LOCUS       BGC0002999             26034 bp    DNA     linear   CON 06-JUL-2015
DEFINITION  Penicillium roqueforti FM164 genomic scaffold, ProqFM164S03, whole
            genome shotgun sequence.
ACCESSION   BGC0002999
VERSION     BGC0002999
KEYWORDS    .
SOURCE      Penicillium roqueforti FM164
  ORGANISM  Penicillium roqueforti FM164
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Penicillium.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 18:41:03
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 26034
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(join(1..1719,1779..5866,5923..6338,6402..6571))
                     /NRPS_PKS="Domain: PKS_AT (317-625). E-value: 2.6e-90.
                     Score: 294.7. Matches aSDomain:
                     nrpspksdomains_PROQFM164_S03g001174_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (700-875). E-value: 1.4e-23.
                     Score: 75.9. Matches aSDomain:
                     nrpspksdomains_PROQFM164_S03g001174_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_ER (1404-1722). E-value: 9.4e-106.
                     Score: 345.3. Matches aSDomain:
                     nrpspksdomains_PROQFM164_S03g001174_PKS_ER.1"
                     /NRPS_PKS="Domain: PKS_KR (1746-1927). E-value: 1.7e-42.
                     Score: 137.3. Matches aSDomain:
                     nrpspksdomains_PROQFM164_S03g001174_PKS_KR.1"
                     /codon_start=1
                     /db_xref="GOA:W6QDA2"
                     /db_xref="InterPro:IPR001227"
                     /db_xref="InterPro:IPR011032"
                     /db_xref="InterPro:IPR013149"
                     /db_xref="InterPro:IPR013154"
                     /db_xref="InterPro:IPR013968"
                     /db_xref="InterPro:IPR014030"
                     /db_xref="InterPro:IPR014031"
                     /db_xref="InterPro:IPR014043"
                     /db_xref="InterPro:IPR016035"
                     /db_xref="InterPro:IPR016036"
                     /db_xref="InterPro:IPR016038"
                     /db_xref="InterPro:IPR016039"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="InterPro:IPR020801"
                     /db_xref="InterPro:IPR020807"
                     /db_xref="InterPro:IPR020843"
                     /db_xref="UniProtKB/TrEMBL:W6QDA2"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021:malonyl CoA-acyl carrier protein transacylase
                     (Score: 167.3; E-value: 1e-50)"
                     /gene_kind="biosynthetic"
                     /inference="profile:GO:0000166"
                     /inference="profile:GO:0003824"
                     /inference="profile:GO:0005515"
                     /inference="profile:GO:0008152"
                     /inference="profile:GO:0008270"
                     /inference="profile:GO:0009058"
                     /inference="profile:GO:0016491"
                     /inference="profile:GO:0016740"
                     /inference="profile:GO:0016747"
                     /inference="profile:GO:0055114"
                     /inference="protein motif:InterPro:IPR000794"
                     /inference="protein motif:InterPro:IPR013154"
                     /inference="protein motif:InterPro:IPR014190"
                     /inference="protein motif:InterPro:IPR021186"
                     /locus_tag="PROQFM164_S03g001174"
                     /note="Alcohol dehydrogenase GroES-like; Leukotriene B4
                     12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase;
                     Fatty acid synthase, alpha subunit, fungi Corresponds to
                     Proq03g054150"
                     /product="Beta-ketoacyl synthase"
                     /protein_id="CDM34450.1"
                     /sec_met_domain="itr_KS (E-value: 1.4e-87, bitscore: 283.5,
                     seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 4.6e-91, bitscore: 294.7,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_N (E-value: 7.2e-08, bitscore: 21.8,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 5.4e-18, bitscore:
                     54.7, seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 1.3e-39, bitscore:
