LOCUS       BGC0002812             15710 bp    DNA     linear   PLN 27-FEB-2017
DEFINITION  Colletotrichum higginsianum IMI 349063 chromosome 4, whole genome
            shotgun sequence.
ACCESSION   BGC0002812
VERSION     BGC0002812
KEYWORDS    .
SOURCE      Colletotrichum higginsianum IMI 349063
  ORGANISM  Colletotrichum higginsianum IMI 349063
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Sordariomycetes; Hypocreomycetidae; Glomerellales; Glomerellaceae;
            Colletotrichum; Colletotrichum destructivum species complex.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 18:24:02
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15710
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15710
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[10789:14192]"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10790..14192
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     protocluster    1..15710
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[3307:9935]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      3308..9935
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
     cand_cluster    1..15710
                     /SMILES="CC(=O)NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="neighbouring"
                     /product="NRPS-like"
                     /product="T1PKS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     subregion       1..15710
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002812"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..15710
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            1..1895
                     /locus_tag="CH63R_05468"
     mRNA            join(1..131,192..274,447..872,933..1472,1546..1895)
                     /locus_tag="CH63R_05468"
                     /product="RadH flavin-dependent halogenase"
     CDS             join(1..131,192..274,447..872,933..1472,1546..1895)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Trp_halogenase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1119:halogenase (Score: 311; E-value: 2.5e-94)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="CH63R_05468"
                     /product="RadH flavin-dependent halogenase"
                     /protein_id="OBR09776.1"
                     /sec_met_domain="Trp_halogenase (E-value: 1.7e-18,
                     bitscore: 54.7, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPAIPERCTVLVIGGGPGGSYAASALAREGIDVVVLEGDKFPRY
                     HIGESMLASMRHMLRFIDLEAKFDSYDTDFLAAGGPNNYAWNVVRSEADQLMFHHAGEC
                     GAKIFDAVKIKSIRFEDATTVPEGEPNLNPGRPVAAVYEVAETKETGEIAFDYVVDASG
                     RVGLLSTKYMKNRRYNQGLKNVANWGYWEGCNKFSPGTPRENSPFFEALTDESGWAWFI
                     PLHNGKASVGVVMNQKLAAHKKQQGGFNSTEFYHESLKLAPELLSVLVGDGKFVSDVKS
                     ASDYSYSASSYAFPNARIVGDAGCFIDPFFSSGVHIALTGALSAATTIAASIRGDSEEA
                     TAAEWHSKKVAAAYTRFLLVVLSAYKQMRFQGDPVLSDFDEDNFDRAFSFFRPIIQGTA
                     DAANGNLSQDELNKTLEFCAHAFEPVNPEANQEKVMKAVSAAPAGSDYNPDLSVEEQNA
                     VNHIRARKMMRTEDTFNINTFGTDSIVGYVPNLVRGSLGLKKAETNGVVAA"
     gene            complement(3308..9935)
                     /locus_tag="CH63R_05469"
     mRNA            complement(join(3308..3769,3834..3913,3971..4336,
                     4415..9242,9303..9935))
                     /locus_tag="CH63R_05469"
                     /product="Polyketide synthase"
     CDS             complement(join(3308..3769,3834..3913,3971..4336,
                     4415..9242,9303..9935))
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (388-809). E-value:
                     2.3e-146. Score: 479.8. Matches aSDomain:
                     nrpspksdomains_CH63R_05469_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (914-1212). E-value: 8.6e-59.
                     Score: 191.2. Matches aSDomain:
                     nrpspksdomains_CH63R_05469_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH2 (1320-1517). E-value: 2.9e-08.
                     Score: 25.2. Matches aSDomain:
                     nrpspksdomains_CH63R_05469_PKS_DH2.1"
                     /NRPS_PKS="Domain: PP-binding (1662-1716). E-value:
                     3.1e-11. Score: 35.6. Matches aSDomain:
                     nrpspksdomains_CH63R_05469_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 235.3; E-value:
                     2.2e-71)"
                     /gene_kind="biosynthetic"
                     /locus_tag="CH63R_05469"
                     /product="Polyketide synthase"
                     /protein_id="OBR09777.1"
                     /sec_met_domain="itr_KS (E-value: 6.1e-156, bitscore:
                     507.4, seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 6.2e-60, bitscore: 191.2,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.2e-12, bitscore:
                     35.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLMPSNTTLSAAVFSPQSSPPPSTHLSYIRTRLLEDPSLEPLKD
                     AIVNLPETWQTLTASRQDVSRLELASKAIGSFPQWIETGESDVLEQDMSGIITLPLLTT
                     IHIVQYLSFIRGAGLSHSDFLRSVVQRGGVQGYCIGLLSAVIAAASRDEQELVQHAVAG
