BGC0002964: 25-hydroxy peucemycin biosynthetic gene cluster from Streptomyces peucetius ATCC 27952
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Location: 1,767,171 - 1,835,426 nt. (total: 68,256 nt).
This entry is originally from NCBI GenBank CP022438.

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General information about the BGC

MIBiG accession | BGC0002964
Short description | 25-hydroxy peucemycin biosynthetic gene cluster from Streptomyces peucetius ATCC 27952
Status | Quality: high The quality level of this entry. Status: pending The status of this entry. Completeness: complete Whether the entry covers everything needed for the pathway producing the compound(s)

Biosynthetic class(es)

- PKS (Type I)

Loci
CP022438
1770802 - 1821906
via Knock-out studies [1], Correlation of genomic and metabolomic data [1]
Compounds

- 25-hydroxy peucemycin

Species Streptomyces peucetius ATCC 27952 [taxonomy]
References

- [1] Biosynthetic pathway of peucemycin and identification of its derivative from Streptomyces peucetius. Magar, R et al., Applied Microbiology and Biotechnology (2023) DOI:10.1007/s00253-023-12385-8

Chemical products information
25-hydroxy peucemycin Evidence: Mass spectrometry [1]
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List of genes involved in compound(s) production

Identifiers | Position | Product | Functions | Evidence | Extra
--- | --- | --- | --- | --- | ---
CGZ69_08235 ATW52507.1 | 1770802 - 1771308 (-) | flavin reductase |  |  | copy AA seq copy Nt seq
CGZ69_08240 ATW47929.1 | 1771908 - 1772846 (-) | hypothetical protein |  |  | copy AA seq copy Nt seq
CGZ69_08245 ATW47930.1 | 1773094 - 1774203 (-) | hypothetical protein |  |  | copy AA seq copy Nt seq
CGZ69_08250 ATW47931.1 | 1774266 - 1775549 (-) | cytochrome P450 |  |  | copy AA seq copy Nt seq
CGZ69_08255 ATW52508.1 | 1775531 - 1776646 (-) | cytochrome P450 |  |  | copy AA seq copy Nt seq
CGZ69_08260 ATW47932.1 | 1776850 - 1777386 (-) | linA-like protein |  |  | copy AA seq copy Nt seq
CGZ69_08265 ATW47933.1 ccrA | 1777473 - 1778717 (-) | crotonyl-CoA carboxylase/reductase |  |  | copy AA seq copy Nt seq
CGZ69_08270 ATW47934.1 | 1778885 - 1779685 (-) | thioesterase |  |  | copy AA seq copy Nt seq
CGZ69_08275 | 1779692 - 1783685 (-) | beta-ketoacyl synthase |  |  | copy AA seq copy Nt seq
CGZ69_08280 | 1783678 - 1787113 (-) | beta-ketoacyl synthase |  |  | copy AA seq copy Nt seq
CGZ69_08285 ATW47935.1 | 1787171 - 1790572 (-) | hypothetical protein |  |  | copy AA seq copy Nt seq
CGZ69_08290 ATW47936.1 | 1790593 - 1801428 (-) | beta-ketoacyl synthase |  |  | copy AA seq copy Nt seq
CGZ69_08295 ATW47937.1 | 1801480 - 1815426 (-) | beta-ketoacyl synthase |  |  | copy AA seq copy Nt seq
CGZ69_08300 ATW47938.1 | 1816141 - 1817463 (+) | Hydroxylase | Hydroxylation | MITE0000147 [1] | copy AA seq copy Nt seq
CGZ69_08305 ATW47939.1 | 1817460 - 1818497 (+) | hypothetical protein |  |  | copy AA seq copy Nt seq
CGZ69_08310 ATW47940.1 | 1818782 - 1819390 (+) | TetR family transcriptional regulator |  |  | copy AA seq copy Nt seq
CGZ69_08315 ATW47941.1 | 1819636 - 1821906 (+) | Fe-S oxidoreductase |  |  | copy AA seq copy Nt seq

Biosynthesis information

No biosynthesis information available for this record.

Annotation changelog

#### Entry version: 1

Date
Changes
Submitters
Reviewers
2024-07-23
MIBiG v4 annotathon

- (ID: H5XARBFTJ7BRAHK5RG5DH2DC)

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

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