                     125.4, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAGVLSGTSACHTFDTSADGYGRADGIGALYVKRLEDALRDGDP
                     IRSLIRGSAVNANGKTSGISLPSADGQEAVIQKAMAKGGIVPDDITFVECHGTGTKVGD
                     AIEVEALSRVFQRTPNNPLMIGSVKSNVGHSEAASGISSVIKSTLALERGQIPPTHGLK
                     NINPKLKVEDRNIKIPTELTNWPNHSSRVRRVGINSFGYGGANCHVILEQPTKTLSSSR
                     QLRQLPITQSTVILPLSAASTASLEARVADFARYEFGDTDIADLAYTLGSRRTHFAERG
                     FLLAPRSQEISHSFQTRTWVTSASPVTGVASTPFAFVFTGQGSQWPGMCRELLSEFSLF
                     RDTITEMDSVLKSLPGPPSWSLMEAILDVDNPSLIHLPQRSQPCCTAIQVALIRLLSSW
                     EIAPTMTVGHSSGEIAAAFAAGHVSAAEAIVIAYYRGYCVSKSTRVGAMMAIGLSESST
                     TDEIAKAGLDDQIRVACVNSPEGVTVSGDENALDIFLATLQQRNIFARKLKTGGQAYHS
                     HHMVSIGEEYQALLERALPSLGPSIRQPQGASVMSSVTGELKSSGFTASYWRSNLESQV
                     RFAHAIERIHELTEHCFIELGPHSSLELPIKQTLAKAGAELKYAAPIKRNVDSMESILS
                     FAGNLWLKGYEINWSKVNGLQTGLKSVRSMYRVVTDLPPYRFNYENILWNECRASVEYR
                     QRKYPHHELLGSLLTGGNARDKIFRNILKVDDVSWLKDHKLGDTVVFPGAGYLAMAMEA
                     VMQATDAARTDPTFQFSNVNITNALTLNTEFSTSAEIFTSLHKSVITNAATSATWWDFA
                     ISSYHNGSAVQHASGSIAIHPRNAALQSKYKPPSGALESTAKRTWYEKFIRQGLNYGPT
                     FQTISEFYTPRMKSESFASATAPLLKTSGDSISVYPVHPIALDGMIQLAVVAATNGKPK
                     ELRAQIPTRLPSAIVHTSTSSNQTCQMHAVVKRIGFGYTHAGIEMIDSDGQIVAQFDDI
                     RLSPYQSTSQADIEDKRHPVLRVLWKPDIYGLGLMAMDDAQHHVQKFADEAHSPVSGPL
                     LKMGAMLDLLAHKNPRLRILEIGNDVQDITLAVLGLLSAQGSFKRLSAYSTASVSDDGT
                     ILGGLLNLETGERCSSPTELDHEYDLILLPAMNEHIDRAVDTFGGLMADDASILALCPG
                     LTSNSFASRGLDCLPVRLSEDGTTLIVARKPQELQQVSLQRHKFLIVEREKTALGSALA
                     DTLKPIQGQWVMRVRLNELTPAHVSSGTTIFNLCEIKSPLLSVISDDEMARVKVMTDNA
                     TLLVWVTNGNIMHGDRPDFALVSGLARALMLEQPSLKLYTYDIDEPETQIHMTAKRLVS
                     LLTQPGKKPDLEFAQRKGVVHVSRFTPDDSINTLFRNKQGLETTESSLHDAKDVRLAIE
                     QAGQLDTIYFQQLKAPQTIGPTDLRIRVASVGLNAKDYYVLVGRVDTPDATCQLECAGT
                     VEQVGSLVTDFAPGDRVVAMAPSHFQTYQTLPQWACHKLTDAESFDISATLPIVYATAI
                     YALHYRAHIQAGETVLIHSGAGGVGIAAIQLALHAGAEVFTTVSSDEKKKFLVDKLGVK
                     ASNIFSSRDTSFLEGIFSATSGRGVDVILNSLTGDQLHATWRCCAAFGRFVEIGKMDLT
                     TAGRLEMDQFLQSTTFTAFDLSHLYHTDSEQLHSLWNDLLSQVMKLYRQGTITAFEPLN
                     IFDIGETEQAFRYFSSRSRIGKVAINLERAESTIPIQPLRHTTQFDSEKSYVMVGCLGG
                     LGRTLSRWMVNRGARKFTFLGRSGIDKAAARHLVQDLEASGARCEVVRGDVCEASDVEA
                     VITAAAAMGEIGGVVQAAMGLNEAIFSVMPNEYWHTGIDPKVQGSWNLYNSLQMHGRGS
                     HLDFFLMTSSVSGSVGTATESNYCAANHFLDQFSRFLRNQGYPAVAVGLGMISEVGYLH
                     DNPEIEALLLRKGIQAIDADELLQLIDLALSSSATMGISHAHDELAASHLLTGLEAFGL
                     KELRKRGFEGSHPALDDPRANLLASALDGGSDESSQAQNGSLPAEVTTLMQSGHTLDEA
                     VLDHIRRRFGNLVLLKYEVVDVKKPLLQYGMDSMIGAEFRTWFYQSLTTDVPLVMLLGS
                     SCTLESLRDLAMTSLEVGKS"
     protocluster    1..26034
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[0:6571]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..6571
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     cand_cluster    1..26034
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /detection_rules="(indsynth or dmat or indole_PTase)"
                     /kind="neighbouring"
                     /product="T1PKS"
                     /product="indole"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     subregion       1..26034
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0002999"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..26034
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="True"
                     /product="T1PKS"
                     /product="indole"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /rules="(indsynth or dmat or indole_PTase)"
                     /subregion_numbers="1"
                     /tool="antismash"
     aSDomain        complement(613..1155)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PROQFM164_S03g001174_PKS_KR.1"
                     /evalue="1.70E-42"
