BGC0002892: kistamicin biosynthetic gene cluster from Actinomadura parvosata subsp. kistnae
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Location: 1,780,967 - 1,852,209 nt. (total: 71,243 nt).
This entry is originally from NCBI GenBank CP017717.1.

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core biosynthetic genes
additional biosynthetic genes
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resistance
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002892
Short description kistamicin biosynthetic gene cluster from Actinomadura parvosata subsp. kistnae
Status Quality: questionable
The quality level of this entry.

Status: pending
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Remarks "Nonomuraea sp. ATCC55076"
Biosynthetic class(es)
  • NRPS (Type I)
Loci
CP017717.1
1780967 - 1852209
via Gene expression correlated with compound production [1], [2]
Compounds
  • kistamicin
Species Actinomadura parvosata subsp. kistnae [taxonomy]
References
Chemical products information
kistamicin [synonyms: kistamycin] Evidence:
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C61H51Cl1N8O15
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BKM31_07955
  • AQZ61417.1
 1782026 - 1782319 (+) hypothetical protein
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    • BKM31_07960
    • AQZ61418.1
    		 1782320 - 1783009 (-) NAD(P)H dehydrogenase
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      • BKM31_07965
      • AQZ61419.1
      		 1783104 - 1783556 (+) MarR family transcriptional regulator
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        • BKM31_07970
        • AQZ61420.1
        		 1783574 - 1784461 (-) aminoglycoside phosphotransferase
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          • BKM31_07975
          • AQZ70222.1
          		 1784775 - 1785410 (+) hypothetical protein
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            • BKM31_07980
            • AQZ70223.1
            		 1785500 - 1786669 (+) acyltransferase
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              • BKM31_07985
              • AQZ70224.1
              		 1786762 - 1787301 (+) hypothetical protein
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                • BKM31_07990
                • AQZ61421.1
                		 1787298 - 1787981 (+) DNA-binding response regulator
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                  • BKM31_07995
                  • AQZ61422.1
                  		 1787978 - 1789426 (+) two-component sensor histidine kinase
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                    • BKM31_08000
                    • AQZ61423.1
                    		 1789498 - 1791510 (+) hypothetical protein
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                      • BKM31_08005
                      • AQZ61424.1
                      		 1791575 - 1791832 (-) hypothetical protein
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                        • BKM31_08010
                        • AQZ61425.1
                        		 1791973 - 1792551 (-) TetR family transcriptional regulator
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                          • BKM31_08015
                          • AQZ61426.1
                          		 1792548 - 1793339 (-) retinol dehydrogenase
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                            • BKM31_08020
                            • AQZ70225.1
                            		 1793373 - 1794326 (-) hypothetical protein
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                              • BKM31_08025
                              • AQZ61427.1
                              		 1794453 - 1795121 (+) methyltransferase
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                                • BKM31_08030
                                • AQZ61428.1
                                		 1795134 - 1796462 (-) FAD-linked oxidase
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                                  • BKM31_08035
                                  • AQZ61429.1
                                  		 1796522 - 1797940 (+) GntR family transcriptional regulator
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                                    • BKM31_08040
                                    • AQZ61430.1
                                    		 1798031 - 1798696 (+) hypothetical protein
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                                      • BKM31_08045
                                      • AQZ61431.1
                                      		 1799087 - 1799575 (-) hypothetical protein
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                                        • BKM31_08050
                                        • AQZ61432.1
                                        		 1799596 - 1802586 (+) hypothetical protein
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                                          • BKM31_08055
                                          • AQZ61433.1
                                          		 1802654 - 1803745 (+) sugar ABC transporter substrate-binding protein
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                                            • BKM31_08060
                                            • AQZ61434.1
                                            		 1803745 - 1804515 (+) ABC transporter ATP-binding protein
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                                              • BKM31_08065
                                              		 1804529 - 1805518 (+) iron transporter
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                                                • BKM31_08070
                                                • AQZ61435.1
                                                		 1805620 - 1806972 (+) MFS transporter
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                                                  • BKM31_08075
                                                  • AQZ70226.1
                                                  		 1807126 - 1808454 (+) flavoprotein
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                                                    • BKM31_08080
                                                    • AQZ61436.1
                                                    		 1808514 - 1808852 (+) transcriptional regulator
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                                                      • BKM31_08085
                                                      • AQZ61437.1
                                                      		 1808857 - 1809228 (-) hypothetical protein
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                                                        • BKM31_08090
                                                        • AQZ61438.1
                                                        		 1809558 - 1810301 (+) short-chain dehydrogenase
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                                                          • BKM31_08095
                                                          • AQZ70227.1
                                                          		 1810436 - 1811305 (+) RNA polymerase subunit sigma-70
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                                                            • BKM31_08100
                                                            • AQZ61439.1
                                                            		 1811649 - 1812092 (-) MarR family transcriptional regulator
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                                                              • BKM31_08105
                                                              • AQZ61440.1
                                                              		 1812179 - 1813534 (+) MFS transporter
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                                                                • BKM31_08110
                                                                • AQZ61441.1
                                                                		 1813571 - 1813996 (+) cobalamin adenosyltransferase
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                                                                  • BKM31_08115
                                                                  • AQZ61442.1
                                                                  		 1814101 - 1814466 (-) hypothetical protein
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                                                                    • BKM31_08120
                                                                    • AQZ61443.1
                                                                    		 1814566 - 1815462 (-) LLM class F420-dependent oxidoreductase
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                                                                      • BKM31_08125
                                                                      • AQZ61444.1
                                                                      		 1815562 - 1816140 (+) TetR family transcriptional regulator
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                                                                        • BKM31_08130
                                                                        • AQZ61445.1
                                                                        		 1816185 - 1819526 (-) hypothetical protein
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                                                                          • BKM31_08135
                                                                          • AQZ61446.1
                                                                          		 1819767 - 1820768 (-) LysR family transcriptional regulator
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                                                                            • BKM31_08140
                                                                            • AQZ61447.1
                                                                            		 1820998 - 1822224 (+) MFS transporter
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                                                                              • BKM31_08145
                                                                              • AQZ61448.1
                                                                              		 1822355 - 1824409 (+) hypothetical protein
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                                                                                • BKM31_08150
                                                                                • AQZ70228.1
                                                                                		 1824375 - 1825259 (-) hypothetical protein
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                                                                                  • BKM31_08155
                                                                                  • AQZ61449.1
                                                                                  		 1825372 - 1825791 (+) hypothetical protein
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                                                                                    • BKM31_08160