                     LHLSLAIGAFGDLGQASSASSSPSSTRTLQISLRNHDDVHEILGRFPTAILSTITEPRT
                     VCLTAPEDDMEALKAHADKQGLRPRMMHIRSNLHNPENETLARQCYDLSRTIPFPTSDL
                     LQVPVRSNRTDESLVGEGQLLSQEIITTVLTSRCDWSQVIQSLARDLAQTKEKRHSLAL
                     FGIGDAVSTPPFQQLGLEVSKIHVLSTMHASPAPIVPTSNLDQFPDDAIAIVGASCRLP
                     GANSLDELWEVISQGQTRLEKLRTDRFDLGGSHRAAQDRDWVTKREFYGNFIDDVRGFD
                     NAFFGISPREAAYMDPQQRILLETAFEAMDSSGYLRHHRRERGDPVGCFIGASYTEYLE
                     NTSAYTPSAFTATGTIRAFLSGKISYHFGWTGPSEVIDTACSASLVAVHRACRAIAAGE
                     CPVALAGGVNIITGVNNYFDLAKAGFLSKTGQCKPFDDSADGYCRADGVGLVVLKSLRQ
                     AVSDGDHIMGVIPSVATNQGGIGAPGITVPDGICQKALYSTLLRKSGIKADQVSYVEAH
                     GTGTQVGDPIEISSIRQVFGGSQRTKPLYIGSLKANIGHSETAAGVASLLKVLAMLRHR
                     AIPPLQGFKRLNHKIPPLEEDRIRVPTGLVPWNAVSRVACINSYGASGSNSALLCSEWY
                     EEHHQGPADIVGPVTREYPILLSATSAESLQRYAKALAAHLAKDIKGVTLGDLSFTLSE
                     RRKHHSVRWSTTSTDLTALIRQLQTCGPQDFSIVPRIPKKSVLVFSGQSKTTIGVDPSV
                     RQQNPRLEHYIRTCNEILRGFGCPDILPFLGRTEPISDPTVLQCGTVAVQYACARCWID
                     GGLEVAGVVGHSLGELTALAVSGVLSLEDTLKVVFTRAELIKAHWGAERGTMMAIHADQ
                     ETVQSIMDAVEATVDSPDEALEIACYNSATSHVVVGKESSVVSAEKILQQDARYHGIRF
                     QRLNVSHGFHSRFTQPLLDGLSQLESTLVFNDPAIPLETSTRDSVPFTPKPTAQYLANH
                     ARDPVFFYDAVRRLEQRLGDCVWLEAGWATPIIAMTKRATSRLDSHTFQSVPSIATAAS
                     DLWLQGIAATHWSFLTPKESGLKHIHLPPYSFDHPEYWISHVDRAMEERKAVRDLKDDS
                     ISQHGSQQVQQLVSHISTDGTSYQFRINTNTERYTRIVQGHAVRQNPLCPASMYMEAAI
                     MGIEQLGASARGKTIIFEDVVFDRPLGCGPDLDVHLSIDGPPNADDGSWRYTVRSSLGQ
                     AHSKGSFHATNSENPDFQVYGMLLLDKMNSLRDDPEAERLKTATAYSIFSAVVEYASLL
                     QGISRITLSSRQSLAEIIVPKTAFEASESTVTKFYDAITLDTYIQVLGLLVNSNAGSSS
                     EDEIYVASSIGKMVVSPTDFEKPQTWTVYATYSAVDHKTSTGAVFVFSEDKKLRAFATG
                     VSFVKIQAARLERVLKAANSGAAVPAPVEAAPINHSIARPGLDSGQPNHHQAVVRNADE
                     VSSSSTDLTAVNSRRGSDTSRKTTELKSILSAYTGVPAAELKDDQNLGDIGLDSLGSME
                     LADEIESKLGLSVQADDLLLCSVGSLLKLLHPSDGAAAVEDQADSTNTTSDFAADEITM
                     TPSSLGLQTASGLPASQSGSWTRPSSPLDSRFRLETAVYKAVDGLDILADLYIPAEVPP
                     QPMIAALLIHGGGHLTLSRKAVRTAQIRFLLANGILPVSVDYRLCPQVNVIDGPMTDVR
                     DACSWLQSDLPRVMAAKGFSIDTSRYVVVGWSTGGTLAMTTAWSLTQARIRPPSAILAF
                     YCPVEYNPQAPTIMGHEVEKRTMSLTEIRKLLSTEPTANHAPNSLDTTKLGWVRRGDPR
                     SELVRALVKEDRGMSILFNGLPPDGEELPYPDADRAEAFSPLCQVRKGNYRVPTYLIIG
                     DQDDIASFKKGQEFARALEEHGVRSGFLPVEGAKHIFDLGLVPGSEGWNAGVGPGYEFL
                     LKELESNQRGFA"
     CDS_motif       complement(4050..4100)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CH63R_05469_0007"
                     /evalue="1.80E-04"
                     /label="NRPS-te1"
                     /locus_tag="CH63R_05469"
                     /protein_end="1916"
                     /protein_start="1899"
                     /score="14.1"
                     /tool="antismash"
                     /translation="YVVVGWSTGGTLAMTTA"
     CDS_motif       complement(4164..4196)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CH63R_05469_0006"
                     /evalue="9.90E+01"
                     /label="PKSI-KS_m3"
                     /locus_tag="CH63R_05469"
                     /protein_end="1878"
                     /protein_start="1867"
                     /score="-3.2"
                     /tool="antismash"
                     /translation="GPMTDVRDACS"
     aSDomain        complement(4728..4889)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CH63R_05469_PP-binding.1"
                     /evalue="3.10E-11"
                     /label="CH63R_05469_PP-binding.1"
                     /locus_tag="CH63R_05469"
                     /protein_end="1716"
                     /protein_start="1662"
                     /score="35.6"
                     /tool="antismash"
                     /translation="ELKSILSAYTGVPAAELKDDQNLGDIGLDSLGSMELADEIESKLG
                     LSVQADDLL"
     aSModule        complement(4728..8711)
                     /complete
                     /domains="nrpspksdomains_CH63R_05469_PKS_KS.1"
                     /domains="nrpspksdomains_CH63R_05469_PKS_AT.1"
                     /domains="nrpspksdomains_CH63R_05469_PKS_DH2.1"
                     /domains="nrpspksdomains_CH63R_05469_PP-binding.1"
                     /iterative
                     /locus_tags="CH63R_05469"
                     /monomer_pairings="mal -> mal"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(5325..5915)
                     /aSDomain="PKS_DH2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CH63R_05469_PKS_DH2.1"
                     /evalue="2.90E-08"
                     /label="CH63R_05469_PKS_DH2.1"
                     /locus_tag="CH63R_05469"
                     /protein_end="1517"
                     /protein_start="1320"
                     /score="25.2"
                     /tool="antismash"
                     /translation="IVQGHAVRQNPLCPASMYMEAAIMGIEQLGASARGKTIIFEDVVF
