LOCUS       BGC0002751             21220 bp    DNA     linear   BCT 22-OCT-2016
DEFINITION  Amycolatopsis xylanica strain CPCC 202699 genome assembly, contig:
            Ga0104457_105, whole genome shotgun sequence.
ACCESSION   BGC0002751
VERSION     BGC0002751
KEYWORDS    WGS.
SOURCE      Amycolatopsis xylanica
  ORGANISM  Amycolatopsis xylanica
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1
  AUTHORS   Varghese,N. and Submissions,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-OCT-2016) DOE - JOINT GENOME INSTITUTE, LBNL, 2800
            Mitchell Drive, Walnut Creek, CA 94598, 94598, USA
COMMENT     ##antiSMASH-Data-START##
            Version     :: 8.dev-5707d64f
            Run date    :: 2025-08-15 22:31:03
            NOTE :: This is a single region extracted from a larger record!
            Orig. start :: 0
            Orig. end   :: 21220
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     region          1..21220
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="atropopeptide"
                     /region_number="1"
                     /rules="atropopeptide_p450"
                     /subregion_numbers="1"
                     /tool="antismash"
     subregion       1..21220
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002751"
                     /subregion_number="1"
                     /tool="antismash"
     cand_cluster    1..21220
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="atropopeptide_p450"
                     /kind="single"
                     /product="atropopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21220
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:11220](-)"
                     /cutoff="10000"
                     /detection_rule="atropopeptide_p450"
                     /neighbourhood="10000"
                     /product="atropopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11220)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="atropopeptide_p450"
                     /neighbourhood="10000"
                     /product="atropopeptide"
                     /protocluster_number="1"
     gene            complement(490..1770)
                     /locus_tag="SAMN05421504_105677"
     gene            1913..3355
                     /locus_tag="SAMN05421504_105678"
     gene            complement(3326..4204)
                     /locus_tag="SAMN05421504_105679"
     gene            4358..5053
                     /locus_tag="SAMN05421504_105680"
     gene            complement(5102..6553)
                     /locus_tag="SAMN05421504_105681"
     gene            complement(6550..8907)
                     /locus_tag="SAMN05421504_105682"
     gene            complement(9033..9983)
                     /locus_tag="SAMN05421504_105683"
     gene            complement(10001..11044)
                     /locus_tag="SAMN05421504_105684"
     CDS             complement(10001..11044)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     atropopeptide: atropopeptide_p450"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic"
                     /locus_tag="SAMN05421504_105684"
                     /product="Cytochrome P450"
                     /protein_id="SDY48146.1"
                     /sec_met_domain="atropopeptide_p450 (E-value: 2.1e-174,
                     bitscore: 566.6, seeds: 287, tool: rule-based-clusters)"
                     /sec_met_domain="p450 (E-value: 3.3e-18, bitscore: 52.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQVSTTGGIARTIVFAPRIDELLRKHRGDGLFRLDHDTVGIGDPH
                     LIDAIMASRPANDFERPTFKPLQGKSISRPESTGLMRAVGQDVRIALKKTDERPVDLSG
                     EWPHVGHVYLRDLIFPGDPMRLLALMDRRLEWTTALTRAVVTAGSALPGWPSPDAPISN
                     LGKIAAEARGYHAKFRAMGLYRRASAPVCFTVSQLVASAIWLGAPFDDQWSNRDIIHET
                     LRLLPVSWNLLRVASPEFPALDARIGPKDDVLMFPLLSHRDPALWDDPDEFRPERWATL
                     DPDHQLGYLPFGHLSERCWGRHMVLPLAERLLDLVREGGYRVDPAQAEAKVPLAGLFGV
                     TKVKVTR"
