BGC0002816: terpenomycin biosynthetic gene cluster from Nocardia terpenica AUSMDU00012715
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Location: 4,633,632 - 4,752,882 nt. (total: 119,251 nt).
This entry is originally from NCBI GenBank CP046173.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
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KnownClusterBlast
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0002816
Short description terpenomycin biosynthetic gene cluster from Nocardia terpenica AUSMDU00012715
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Modular type I)
Loci
CP046173.1
4647226 - 4733531
via Knock-out studies
Compounds
  • terpenomycin
Species Nocardia terpenica AUSMDU00012715 [taxonomy]
References
Chemical products information
terpenomycin Evidence: NMR, MS/MS
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C53H82O14
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • F6W96_21250
  • QIS20444.1
 4647226 - 4647894 (+) SAM-dependent methyltransferase
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    • F6W96_21255
    • QIS20445.1
    		 4647906 - 4649996 (-) AfsR family transcriptional regulator
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      • F6W96_21260
      • QIS20446.1
      		 4650203 - 4651300 (-) HAD-IIIC family phosphatase
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        • F6W96_21265
        • QIS20447.1
        		 4651322 - 4652431 (-) acyl-CoA dehydrogenase
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          • F6W96_21270
          • QIS24350.1
          		 4652428 - 4652691 (-) acyl carrier protein
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            • F6W96_21275
            • QIS20448.1
            		 4652731 - 4653603 (-) 3-hydroxyacyl-CoA dehydrogenase family protein
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              • F6W96_21280
              • QIS20449.1
              		 4653632 - 4659718 (-) SDR family NAD(P)-dependent oxidoreductase
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                • F6W96_21285
                • QIS20450.1
                		 4659744 - 4669841 (-) SDR family NAD(P)-dependent oxidoreductase
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                  • F6W96_21290
                  • QIS20451.1
                  		 4669858 - 4681464 (-) SDR family NAD(P)-dependent oxidoreductase
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                    • F6W96_21295
                    • QIS24351.1
                    		 4681457 - 4685296 (-) SDR family NAD(P)-dependent oxidoreductase
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                      • F6W96_21300
                      • QIS20452.1
                      		 4685530 - 4696218 (-) SDR family NAD(P)-dependent oxidoreductase
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                        • F6W96_21305
                        • QIS20453.1
                        		 4696300 - 4697334 (-) gfo/Idh/MocA family oxidoreductase
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                          • F6W96_21310
                          • QIS20454.1
                          		 4697331 - 4698803 (-) NDP-hexose 2,3-dehydratase
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                            • F6W96_21315
                            • QIS20455.1
                            		 4698834 - 4700087 (-) glycosyltransferase
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                              • F6W96_21320
                              • QIS20456.1
                              		 4700242 - 4713951 (-) SDR family NAD(P)-dependent oxidoreductase
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                                • F6W96_21325
                                • QIS20457.1
                                		 4713951 - 4719488 (-) SDR family NAD(P)-dependent oxidoreductase
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                                  • F6W96_21330
                                  • QIS20458.1
                                  		 4719488 - 4732882 (-) SDR family NAD(P)-dependent oxidoreductase
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                                    • F6W96_21335
                                    • QIS20459.1
                                    • rfbC
                                    		 4732968 - 4733531 (-) dTDP-4-dehydrorhamnose 3,5-epimerase
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                                      Biosynthesis information

                                      No biosynthesis information available for this record.

                                      Annotation changelog

                                      Entry version: 1

                                      Date
                                      Changes
                                      Submitters
                                      Reviewers
                                      2023-11-14
                                      Add new entry for terpenomycin.
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                      2023-11-14
                                      Reviewed and approved.
                                      • (ID: 55JKZ6YQD2AUFWZ45WR2BXVC)
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                      2023-11-21
                                      Reviewed and approved.
                                      • (ID: C62OJVVH7XOTOTFZSJT727YU)
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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                                      Detailed domain annotation
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