                     DRPLGCGPDLDVHLSIDGPPNADDGSWRYTVRSSLGQAHSKGSFHATNSENPDFQVYGM
                     LLLDKMNSLRDDPEAERLKTATAYSIFSAVVEYASLLQGISRITLSSRQSLAEIIVPKT
                     AFEASESTVTKFYDAITLDTYIQVLGLLVNSNAG"
     aSDomain        complement(6240..7133)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CH63R_05469_PKS_AT.1"
                     /evalue="8.60E-59"
                     /label="CH63R_05469_PKS_AT.1"
                     /locus_tag="CH63R_05469"
                     /protein_end="1212"
                     /protein_start="914"
                     /score="191.2"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="VFSGQSKTTIGVDPSVRQQNPRLEHYIRTCNEILRGFGCPDILPF
                     LGRTEPISDPTVLQCGTVAVQYACARCWIDGGLEVAGVVGHSLGELTALAVSGVLSLED
                     TLKVVFTRAELIKAHWGAERGTMMAIHADQETVQSIMDAVEATVDSPDEALEIACYNSA
                     TSHVVVGKESSVVSAEKILQQDARYHGIRFQRLNVSHGFHSRFTQPLLDGLSQLESTLV
                     FNDPAIPLETSTRDSVPFTPKPTAQYLANHARDPVFFYDAVRRLEQRLGDCVWLEAGWA
                     TPIIAMTKRATSRLDSH"
     CDS_motif       complement(6786..6887)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CH63R_05469_0005"
                     /evalue="7.50E-14"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="CH63R_05469"
                     /protein_end="1030"
                     /protein_start="996"
                     /score="43.7"
                     /tool="antismash"
                     /translation="VVGHSLGELTALAVSGVLSLEDTLKVVFTRAELI"
     aSDomain        complement(7449..8711)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CH63R_05469_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="2.30E-146"
                     /label="CH63R_05469_PKS_KS.1"
                     /locus_tag="CH63R_05469"
                     /protein_end="809"
                     /protein_start="388"
                     /score="479.8"
                     /tool="antismash"
                     /translation="IAIVGASCRLPGANSLDELWEVISQGQTRLEKLRTDRFDLGGSHR
                     AAQDRDWVTKREFYGNFIDDVRGFDNAFFGISPREAAYMDPQQRILLETAFEAMDSSGY
                     LRHHRRERGDPVGCFIGASYTEYLENTSAYTPSAFTATGTIRAFLSGKISYHFGWTGPS
                     EVIDTACSASLVAVHRACRAIAAGECPVALAGGVNIITGVNNYFDLAKAGFLSKTGQCK
                     PFDDSADGYCRADGVGLVVLKSLRQAVSDGDHIMGVIPSVATNQGGIGAPGITVPDGIC
                     QKALYSTLLRKSGIKADQVSYVEAHGTGTQVGDPIEISSIRQVFGGSQRTKPLYIGSLK
                     ANIGHSETAAGVASLLKVLAMLRHRAIPPLQGFKRLNHKIPPLEEDRIRVPTGLVPWNA
                     VSRVACINSYGASGSNSALLCS"
     CDS_motif       complement(7659..7703)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CH63R_05469_0004"
                     /evalue="5.90E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="CH63R_05469"
                     /protein_end="739"
                     /protein_start="724"
                     /score="9.5"
                     /tool="antismash"
                     /translation="GSLKANIGHSETAAG"
     CDS_motif       complement(7761..7808)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CH63R_05469_0003"
                     /evalue="5.20E-05"
                     /label="PKSI-KS_m5"
                     /locus_tag="CH63R_05469"
                     /protein_end="705"
                     /protein_start="689"
                     /score="15.0"
                     /tool="antismash"
                     /translation="YVEAHGTGTQVGDPIE"
     CDS_motif       complement(8004..8042)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CH63R_05469_0002"
                     /evalue="8.00E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="CH63R_05469"
                     /protein_end="624"
                     /protein_start="611"
                     /score="12.6"
                     /tool="antismash"
                     /translation="FDDSADGYCRADG"
     CDS_motif       complement(8184..8231)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CH63R_05469_0001"
                     /evalue="3.60E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="CH63R_05469"
                     /protein_end="564"
                     /protein_start="548"
                     /score="16.0"
                     /tool="antismash"
                     /translation="GPSEVIDTACSASLVA"
     gene            complement(10790..14192)
                     /locus_tag="CH63R_05470"
     mRNA            complement(join(10790..11197,11275..13722,13812..14192))
                     /locus_tag="CH63R_05470"
                     /product="Gluconate kinase"
     CDS             complement(join(10790..11197,11275..13722,13812..14192))
                     /NRPS_PKS="Domain: AMP-binding (43-365). E-value: 1.3e-36.
                     Score: 117.9. Matches aSDomain:
                     nrpspksdomains_CH63R_05470_AMP-binding.1"
                     /NRPS_PKS="Domain: PKS_PP (573-658). E-value: 4.1e-08.
                     Score: 25.3. Matches aSDomain:
                     nrpspksdomains_CH63R_05470_PKS_PP.1"
                     /NRPS_PKS="Domain: TD (703-957). E-value: 1.2e-30. Score:
                     98.4. Matches aSDomain: nrpspksdomains_CH63R_05470_TD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     117.6; E-value: 8.5e-36)"
                     /gene_kind="biosynthetic"
                     /locus_tag="CH63R_05470"
                     /product="Gluconate kinase"
                     /protein_id="OBR09778.1"
                     /sec_met_domain="AMP-binding (E-value: 6.1e-33, bitscore:
                     102.0, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 1.4e-26, bitscore:
                     81.2, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAITEPKAAAGSIRPFKRPAVNFESDKRLDGHLHSIPELIDFNA
                     THNPSHPFCVQAKPTDPFDTVTHAEFKVAVSRCAAWLKQNLPLRQASGGDSAATKMAPV
                     ALFMESDVGLVIHEFALMSIGVPPLVLSARLPPAAINALMEATSAGSFIVSQRLSEPAK
                     PALAALASKGISTHIANRYDAFYEPHADASSVPAFESPEDRNSVVLLLHSSGTTGFPKP
                     IPLTHRQLLFALNCHGFDTEEQAQGLNLSTLPLFHGFGLVAPGLSLSAGKPTLYPVSDG
                     IPNAVSIIELVKKTKARSMMTVPFLLDAICDLPDDEGIKALAHMDFVGTGGAALGAGVG
                     DRLAAGGVKLLNFYGTTEAGHLSLIFAPTDSYDWKYFRLRNDMKFTVAELEPRDGERRF
                     RLTVFPFGDGEGIEIADQLVRNEQYPETDFAAVGRDDDVIVLATGEKADPLILETMLSE
                     APAVKSAVAFGENQFNLGVIVEPREPLLAPGDEEAFRETIWPIVTAAGQKMDASARVPS
                     PDAIIVVPGGKVVPRTDKGSIARKETYALFDEEIKAVYERLVQAATESVGPLDLDNLEE
                     NIKALVHEHLRLQTPISAWAVDDSLFDLGVDSLQALQLRRVLIAAASKTEGLKDVDVAK
                     MIPSQFIYRNPSVREMAAAILQRSSGGGGETDSSGDAVKEVKELVDQYSLGGASTEEEK
                     QPSSADHAVVLLTGSSGSLGSHCVADLARRPQVRRIICLIRKEKGANAPPPPGGGPFDR
                     RTLKARGLDLAEEEWSKIATLEVDPTAERLGLMPMVYAAMQEKVTHVVHAAWPMNYLIP
                     LRSFRYQLQFLRSLLEFAAHAPGRTKRRLVFVSSIAAVAKIGLDNPGSAIPEAPVSPEE
                     AACGIGYADGKLACEKIVERAAEAYAGQLEVTSVRCGQITGAKGTGVWNTNEQIPMLLK
                     SAQSLGSLPQLSGELSWIPVDDAASVISEIAFSPEPLPITLHLDNPTRQPWSDLMESFG
                     RQLNLKPSVPFQEWLEQVAGAEQDDEKLPVKKLYAFFKHLFQPVACGSVVLDTSVAKTR
                     SGTLRDLGAVDDATLHAYVKYWLDVGYLSR"
     aSDomain        complement(join(11156..11197,11275..11994))
                     /aSDomain="TD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CH63R_05470_TD.1"
                     /evalue="1.20E-30"
                     /label="CH63R_05470_TD.1"
                     /locus_tag="CH63R_05470"
                     /protein_end="957"
                     /protein_start="703"
                     /score="98.4"
                     /tool="antismash"
                     /translation="VLLTGSSGSLGSHCVADLARRPQVRRIICLIRKEKGANAPPPPGG
                     GPFDRRTLKARGLDLAEEEWSKIATLEVDPTAERLGLMPMVYAAMQEKVTHVVHAAWPM
                     NYLIPLRSFRYQLQFLRSLLEFAAHAPGRTKRRLVFVSSIAAVAKIGLDNPGSAIPEAP
                     VSPEEAACGIGYADGKLACEKIVERAAEAYAGQLEVTSVRCGQITGAKGTGVWNTNEQI
                     PMLLKSAQSLGSLPQLSGELSWIPVDDAASVI"
     aSModule        complement(11156..14063)
                     /complete
                     /domains="nrpspksdomains_CH63R_05470_AMP-binding.1"
                     /domains="nrpspksdomains_CH63R_05470_PKS_PP.1"
                     /domains="nrpspksdomains_CH63R_05470_TD.1"
                     /final_module
                     /locus_tags="CH63R_05470"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     aSDomain        complement(12130..12384)
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CH63R_05470_PKS_PP.1"
                     /evalue="4.10E-08"
                     /label="CH63R_05470_PKS_PP.1"
                     /locus_tag="CH63R_05470"
                     /protein_end="658"
                     /protein_start="573"
                     /score="25.3"
                     /tool="antismash"
                     /translation="LEENIKALVHEHLRLQTPISAWAVDDSLFDLGVDSLQALQLRRVL
                     IAAASKTEGLKDVDVAKMIPSQFIYRNPSVREMAAAILQR"
     aSDomain        complement(join(13009..13722,13812..14063))
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CH63R_05470_AMP-binding.1"
                     /evalue="1.30E-36"
                     /label="CH63R_05470_AMP-binding.1"
                     /locus_tag="CH63R_05470"
                     /protein_end="365"
                     /protein_start="43"
                     /score="117.9"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="NATHNPSHPFCVQAKPTDPFDTVTHAEFKVAVSRCAAWLKQNLPL
                     RQASGGDSAATKMAPVALFMESDVGLVIHEFALMSIGVPPLVLSARLPPAAINALMEAT
                     SAGSFIVSQRLSEPAKPALAALASKGISTHIANRYDAFYEPHADASSVPAFESPEDRNS
                     VVLLLHSSGTTGFPKPIPLTHRQLLFALNCHGFDTEEQAQGLNLSTLPLFHGFGLVAPG
                     LSLSAGKPTLYPVSDGIPNAVSIIELVKKTKARSMMTVPFLLDAICDLPDDEGIKALAH
                     MDFVGTGGAALGAGVGDRLAAGGVKLLNFYGTTEAGHLSLI"
     gene            14688..15710
                     /locus_tag="CH63R_05471"
     mRNA            14688..15710
                     /locus_tag="CH63R_05471"
                     /product="4-hydroxybenzoate polyprenyl transferase"
     CDS             14688..15710
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ubiA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="CH63R_05471"
                     /product="4-hydroxybenzoate polyprenyl transferase"