     misc_feature    complement(10703..10705)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS             complement(11152..11220)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     atropopeptide: atropopeptide_precursor"
                     /gene_kind="biosynthetic"
                     /locus_tag="amyA"
                     /sec_met_domain="atropopeptide_precursor (E-value: 1.0,
                     bitscore: 1.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MKALMRKFKPEKSLKAYAWYIWW"
     gene            complement(11680..12888)
                     /locus_tag="SAMN05421504_105685"
     gene            complement(12885..14108)
                     /locus_tag="SAMN05421504_105686"
     gene            complement(14120..15757)
                     /locus_tag="SAMN05421504_105687"
     gene            complement(15762..17048)
                     /locus_tag="SAMN05421504_105688"
     gene            complement(17125..18090)
                     /locus_tag="SAMN05421504_105689"
     gene            complement(18102..19673)
                     /locus_tag="SAMN05421504_105690"
     gene            complement(19670..20023)
                     /locus_tag="SAMN05421504_105691"
ORIGIN
        1 ggggcgacga cgtggtgctg atcgcgagac gcgggcacgc cgtcgccgcc acgctcgccg
       61 ccgggacgca cctcgtcgaa agacctgaag acgtgaggac gctgcccgcg ttcgatcccg
      121 agcgggtctc gttcctggtc gcgcccggga tgccgatcga agacgccgcg cgggtgctcg
      181 ccgcgctgcg ggcccggttc ccccggctgc gcgggcatca cccggacgaa tggtgttacg
      241 ccgcgtccga tcaacgcgaa accgtgcgct cggtcgcggc ggcgagtgac ctgctgctgc
      301 tctgcgggcc cgtgcacgac gtgcgggggc ggatcctcac cgaggtcggg gagatccggc
      361 cggactggct cgcgcgcgcc gcgaccgtcg ggatcgcggg cgggccgtcc gcgctggtgg
      421 acgcggtgct ccgggcgttg tccgggctcg ggccgctcag cgtcgcccgg cgcaaggtga
      481 ccacggagat cagggcgttc gccgtgcgtt gagcacgagc gccgcgcgct ggccgagcag
      541 ccgcgcggac gggttcttct ggtgcgggcg gacctgggcg cgcagcgtgg cgagcgcggt
      601 gtcggcgcgg cgtgagcgca ggtgcgggta atcgtcgagg aaccggtgcc aggtgtcgca
      661 ggcctggtcg agctgaccgg cggcgagctg gagttcggcc agcctggcga gggtgatcgc
      721 gcgcgagcgc cgctcagcgg ccgggcggtg gaagatcgac gacttcaacg ccctgatcgc
      781 ggcctgccgg tcgccgagcg acgcggccac cgccgcgtgc tggtgcgcca gcgaagcctc
      841 gtggtagccg ccgatcgcga ggtcggcgga ctgcgccgcg gcgagccggt tttcggcgac
      901 gccgagctgg gtgatggcgg cctgccggtc gcctgcggcg gcgcaggcga ccgcgagctg
      961 cccgtgcagg aacgcgcggg tgcgcggaga cgccgtcggc gcggccgccg ccacggccgc
     1021 ttcggcgagg tgcacggcgt tccggtggtg cccgagcgcc cgggcctgca cgctcagcgc
     1081 gcgcaacgcg acggcgtacc ccgtggcgtc ggcggcctgt gcggcgagcc gggcgctggc
     1141 caggtaatag ctctgagccg cgccgtgcag ctcgtcgtcg aaacacatga agccgttgag
     1201 atacgtgagc agggacgcgg aacgcagcag ttcgtgccgg acggccggtg cggcgtcggc
     1261 gcgcagccac ggcgcgatcg tgtacgcgag atagccggcc agcgcggtcc ggccgcggcc
     1321 gccgccgaag gtgacatcgg cgtcggagaa cacctcgatc atcgacgcgg cggaggccgc
     1381 ctcggtccgg ccgacgcgcc cgatcccgtc ccgctgagcg gggaccgcga gctcggccag
     1441 cgagggcacg tcgagctcgg ccaggcggta gatccggtcc ggttcgacca gcagcgacgg
     1501 ggtggcggcc gctccgttgc cggtcatccc ggtcagcgcg accgggatct cgcgccccag
     1561 cctgcgggtg aacgcctccg cgaccaggtc cggcacgggg gagcgcggcc gtgaccccga
     1621 gagccagtgc gcgaccgagg tgcggtcgta actcaggcgc aggcccgctt cgccgccgat
     1681 cgcgttgacc gcggccgcca gcgccccacc ggtccacccc gcctcggtga gcaatgtgcg
     1741 cagcgggtca ttgggccggc gccccgtcat ccattccctt tcggattcaa cagtgtgccg
     1801 atgttcaaca catccgggcc gatggaccag accaccggcg ggttccggcg ggctaactag
     1861 aaggatgacg gaccgttggt gcgacgagca ttacccgatc gggtggtaga aaatggcact
     1921 cagcgaagta ctcgacgaac ggcacgcgac cggcctgcga ggactgtcca gatcggcctt
     1981 gagacgcctc gccgcggact tgcgtggcga acgggtggat tcgacgatgg tcgagctcac
     2041 cctcgcgctg caccgggttt tcgactccag ccgtgacgta ctgctcttcg acacggccga
     2101 gcaggcgtcc gtccaccgga tgctcatcga ctcgcgcgac ggcctgccgg ggcattccac
     2161 cgcgctctcg tacgcggacg gcctcgccaa ggcgttcgca ctgcgcggcc accgcgaccg