                     /label="PROQFM164_S03g001174_PKS_KR.1"
                     /locus_tag="PROQFM164_S03g001174"
                     /protein_end="1927"
                     /protein_start="1746"
                     /score="137.3"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="SYVMVGCLGGLGRTLSRWMVNRGARKFTFLGRSGIDKAAARHLVQ
                     DLEASGARCEVVRGDVCEASDVEAVITAAAAMGEIGGVVQAAMGLNEAIFSVMPNEYWH
                     TGIDPKVQGSWNLYNSLQMHGRGSHLDFFLMTSSVSGSVGTATESNYCAANHFLDQFSR
                     FLRNQGYPAVAVGLGMIS"
     aSModule        complement(613..5501)
                     /domains="nrpspksdomains_PROQFM164_S03g001174_PKS_AT.1"
                     /domains="nrpspksdomains_PROQFM164_S03g001174_PKS_DH.1"
                     /domains="nrpspksdomains_PROQFM164_S03g001174_PKS_ER.1"
                     /domains="nrpspksdomains_PROQFM164_S03g001174_PKS_KR.1"
                     /incomplete
                     /locus_tags="PROQFM164_S03g001174"
                     /starter_module
                     /tool="antismash"
                     /type="pks"
     CDS_motif       complement(658..768)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PROQFM164_S03g001174_0011"
                     /evalue="9.40E-14"
                     /label="PKSI-KR_m4"
                     /locus_tag="PROQFM164_S03g001174"
                     /protein_end="1912"
                     /protein_start="1875"
                     /score="43.9"
                     /tool="antismash"
                     /translation="LDFFLMTSSVSGSVGTATESNYCAANHFLDQFSRFLR"
     CDS_motif       complement(1057..1155)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PROQFM164_S03g001174_0010"
                     /evalue="4.90E-13"
                     /label="PKSI-KR_m1"
                     /locus_tag="PROQFM164_S03g001174"
                     /protein_end="1779"
                     /protein_start="1746"
                     /score="41.6"
                     /tool="antismash"
                     /translation="SYVMVGCLGGLGRTLSRWMVNRGARKFTFLGRS"
     aSDomain        complement(join(1228..1719,1779..2240))
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PROQFM164_S03g001174_PKS_ER.1"
                     /evalue="9.40E-106"
                     /label="PROQFM164_S03g001174_PKS_ER.1"
                     /locus_tag="PROQFM164_S03g001174"
                     /protein_end="1722"
                     /protein_start="1404"
                     /score="345.3"
                     /tool="antismash"
                     /translation="GQLDTIYFQQLKAPQTIGPTDLRIRVASVGLNAKDYYVLVGRVDT
                     PDATCQLECAGTVEQVGSLVTDFAPGDRVVAMAPSHFQTYQTLPQWACHKLTDAESFDI
                     SATLPIVYATAIYALHYRAHIQAGETVLIHSGAGGVGIAAIQLALHAGAEVFTTVSSDE
                     KKKFLVDKLGVKASNIFSSRDTSFLEGIFSATSGRGVDVILNSLTGDQLHATWRCCAAF
                     GRFVEIGKMDLTTAGRLEMDQFLQSTTFTAFDLSHLYHTDSEQLHSLWNDLLSQVMKLY
                     RQGTITAFEPLNIFDIGETEQAFRYFSSRSRIGKVAI"
     CDS_motif       complement(1561..1599)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PROQFM164_S03g001174_0009"
                     /evalue="5.60E-05"
                     /label="PKSI-ER_m7"
                     /locus_tag="PROQFM164_S03g001174"
                     /protein_end="1611"
                     /protein_start="1598"
                     /score="15.6"
                     /tool="antismash"
                     /translation="TSGRGVDVILNSL"
     CDS_motif       complement(join(1678..1719,1779..1787))
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PROQFM164_S03g001174_0008"
                     /evalue="1.50E-07"
                     /label="PKSI-ER_m6"
                     /locus_tag="PROQFM164_S03g001174"
                     /protein_end="1572"
                     /protein_start="1555"
                     /score="23.7"
                     /tool="antismash"
                     /translation="GAEVFTTVSSDEKKKFL"
     CDS_motif       complement(1797..1859)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PROQFM164_S03g001174_0007"
                     /evalue="2.00E-10"
                     /label="PKSI-ER_m5"
                     /locus_tag="PROQFM164_S03g001174"
