtcgactgc gtgaagtcgt aggtcatgcg
    19381 cagcccggtg ccgtcgtggc tgtcggggac ggcggcgagc gcaccggcgg cgcgggcctg
    19441 gctgaacgtc cagtcgcccg cgtcgtcgaa gccggtgagg gcctggtccg tgagcccggc
    19501 ggagacggcg agggtcgtgg agtgcccggc gaccgtcgcg gtgacggtgc ccgcggcgcc
    19561 ctccgcgcgc gcccggacgg tgaagccgtc cgcgtcgggg gtgagggtga acagctcgtg
    19621 gtcgtaggtg agccggacgt cggagggctc gacgggggcg ctgttgccct cggcgtcgag
    19681 cccggtgacg ccgaagcggg cgctcgccgt ggcgtcgggg agcgagaggc gccgggtacc
    19741 ggtgtcgacg cggtcgaggg gtccgaggac ggtgagcttc gtggtgccct tcgcgccgcc
    19801 cctgcgggcg gtgatctcgg cggtgccctt cgcgcgcggc gcggtgtagc gcccgtcgcg
    19861 gtcgacggtg cccccgcccc gcaccgtcca cgtgggcgtg ccccgcgcgg gcccgtacgt
    19921 ctcgtcgtgg ccctcggcgg tcaggcggcg gtgcagcccg gggaacacgc ggtcggggtg
    19981 gcccccggcg acggggtcgg cggtcggggc gccgagcggg tccatcgcgg tgctcaccca
    20041 gtagcccgtg aggcggccgg agccgtcggg cgcggtgagg acgaggccgt tggggacggg
    20101 gcgttcggtg ccgtcggagg gctggttgcc gacctggagg gtgtcggtgc cgggggcgcg
    20161 cgtgaggagc gtggcggagc cgccgccgtc gaggttgacg gcgttgtagg cgcccgcctt
    20221 cttcagcatc aggccgagtt cggtgagcgt gacgccgccg ctgtcggcct ggcggccgtc
    20281 gacggtgacg acgtgcaggg tacggccgtc gcggctgaag cccacggcgg tgcggggcgc
    20341 cgcggtgttg ttgccctcgc ccgtgtggtc gacgggcctg ccgtccgtca cgaggtactc
    20401 gttggcgccg atcgcctcgc gcggcggcgc ggagccgtcg cccgtgcgcg ggtggtagct
    20461 ccagctcacg ggcgccccct cgggcagcgc gcgcagcgcc tcggcgccct tgcccgcgcc
    20521 gacgagagcg gtcgccccgg cgggcaggcg tccgctgccc ggccggtgcg cggtgtccgt
    20581 cgtacggccc ccgacgaccg tcacctcggc ggtgtcgcgg gcgctgttga cggtgagggc
    20641 gcggtcggcc tcgccccacg cggccgtgta ggcgccgatg ccgtcggcgg ggacgtcggc
    20701 cgcgttgagc gcggcgagcg ggcggtcgcc cgaggggagg ctcagggtgc cgtcgaagta
    20761 gaggtcgagg acgcggcccg cctgcgcggc atcgaagccg atcgcgcggg tgtgggacgg
    20821 ctgcggcgag ttgaggagcg cgcccgcgtg cagcccggag ccctcggggg cgcccgtctc
    20881 gttgatgtcg aagaagtcac cgttgagcgc ggcgaccgtg cgccgtccct tgcccgggtc
    20941 ctgcccggcg gcgagcgcgg agacgggctc gcgcgcggag acgcccttcg ccgagctgag
    21001 gtactgggcg cgcacggcgg cgccgaggtc ggcggagacc tcgtggacgc gcagccactt
    21061 gtcgctctcc aggcggtcgt acgaggtgag ggaggccccg ggcgcgagcg ggcggcgcgt
    21121 gcgggcggtc tccaggccgt cgccctcggg gtacgcgcgc ggggcgggcg tgtccgtggc
    21181 ggcgagcgtg ctcgcggggg gcggggcggc gggcccggcg gtggcgggcg gggc
//
