BGC0002813: phorbactazole A biosynthetic gene cluster from Acanthopleuribacter pedis KCTC 12899
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 395,107 - 543,466 nt. (total: 148,360 nt).
This entry is originally from NCBI GenBank JAFREP010000003.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0002813
Short description phorbactazole A biosynthetic gene cluster from Acanthopleuribacter pedis KCTC 12899
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Trans-AT type I)
  • NRPS (Type I)
Loci
JAFREP010000003.1
413747 - 538634
via Correlation of genomic and metabolomic data
Compounds
  • phorbactazole A
  • phorbactazole B
  • phorbactazole C
  • phorbactazole D
  • phorbactazole E
  • phorbactazole F
Species Acanthopleuribacter pedis KCTC 12899 [taxonomy]
References
Chemical products information
phorbactazole A Evidence: NMR
Copy SMILES
C51H73N3O17
phorbactazole B Evidence: NMR
Copy SMILES
C50H72N2O16
phorbactazole C Evidence: NMR
Copy SMILES
C57H83N3O22
phorbactazole D Evidence: NMR
Copy SMILES
C56H82N2O21
phorbactazole E Evidence: NMR
Copy SMILES
C57H81N3O21
phorbactazole F Evidence: NMR
Copy SMILES
C56H77N3O20
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • J3U88_04895
  • MBO1317789.1
 413747 - 415066 (-) glycosyltransferase family 1 protein
    copy AA seq
    copy Nt seq
    • J3U88_04900
    • MBO1317790.1
    • fabD
    		 415107 - 416249 (-) ACP S-malonyltransferase
      copy AA seq
      copy Nt seq
      • J3U88_04905
      • MBO1317791.1
      		 417628 - 418608 (+) hypothetical protein
        copy AA seq
        copy Nt seq
        • J3U88_04910
        • MBO1317792.1
        		 418907 - 420025 (-) hypothetical protein
          copy AA seq
          copy Nt seq
          • J3U88_04915
          • MBO1317793.1
          		 420031 - 421533 (-) AAA family ATPase
            copy AA seq
            copy Nt seq
            • J3U88_04920
            • MBO1317794.1
            		 421659 - 423791 (-) ABC transporter ATP-binding protein
              copy AA seq
              copy Nt seq
              • J3U88_04925
              • MBO1317795.1
              		 424304 - 469606 (+) amino acid adenylation domain-containing protein
                copy AA seq
                copy Nt seq
                • J3U88_04930
                • MBO1317796.1
                		 469603 - 478347 (+) SDR family NAD(P)-dependent oxidoreductase
                  copy AA seq
                  copy Nt seq
                  • J3U88_04935
                  • MBO1317797.1
                  		 478344 - 491099 (+) amino acid adenylation domain-containing protein
                    copy AA seq
                    copy Nt seq
                    • J3U88_04940
                    • MBO1317798.1
                    		 491108 - 506137 (+) SDR family NAD(P)-dependent oxidoreductase
                      copy AA seq
                      copy Nt seq
                      • J3U88_04945
                      • MBO1317799.1
                      		 506134 - 535593 (+) SDR family NAD(P)-dependent oxidoreductase
                        copy AA seq
                        copy Nt seq
                        • J3U88_04950
                        • MBO1317800.1
                        		 535617 - 536768 (+) LLM class flavin-dependent oxidoreductase
                          copy AA seq
                          copy Nt seq
                          • J3U88_04955
                          • MBO1317801.1
                          		 536835 - 538634 (+) hypothetical protein
                            copy AA seq
                            copy Nt seq
                            Biosynthesis information

                            No biosynthesis information available for this record.

                            Annotation changelog

                            Entry version: 1

                            Date
                            Changes
                            Submitters
                            Reviewers
                            2023-11-15
                            Created entry for phorbactazole BGC.
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                            2023-11-15
                            Reviewed and approved entry.
                            • (ID: C62OJVVH7XOTOTFZSJT727YU)
                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                            Similar known clusters from MIBiG 4.0
                            Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                            Detailed help and explanations are available here.

                            Click on reference genes to show details of similarities to genes within the current region.
                            Double click on a reference drawing to reverse the display of the genes.

                            Click on an accession to open that entry in the MIBiG database.


                            Location:

                            Identifier
                            Identity
                            Coverage
                            Detailed domain annotation
                            Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
                            A domain glossary is available here, and an explanation of the visualisation is available here.
                            Selected features only
                            Show module domains