MIBiG Protein Description MIBiG Cluster MiBiG Product % ID % Coverage BLAST Score E-value
OEI75232.1 DNA-binding_response_regulator BGC0002977.1 NRPS:Type I+PKS:Type I 100.0 100.0 476.0 4.64e-173
OEI76711.1 DNA-binding_response_regulator BGC0002977.1 NRPS:Type I+PKS:Type I 53.0 99.6 245.0 5.75e-82
OEI74699.1 DNA-binding_response_regulator BGC0002977.1 NRPS:Type I+PKS:Type I 45.0 96.7 187.0 4.74e-59
ABI75119.1 transcriptional_regulator_OmpR_family BGC0000188.5 other:other 43.0 98.3 186.0 2.45e-58
OEI73917.1 DNA-binding_response_regulator BGC0002977.1 NRPS:Type I+PKS:Type I 42.0 95.8 184.0 3.75e-58
EKB09395.1 hypothetical_protein BGC0003104.1 ribosomal:RiPP:Lanthipeptide 42.0 97.1 182.0 3.11e-57
AAD21216.2 BacR BGC0000310.5 NRPS:Type I 45.0 95.4 178.0 1.85e-55
CAH60130.1 putative_two-component_response_regulator BGC0000700.5 saccharide 41.0 97.5 176.0 6.59e-55
OEI76576.1 DNA-binding_response_regulator BGC0002977.1 NRPS:Type I+PKS:Type I 41.0 97.1 176.0 7.56e-55
MUL41494.1 response_regulator_transcription_factor BGC0002045.3 PKS:Type II 41.0 95.4 174.0 3.21e-54
OEI72873.1 DNA-binding_response_regulator BGC0002977.1 NRPS:Type I+PKS:Type I 40.0 97.1 172.0 2.65e-53
BAQ25486.1 two-component_system_response_regulator BGC0001288.5 PKS 42.0 97.5 170.0 2.13e-52
KON97026.1 PhoP_family_transcriptional_regulator BGC0002122.2 NRPS:Type I 40.0 97.1 170.0 2.93e-52
QCT05734.1 Tri1 BGC0001983.3 other:other 42.0 97.9 167.0 1.46e-51
AEE65494.1 response_regulator BGC0000223.5 PKS:Type II 37.0 95.4 166.0 9.31e-51
ALJ99879.1 FlsR3 BGC0001904.2 PKS:Type II aromatic 37.0 95.4 165.0 1.32e-50
EDY47143.1 two-component_system_response_regulator BGC0000845.5 other:non-nrp beta-lactam 40.0 95.8 166.0 1.5e-50
CAJ34389.1 putative_response_regulator BGC0000445.5 NRPS:Type I 40.0 95.8 164.0 2.63e-50
ABB69091.1 hypothetical_protein BGC0000260.3 PKS 40.0 97.1 164.0 7.2e-50
AFI57015.1 QmnRg3 BGC0000133.5 PKS 40.0 97.1 162.0 2.42e-49
ADM69285.1 transcriptional_response_regulator BGC0001727.3 ribosomal:RiPP 40.0 98.8 162.0 2.8e-49
NII05595.1 heavy_metal_response_regulator_transcription_factor BGC0003005.1 NRPS:Type I 40.0 98.8 160.0 1.15e-48
CAF31457.2 putative_two-component_system_response_regulator BGC0000696.5 saccharide 37.0 97.1 159.0 2.51e-48
ACN38369.1 putative_two-component_system_response_regulator BGC0000714.5 saccharide 37.0 97.1 159.0 2.51e-48
ARV75734.1 putative_two-component_system_response_regulator BGC0001603.3 saccharide 37.0 97.1 159.0 2.51e-48
KON97034.1 DNA-binding_protein BGC0002122.2 NRPS:Type I 40.0 97.1 159.0 5.61e-48
CAB60254.1 MrsR2_protein BGC0000527.5 ribosomal:RiPP:Lanthipeptide 38.0 99.6 158.0 1.29e-47
AAS79471.1 putative_two-component_system_response_regulator BGC0000035.5 PKS 39.0 95.4 156.0 5.17e-47
AEG64695.1 response_regulator BGC0000379.5 NRPS:Type I 39.0 95.8 155.0 9.46e-47