     2221 gcgcgtggtc gcggtcgtca gcgacgcctc gctgaccggc ggcatgtgct gggaggcgct
     2281 caacaacatc ggcggtgccc ctgaccgccg cgtgatcatc gtgctcaacg acagcggcac
     2341 gagctacgac ccgaccgacg gcggcatcgt gcaccacctc gcccggctgc ggcggctgcg
     2401 cgggcgcaac gtcttcgccc agctcgggct cgcctacatc ggcccggtcg acggccacga
     2461 cctcggcgcg gtcgaacact gcctcgagcg cgcgaaacgc tcgtgccgcc cggtggtcgt
     2521 gcacttcaag acccccgacg gcgccgagcg gcccgtacgc ccgtgggcgt cggcgttcga
     2581 cgaggagctg accgagatcg gcgccgagcg ccgcgaggtc gtctgcgtga ccaccggccc
     2641 ggtcgactca ctcacccgct tcacgcatcg cttcccggcc cgggtcttcg gcgccgggat
     2701 ggccgagcag cacgccgtca cctccgccgc cgggctcgcg ctcggtggcc tgcggccggt
     2761 ggtgaccgtg cccgcgtccc tgctcggccg ggcgttcgac caggtcgtca ccgacgtcgc
     2821 gcagcgcggg ctcgccgtga ccttcgtgct cgacggcgcg gccgacacgg cgatactgcc
     2881 gatggtgccc tcactcggcc tcgccgtgcc gcgcgaccgc gcccgcctgc ggtccctgct
     2941 gcgcgaggcc atcgcggtca gcagcgggcc gacggtactc cgctgccccg acacgaccgc
     3001 cgacgtgccc gcggtgcgtt cgctcggccg ctgcgacctc ctccgctcgg acctcggtgc
     3061 gcgcgtgctc ctgctgccga tcggcaccgc cgccccggcc tgcctcgccg ccgccgacga
     3121 cctcgccggg cgcggcgtgc gggtcaccgt cgccgatccg cgctgggtct ccccgcccga
     3181 tccggcgctg ctcacgctgg cgggcgcgca cgacctcgtg gtcgtgacgg gccagccggt
     3241 ggaggccggt tcgctggcgg cgtcgctcgc gcatccgaac gccgtcgtca ccggcgccgc
     3301 cgggatcacc gccgccgtgc tcggctcact tgccggggga gacgatcacg ggtgagccct
     3361 gcggcaccgg gagcacctgc accttgcccg ccttgatcgc ttcgttgacc gcctgctgct
     3421 gctggtagga ctggtagccg ggaatgccgc ccgggaagct cgccgccgcc tgcttgtcga
     3481 cctcggccgc ctgctgccgc agttcggcgg cctgcttgtc ggtgaggccc tgcaccagtg
     3541 cgggctggat gccgggcttc tgcagcagaa ccgagttgat ggtgatcagg tcgacaccct
     3601 gggtcagcga cttgagcacg gcgggcagct gctcgaggac gtcgtgttcc cactgggctt
     3661 tcgcggcggc gtcggtgtac agcttctgcc aggggtactt gagcgcctcg ttgtcggtcg
     3721 cccggtccag cgccgcaccg acgtaattgc gcagcagcga tttccagccc tccttcatgg
     3781 gctggccgcc gtcggtcggc gccgcgtcgt acttgtaggc gatgagctcg tggaacatct
     3841 gcagcttgcc gcctggccat ttcttgccgc tcgggtcggt gaactcgtgg cagtcggtgt
     3901 tgagggtgaa cttcaccgtg ccggtcacct tcacctcctg ggagtcctgg gtggtggagg
     3961 tcagcgcggc cgagtccatt ccgtcaccgt cgccgaacga gaagtcacgc tggccggtcg
     4021 ggtagtagta gtggtcgtcg ttgacgtcgc tcacgtcgcg gtcggtctcg cattcgacga
     4081 aattgcgcga gtcgaacggc ccgccgccgt actgcagcga gacctcgctc gaattgggat
     4141 tcccgatcga gcacccggcg agcgaaagcg cgaagaacgg caggacgagc tggcggatct
     4201 tcatcgttgt tccccctgga tgacgcggag gcggcaccgt cgcgccccac tgccacgatt
     4261 gcagcacacc aggtgagcag gggtaccgcc gaaggtcagc acctcgtgcc ttaaagtcat
     4321 ggccaggggt ttcacatcat ttccaggggg attcgtcatg cctgcacacc tgaagagacc
     4381 gcacgtcctc gtgctggccg tgctcgcctt cgccgtcgcg ggctgcacgg ccgtcaccgg
     4441 ccacgggagc agggaaggcg gcgtcacgac caccgggccg aacgccgcct cggccaccag
     4501 caccgcgccg acgaccaccg agcggccgta catgacggtc acgccgacgc tggagatcac
     4561 cggtgaggcg gcgaagcccg gcaccaaggt gaagttcggc gagcaggctg tgctgccggt
     4621 ctacagctac tacgccaagg gccagctcgg cgtcacgctc accgtcgaga cggtcaaggc
     4681 gtccgatgag gacgtcgaag gcctgccgct caaggacgag gacaagacca agctgcgcgg
     4741 gaagttcttc ttcttcgtga agcagacact ggtcaatgtg gacggtgcga acctctcgga
     4801 gctctacgtg cccacgttca ccccgacgac caggagcggc ggctggccag gccagctgtt
     4861 cgggatgggg aacacgagcg tcaccggctg cgaggacgtc acgtcgctgc cgaaggactt
     4921 caccgccaag ggcgcgaagt tcgaggcctg caagctctac ttcggagtgt cgtccgaccc
     4981 gatcgcctcg gtcgcctaca ccaaggcgcc gtacgacacg ggcgccacga aggccgtcac
     5041 ctggaagaag tgaccgtcct ttgaggtcac cccggccgga gtgacctcaa aggacggacg
     5101 gctacggcgt gaccggcgcg ttggtcaggc ctttcaccgc acgggtgacg gtgttcgacg
     5161 cgtacacgac gttcggctgc tccttgcact gtgacaccga agtgatcttg atggcgtact
     5221 cgccgacgcc gccgaggtcg gacttgttgt cgcgccagac gttcccgcag ccgttggggt
     5281 aggcgggagt ggtgcccggg ttgtgcgtct cgtagccgtt ggcgaacttg cccggcgtgg
     5341 tgaacgtgcc ggtgttgcct tcgatcgtgt acccgatgcc cttgacgtcg acccaggaat