                     /protein_id="OBR09779.1"
                     /sec_met_domain="ubiA (E-value: 1.5e-27, bitscore: 84.8,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPSSSKATAKESPEKKPLIGEAPPYKPPTKGFLSILPASWVPYA
                     ELTRIHQPHGIYMIYFPHLVGLAYAASVQQADLAMPPSELAYRAAVMLGWTVFWRSGIC
                     VWNDNIDQDFDRKTARCRNRPIARGAISTAQGHVFALVLNLIAFAWLRLLPRECTLVAL
                     GSTVLGMIYPFGKRFTYYPQVILGSTLGSTVALSAYSVGLPAVSPPYLGTTACLAAAVL
                     LLVVFYDTVYARQDTADDLKSGVKGMAVRFRDHIEGLLAVLAVSIAALLTTAGVLMEAQ
                     QYYYVFSVGGLTMGLISLVALTHWDLLPSWAGSSGWCYALAIANLIGGMASQYVLKGAA
                     "
ORIGIN
        1 atgtctcctg ctattcccga gagatgcacc gtcttggtga ttggtggcgg accgggaggc
       61 tcctatgctg cctccgccct ggccagagag ggcattgatg ttgtcgtcct cgagggcgac
      121 aagttcccca ggtatgttcc atttcagaga gcgggtgttt ttaacactgt tctcacctga
      181 gacgtgacta gataccacat tggcgagagc atgctcgcat ccatgcgtca tatgctcagg
      241 tttatcgact tggaagccaa gtttgactcc tatggtttta tcaagaaggc aagaaatcat
      301 gactgacggc ccagtttgct ccaagatgtt tgtgctgaca cgtctatagc ctggtgcgtc
      361 tttcaagctc aacaaggaca agcgtcctgg atgtgagtca atgctcgatg aaggctgttg
      421 agagagccgt ggctgacttc tcgtagacac cgacttcttg gctgctggcg gcccaaataa
      481 ctatgcctgg aacgtggttc gctccgaggc cgaccagctc atgttccacc acgccggcga
      541 gtgcggcgcc aagatctttg acgccgtcaa gatcaagtcg atccggttcg aggacgccac
      601 cacggttccc gagggcgagc cgaacctcaa cccaggccgt ccggtcgccg ccgtctacga
      661 ggtcgcggaa accaaggaga ccggcgagat cgccttcgac tacgtcgtcg acgccagtgg
      721 ccgcgtcggg ctgctgagca caaagtacat gaagaaccgt cgttacaacc agggtctcaa
      781 gaacgtcgcc aactggggtt actgggaggg gtgcaacaag ttctccccgg gcacccccag
      841 agagaactcg ccctttttcg aggccttgac aggtaagttc gcgagctggc ggacactgtt
      901 tcctggtagt ggatttgcta atgccacgtc agatgagagc ggctgggctt ggttcatccc
      961 cctccacaac ggaaaggcct ccgtcggtgt cgtcatgaac cagaagctgg cggcgcacaa
     1021 gaaacagcaa ggcgggttca actcgaccga gttctaccac gagagcctga agctcgcccc
     1081 cgagcttctg tccgtcctcg tcggggacgg caagttcgtc agcgacgtca agtcggcctc
     1141 ggactactcc tacagcgcct cgtcctacgc gttcccgaat gcccgcatcg tgggcgacgc
     1201 gggctgcttc atcgatccct tcttctcgtc cggcgtccac atcgccctca cgggagccct
     1261 ctcggccgcc accaccatcg ccgcgtccat ccgcggcgac agcgaagagg caacggccgc
     1321 cgagtggcac agcaagaagg tcgcggcggc ctacacgcgg ttcctgctcg tggtgctgag
     1381 cgcctacaag cagatgcgct tccaggggga tcccgtcctc agcgacttcg acgaggacaa
     1441 ctttgacaga gccttttctt tcttcaggcc tagtaagttc agagtccaaa ggagagagac
     1501 ttttgggata aagcttgcag gggggtccta acatggaagc gatagtcatc cagggaacgg
     1561 cggacgctgc caacggtaac ctctcgcagg acgagctcaa caagacgctc gagttctgcg
     1621 cgcacgcctt cgagcccgtc aaccccgaag cgaaccagga gaaggtcatg aaggccgtct
     1681 cggccgcccc ggccggatcg gactacaacc ccgacttgtc ggtcgaggag cagaacgcag
     1741 tgaatcacat ccgcgcccga aagatgatgc gcacggagga caccttcaac atcaacactt
     1801 tcggcaccga ctccatcgtt ggatatgtgc ccaacctggt caggggcagc ctgggcttga
     1861 agaaggcgga gacgaatgga gtggtggcgg cttgagacgt ttgctttggg atgttcattt
     1921 cattcacgtc cttcatcctg taggagttat tagacactag atgattgtgt agcgagttag
     1981 gacaattgag tttaaagagc accacgccgg cagcagtctc ttcaacgcga gtccaatgag
     2041 aaaacgcaaa caatgttaaa catctctgct acctgtttcc atgttcccac cttggagcgc
     2101 cgtcctttag atgatgtcgt gaacgtgtgg aaagctaggt ataatgtgta cagtcccgcg
     2161 taggttttaa gcttgtgaac agtgcggaac aagattaatt aagcgatggt aacattggcg
     2221 agatataccg actgagcctt gggtcctaat ttgtaattta agtttggcac gttttgatct
     2281 atgtgataag gaagcatagc aatggctcac aagagtacag caaagatgct ttgggtatga
     2341 gagtaactgc atttcatcga acacacgcta tgttccagga tcaagtatga tggcatggcc
     2401 cttgcaatac cttcagcatg atctccctgg cgtcaatacg tcaataccaa gcagtgcctt
     2461 gcagcgcgta gatcaaacca cggagtgccg agaatagaag tctcggcgtg ttctcgcttt
     2521 gtagtagagt gtgtatgatg actattttga ccatgaccaa aaacatccat cctgggagga
     2581 gacaagggtg ctgttgtggt tctagatggc agtttgatag gtccgtttat gagcgcgtct
     2641 ggccggaaac caccgaatac ggcaaggaaa accaccgaac cggagagcag gccgagtcta
     2701 gacaccgaat cagagggtta agggggaaaa gcgccgaaaa tacggagacg ggctgtgata
     2761 cttggcacga tggcccaccg aattagcgga ctcagatata gggttagtcg aggacacgaa
     2821 cagcgacgaa ggcaggaaag gagcaggggc tcggtcagaa gtcacgccta acatggagtt
     2881 tgtctgtttc tgttgaaaag aaatcgaatg tgtgtatgca gtcacatgca gcctgttggg
     2941 gaggccactc acctggacgt gtattcgaac agagcgtttt gcctcttagt ttccaaaagt
     3001 gttggtagtt gaggtaaaaa gttgaataga cagggccgaa actgagttgc aacgattcat
     3061 cttttctaca acgatgtaaa ctggaaagca agtgatcatt atgtggtgtt ctcacatgaa
     3121 ttcaaaggtt tttcactgtt tacattacac aactagaact aaacacaagc tgtctatatc
     3181 gctttatcag tgacgctaat ccagcgacaa atcgtacaaa ttaggcaaag aaaaagcagg
     3241 aaaaacaggc aaatataccc aaaggtacca acagaaaaca ggtccttcgc gaaacatgtc
     3301 gagttgttca ggcaaagcca cgctggttgc tctcgagctc cttcagcagg aactcgtagc
     3361 cgggaccaac tccagcgttc catccctcac tcccggggac gaggccgagg tcgaagatgt
     3421 gcttcgcccc ctccacgggc aggaatccgc tcctcacgcc gtgctcctcc aacgcccgtg
     3481 cgaactcctg ccccttcttg aacgacgcga tgtcatcttg gtccccgatg atcaggtatg