CAB93669.1 RumR_protein BGC0000545.5 ribosomal:RiPP:Lanthipeptide 41.0 99.6 155.0 1.19e-46
AQZ61421.1 DNA-binding_response_regulator BGC0002892.1 NRPS:Type I 34.0 95.4 154.0 2.83e-46
QKW60381.1 response_regulator_transcription_factor BGC0002288.2 NRPS:Type I 37.0 98.8 153.0 7.07e-46
OEI75709.1 DNA-binding_response_regulator BGC0002977.1 NRPS:Type I+PKS:Type I 38.0 96.7 153.0 1.02e-45
AGU42430.1 Cmm22 BGC0000842.5 other:non-nrp beta-lactam 36.0 96.7 152.0 2.24e-45
OEI75686.1 DNA-binding_response_regulator BGC0002977.1 NRPS:Type I+PKS:Type I 36.0 97.5 149.0 1.68e-44
CCH32754.1 Transcriptional_regulator BGC0002070.3 PKS 38.0 95.4 140.0 1.04e-40
WP_078621122.1 response_regulator_transcription_factor BGC0002000.4 PKS 38.0 96.7 140.0 2.1e-40
POM23776.1 Transcriptional_regulatory_protein_SrrA BGC0002369.2 PKS 39.0 95.4 139.0 3.08e-40
OKI81334.1 transcriptional_regulator BGC0002478.3 PKS 36.0 97.9 138.0 7.18e-40
WP_002554192.1 heavy_metal_response_regulator_transcription_factor BGC0002571.2 NRPS:Type I 38.0 96.7 137.0 1.15e-39
ABO65653.1 Subtilin_biosynthesis_regulatory_protein_SpaR BGC0000515.4 ribosomal:RiPP:Lanthipeptide 38.0 96.2 137.0 1.25e-39
OEI75846.1 DNA-binding_response_regulator BGC0002977.1 NRPS:Type I+PKS:Type I 36.0 99.6 136.0 2.84e-39
QDG00834.1 two-component_system_response_regulator BGC0002028.4 PKS 37.0 97.1 139.0 3.31e-39
CAK15802.1 putative_DNA-binding_response_regulator,_OmpR_family BGC0000344.5 NRPS:Type I 38.0 87.9 134.0 9.76e-39
ADB02841.1 AzicR3 BGC0000202.5 PKS 36.0 99.6 134.0 1.8e-38
AAX57187.2 atypical_response_regulator BGC0000201.5 PKS+saccharide:hybrid/tailoring 36.0 95.4 134.0 2.57e-38
AGO50631.1 positive_regulation_regulator BGC0000229.5 PKS:Type II+saccharide:hybrid/tailoring 34.0 95.8 134.0 3.05e-38
BAJ07866.1 putative_repressor-response_regulator BGC0000232.5 PKS 34.0 95.8 134.0 3.39e-38
UYO79789.1 BalReg1 BGC0003038.1 PKS:Type II aromatic 34.0 95.4 133.0 3.96e-38
ARO44672.1 positive_regulation_regulator BGC0001769.5 PKS 35.0 96.7 134.0 4.85e-38
MBW8699708.1 Transcriptional_regulatory_protein_YycF BGC0002140.2 PKS 35.0 96.7 134.0 4.85e-38
AEK64499.1 EtnR BGC0000506.4 ribosomal:RiPP:Lanthipeptide 37.0 98.8 132.0 5.59e-38
BAV17023.1 putative_transcriptional_regulator BGC0001384.5 PKS 35.0 96.7 132.0 1.57e-37
AHW57766.1 PgaR1 BGC0000262.5 PKS:Type II+saccharide:hybrid/tailoring 36.0 97.1 132.0 2.39e-37
AAB91594.1 SpaR BGC0000559.4 ribosomal:RiPP:Lanthipeptide 37.0 98.8 130.0 3.11e-37
WP_237282926.1 response_regulator_transcription_factor BGC0001596.3 PKS:Type II aromatic 36.0 96.2 130.0 5.53e-37
BBA97247.1 putative_two-component_system_response_regulator BGC0002383.3 PKS 32.0 95.4 129.0 1.16e-36
AOT85874.1 response_regulator BGC0001789.3 ribosomal:RiPP 35.0 98.8 129.0 1.19e-36
QDG00829.1 two-component_system_response_regulator BGC0002028.4 PKS 35.0 96.7 130.0 2.09e-36
BAG71485.1 response_regulator BGC0000536.3 ribosomal:RiPP:Lanthipeptide 34.0 96.2 128.0 3.01e-36