                     /protein_end="1552"
                     /protein_start="1531"
                     /score="32.8"
                     /tool="antismash"
                     /translation="GETVLIHSGAGGVGIAAIQLA"
     CDS_motif       complement(1884..1925)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PROQFM164_S03g001174_0006"
                     /evalue="7.40E-04"
                     /label="PKSI-ER_m4"
                     /locus_tag="PROQFM164_S03g001174"
                     /protein_end="1523"
                     /protein_start="1509"
                     /score="13.0"
                     /tool="antismash"
                     /translation="ATLPIVYATAIYAL"
     aSDomain        complement(3828..4352)
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PROQFM164_S03g001174_PKS_DH.1"
                     /evalue="1.40E-23"
                     /label="PROQFM164_S03g001174_PKS_DH.1"
                     /locus_tag="PROQFM164_S03g001174"
                     /protein_end="875"
                     /protein_start="700"
                     /score="75.9"
                     /tool="antismash"
                     /translation="HELLGSLLTGGNARDKIFRNILKVDDVSWLKDHKLGDTVVFPGAG
                     YLAMAMEAVMQATDAARTDPTFQFSNVNITNALTLNTEFSTSAEIFTSLHKSVITNAAT
                     SATWWDFAISSYHNGSAVQHASGSIAIHPRNAALQSKYKPPSGALESTAKRTWYEKFIR
                     QGLNYGPTFQTI"
     CDS_motif       complement(4191..4268)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PROQFM164_S03g001174_0005"
                     /evalue="7.90E-13"
                     /label="PKSI-DH_m2"
                     /locus_tag="PROQFM164_S03g001174"
                     /protein_end="754"
                     /protein_start="728"
                     /score="40.7"
                     /tool="antismash"
                     /translation="WLKDHKLGDTVVFPGAGYLAMAMEAV"
     aSDomain        complement(4578..5501)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PROQFM164_S03g001174_PKS_AT.1"
                     /evalue="2.60E-90"
                     /label="PROQFM164_S03g001174_PKS_AT.1"
                     /locus_tag="PROQFM164_S03g001174"
                     /protein_end="625"
                     /protein_start="317"
                     /score="294.7"
                     /specificity="substrate consensus: pk"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFTGQGSQWPGMCRELLSEFSLFRDTITEMDSVLKSLPGPPSWSL
                     MEAILDVDNPSLIHLPQRSQPCCTAIQVALIRLLSSWEIAPTMTVGHSSGEIAAAFAAG
                     HVSAAEAIVIAYYRGYCVSKSTRVGAMMAIGLSESSTTDEIAKAGLDDQIRVACVNSPE
                     GVTVSGDENALDIFLATLQQRNIFARKLKTGGQAYHSHHMVSIGEEYQALLERALPSLG
                     PSIRQPQGASVMSSVTGELKSSGFTASYWRSNLESQVRFAHAIERIHELTEHCFIELGP
                     HSSLELPIKQTLAKAGAELKYAAPIKR"
     CDS_motif       complement(5157..5252)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PROQFM164_S03g001174_0004"
                     /evalue="3.50E-07"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="PROQFM164_S03g001174"
                     /protein_end="432"
                     /protein_start="400"
                     /score="22.9"
                     /tool="antismash"
                     /translation="IAPTMTVGHSSGEIAAAFAAGHVSAAEAIVIA"
     CDS_motif       complement(5451..5504)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PROQFM164_S03g001174_0003"
                     /evalue="2.30E-07"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="PROQFM164_S03g001174"
                     /protein_end="334"
                     /protein_start="316"
                     /score="22.9"
                     /tool="antismash"
                     /translation="FVFTGQGSQWPGMCRELL"
     CDS_motif       complement(6089..6133)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PROQFM164_S03g001174_0002"
                     /evalue="1.40E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="PROQFM164_S03g001174"
                     /protein_end="140"
                     /protein_start="125"
                     /score="11.3"
                     /tool="antismash"
                     /translation="GSVKSNVGHSEAASG"