     3541 tcgggacgcg gtagttcccc ttgcgcacct ggcagagcgg gctgaaggcc tcggcgcgat
     3601 cggcgtccgg gtaagggagc tcctcgccgt ccggaggcag tccgttgaag aggatcgaca
     3661 tgcctctatc ctctttgacc agggcgcgta cgagctccga ccgcgggtct ccgcgcctga
     3721 cccagccgag cttggtcgtg tcgagactat tgggtgcgtg gttggcagtc tgggggtaaa
     3781 aggggttagg aatcgatgat tgcaatttga gcatgggagt agagatgact tactggttca
     3841 gtggagagga gtttgcgaat ttcggtcagg gacattgtcc gcttttcgac ttcgtgaccc
     3901 attattgtcg gcgctggagg aactgctgtc agtggccaca tgtgttgacg ggtgaatttc
     3961 aagaacgtac cttgaggatt gtactcaacc ggacagtaaa aggcgagtat agccgatgga
     4021 ggacggatac gggcttgcgt tagactccac gccgtggtca tggcgagcgt gcctccggta
     4081 gaccagccga cgaccacata tctcgaagtg tcgatactga atccttttgc cgccatgacc
     4141 cggggcaggt cactttgcag ccaactacag gcgtcgcgaa cgtcggtcat agggccgtca
     4201 atgacgttga cctgagggca gagccggtag tccacactca cggggaggat cccgttggca
     4261 aggagaaacc tgatctgcgc ggtccggacg gcctttcggg acagcgtgag gtgcccaccg
     4321 ccatggatca gcagggcttt agcctaaaag tatcagccat gactatctct gtttggcata
     4381 ttgagaggcg cgcggggggg gggggacttc ataccagcga tcatcggttg agggggaacc
     4441 tccgctggga tatacaggtc ggccaggatg tcgagtccgt caactgcctt gtagactgcc
     4501 gtctccaagc ggaatctgga gtccagaggg ctcgacggcc ttgtccaaga gccgctctgg
     4561 ctagctggga gtccagaggc tgtctgaagc ccgagggacg acggtgtcat ggtgatttcg
     4621 tctgcagcaa agtcactcgt ggtatttgtg ctgtcggcct ggtcttcgac agctgctgcc
     4681 ccatccgagg gatgcaataa cttcagaagc gacccgacgc tgcagagcaa caagtcgtct
     4741 gcctgaacac tcagacccag ctttgactcg atctcgtccg ccaactccat cgagcccaac
     4801 gagtccagac cgatgtcgcc caggttctgg tcatccttga gctctgcggc gggaacaccg
     4861 gtgtaagcag agaggatgga tttgagttcc gtggtcttgc gggaagtgtc actgcctctc
     4921 ctggagttta cggcggtcaa atcagtgctg ctgctggaaa cttcgtcggc attccgaacc
     4981 acggcttgat ggtggttggg ctgaccggaa tccagtcccg ggcgagctat gctgtggtta
     5041 atgggagcgg cttccactgg ggctgggaca gcggcccccg agtttgccgc cttcaagaca
     5101 cgctccagcc tggcggcctg tattttgaca aaagaaactc ccgtggcaaa ggctcgcagc
     5161 ttcttgtcct cggagaagac gaacacggcg ccggtggagg tcttgtggtc gacggccgag
     5221 tacgtggcgt acacggtcca ggtctgcggc ttttcgaaat ccgtaggaga gacgaccatc
     5281 ttgccgatgc tggaggcgac gtagatctcg tcctccgagc tcgagccggc attgctattg
     5341 acaagcaggc cgaggacctg gatgtatgtg tcgagggtga ttgcgtcgta gaacttggtg
     5401 actgtgctct cggatgcttc aaaggccgtt ttcggaacga tgatctccgc caaagactgc
     5461 ctggacgata gcgttatcct cgagatgccc tgcagcaggc tcgcgtactc gactactgcg
     5521 gagaagattg aatatgcagt ggctgtcttg agcctctcgg cttcgggatc atctctcagc
     5581 gaattcatct tgtccaacaa cagcatcccg tacacctgga aatcggggtt ctcagagttc
     5641 gtcgcatgga acgatccctt agaatgagcc tgtcctaggg acgaccgaac ggtatacctc
     5701 catgagccgt cgtcggcgtt ggggggtccg tcgatactga ggtgaacgtc aagatcgggg
     5761 ccgcacccga ggggccggtc gaacacgaca tcctcaaaga tgattgtctt gcctctggca
     5821 gaagctccaa gctgctcgat gcccatgatt gcggcttcca tgtacatgga cgctggacac
     5881 agcggattct gccggacagc gtggccttgg acaatcctgg tgtagcgttc tgtgtttgtg
     5941 ttgatacgga actggtacga ggtaccatcg gtgctgatgt gactgacgag ttgttgcact
     6001 tgttggctac catgttggct gatggagtcg tcctttagat ctcttacagc tttacgctct
     6061 tccatggcgc gatccacatg agatatccag tactctgggt ggtcgaagct gtagggaggc
     6121 agatggatgt gcttcaagcc gctctccttg ggtgtcagga aactccagtg cgtggcggca
     6181 atgccctgaa gccaaagatc tgaggcggca gtggctatgg atgggaccga ctggaaggta
     6241 tgcgaatcga gacgagaagt ggccctcttg gtcatggcga tgatgggagt tgcccatccc
     6301 gcttccagcc agacgcagtc accaagcctc tgctctaacc gacggaccgc atcgtagaag
     6361 aacacggggt ctcgggcgtg gttggcgaga tactgggccg tgggcttggg ggtaaaggga
     6421 actgagtccc gggtgcttgt ctccagaggg atggcaggat cgttgaacac gagagtgctc
     6481 tctagctgcg aaagaccatc cagaagaggc tgcgtgaagc gggagtggaa gccgtggctc
     6541 acattcagcc gttggaatcg tatgccgtga taccgagcgt cttgttggag aatcttctcg
     6601 gcagagacaa cggaactctc tttacccacg acgacgtggc tggtggcgct gttgtagcag
     6661 gcaatctcca atgcttcgtc tggggagtcg actgttgctt cgaccgcgtc catgatggac
     6721 tgcacagtct cctgatccgc gtggatcgcc atcatcgtcc ctcgctcagc tccccaatgg
     6781 gccttgatca gctcggcccg tgtgaagaca accttcaacg tgtcttccag agacagcacg
     6841 cccgagacgg ccagtgccgt gagctctccc aggctgtggc cgacgacgcc ggcgacttcg
     6901 agcccgccgt cgatccagca ccgcgcgcag gcatattgta cggcaacggt gccgcattgc
     6961 aggaccgtgg ggtccgaaat gggctccgtc cggccgagga aaggcagtat gtcggggcag
     7021 ccgaagcctc tgagtatctc gttgcaggtc cggatgtagt gttcgaggcg gggattctgc
     7081 tggcgcacgg aggggtcaac gcctatggtc gttttgctct ggccggagaa gacgaggacg
     7141 gacttctttg ggatgcgagg tacaatggaa aagtcttgtg gcccgcatgt ttgcagctgg
     7201 cgtatgagtg cggtgaggtc ggtcgatgtc gttgaccagc ggacgctgtg atgtttgcgt
     7261 cgctcgctca gggtgaacga caagtcaccg agtgtcactc ccttgatgtc tttagcaaga
     7321 tgggcagcta aagctttggc atatctctgc aagctctcag ctgacgttgc actcaggaga
     7381 atgggatact ctcgggttac cggaccgacg atgtctgcag gcccctgatg gtgttcctca
     7441 taccactcgg agcagagaag tgcagagttg ctaccggaag caccatagct gttgatgcac
     7501 gcaacccgag agacggcgtt ccacggaacc aagccggtag ggacgcgtat cctgtcctct