     5401 cggccgagtt ctcgccggtg acgccctggc cgtcgaaggt gttgccccgg atgaggccgt
     5461 tgaatgtgcc ttccttgacg tcgatcgcct cggccgcgat gtacgggccg aagtggttgc
     5521 cgatcacctg gatccggtcg cccttgtcga cgccgccgga gttgccgtgg cagccccagt
     5581 tcgagcccgc cgagccgagg tacacaccct cgccgtagcc cggctgcacc agaccggtgt
     5641 agctgatctt ggagttgcgg atcaggctgt ccgaagagga cttgcggaag tgcacggcct
     5701 cctcgtcgac gtggtcgacc gtcacgccgt cgatcacggt gtgcggcgag ttgtcggcga
     5761 cgatgccctt tttggactct cgcacggtga agccgctgag gttccagtac ggggcgttgt
     5821 acagccagag cccgtacccg gagtcccagc ccgccgtcgg cgccgggcac tcgggtgggt
     5881 cgccagccgg gccgtcgttg atcaggatcg cgccggagcc ggtcagggag atcggcttcg
     5941 ccgcggtgcc agcccggctg gtctggaagg aaccgtgata ggtgcccgcc gcgagcttga
     6001 tcgtctgccc cgggttcacc gccgcgagcg ccgcttgcag ctgcgccgtc gtggagacgt
     6061 tgatcgtgtc gccgggactg gggctgctgg tggtcgtcgg ggtggtcgtc gtcgtgctcg
     6121 ttgtcgtcgt gctggtcggg gtggtgggtg tcgtcgtcgg cgtgccgccg ccgcacggcg
     6181 cgccgttgac cgagcagccg ctcggcaggc cgagcccggc ggcgttgaag ccgaacccgg
     6241 tggtgccacc gggtttgatc ttcccgttgg tcgaggtgtt cgtgaacttg tagtgctgcc
     6301 cggtcttggt catgaccgag ctccacgagt tgctgaccgt ggtgccggac ggcaggtcga
     6361 actcgaccgt ccacgaggtg ctcgccgtgt caccggtgtt ggccagcgcg aaccggccgc
     6421 cgtatccgct gtcccacacc gaactctggg tgaacgtcgc cgacacgctc ggcgccgctt
     6481 cggccgtcac cacgacgccg aggcccgccg cggtgaccgc ggccgcgctc accgcccata
     6541 gccgcttcct catgaggtgc ctccgcaggg ggttccggcg agcgcgcagt tggacggcag
     6601 gccgcgcccg gcggcgttga agccgaacgt ggtggtgcca ccgggtttga tcttgccgtt
     6661 ggtcgaggtg ttcgtgaact tgtagtgctg cccggtcttg gtcagcaccg agctccacga
     6721 gttgctgacc gtggtgcccg aaggcaggtc gaactcgacc gcccaggacg tggtcgcggt
     6781 ggcgcaggtg ttggcgatgg tgaaggagcc gccgtacccg ctgtcccaca ccgacttctg
     6841 ggtgaacgtc gccttcacac agcccgatgg cggctggctg gtcgtcgtgg tcggactcgt
     6901 cggggtcgtg ggtgtcgtgg tggtgctcgt cggggttgtc gtggtgctgg tcggggtcgt
     6961 gctggtcggt ggctgggtgc cgtcgacaga cttcaggaac agcgaggccg ccgcgtcggt
     7021 cttggtggcg tcgacgccgt ggccgccggt gtagtccttc tgctcgttct tcgcccagtc
     7081 ggcgatcggg gtgccgccga tgtcgaggtg cttgaacgcg gcgccgtccc agccgaactg
     7141 gtacacgcgg tggtgatcgg cgtagaagtc gccgaacgcg ccgccctcgg cgagctgctt
     7201 ggtcatggtg ttgttgaaga agacgttgcg cgggccggac gaccccgacc acttgatcgc
     7261 cttctgcccg gcggcccacc agatcgggaa ccagttggag tcgtcgggcc cgccgccgcc
     7321 ctcttcaccg cagttcgccc ggcagttgcc ggaccggtgc gcgtagggga ccttgacggt
     7381 gttgagctcg aacaggttgt tgcgttcgta gccgccgtgc aggttgaggt cggagtcgaa
     7441 ggagttgccg atcaccacgt tgcccgaggc gccccactgg aaggtgaagt gccgcaacag
     7501 ggtcgaggtg ttgcccgcgt agagcgagtc ccacacccgc gagccgcgga agtagccgtt
     7561 gccgcccttg cccttgttcc acgaaccgtt gagctcgttg ttcacgatct gcaggttctt
     7621 ggcctcttcg gtgacgatcg ggtgcgagcc ggtcatgtcc gtgcgtacgc cgcggaccca
     7681 ggaattggcc gcccacttga acacgatgcc gtgcatctcg gcggcgggcg ccatgttgcc
     7741 gtagttgtgc gtggcctcgg cggggtccag gcccggcatc tcctgggtga agccgagatc
     7801 ctcgaagccg acgccgagca ccgggtcgac cagcggggcg gccttggagt cgtaggcagc
     7861 gccgtcgatc ggggccgaac cgtccgaaat ggacgtcacg gggacgtcgt actccagcgg
     7921 cttgtccaag gtgatcgtgc gcgccgaggt gtcgagcgcg gcgatggtga agatctgctg
     7981 gcgcatgtgc atgttcagca gcggatacgc cgttccggtc gcgttctgct gctggtagaa
     8041 cttggtgctg ttggccgcgc ggatgttcac caggttgccc gcggcgaggt tggtcagcgc
     8101 gccgctgctc gccagataga cgaccttgtc gccggtcttg gcggcgtagg cggtgtcacc
     8161 cggcttgccg cgcagcttga ggcccgcctt ccagtgcacg ttgaccgtgc cctcgaagat
     8221 gtccttgcgg ttggcgggcg ccgcggcgta gtcgctcgcg taggacgggt cgacgccccg
     8281 tgactgcacc cggaacaggc cgcggcccgg ccacagccag ccgcccttgc cggcgcccga
     8341 ggtcatcccg tcctcgtccc agtcggaccc gtcgggggtg agcgcgtcgt agagcgtgtt
     8401 cgcgtcgggc ttgtagacga acttggtcgc gtccttgccc gcgccgcgca ggatcagata
     8461 gtcggcgtcc acatgcaact cgtgggacac gtccagcctg ccggccggga agttgatcag
     8521 gctgagcttc gagtagctcg cgctggggga gcaggccgac ttgatcgcgt cgatcgcggc
