BGC0002759: brevione E biosynthetic gene cluster from Penicillium bialowiezense CBS 227.28
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Location: 1 - 41,588 nt. (total: 41,588 nt).
This entry is originally from NCBI GenBank LC719581.1.

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core biosynthetic genes
additional biosynthetic genes
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0002759
Short description brevione E biosynthetic gene cluster from Penicillium bialowiezense CBS 227.28
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • terpene (Sesquiterpene)
  • PKS (Iterative type I)
Loci
LC719581.1
1 - 41588
via Heterologous expression
Compounds
  • brevione E
  • isobrevione E
Species Penicillium bialowiezense CBS 227.28 [taxonomy]
References
Chemical products information
brevione E Evidence: NMR
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Chemical database entries
NPAtlas
PubCHEM
ChemSpider
isobrevione E Evidence: NMR
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List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BDO47151.1
  • brvA
 101 - 6590 (-) polyketide synthase
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    • BDO47152.1
    • brvB
    		 7688 - 8810 (-) prenyltransferase
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      • BDO47153.1
      • brvC
      		 10836 - 12119 (-) geranylgeranyl pyrophosphate synthase BrvC
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        • BDO47154.1
        • brvD
        		 12967 - 14846 (+) cytochrome P450 monooxygenase BrvD
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          • BDO47155.1
          • brvE
          		 15571 - 17164 (-) FAD-dependent monooxygenase BrvE
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            • BDO47156.1
            • brvF
            		 18285 - 19077 (-) terpene cyclase
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              • BDO47157.1
              • brvG
              		 19732 - 20766 (-) short-chain dehydrogenase/reductase BrvG
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                • BDO47158.1
                • brvH
                		 22243 - 24165 (+) cytochrome P450 monooxygenase BrvH
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                  • BDO47159.1
                  • brvI
                  		 25563 - 27346 (-) cytochrome P450 monooxygenase BrvI
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                    • BDO47160.1
                    • brvJ
                    		 28367 - 29263 (-) 2OG-Fe(II)-dependent dioxygenase BrvJ
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                      • BDO47161.1
                      • brvK
                      		 30387 - 32102 (-) putative glycosyl hydrolase BrvK
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                        • BDO47162.1
                        • brvL
                        		 33154 - 34702 (+) acetyltransferase BrvL
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                          • BDO47163.1
                          • brvM
                          		 35321 - 37170 (+) major facilitator superfamily transporter BrvM
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                            • BDO47164.1
                            • brvN
                            		 37330 - 38420 (-) metallo-hydrolase BrvN
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                              • BDO47165.1
                              • brvO
                              		 40033 - 41488 (+) SAM-dependent decarboxylase BrvO
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                                Biosynthesis information

                                No biosynthesis information available for this record.

                                Annotation changelog

                                Entry version: 1

                                Date
                                Changes
                                Submitters
                                Reviewers
                                2023-11-14
                                Created new entry for brevione BGC.
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                2023-11-14
                                Reviewed and approved.
                                • (ID: C62OJVVH7XOTOTFZSJT727YU)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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