     7561 tccaggggcg ggatcttgtg gttgagacgc ttgaagcctt gcagaggcgg gatggcccgg
     7621 tgacggagca tcgcgaggac cttgaggagg ctggccacgc ccgcggcggt ctcgctgtgg
     7681 ccgatattgg ccttgaggga gcctatgtat aacggtttcg tccgctgact gcccccaaag
     7741 acttggcgga tgctgctgat ctcaatgggg tccccgacct gcgtgcccgt cccgtgggcc
     7801 tcgacgtagg agacctggtc cgctttgatt cccgacttgc ggagaagagt gctgtagagc
     7861 gccttctggc agatgccgtc ggggacggtg atgccgggcg ccccgatgcc gccttggttc
     7921 gtggccacgg aggggatcac gcccatgatg tgatcgccat cggagaccgc ctggcggaga
     7981 gacttcagaa ccaccagtcc gacgccgtct gcgcggcagt agccgtcggc cgagtcgtca
     8041 aacggcttgc actggcccgt cttgctgagg aagccggcct tggcgaggtc gaagtagttg
     8101 ttcacgccgg tgatgatgtt gacgccgccc gccagggcaa cgggacactc gccggctgcg
     8161 atggcgcgac aggcccggtg gacggcgacg agcgaggccg agcacgccgt atcgatgacc
     8221 tcggagggcc ccgtccagcc gaagtggtag ctgatcttgc cggacaagaa ggcgcggatg
     8281 gtgccggtgg cggtgaaggc cgagggcgtg tatgcgctcg tgttctcgag atactcggtg
     8341 tagctggcgc cgatgaagca cccgacgggg tccccccgct cgcgccggtg atgccggagg
     8401 tagccgctcg agtccatggc ctcgaaggcc gtctccagca ggatccgctg ctgggggtcc
     8461 atatacgccg cctcgcgggg gctgatgccg aagaaggcgt tgtcgaagcc gcggacgtcg
     8521 tcgatgaagt tgccgtagaa ctcccgcttc gtcacccagt cgcggtcctg ggccgccctg
     8581 tgcgagcccc cgaggtcgaa acggtcggtc cggagcttct ccagccgggt ttggccctgc
     8641 gagatgacct cccagagctc gtctagagag ttggcgccgg ggagccggca cgaggcgccg
     8701 acgatggcga tggcgtcgtc tgggaactgg tctaggttgc tcgtagggac gatgggggcc
     8761 ggggaggcgt gcatggttga caagacgtgt attttcgaaa cctcgagccc gagttgttgg
     8821 aagggcggcg ttgagacggc gtcaccgatg ccgaaaaggg cgagactgtg acgcttttct
     8881 ttcgtctgtg caagatcccg agccagactc tggatgacct gagaccagtc gcatcgcgaa
     8941 gtaagaacag tcgtgatgat ctcctggctc agcagctggc cttctcccac cagtgactcg
     9001 tcagtccggt ttgaacgaac agggacctgg agcaggtctg atgttggaaa gggtattgtc
     9061 ctagacaggt cgtagcattg ccgtgcgaga gtttcgttct ctggattgtg caggttgctt
     9121 cggatgtgca tcattctggg ccggagcccc tgcttgtctg catgcgcctt gagagcttcc
     9181 atatcgtctt caggggcggt taagcacacg gtcctgggtt ccgtgatggt tgagaggatg
     9241 gcctgcaagg gttggtaagc tgttcagaga tgagatgaga cggtcgggga tggagaacgt
     9301 acggttggga atctgcccag tatctcatgg acgtcgtcgt ggtttcgcag ggaaatttgc
     9361 agagtcctcg tcgatgatgg cgatgatgat gccgaagatg cctgtcccaa atctccaaag
     9421 gcaccgattg cgagagatag atggaggcct gccaccgcat gctgcaccaa ctcttgttcg
     9481 tctcttgaag ccgcggcgat gacagcggac aacagaccga tgcagtagcc ttggacccct
     9541 ccgcgttgga cgacgcttcg caggaaatcc gaatgtgaca ggccagcacc tctgatgaat
     9601 gagaggtact ggacaatgtg gatcgtggtt aggagaggca aggtgatgat gcctgacatg
     9661 tcctgctcaa gcacgtccga ctctccggtc tcgatccatt gcggaaagct tccgatggct
     9721 ttgctcgcga gctcaaggcg ggaaacgtct tgtctcgagg cggttaaggt ttgccatgtt
     9781 tctggtaagt tgacaattgc atccttcaag ggctcgaggc tggggtcctc cagcaatctg
     9841 gtccggatat aagaaaggtg ggtggatggc ggtgggctgc tttgtgggga gaatacggcc
     9901 gccgagaggg tcgtgttgga cggcatgagc gtcatggtaa ttcgaactgc gctctacagc
     9961 aaaccaaatg tagcggtgag aactgaacgc gtgttgagtt gttagagtct tgccttgcat
    10021 tattgtagat gagcaaaggg agggctgctt gccaaggacg gcgattctgg tgtgtgtgtg
    10081 tgtgtgtgtg tgtggtgtgt tgtggatttt cgccgaaata tcgaggactc ggacaattta
    10141 ggtggtagac cagggtgtcg gtccatatca ttctagtcct aggcaagttg acacgggtgg
    10201 gatacctcac agtttctaga aacatcaact tgccgggcta tcggtgcccc gagtctaagc
    10261 catatttcca gatcaaatca ttttcccctg gcgaacggtt ctgtacgtat tatctatcag
    10321 gagatgacat gtctagggtg acccatgaaa aaaccatatt tagatttgaa ccaatcctgt
    10381 tagctgcact cagaagatat ggatttacac tggttggatt taatactgct gcaccagcga
    10441 agctttggtc gtgttgatcg tccatcgatg ccccagagat cattctgaca gttcacacat
    10501 cttctctttc ccaattaacg acacaagaag tacagagagc aaagagtttg ctacgatgac
    10561 gaatgttttc atgtttaacc ccaatagcgg tattgtttgc cacgaaagag gaatctgtgc
    10621 ccgttgacgt tgtggaagca cgtgaatgtt tatttccctt ctcattgtgc tatgaacttc
    10681 agtgtcacaa aacgacatca tcgacaaaca ttgctatcta gggccctctc tttcacaagg
    10741 aaatcattca acattacact ccgtaaccat gtccgtccct tggcttcgtc tatctgctca
    10801 agtatccaac atccagccaa tacttgacat aagcatggag ggtggcatca tcgacagcgc
    10861 ccaggtcgcg cagcgtaccg gaccgcgtct tcgcgacgct tgtgtccagg accaccgatc
    10921 cacaggccac gggctggaac agatgcttga agaatgcgta gagcttcttg acgggaagct
    10981 tctcgtcgtc ctgctcggcg ccggcaacct gctcgagcca ctcctggaac ggcacggacg
    11041 gcttgaggtt cagctgcctg ccgaaggact ccatcaggtc gctccacggt tgacgtgtcg
    11101 ggttatccag gtgcagcgtg atggggagtg gctcgggcga gaaggcgatc tccgagatga
    11161 cggatgcggc atcgtcgaca gggatccagg aaagttccta cgacggaaag ttaatactct
    11221 ggggacttca cgtgggcggc ggggagaggg aggggaaatt caacgactac ttacaccgga
    11281 tagctgaggc aacgaaccaa ggctctgagc agacttgagc agcatcggga tctgctcgtt
    11341 ggtgttccac acacccgtcc ccttggcgcc ggtgatctgg ccgcagcgga ccgaggtgac
    11401 ctcgagctgg ccggcatacg cctccgccgc ccgctcgaca atcttctcgc acgcgagctt
    11461 gccgtcggcg tagccgatcc cgcacgcggc ctcctcgggg gagacgggcg cctccgggat
    11521 cgccgacccg gggttgtcca gcccgatctt ggcgaccgcg gcgatggacg agacgaagac
    11581 cagccggcgc ttcgtccggc cgggcgcgtg ggcggcgaac tcgagcaggc tccggaggaa