     CDS_motif       complement(6188..6235)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PROQFM164_S03g001174_0001"
                     /evalue="2.50E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="PROQFM164_S03g001174"
                     /protein_end="107"
                     /protein_start="91"
                     /score="13.2"
                     /tool="antismash"
                     /translation="FVECHGTGTKVGDAIE"
     5'UTR           complement(6572..6591)
                     /locus_tag="PROQFM164_S03g001174"
                     /note="Corresponds to Proq03g054150"
     5'UTR           join(6593..6730,6782..7711)
                     /locus_tag="PROQFM164_S03g001175"
                     /note="Corresponds to Proq03g054160a"
     gene            6593..10471
                     /locus_tag="PROQFM164_S03g001175"
     CDS             join(7712..7809,8073..8125,8178..8346,8407..8414,
                     8464..8606,8678..8769,8822..8958,9018..9169)
                     /codon_start=1
                     /db_xref="GOA:W6QEJ5"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="InterPro:IPR020904"
                     /db_xref="UniProtKB/TrEMBL:W6QEJ5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     107; E-value: 1.8e-32)"
                     /gene_kind="biosynthetic-additional"
                     /inference="profile:GO:0000166"
                     /inference="profile:GO:0008152"
                     /inference="profile:GO:0016491"
                     /inference="protein motif:InterPro:IPR002198"
                     /locus_tag="PROQFM164_S03g001175"
                     /note="Corresponds to Proq03g054160a"
                     /product="Short-chain dehydrogenase/reductase SDR"
                     /protein_id="CDM34451.1"
                     /transl_table=11
                     /translation="MKLSAIWESKNGLRGSGTCSHRRVSTPDIQSPDCGEGGIGHALAL
                     DFKNQGYVVFTTLLAHEPRDHLTDLGIHSFTADVTKDSDIEQLKEAISSLTEGSLSVLV
                     NNAGICYTMTAIDTDVKEVEKMFGVNVFGPMRMVHIFHPLLIKARGKIVNIGSELTDFE
                     ASYNATKAALHHWGNTLRVEMKPLGVEVVNVISGEVGTNILKRDHNRKLPEDSFYRPLE
                     KEFMNHVTRTPRTTTPAEYSRSVVIEVMKQHSTAWFWTGASSGIVRFSEQFFPRTLWVN
                     SL"
     3'UTR           join(9170..9959,10032..10226,10291..10471)
                     /locus_tag="PROQFM164_S03g001175"
                     /note="Corresponds to Proq03g054160a"
     protocluster    9876..26034
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[19875:21387]"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      19876..21387
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="2"
     cand_cluster    9876..26034
                     /candidate_cluster_number="2"
                     /contig_edge="True"
                     /detection_rules="(indsynth or dmat or indole_PTase)"
                     /kind="single"
                     /product="indole"
                     /protoclusters="2"
                     /tool="antismash"
     3'UTR           complement(10473..10492)
                     /locus_tag="PROQFM164_S03g001176"
                     /note="Corresponds to Proq03g054170"
     gene            complement(10473..10768)
                     /locus_tag="PROQFM164_S03g001176"
     CDS             complement(10493..10768)
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:W6QY25"
                     /locus_tag="PROQFM164_S03g001176"
                     /note="unnamed protein product; Corresponds to
                     Proq03g054170"
                     /protein_id="CDM34452.1"
                     /transl_table=11
                     /translation="MSAPKGPITKFPAEGLRHARRFITTHNKEGKGVFAVDDDGDHHRI
                     MVDGLAVANIIYSTSGNPVDMNDDNDLVYARDNEVRRFAGQINLFV"
     3'UTR           complement(11205..11249)
                     /locus_tag="PROQFM164_S03g001177"
                     /note="Corresponds to Proq03g054180"
     gene            complement(11205..12537)
                     /locus_tag="PROQFM164_S03g001177"
     CDS             complement(join(11250..11379,11454..11741,11810..12537))
                     /NRPS_PKS="Domain: PKS_KR (73-161). E-value: 2.5e-08.
