BGC0002826: closoxazole A biosynthetic gene cluster from Clostridium cavendishii DSM 21758
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 98,901 - 104,384 nt. (total: 5,484 nt).
This entry is originally from NCBI GenBank FQZB01000008.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002826
Short description closoxazole A biosynthetic gene cluster from Clostridium cavendishii DSM 21758
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • other (other)
Loci
FQZB01000008.1
98901 - 104384
via Knock-out studies, Heterologous expression
Compounds
  • closoxazole A
  • closoxazole B
Species Clostridium cavendishii DSM 21758 [taxonomy]
References
Chemical products information
closoxazole A Evidence: NMR
Copy SMILES
C21H16N3O6
closoxazole B Evidence: MS/MS
Copy SMILES
C21H16N3O5
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Comment Extra
  • SAMN02745163_01864
  • SHJ39796.1
 98973 - 100178 (+) phenylacetate-CoA ligase
    In RefSeq entry 'NZ_FQZB01000008.1', gene starts 72 nt earlier (98901..100178).
    copy AA seq
    copy Nt seq
    • SAMN02745163_01865
    • SHJ39836.1
    		 100246 - 101373 (+) 3-amino-4-hydroxybenzoic acid synthase
      copy AA seq
      copy Nt seq
      • SAMN02745163_01866
      • SHJ39872.1
      		 101410 - 102738 (+) phenylacetate-CoA ligase
        copy AA seq
        copy Nt seq
        • SAMN02745163_01867
        • SHJ39914.1
        		 102786 - 103553 (+) hypothetical protein
          copy AA seq
          copy Nt seq
          • SAMN02745163_01868
          • SHJ39949.1
          		 103560 - 104384 (+) 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase
            copy AA seq
            copy Nt seq
            Biosynthesis information

            No biosynthesis information available for this record.

            Annotation changelog

            Entry version: 1

            Date
            Changes
            Submitters
            Reviewers
            2023-12-06
            Created entry.
            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
            • (ID: C62OJVVH7XOTOTFZSJT727YU)
            • (ID: DKBFG3K6XTYSVEQEQVCFZBWY)
            Similar known clusters from MIBiG 4.0
            Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
            Detailed help and explanations are available here.

            Click on reference genes to show details of similarities to genes within the current region.
            Double click on a reference drawing to reverse the display of the genes.

            Click on an accession to open that entry in the MIBiG database.


            Location:

            Identifier
            Identity
            Coverage