TRO56970.1 response_regulator_transcription_factor BGC0002361.3 PKS+saccharide 33.0 95.4 129.0 3.72e-36
ABA00873.1 NsuR BGC0000537.3 ribosomal:RiPP:Lanthipeptide 35.0 100.8 128.0 4.7e-36
EFV97036.1 nisin_biosynthesis_regulatory_protein_NisR BGC0003095.1 ribosomal:RiPP:Lanthipeptide 36.0 98.8 128.0 4.7e-36
BAC79018.1 repressor-response_regulator BGC0000245.5 PKS 34.0 98.8 127.0 1.12e-35
AWR88437.1 putative_response_regulator BGC0001522.5 PKS 34.0 95.8 126.0 1.25e-35
CAH10125.1 putative_repressor-response_regulator BGC0000268.5 PKS 33.0 95.4 128.0 1.63e-35
AEE65471.1 two_component_regulater BGC0000223.5 PKS:Type II 34.0 97.1 126.0 1.67e-35
AZF85922.1 DNA-binding_response_regulator BGC0001963.2 PKS:Type I 33.0 96.2 126.0 2.41e-35
QHZ32185.1 sensory_transduction_protein_regX3 BGC0002047.2 PKS 36.0 96.2 126.0 2.44e-35
AVO00817.1 May18 BGC0001661.5 PKS 35.0 96.7 124.0 8.33e-35
ASY03210.1 NsoR1 BGC0001701.4 ribosomal:RiPP:Lanthipeptide 35.0 96.7 122.0 4.16e-34
AZM50118.1 DNA-binding_response_regulator BGC0002702.3 NRPS:Type I 35.0 95.8 122.0 7.62e-34
OWA25481.1 DNA-binding_response_regulator BGC0001438.5 PKS+saccharide:hybrid/tailoring 34.0 97.9 122.0 1.58e-33
OKI59850.1 transcriptional_regulator BGC0002477.3 PKS 35.0 95.8 120.0 2.54e-33
ASY03216.1 NsoR2 BGC0001701.4 ribosomal:RiPP:Lanthipeptide 37.0 95.8 119.0 9.24e-33
ADJ56358.1 NisR BGC0000535.4 ribosomal:RiPP:Lanthipeptide 32.0 96.7 116.0 1.2e-31
ALK27911.1 putative_two_component_transcription_regulator BGC0001233.5 NRPS:Type I 36.0 95.8 115.0 2.53e-31
AAL15573.1 putative_response_regulator BGC0000511.5 ribosomal:RiPP:Lanthipeptide 34.0 95.8 115.0 3.84e-31
CAG25752.1 putative_two-component_system_response_regulator BGC0000311.6 saccharide+NRPS:Type I 32.0 95.8 113.0 2.38e-30
CAE53348.1 response_regulator BGC0000440.5 NRPS:Type I 31.0 95.8 113.0 2.44e-30
CAG15007.1 two_component_response_regulator BGC0000441.4 NRPS:Type I 31.0 95.8 113.0 2.44e-30
AEX55159.1 putative_response_regulator_SlvR BGC0000549.3 ribosomal:RiPP:Lanthipeptide 30.0 95.0 113.0 2.56e-30
AEA29625.1 Por2 BGC0000409.5 NRPS:Type I 34.0 92.1 112.0 4.93e-30
AAM80541.1 VanRst BGC0000290.5 NRPS:Type I 32.0 97.5 111.0 1.5e-29
AGF91744.1 response_regulator BGC0003168.1 NRPS:Type I+saccharide 32.0 96.2 107.0 6.24e-28
OEI72827.1 two-component_system_response_regulator BGC0002977.1 NRPS:Type I+PKS:Type I 33.0 95.4 106.0 7.28e-28
AGS77305.1 Two_component_response_regulator BGC0001178.5 NRPS:Type I 33.0 95.0 105.0 3.31e-27
CCC21118.1 two_component_transcriptional_regulator BGC0000171.5 PKS:Type I 34.0 95.8 105.0 3.62e-27
AKA59107.1 two-component_system_regulator BGC0001619.5 PKS 31.0 97.1 104.0 6.5e-27
OEI75354.1 DNA-binding_response_regulator BGC0002977.1 NRPS:Type I+PKS:Type I 29.0 99.2 104.0 6.65e-27