                     Score: 25.9. Matches aSDomain:
                     nrpspksdomains_PROQFM164_S03g001177_PKS_KR.1"
                     /codon_start=1
                     /db_xref="GOA:W6QCM8"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:W6QCM8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     79.2; E-value: 5.8e-24)"
                     /gene_kind="biosynthetic-additional"
                     /inference="profile:GO:0000166"
                     /inference="profile:GO:0008152"
                     /inference="profile:GO:0016491"
                     /inference="protein motif:InterPro:IPR002198"
                     /locus_tag="PROQFM164_S03g001177"
                     /note="Corresponds to Proq03g054180"
                     /product="Short-chain dehydrogenase/reductase SDR"
                     /protein_id="CDM34453.1"
                     /transl_table=11
                     /translation="MRNDRPVRITRGSGDLYVYATGITTLSTNFPDDLGKSPSTLPEIS
                     TASMSALSFLYSQLFVEPPVPTHDFQGQTVIITGSNRGIGFEAARHLLRLNVSRLILAA
                     RSAEKGQIAADTLEQLTGRSGVIQVEELDMANQESVQEFATRMEMCRIDAVLLNAGIYT
                     HDFVWADNHESTLTVNVINTFLLAILLLPALRRSSKTWVIQPCISFVASDRHVMYDLPE
                     WKTQNTFQVLNDRQQARMHERYPISKLLEILLARAMAKQLDSNPPNGTGNIIVNSFTPG
                     YCTSGLIENVHGITGFALWLLSKATARTTEVGGRTLVAAIAQGDKSHGKYLNDGHIDES
                     ALSPFVRSQEGILAMEKLWEELMEILEQKRPGIGLLLSPVP"
     aSDomain        complement(12055..12318)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PROQFM164_S03g001177_PKS_KR.1"
                     /evalue="2.50E-08"
                     /label="PROQFM164_S03g001177_PKS_KR.1"
                     /locus_tag="PROQFM164_S03g001177"
                     /protein_end="161"
                     /protein_start="73"
                     /score="25.9"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TVIITGSNRGIGFEAARHLLRLNVSRLILAARSAEKGQIAADTLE
                     QLTGRSGVIQVEELDMANQESVQEFATRMEMCRIDAVLLNAGI"
     CDS_motif       complement(12220..12318)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PROQFM164_S03g001177_0001"
                     /evalue="2.50E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="PROQFM164_S03g001177"
                     /protein_end="106"
                     /protein_start="73"
                     /score="16.9"
                     /tool="antismash"
                     /translation="TVIITGSNRGIGFEAARHLLRLNVSRLILAARS"
     CDS             join(12779..12825,13008..13390,13444..14016,14081..14550)
                     /codon_start=1
                     /db_xref="GOA:W6QJR1"
                     /db_xref="InterPro:IPR001128"
                     /db_xref="InterPro:IPR002401"
                     /db_xref="UniProtKB/TrEMBL:W6QJR1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 184.4; E-value: 6.3e-56)"
                     /gene_kind="biosynthetic-additional"
                     /inference="profile:GO:0005506"
                     /inference="profile:GO:0009055"
                     /inference="profile:GO:0016705"
                     /inference="profile:GO:0020037"
                     /inference="profile:GO:0055114"
                     /inference="protein motif:InterPro:IPR001128"
                     /locus_tag="PROQFM164_S03g001178"
                     /note="Corresponds to Proq03g054190"
                     /product="Cytochrome P450"
                     /protein_id="CDM34454.1"