     8581 ctggatgccg ttggtgtcgt cgacaccgtc atctggtctg acgttgtact ggcccgccag
     8641 ctcggccggg gtgatctgac aggcagcgct ggggttgacc tcgttggcgc cgggtagcgc
     8701 ggaacccccg cggaaaccgg ctttactcca gtcgtagagc ccggcgaccg gcgcgcggcg
     8761 attggcggaa ccgaggtcca ggccggtgag cgcgcctggt cctggcgccg cctcggctgg
     8821 ttccttgacc acttcgacgg cggccaccgc ggccagaatc gtgagcgata ccaacaaaag
     8881 ggcatgacga ggggttttcc gggacacccg aaacctccgg tacagcaatg gcggaaaggt
     8941 gttgcggcgt gtacacctgg accctgtctt tataggtcac catgctggcg tgcgtcaacg
     9001 aatgtgaatg gcgtccatat atgtgaacaa acctaggcgg gattacgcct cggtttgagc
     9061 cgtccgcccg gcaacttcgg ggcgggcaaa cgatcacccg gatagccgtc gacacggccg
     9121 aaacgagctg acccggcttc ccattcctcg cggaaccgcg cgatctcgtc atgatcgcgg
     9181 ccgacgaagt tccaccacat gaccagctct tcggcgaacg gctcaccgcc gagcacgatc
     9241 acccggctcg tttcgtcgcc aggattggca aggtaaaggg aattcgcccc gatgcccgcg
     9301 tagccgagtt cggcgtgcgc gagcggtgtg ccttcgagtt cgacggcgcc ggcgtcaacg
     9361 agaacaccgt gttcgaacgc cgggtcgacc tcgagcgcca gcttcgcgcc tggctccagc
     9421 acgagttccg cgcccagcaa cggcgtgaag gtcggcacgg gagaagtggc cccggcaagc
     9481 gatccgagaa aaacgcgcgc ggtcgccccc gccaactcga ccggttcagg gacgaaatgc
     9541 tgaaagtcgc gaggcgcgtc ccggtgcgcg tccggcagcg cgacccacag ttgcacgccg
     9601 tgcaacgtcg tgctcgcgtc ggtcgacacc tcggagtggc agatcccgtg cccgccggtc
     9661 atcaggttca gctcacccgg ccgcaccatc gcgtgcacac ccaggctgtc gcgatgctcg
     9721 atctcgccgg tgaacagcca gctcaccgtc tgcaacccgg tatgcggatg cggcgcgaca
     9781 tccatccgcg cgtcctcggg cccgtaatgg tcggcgaagc accacgcgcc gatgagcgac
     9841 cggtcgcgct gcggcagcgt ccgccggacc tgcatcgccc gcgggccccc gagcggcacg
     9901 tcgcgcgggg tgagcacctc gacggcccgc cccggctcgc tgcggcaggt caactcggcg
     9961 gggctggttt cgacgttgct cacccgccga tcataaggcc ctacctggtc actttcactt
    10021 tggtgacacc gaacagcccc gcgagcggga ccttcgcttc ggcttgcgcc gggtcgacgc
    10081 ggtagccgcc ctcgcggacc aggtcgagca ggcgctcggc cagcggcagc accatgtggc
    10141 ggccccagca gcgttcgctg aggtggccga acggcaagta gccgagctgg tggtcggggt
    10201 cgagcgtggc ccagcgctcc ggccggaact cgtcggggtc gtcccagagc gcggggtcgc
    10261 ggtggctgag caacgggaac atcaggacgt cgtccttcgg cccgatccgg gcgtcgagcg
    10321 cggggaattc cggtgacgcg acccgcagca ggttccacga gacgggcagc agccgcagcg
    10381 tctcgtggat gatgtcgcgg ttcgaccact ggtcgtcgaa gggggcgccg agccagatcg
    10441 cgctcgcgac cagctgcgaa accgtgaagc acacgggagc ggaagcgcgc cgatagagcc
    10501 ccatggcgcg aaacttggcg tggtagcccc gcgcctcggc ggcgatcttc cccaggttcg
    10561 agatcggcgc gtccggcgag ggccatccgg gcagtgccga gcccgcggtc acgacggccc
    10621 tggtcagcgc ggtggtccat tccagccgcc gatccatcag cgcgagcagt cgcatcggat
    10681 cgccgggaaa gatgagatca cgtaaataga catgtccgac atgcggccat tccccggaca
    10741 ggtcgaccgg ccgttcgtcg gttttcttca aggcgatccg cacatcctgc ccgaccgccc
    10801 gcatgagccc ggtcgattcc ggccggctga tcgatttgcc ctgcagcggc ttgaacgtcg
    10861 gccgctcgaa atcattggca ggcctgctgg ccatgatcgc gtcgatcagg tgcggatcgc
    10921 cgatccccac cgtgtcgtga tccagccgga aaagaccatc gccgcgatgt tttcgcagca
    10981 attcgtcaat tctcggtgcg aagacgatgg tgcgggcgat gccgcccgtg gtggaaacct
    11041 gcatttcagg gcactcccag ccgtgaccgg accccaggtc ggcggcggcc tcgcgggagg
    11101 tcgccgccga cctggggttt cttaaggaat taccaggtca gcgcctgttc accaccagat
    11161 gtaccaagcg taggccttga ggctcttctc gggcttgaac ttccgcatga gtgccttcat
    11221 agcaatacct ccgggtgtat ctggatgttt ttcaaggtca ggcgactccg ggacggtgga
    11281 tcacaccaat gcgagtgaag caattgcatt ccccccgaat ttgcgccttg aaaaaagtca
    11341 atcccagccc gagttgaacg tcaatgtgac gtagctcact tatcaataaa atagattcca
    11401 tgtatttggc gaactcaccc gatgttccgc tgaaagagat tgctgacaac ttcctgacat
    11461 attccttact gaatttccac cgggtgatga tttgtcaaga tgcttgcgcg agtggtacct
    11521 ctgctccgtt agatgcagcg gagttcccac tcgcgcgggc acggtctcct gattcgagct
    11581 gcgttattcg acctgcccgt cgcgctccga cgtccgttac gggtggtcgt gagtgttccg
    11641 gccggttcta accggcctaa acactcacga ccccaacggc taggcgggta cgggctcggg