QUS58949.1 response_regulator_transcription_factor BGC0002123.3 NRPS:Type I+PKS:Trans-AT type I 30.0 95.8 100.0 1.55e-25
AHI58828.1 WelR3 BGC0000668.5 terpene:Monoterpene+other:other 30.0 83.3 100.0 1.31e-24
QCP68977.1 response_regulator BGC0002296.2 NRPS:Type I+PKS 45.0 52.1 101.0 4.61e-24
DMB38_33825 DNA-binding_response_regulator BGC0002702.3 NRPS:Type I 42.0 51.2 94.0 7.99e-24
CAD91233.1 hypothetical_protein BGC0000289.5 NRPS:Type I+saccharide:hybrid/tailoring 40.0 48.3 94.0 9.08e-24
ACV42481.1 putative_adenylate/guanylate_cyclase BGC0000043.5 PKS 43.0 52.1 97.0 1.8e-22
QXJ26481.1 response_regulator BGC0002370.2 NRPS:Type I 41.0 47.9 89.0 2.29e-22
AGG35708.1 two-component_system_response_regulator BGC0000883.5 other:other 37.0 49.2 87.0 4.93e-21
OEI76089.1 two-component_system_response_regulator BGC0002977.1 NRPS:Type I+PKS:Type I 36.0 49.2 76.0 2.39e-17
OEI73058.1 two-component_system_response_regulator BGC0002977.1 NRPS:Type I+PKS:Type I 26.0 78.3 74.0 1.5e-15
AFL68048.1 response_regulator_with_CheY-like_receiver_domain_and_winged-helix_DNA-binding_domain BGC0001524.3 NRPS:Type I+PKS 27.0 107.5 72.0 1.66e-14
AAZ23070.1 possible_response_regulator BGC0000291.5 NRPS:Type I 26.0 77.9 71.0 3.41e-14
OEI74806.1 sporulation_transcription_factor_Spo0A BGC0002977.1 NRPS:Type I+PKS:Type I 28.0 77.9 69.0 1.66e-13
QUQ72331.1 response_regulator_transcription_factor BGC0002349.3 PKS:Type I 24.0 93.8 68.0 1.98e-13
ABK32252.1 Amb4 BGC0000014.5 PKS 29.0 49.6 69.0 5.46e-13
ABK32284.1 Jer4 BGC0000080.5 PKS 29.0 49.6 69.0 5.46e-13
AYM52876.1 response_regulator BGC0001964.2 PKS 29.0 55.8 67.0 1.31e-12
OEI73132.1 DNA-binding_response_regulator BGC0002977.1 NRPS:Type I+PKS:Type I 28.0 66.2 66.0 1.48e-12
QWT72285.1 response_regulator_transcription_factor BGC0002430.3 NRPS:Type I+saccharide 32.0 48.3 62.0 2.83e-11
OEI73534.1 DNA-binding_response_regulator BGC0002977.1 NRPS:Type I+PKS:Type I 26.0 90.8 61.0 5.06e-11
OEI74374.1 two-component_system_response_regulator BGC0002977.1 NRPS:Type I+PKS:Type I 28.0 48.3 59.0 6.52e-11
AUA09456.1 Transcriptional_regulatory_protein_LiaR BGC0002291.3 PKS 31.0 52.5 61.0 1.3e-10
OEI74235.1 chemotaxis_response_regulator_protein-glutamate_methylesterase BGC0002977.1 NRPS:Type I+PKS:Type I 33.0 55.8 61.0 1.35e-10
ADB02831.1 AzicR2 BGC0000202.5 PKS 32.0 52.9 60.0 1.76e-10
CAB38597.1 two_component_system_response_regulator BGC0000315.5 NRPS:Type I 25.0 72.1 60.0 1.94e-10
ALV82366.1 regulator BGC0001370.4 NRPS:Type I 25.0 72.1 59.0 2.66e-10
WMD04184.1 response_regulator_transcription_factor BGC0002988.1 PKS:Type I 27.0 77.9 59.0 3.27e-10
ctg1_orf18 BGC0000053.5 PKS 29.0 52.5 59.0 3.56e-10
AGM05521.1 two-component_system_response_regulator BGC0002098.2 PKS 25.0 65.8 58.0 9.29e-10
AEG64693.1 two_component_system_response_regulator BGC0000379.5 NRPS:Type I 30.0 51.7 57.0 1.34e-09
OEI76130.1 histidine_kinase BGC0002977.1 NRPS:Type I+PKS:Type I 30.0 68.8 59.0 1.45e-09