                     /sec_met_domain="p450 (E-value: 7.8e-76, bitscore: 244.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAIELGLFAKTALASRFTDWAKQYGPVFPLRIGSHGLMVVLTSAY
                     HATHLLDKRSANSSNRPPSFVLGDLVFAGDHPMFMDANERWKLRRKLYFQLMNEARCNT
                     EHIRLVEAEATHLLRDLCLEPDSFMQHPARYSNSIIMSLVFGIRTPHYSSPHCIELQRI
                     VTELSNLGEIGASPPVDWLPFLKYLPERLWGDWKTRAARLRQRVLNLHSPLVDRVLERR
                     KNIGTAATFLDGVLDRQEKLQLTREEIDIMCGNLLEGGTDTMATTILTFFQAMVTYPEV
                     QARAQKQIDSVLTDGECPSWSDYDRLPYVAMIVKEVLRWRPPAPGSFPHTLAQDDEFEG
                     MKFLKGTSVVLNVWGIHNDESRYPSPETFEPSRFAEQTRLASVYANAGDAQKRDHFGYG
                     AGRRICPGIHLAERALFIAMAKLLWGFTVQQKLDSSGNPIPVDVNPATAYRDGFLNQCL
                     PFDIDIKPRLGRQEMIMVAAAKAENDVLSAYE"
     gene            12779..14589
                     /locus_tag="PROQFM164_S03g001178"
     3'UTR           14551..14589
                     /locus_tag="PROQFM164_S03g001178"
                     /note="Corresponds to Proq03g054190"
     3'UTR           complement(15061..15170)
                     /locus_tag="PROQFM164_S03g001179"
                     /note="Corresponds to Proq03g054200"
     gene            complement(15061..16513)
                     /locus_tag="PROQFM164_S03g001179"
     CDS             complement(join(15171..15430,15488..16015,16065..16107))
                     /codon_start=1
                     /db_xref="GOA:W6QDA7"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="InterPro:IPR020904"
                     /db_xref="UniProtKB/TrEMBL:W6QDA7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     191.5; E-value: 3e-58)"
                     /gene_kind="biosynthetic-additional"
                     /inference="profile:GO:0000166"
                     /inference="profile:GO:0008152"
                     /inference="profile:GO:0016491"
                     /inference="protein motif:InterPro:IPR002198"
                     /locus_tag="PROQFM164_S03g001179"
                     /note="Corresponds to Proq03g054200"
                     /product="Short-chain dehydrogenase/reductase SDR"
                     /protein_id="CDM34455.1"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.5e-08,
                     bitscore: 23.4, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALQLNGVAVVTGAGSGIGKAVALAYAAEGARGVVIADLNLEAAL
                     QTARESESIATSPTYRALPVAVDVTDEKSVDRMVTAAVQAFDRIDYSVNSAGIGVKHHK
                     PVYKAEVSEMNAFWQVNVLGTLNCIKSVTKVMKSQSVSTLNKQGKSRQVGRGVILNVGS
                     CNSYIATPDIVPYTTTKHAVMGLTKSAALDLAPHEIRVNAICPGWVNTPMVTAAINGNP
                     DLPEMMRTIIPMSRIAEPEEIADVVLFMTSPRSSYVTGVGWVVDGGTTLQVQTC"
     5'UTR           complement(16108..16513)
                     /locus_tag="PROQFM164_S03g001179"
                     /note="Corresponds to Proq03g054200"
     gene            17257..19053
                     /locus_tag="PROQFM164_S03g001180"
     CDS             join(17257..17541,17591..17804,17881..18281,18346..18722,
                     18801..19053)
                     /codon_start=1
                     /db_xref="GOA:W6QEK0"
                     /db_xref="InterPro:IPR006094"
                     /db_xref="InterPro:IPR012951"
                     /db_xref="InterPro:IPR016166"
                     /db_xref="InterPro:IPR016169"
                     /db_xref="UniProtKB/TrEMBL:W6QEK0"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138:FAD linked oxidase domain protein (Score: 312.3;