    11701 ggtgaccggg gtccggttga gcagcacccg gaactgggcg atcaccacga gcccggccac
    11761 gccgtacagg agcgcgatgc cccacggcgg gaccagggcg cccagggtga tgcagccggc
    11821 cgcgagcatc tgggcgaccc ggatgttcag gttgtacacc gccatatagc gggtacgggc
    11881 ctggtccggg accatgttcg ccagcatcgc ctgcttgacc gggacgttca tcagctcgcc
    11941 gaccgtgaac accgcgcccg cgatcagcag cacccagccc gtgttcgaca ccgccagcac
    12001 catgtacccg gccgtgaaca gcccgacgcc cgcgaacagc cggaacctgt ccgagagccg
    12061 ccggaacagc aggtgcgaga acagcgcgag caccacgacc aaggccgtgt tctccgcgcg
    12121 caggacgccc aagatctcga cgccattggg catgtcgtgc gccagccgga caccgacgta
    12181 gttgaccagc tggaactcga tcgccatgat cagcgtcgcc gcgaccatga accggatgaa
    12241 catcccgtca cgcagcacga gccgatagcc tgccgagaac tcacgcagga ccgaagcgcg
    12301 cggcgcggcc gggtcaccgt ccggtttgga ctccgcgatg aggaagtacg tcaccgcgaa
    12361 cacgcccgcc gtgcacgcgg ccgcgccgcc gagcagcagc gtgaagtgtc cattgtagag
    12421 gaatccgccg agcaggccgc cgatggcgag cgcgaggttc gtcgcccagt agttcatcgt
    12481 gtagacctgc ttgcggtcct ccggcgtggt gacgtcgacg atcatcgcgt cgttcgcggg
    12541 cagcgcgagg ctggccgcga acttgttgac caaatagccc gcgtacacca gcagggtcac
    12601 gttcgacgcg tcggcgacgg ccatcaccgc gaagctggcg aagccgccga attcggccag
    12661 cagcaaggtg ttgcggcggc cacgggtgtc ggagatgtgg ccgccgacga gcatgccgat
    12721 cacgccgagc gagacgaccg cgaacatcag cacgcccgcc accgcgatgc cgaagcggaa
    12781 cgccagatag atcgccatga acgaggtgat catcgagtcg agcagccggt tgacgaaccc
    12841 gacgccgatg cggatccgca acgtcggatg caggctcagg aagttcattc cgtcaccacc
    12901 gtcacgagtg acttgatcag ttcgagtcgc gtctcggtct cggcttcgtc ctttccggac
    12961 aacgtgacgt agccgtggcg cgtcttcgag tcgaccgtct ccgggatgac gtcgcccggc
    13021 gagaacggga agctcagttc ggccacgaaa tccaggtcgc ggaccgcgtc gagaccgtcg
    13081 accgaccgca gaacgccggg cttgaaggag aagtagtgca cgcgggccac gtccgaccgg
    13141 gtcttcgggt ccagtgcctc gcccttcaac gccctgaaga tggcgcgctc gatgtcgaag
    13201 ccggtggcca tctccacgag ctggggaatg cggtcaccgc cgagccgcgc ctgcgattcg
    13261 acgattttcg ggccgcgctt ggtccagatg acctcggtgt gggcggggcc gttctggtag
    13321 ccggtgacgc gcagcaggtg cctggtcagc gtggcgatcg ccttggtctg ggacgactcg
    13381 gcgaccgggt ggacgtgacc agcctcgacc accgacggcg gcgggccgag tatcttgcgg
    13441 gtgatgccga tgatgtggtg ctcaccgcgc accgagatgc tctcgacgct gaactcgggt
    13501 ccgtcgagga actcctcgat cagcaccggg ccggtgtagt cgtaggactc cagcagcctg
    13561 ccccagtccg cgagctgcgc gcggtcggtc agcttgagca cgccccggct gcccgccagg
    13621 tccgtcggct tgacgatggc gggcaggcgg aagtcgccga tcatcgactc gacgtcctgc
    13681 cagcgctggg cgtaggcgta ctggacgctg gaaagtccat gcgcggtaag gagtttccgc
    13741 atctcggcct tgtcgttgag caggcggatc gagcgcggcg ggttgaccgc cttgcccagc
    13801 tcgtccgcga tctcgtacgc ggcgagcatg ctggtctcct ggccgacgtg gtagatctgc
    13861 tgggcgccgg agttcgccgc ggccttctcg atggtctcgg cgaactcctc cgcgtccgtg
    13921 aagtcggcga ggatgaagtc ttcggcgagg ccttcgactt ctttgaggta ggcggggaaa
    13981 ccggcaggcc cggtcggcat gaccgaggcc agcgaggggt cccagatggc actgacggcg
    14041 aacccctctt gcgtggcctt cttcacgaaa gccttgtagg gcatcaccat cacaagtggg
    14101 gtgaccatga tcgtctcctt tagacggtag cgaagcggcg tgggtcggcg gaataggttt
    14161 cgagtgcgtc gtacttctgg cggagctgtc gcttgaggac tttcccggtg acaccgaccg
    14221 gcacgcctgc gtcgctgatc tccagcacgc cgagccgcgg atgccccgcg gcgtcgagtg
    14281 cctcgttcgc gagcaggagc agcttctcgg cttcgacgac cacgtcatcg ccgatgctca
    14341 ccagcgccac cggggtgacg gcgccgtcgt gcttgcccgc cacgaccgag gcgtccacga
    14401 cctcgggcac gccggagagg atggcctcct ccatcgacac cgagtagccg acaccgtgtg
    14461 gcgtctcgat cacgtcggcg gagcggtcga ccaggaagtg gtcgccgttc tcgtcgcggt
    14521 aggcgttgtc gccggtgagc cagtacccgg cgaggcggct gctgtaggtg atgtcggcgt
    14581 tggcccagta gcccggggtg atcgccgggc cgcgtgcgcc gagcaggccg atctcgttgt
    14641 cggccgcgat cgtgccgtcg gcgcgcagca cgaccacctc ggcgacaccg accggtttgc
    14701 ccgcgcagcg gtcgttgcgt gcggtgctca ggttgcggat cttgagcagt acgccccagc
    14761 cgagctcggt ggtgcccagc cggtcgagaa acaccgacgg cggcttgtgt ggactgcgca
    14821 aaccgaggat gtgcttgata tgcgtctcgt gcacggcgtc cccaatggac acccagacgt