    11641 ctggagctgg taccggaacg agcgcagcgg gatgaggtag ttcatcggcc aggcggcgtg
    11701 gacgacgtgc gtcaccttct cctgcatggc ggcgtagacc atgggcatca gacccagcct
    11761 ctcggcggtg ggatcgacct cgagagtggc gatcttggac cactcttcct cggcgaggtc
    11821 cagccctcgc gccttgaggg ttctgcggtc gaacggtcct ccgccggggg gaggcggcgc
    11881 gttggcgccc ttctccttgc ggatgaggca gatgatgcgc ctgacctgcg gtctccgggc
    11941 gaggtcggcg acgcagtggg agccgagact ccccgagctg cccgtcaaga gaacgacggc
    12001 gtggtcggcg ctgctgggtt gcttctcctc ctccgtgctg gccccgccga ggctgtactg
    12061 atcgacgagc tccttcacct ccttgacagc gtctccggac gagtcagtct cgccgccgcc
    12121 gccgctcgac cgttgcagaa tcgcggccgc catctcccgc accgaagggt tgcggtatat
    12181 gaactgggac gggatcatct tggccacgtc cacgtccttc agaccctccg tcttggacgc
    12241 cgcggcaatg agaactctcc gcagctggag ggcctgcagg gagtcgacgc ccaggtcgaa
    12301 gaggctgtcg tcgacggccc acgccgagat gggcgtctgg agccgcaggt gctcgtgcac
    12361 aagagccttg atgttctcct cgaggttgtc gaggtccagc ggcccgacgc tctcggtggc
    12421 ggcctgcacc agcctctcgt agacggcctt gatctcctcg tcgaacaggg cgtacgtctc
    12481 cttgcgggcg atggacccct tgtcggtccg cgggacgacc ttgccgccgg gcacgacgat
    12541 gatggcgtcc ggcgagggga cgcgcgccga ggcgtccatc ttctgcccgg ccgccgtgac
    12601 gatgggccag atcgtctcgc ggaacgcctc ctcgtccccg ggcgcgagca gcggctcccg
    12661 cggctcgacg atgacgccga ggttgaactg gttctcgccg aacgcgacgg ccgacttgac
    12721 cgcgggcgcc tcgctcagca tcgtctcgag gatcaggggg tcggccttct cccccgtcgc
    12781 cagcacgatg acgtcgtcgt cgcggccgac agccgcgaag tcggtctcgg gatactgctc
    12841 gttccggacg agctggtcgg cgatctcgat gccctcgccg tcgccaaagg ggaacacggt
    12901 gagccggaac ctcctctcgc cgtcccgggg ctcgagctcg gccaccgtga acttcatgtc
    12961 gttccggagc cggaagtact tccagtcgta cgagtccgtg ggcgcgaaga tcagggacag
    13021 gtggcccgcc tcggtggtcc cgtagaagtt gaggagcttg acgccgcccg ccgccagcct
    13081 gtcgccgacg ccggcgccca gcgcggcgcc cccggtgccc acgaagtcca tgtgcgccag
    13141 cgccttgatg ccctcgtcgt cggggaggtc gcagatggcg tcgaggagga acggcaccgt
    13201 catcatggac ctggccttgg tcttcttcac gagctcgatg atggacacgg cgttcgggat
    13261 cccgtcgctc acggggtaca gcgtcggctt gcccgccgac agggagaggc ccggggcgac
    13321 gaggccgaag ccgtggaaga ggggcagggt cgagaggttg aggccctgcg cctgctcctc
    13381 cgtgtcgaag ccgtggcagt tgagggcgaa gagcagctgg cggtgcgtga gggggatggg
    13441 cttcgggaat cccgtcgtgc cggaggagtg gaggagcagg acgacgctgt ttctgtcctc
    13501 ggggctctcg aaggcgggca cggaggaggc atccgcgtgc ggctcgtaga aggcgtcgta
    13561 gcggttagcg atgtgagtcg agatgccctt ggatgcgaga gccgccagtg ctggcttcgc
    13621 aggctcgctg aggcgttgag acacgatgaa ggagccggcc gaggttgcct ccatcagcgc
    13681 attgatggca gccggcggaa gacgcgcaga gagaacgagg ggcttccaag aacgtgttag
    13741 tcacggttgt catgactgag gacgggaaaa acatcagaga ggccatggaa gggaggaggt
    13801 tctggactta cagggacgcc gatgctcatg agggcgaact cgtggatcac caacccgaca
    13861 tcgctctcca taaacagggc cacaggcgcc atcttcgttg ccgcggagtc ccccccagac
    13921 gcctgacgca gtggcagatt ctgcttgagc cacgccgcac atcttgatac ggcgaccttg
    13981 aactcggcat gggtgactgt gtcgaagggg tcggtgggct ttgcctggac gcagaacggg
    14041 tgggaggggt tgtgggtggc gttgaagtcg atgagctcag ggatcgagtg gagatggccg
    14101 tccagcctct tgtctgactc gaagttgacc gccggtctct tgaagggccg gatgctaccc
    14161 gccgccgcct tgggctcagt aatggcactc atgattgtga ttgttgggtt gtaatagttt
    14221 gaggactgat agagcaatca ggggttcagg aagaaacagg ctacacgaaa aagggaacac
    14281 tggttacaat aagctccaag tagtcaaccg atctgatccg atccgttctt gatgctttga
    14341 gagcagtacg agtgctcact cggggtgttt cgctgccccc cccctccccc ctcctcccac
    14401 ccccccgtcg gcgaatatca agactcgggc aaatcggggc attggcatct ctcctcggtt
    14461 agtttgggct cgactgctct ctcttttagt cggcaagact ttgggagact tttaacacgg
    14521 gtttgctctt tgtttttcct caactcgtga gtttaacttt cccctcaaca gttgtggcga
    14581 gttatcaaat tgcaactcct cttccattgc tcccccccct ttgttccaat atcaagcttc
    14641 tgtctctccc ataagctggc caacacacaa ccgcaaccga gatcgccatg gcaccttcat
    14701 catccaaagc cactgcaaag gaaagccccg agaagaaacc cctgatcgga gaggcgccac
    14761 catacaaacc cccaacaaag ggcttcctgt ccatcctgcc ggcgtcatgg gtcccctacg
    14821 ccgagctcac gcgcatccac cagccgcacg gcatctacat gatctacttc ccgcacctcg
    14881 tcggcctcgc ctacgccgcc tccgtccagc aggctgacct ggcaatgccc ccctccgagc
    14941 tggcctaccg cgccgccgtc atgctcggct ggaccgtgtt ctggcggagc ggcatctgcg
    15001 tgtggaacga caacatcgac caggactttg accgcaagac ggcgcggtgc cggaaccggc
    15061 ccatcgcgcg cggcgccatc tcgacggccc agggccacgt ctttgccctc gtcctgaacc
    15121 tcatcgcctt cgcctggctg cgtctgctgc ctcgggagtg cacgctggtc gcgctcggct
    15181 cgacggtgct cggcatgatc tacccgttcg gcaagcgatt cacctactac ccgcaggtca
    15241 tcctcggctc gaccctcggg tcgaccgtcg ccctgtccgc ctactccgtc ggcctgccgg
    15301 ccgtctcccc gccgtacctc ggcacgacgg cgtgcctcgc ggccgcggtc ctgctgctcg
    15361 tcgtcttcta cgacaccgtc tacgcccgcc aggacaccgc cgacgacctc aagtcgggcg
    15421 tcaagggcat ggcggtgcgc ttcagggacc acatcgaggg cctcctcgcc gtcctcgccg
    15481 tctccatcgc ggcgctgctg accaccgccg gcgtcctgat ggaggcgcag cagtactact
    15541 acgtgttttc cgtcggcggg ctcaccatgg gcctcatctc gctggtggcc ctcacgcatt
    15601 gggatcttct gcccagctgg gccggctcct cgggttggtg ctacgctctc gccatcgcca
    15661 acctcatcgg cggcatggcc tcgcaatacg ttctcaaagg cgctgcttga
//
