BGC0002929: Dictyodene A biosynthetic gene cluster from Dictyostelium discoideum AX4
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Location: 479,181 - 526,804 nt. (total: 47,624 nt).
This entry is originally from NCBI GenBank CM000151.3.

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
NRPS/PKS domains
General information about the BGC

MIBiG accession | BGC0002929
Short description | Dictyodene A biosynthetic gene cluster from Dictyostelium discoideum AX4
Status | Quality: high The quality level of this entry. Status: pending The status of this entry. Completeness: unknown Whether the entry covers everything needed for the pathway producing the compound(s)

Remarks "Authors used strain AX2, but the identification of this PKS gene is based on genetic sequence of AX4, as that is the only available. Also, they directly reference the works done on strain AX4 when discussing DNA and RNA sequence data. "
Biosynthetic class(es)

- PKS (Type I)

Loci
CM000151.3
499181 - 506804
via Knock-out studies [1], Gene expression correlated with compound production [1]
Compounds

- Dictyodene A
- Dictyodene B

Species Dictyostelium discoideum AX4 [taxonomy]
References

- [1] Yellow polyketide pigment suppresses premature hatching in social amoeba. Günther, M et al., Proceedings of the National Academy of Sciences (2022) DOI:10.1073/pnas.2116122119

Chemical products information
Dictyodene A Evidence: NMR [1]
Copy SMILES
C19H24O3
Dictyodene B Evidence: NMR [1]
Copy SMILES
C19H24O3
List of genes involved in compound(s) production

Identifiers | Position | Product | Functions | Evidence | Extra
--- | --- | --- | --- | --- | ---
DDB_G0271520 EAL71624.1 pks5 | 499181 - 506804 (+) | hypothetical protein |  |  | copy AA seq copy Nt seq

Biosynthesis information

No biosynthesis information available for this record.

Annotation changelog

#### Entry version: 1

Date
Changes
Submitters
Reviewers
2024-05-17
MIBiG v4 annotathon

- (ID: XHGUMDYTPFJLKYNSR4GE4XPC)
- (ID: SKC4XYF2AQLXBPOFDVNEXQZ2)

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

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Detailed domain annotation
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