    14881 tcactgagtc gaccgaaccc ggtttgatct ccagcccggg aatctcggcg taggcgtgcg
    14941 cgaacgacat caccgcgctc ggcttctgct ggacgacgca gtcgacgagt tccgcggcgc
    15001 agcggtcgaa cgcggccacc gtgttggcgc ccgccagcac cgcgtacgcc gtgtacgcga
    15061 tacagccgag atgtgactgg gggagcgagg tcatggtgac cgcacccggg aactccttgt
    15121 ggtcgaccag ccggaacttc ggaccagcca caatggactg atgcgtgtgg acggtcggct
    15181 tcggctcgcc ggtcgtgccc gacgagtgca ggatgaccac cggatcctcg ttcttgtgtt
    15241 ggaacctggc ctcggacggc agatcggcgg ccgggggagc gggcagcgcc tcggccgtga
    15301 cgatccagtt cagctccggc agatcgacga gccgcgactc ggtcgtgtac agcccgaccg
    15361 gcgtggtctg ctcgatcagc gaccgcgcga tgtccgccgg cgcgttgctg ttgatcagca
    15421 ccgcgatcgc gccgatctgc gcgagcgcgt agaagtgcac cgagtacgcg aacgagtcgt
    15481 cgaggtagac ggcgacgcga tcgcgcggca ccacgccctg tgcgaggtac caggccgacc
    15541 agttctgcac cagccagtcg agcttgagca ggctgaactc gcaggtctcc cagccggggc
    15601 tgagcgggat cgggcgttcc gtgcgcagga acggcagctc cggatgcggg ctgtaggcga
    15661 tcgccgaccg cagcaggttg ccgccgccga cggccgggtc ggcggcgagt tcggcccgcc
    15721 gccgcggcga cagggtggtc tcactcgaga gtgccatcgg actacctttc cgacacgacg
    15781 tggacggtga cctcaccggc gaaccactcg gcgagcggct cggccgggct gccgaacggg
    15841 acgtcgaaca gcaccgaacc ggagcgctgc tcgccgtcgg tctgcgcccc cagcacggct
    15901 ccgggctgct gggtgacgaa cacggcacgg gctccggcgg gtgcgttcgc ggccacgggc
    15961 gccatcgcgg ggtaccggtc gtcccgctcc acccaggaaa ccggggcgct ggtgctggtc
    16021 acgtcgacca gcacaccgtg cgggtgatcc agatagacct gccgggcgcg acggcgcggc
    16081 gcggggtagt cggcgggctg gccgagcgcg aggtccagca tcaccggctc cagcggctcg
    16141 cccgtcgcca ggtgccacag gaacgtgatc ccgccgccgg gcacccggac cgcgacctcc
    16201 atcagcaccg cgcggccctc ggagatgcgg aactccgcgt gcgcgatccc gtcgcggaag
    16261 tccaagcgcc gcaacacttc cgcgttcgcg gcgaacagca ggtcctcgtc gctcacggcc
    16321 agctcggccg ggcaggtgtg gcccatctcg gtgaagaacg accccgagga ctcgttggtc
    16381 tccttggccg tgaccgcgtt ccagaacacc ttgccgtgct gcaccagcga ttcgaccgag
    16441 aactccgggc cgacgacccg gctctcgatc agcacgatct cgtcggccgg atagcctgcg
    16501 agaacctcgg cgagccgctc gccgtcgtcg acctggtaga cgcccaggct ggagaaccgg
    16561 ccgatcggct tgaccaccac cgggaagctg atctccgccg ggtcgacgtc cgcgcgctcg
    16621 gcgggcgtga ccacccgcca gtccggcgag tactcgggta aagccgtgcg ctgcaacagc
    16681 ttgttccgcg agatccggct cgcgcccgag cccgcgcccg gcagcccgag cacgtccgcg
    16741 accaccccgg tcggctcgac gaacaggtcg ccgatgcaca tggtgccctg gacgtcgtag
    16801 cgccgcagca gcggctggat acccggcatg accgcgtcga cggtcgcgtc cgggacctcg
    16861 acgacgtcgg ccagctggga cagtggatgg ctcggatccg cgcgtaactc ggcgagccgc
    16921 gcggggtcgg tgtgcggggt gaccacgagc agcggcgcgt agccacggcg ccgtgcctcg
    16981 gtgatgagcc tggcctgccg cgcgacgatc acgaggtcgc cgaggaacag gaaagcgggt
    17041 gcgcgcatgg gaaatccctc cagaaacgac gaacgcccca cccgggattc ccggatgggg
    17101 cgttcttggt tgtatgcggt tgtgtcagcg aatgaggacg tacccgtcac cgggccggtg
    17161 atcccgcgac cgccggacgt cggcggccac gaacgtgcgt tgcagccagc gatccgtgcc
    17221 gtcgtagcgt ggccggaagg cggtgcgccc gtgcaccgtc acccggttgt ccacaatggc
    17281 cagatcaccc ggctccagct tggtgaccga ggcgccggac gcgaacgcct cgccgagctc
    17341 ggcgagcgcc gcggcggcgc gcggggtcag cggggtcgtc gccgcgaggt cgacccgcat
    17401 gtccgggtcg tcctccgcgc cgaagagcac cgcgtgcggc gcggtcgcgc cgtcacttcc
    17461 cccgaacgac ggcggtggct ccgtcacgaa ctcctcgtgg aacaaggctt cccgcgtttc
    17521 cgtgctgagc agcggcagga cctcgcggat gcacgctgtg cgcagcccgg cgacccggtc
    17581 ggggtcggcg cgcaggcaca gcagcatcac gaagtccggc cggtgctcgt ggaacgcgtt
    17641 ctcgttgtgg aacgagagca gcaccgagcc cgagttgccc tgcatctcct cctgccctgg
    17701 caccggcacc acgttctgca ccagcgcgcc cgacttctcg gccttgaacg cggccgggtc
    17761 gccgagcccg caggcgacca gcaccagcga agccgccgag accgtcgccg agcgctcgac
    17821 cgagccgagc accgacggcg tcacgccagg ctcaccgatc ggcaccccgc gcacgagcag
    17881 cgcgccgcgc ggcccggaat gcctgcggaa ctcccgcagc gaccggcgca gcgccagcgg
    17941 cagcagatcc cagccgctcc tggcctgcgc gacccagccg gggtcgtcga cctcgcccga
    18001 actcagcgcg cgggtcacct gctcgaactc ggccgtgtcg cccggtctga ggatgacctc