BAW35603.1 putative_DNA-binding_response_regulator BGC0002357.3 PKS+other:other 29.0 52.5 57.0 2.07e-09
ADC45530.1 two-component_system_response_regulator BGC0000093.5 PKS:Type I 31.0 49.2 57.0 2.57e-09
CAD60529.1 CinR_protein BGC0000503.5 ribosomal:RiPP:Lanthipeptide 25.0 70.4 56.0 4.13e-09
BCD33686.1 bacterial_regulatory_proteins,_luxR_family BGC0002448.2 NRPS:Type I 27.0 54.2 56.0 4.18e-09
QWF78530.1 Transcriptional_regulatory_protein_LiaR BGC0002142.2 PKS 21.0 95.0 56.0 4.4e-09
ABD65961.1 two-component_system_response_regulator BGC0000341.5 NRPS:Type I 28.0 56.7 55.0 8.27e-09
ABL09961.1 regulator BGC0000197.5 PKS:Type II+saccharide:hybrid/tailoring 30.0 52.1 55.0 8.98e-09
ACI88885.1 AlnR6_two_component_response_regulator BGC0000195.5 PKS:Type II 25.0 57.5 55.0 1.07e-08
AQP25576.1 LuxR_family_response_regulator BGC0001590.5 PKS:Type II aromatic 26.0 53.8 54.0 2.76e-08
AAP03103.1 putative_2-component_system_response_regulator BGC0000874.5 other:other 29.0 56.2 54.0 2.81e-08
UUG47293.1 DNA-binding_response_regulator BGC0002932.1 PKS:Type II aromatic 24.0 92.5 53.0 5.3e-08
QDF63356.1 KyaR BGC0002346.3 ribosomal:RiPP 25.0 79.2 52.0 6.69e-08
OEI75695.1 DNA-binding_response_regulator BGC0002977.1 NRPS:Type I+PKS:Type I 26.0 92.5 52.0 1.18e-07
EHK80177.1 two-component_system_response_regulator BGC0001447.3 PKS 28.0 53.3 52.0 1.19e-07
ABB05090.1 LipReg1 BGC0001003.5 NRPS:Type I+PKS:Type I+saccharide:hybrid/tailoring 21.0 92.9 51.0 1.8e-07
QHZ32201.1 response_regulator_transcription_factor BGC0002307.3 ribosomal:RiPP 27.0 40.8 51.0 1.8e-07
QBC75031.1 DNA-binding_response_regulator BGC0001968.3 NRPS:Type I 26.0 63.7 51.0 2.2e-07
WP_122215947.1 response_regulator_transcription_factor BGC0002015.4 ribosomal:RiPP 25.0 53.3 51.0 2.47e-07
MCG7203797.1 response_regulator_transcription_factor BGC0000248.5 PKS 32.0 37.1 50.0 5.02e-07
BBD82049.1 LuxR_family_transcriptional_regulator BGC0002986.1 ribosomal:RiPP:Lasso peptide 23.0 53.3 49.0 1.52e-06
AAZ23059.1 probable_putative_response_regulator BGC0000291.5 NRPS:Type I 26.0 55.4 48.0 2.1e-06
BAW27696.1 regulator BGC0001764.4 NRPS:Type I 25.0 57.9 48.0 2.66e-06
SFF02396.1 two_component_transcriptional_regulator,_LuxR_family BGC0001674.5 ribosomal:RiPP 23.0 53.3 48.0 2.78e-06
AXG46993.1 chemotaxis_response_regulator_protein-glutamate_methylesterase BGC0000383.5 NRPS:Type I+PKS:Type I 33.0 45.8 48.0 3.31e-06
QBK47604.1 CebA BGC0002316.2 ribosomal:RiPP 28.0 54.2 48.0 3.47e-06
AXO35193.1 DNA-binding_response_regulator_LuxR_family BGC0001848.4 other:other 25.0 42.1 47.0 4.94e-06
OEI73298.1 DNA-binding_response_regulator BGC0002977.1 NRPS:Type I+PKS:Type I 25.0 67.5 47.0 6.14e-06
EWM63043.1 two-component_system_response_regulator BGC0000679.5 terpene 25.0 42.1 47.0 6.68e-06
ARF06225.1 LuxR_family_transcriptional_regulator BGC0001593.5 NRPS:Type I 27.0 62.9 47.0 7.5e-06