                                                                                    • AQZ61450.1
                                                                                    		 1825844 - 1827559 (+) copper oxidase
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                                                                                      • BKM31_08165
                                                                                      • AQZ61451.1
                                                                                      		 1827713 - 1829806 (+) hypothetical protein
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                                                                                        • BKM31_08170
                                                                                        • AQZ61452.1
                                                                                        		 1829799 - 1831751 (+) hypothetical protein
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                                                                                          • BKM31_08175
                                                                                          • AQZ61453.1
                                                                                          		 1831862 - 1833637 (+) hypothetical protein
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                                                                                            • BKM31_08180
                                                                                            • AQZ61454.1
                                                                                            		 1833627 - 1833806 (+) hypothetical protein
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                                                                                              • BKM31_08185
                                                                                              • AQZ61455.1
                                                                                              		 1834058 - 1836799 (+) hypothetical protein
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                                                                                                • BKM31_08190
                                                                                                • AQZ61456.1
                                                                                                		 1836796 - 1838136 (+) hypothetical protein
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                                                                                                  • BKM31_08195
                                                                                                  • AQZ61457.1
                                                                                                  		 1838124 - 1839326 (+) hypothetical protein
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                                                                                                    • BKM31_08200
                                                                                                    • AQZ61458.1
                                                                                                    		 1839445 - 1840092 (-) GntR family transcriptional regulator
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                                                                                                      • BKM31_08205
                                                                                                      • AQZ61459.1
                                                                                                      		 1840194 - 1840775 (+) kinase inhibitor
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                                                                                                        • BKM31_08210
                                                                                                        • AQZ61460.1
                                                                                                        		 1840772 - 1841176 (+) cupin
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                                                                                                          • BKM31_08215
                                                                                                          • AQZ61461.1
                                                                                                          		 1841216 - 1841950 (+) TetR family transcriptional regulator
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                                                                                                            • BKM31_08220
                                                                                                            • AQZ61462.1
                                                                                                            		 1842055 - 1842912 (-) NAD(P)-dependent oxidoreductase
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                                                                                                              • BKM31_08225
                                                                                                              • AQZ61463.1
                                                                                                              		 1842983 - 1843789 (-) NADPH-dependent ferric siderophore reductase
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                                                                                                                • BKM31_08230
                                                                                                                • AQZ61464.1
                                                                                                                		 1843803 - 1844711 (-) phthalate 4,5-dioxygenase
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                                                                                                                  • BKM31_08235
                                                                                                                  • AQZ61465.1
                                                                                                                  		 1844727 - 1845371 (-) flavin-nucleotide-binding protein
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                                                                                                                    • BKM31_08240
                                                                                                                    • AQZ61466.1
                                                                                                                    		 1845442 - 1846056 (+) TetR family transcriptional regulator
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                                                                                                                      • BKM31_08245
                                                                                                                      • AQZ61467.1
                                                                                                                      		 1846067 - 1847317 (-) cytochrome
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                                                                                                                        • BKM31_08250
                                                                                                                        • AQZ61468.1
                                                                                                                        		 1847400 - 1848317 (-) AraC family transcriptional regulator
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                                                                                                                          • BKM31_08255
                                                                                                                          • AQZ61469.1
                                                                                                                          		 1848400 - 1849245 (+) NAD(P)-dependent oxidoreductase
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                                                                                                                            • BKM31_08260
                                                                                                                            • AQZ61470.1
                                                                                                                            		 1849405 - 1850532 (+) hypothetical protein
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                                                                                                                              • BKM31_08265
                                                                                                                              • AQZ70229.1
                                                                                                                              		 1850549 - 1851706 (-) rod shape-determining protein RodA
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                                                                                                                                Biosynthesis information

                                                                                                                                No biosynthesis information available for this record.

                                                                                                                                Annotation changelog

                                                                                                                                Entry version: 1

                                                                                                                                Date
                                                                                                                                Changes
                                                                                                                                Submitters
                                                                                                                                Reviewers
                                                                                                                                2024-07-23
                                                                                                                                MIBiG v4 annotathon
                                                                                                                                • (ID: TVYWRCMOBR5VOOLSE2IIZG7H)
                                                                                                                                • (ID: W3QOK3QPXTRJDCB4DPJ3LOBQ)
                                                                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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