    18061 ggacgtgggc gcgtgtgtga ccactgacat ctgtgaatcc cctagtcacc tatgagtgga
    18121 acgtcgaacg gggccaccgc gtacagcacg ggcgcttcca tctggagagc gaagccaccc
    18181 gcctcggcca cggcggcggc gaggtcgatc aggatcggcg atgcgccgct gatcagcgcg
    18241 cggacctcgt agaacaggtc accgagctgg tccggccgca gtgcctcgcg gttgagccgg
    18301 tcgagctgcg cgacgatcag gtccgccgcc ctggtcaggc tgtagccgga aagctcgtag
    18361 cagatccgga atcgcgagag caccgcttcc gcgcgttgcc gggcgtcggc ggagaccggc
    18421 agttcacgtc cctcgacacc cgactgtatg cctaaatcag cgaccgcctt ggcgagctgg
    18481 ttcgccagcc ggttccacgg ctcggcgagc cgccgcccgg cgaccttgtc gaggccctcg
    18541 cggctgaagt tggtgcgctg gtgctccggg cagctgaccg cgagatagaa ccggatcagg
    18601 tccctcggca cctctcggag caggtccttc gtgtacagca cgtgcccgag gctggtcgag
    18661 aacttgtcgt tctccagctc gtagaactcg ttggagatga tcgtgtccgg caccacgtac
    18721 ttgccctcgt gcgccaggat cagcgccagg tgcgtgaggc cccagaagta cacgttgtcg
    18781 aagccgatga agtagatgac ctcggcgtcg tgctccgcgc gccacagctc gtgatcgtct
    18841 tcgtgcttct cgccgagctg ctcggcggcg tacgcggtgc agtacatcac cgccgggatc
    18901 ccctcgaccc aggcgttgag cacctggcct tcggtctccg ggaacggcgc cgggatgccc
    18961 cacgagatcg ggtacgtgat cgggaagtcc ggcaacggct tcgcgagcag ctcgtcgacg
    19021 agcccgatgg tgtgcgggcg cagccgctcg cgcttctcgg cgtagtacgc gatcagccgc
    19081 tcgcggtact cctccatcgg cagcaccagt atctcggctt cccggtgcgt gaccacgtcc
    19141 tcggggtcca cagtggaccg aggctgcagc agctcgtcga agttgttcgg gtgcccgcag
    19201 ctctcgcaca gcccgccccg gctctccacc aggcagaccg ggcaatatcc gcagaccagg
    19261 ccctcgacga ggaactcgcc gtcgcgctcc gagtagggca gcagcacctt cttgagccgg
    19321 aacttccctg ccgcgtgcag cgcggtgacg aagtccagcg acgaggcgcg gtagcggtcg
    19381 tcgtacggcg cgaacccgtc gagcgagatc cccatgtcga cgagggtctg cttgatgtcg
    19441 tgccaggact gtccacaaag gtcttcgggg gtacggcctt tgcgccgagc actcgccagt
    19501 acgtacgttt ggctgtcatc ggttccactc gagaacacca ccggacggcc cagcgcccgc
    19561 agatagcgcg cgtgcacgtc ggccgccatg aacgggccag ccaggtgccc gacgtgcaga
    19621 tcgccgttcg acgtcggcgg ggtgtcgatg acgatcgctg tgcgctggct cacttgtcac
    19681 gctcggcgaa ccgctcggtc atgtctttgt cccaccagac cgagtacatc tggaagtcct
    19741 cgtcgccgtc gttgatcacc tggtgatcgg tgtgcggcgg gaagtgcacc acgtcgcccg
    19801 gcacgaactc ggtgcgctca ccctgcgatt cgaggatcgc cttgcccgag atcgcgatga
    19861 agatctcgta ctcgtggtgg gcgtgcttga ccgacgaggt gccggggcgg atcacgttcc
    19921 aggcgccttc gaacggcgcg ttgagggcgt cccacgggac caggcgctgg gaatggttgt
    19981 tgtccggccc cagccgttcc cggtcgagct tgcgaatctc cactgtccgt tttctccctc
    20041 tagttggccg ttaccgaggt ggaagtcagc gtgaccgcgc ggccggcgcg atcggcgagg
    20101 atgtcgtgcg cgatatcgga tccgcgcgcg gcgagcatgc tcagcagcga gtcgccgatg
    20161 ccgtgcgtgg cctcgttcac gccctgcagg tagcaggccg cgtccgcctg accggggatc
    20221 ttgagccggt agtccctggt gacctcgatc ttctccaggc ccagcgaggc ggccaggtca
    20281 cgcaccatcg tcggcatctc cctgacgaac ccggtgccga gcagcaccag gtcacagcgg
    20341 agctcctcga ccgtgccggt ccggcggtcg gccagctcga gcacgacctc gccgccctct
    20401 tcgcgcgccg aggcgatgtc ggtcatcgtc tcgatgcgca gcttgccctt gccggtcatg
    20461 cggtcgaggt acacctgctt gtacagatcg tccaaggtgg acgcggccag gccggagtag
    20521 ttgctgatgt gcatctcgcg caggatctgc tcgcgggcgt ccggtggcgc gtcgaagaag
    20581 tcgtcgaccg cggaggggaa gtacagctcg ttcgtgaact tgctgttctc gtaggtcttc
    20641 aacccgatcg agcgcatcac cagcgtccgg tgacagccgg gcaggtcgtt gccgaccgcg
    20701 tcgaacatct ccgccgcgct ctgcgcgccg ccgatgacca ccacccggta cggcacgtcg
    20761 ccgggcagtc cggcgatcct cggcaggtac tgcgtgctgt gaatgatccg atcatcgggc
    20821 agaccggcga agacgggcgg gatatacggg tcccgcccgg cgccgacgac caaatagcgg
    20881 ctgccgatcg tcgaaccgtc cgcgaggtgg gtgacccagc cggtcagcgt gccatcggag
    20941 tcgcgccgag gctcgatctc ctgacactcc cgcgcacatt ccagccggac tttttccagc
    21001 gaattcgcca cccactggtg ataatcggac atctccacgc gatagggcca gaaattgccc
    21061 atgttgatga actcgttgag tctgccgatc gagtgaagat agttgacgaa cgagaatttg
    21121 ctgcgcgggt tgcgcagggt gaccaggtct ttcaggaagg aaacctggct ctgcgcctcc
    21181 ggcagcagca ttccccgctg ccaggcgacc gtctcgttcc
//