                     E-value: 1.4e-94)"
                     /gene_kind="biosynthetic-additional"
                     /inference="profile:GO:0003824"
                     /inference="profile:GO:0008762"
                     /inference="profile:GO:0016491"
                     /inference="profile:GO:0016614"
                     /inference="profile:GO:0050660"
                     /inference="profile:GO:0055114"
                     /inference="protein motif:InterPro:IPR012951"
                     /inference="protein motif:InterPro:IPR016166"
                     /locus_tag="PROQFM164_S03g001180"
                     /note="Corresponds to Proq03g054210 FAD-binding, type 2"
                     /product="Berberine/berberine-like"
                     /protein_id="CDM34456.1"
                     /transl_table=11
                     /translation="MVQISNVWGFGLAIMASLAAAAPKDCPDGLCLRTRANLSPLEVSQ
                     ELGPLISNASSIFGPSDSRWANATARYQQYAAPKFTVVVRVARESDVSVIIKYANRNSL
                     PFYAVNRGHGLPISQAKFSGLEIDMQLLTGITIQSNGKSALFQGGTYDQQVMDTLWEEG
                     YVTTTGSCGCVGMLGPALGGGHGRQQGFHGLISDNILKLNVVLADGTTATVSNTSHTDL
                     FWAMKGAGHNFGVVTSFEMSIYPTQVHSWYYKNYVFTQDKLEDLFEQLNVLQGNGTQPV
                     KMAAQYGIYMMDSTVSATEAIIWWTFGYAGSQSEAQQYLTPFDDLNPLSSTDGNVPFPE
                     VPNVQGTGINNATCDKGLERIVGPAGLQVYNATAQRQIYDLFNRNVKSYPELAASAVVM
                     EGYSVEAVRKVDSDSSAYPMRDDYLLMQTTVSYSPNSTLDNVAIDWVTENQKFWNEGQP
                     TRKPTAYVNYASGRESLEAMYGYEPWRLERLRKLKAKYDPEGRFSYYNPIV"
     3'UTR           complement(19652..19875)
                     /locus_tag="PROQFM164_S03g001181"
                     /note="Corresponds to Proq03g054220"
     gene            complement(19652..21387)
                     /locus_tag="PROQFM164_S03g001181"
     CDS             complement(join(19876..20506,20578..21116,21202..21387))
                     /codon_start=1
                     /db_xref="GOA:W6QY29"
                     /db_xref="InterPro:IPR012148"
                     /db_xref="InterPro:IPR017795"
                     /db_xref="UniProtKB/TrEMBL:W6QY29"
                     /gene_functions="biosynthetic (rule-based-clusters) indole:
                     dmat"
                     /gene_kind="biosynthetic"
                     /inference="profile:GO:0009820"
                     /inference="profile:GO:0050364"
                     /inference="protein motif:InterPro:IPR017795"
                     /locus_tag="PROQFM164_S03g001181"
                     /note="Corresponds to Proq03g054220"
                     /product="Aromatic prenyltransferase, DMATS type"
                     /protein_id="CDM34457.1"
                     /sec_met_domain="dmat (E-value: 3.5e-114, bitscore: 371.4,
                     seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVEVTRPPTKAWATLSPWLPSRGPDADYWWRLTGQHLSNMVEAAG
                     YSTDQQYVALLFHYHWIVPYMGPAPGPDGNLKWKSLLGVEGSPIEYSWKWNTAAGKPDV
                     RYTTEAIGSFTGTLLDPLNQQATLEMLHRIADFVPTVDLTWTNHFFATLYDHDRSKYAK
                     EAAAGAHFTTTVVVAAEWLKNGLNLKTYFVPRRLGQSDGKLPIALWEESLKQLDPNSES
                     RAAMHEFLNNDPEGKLLSPFMLAVDNVVPEKSRLKFYFQSPHTSFASVRQVMTMGGRIP
                     VPESQLQELRSLIAAVTGLDSDFPEDSEVPCISEYNPAAKDNFVEIDLLLSGYLYYFDI
                     APGATVPDIKFYTPVRRYGPDDGALAKGIADWMTSRGRGEYSQRYLDMLADLTEHRKLE
                     DGKGMQTYVSCLFKKSHLDVTSYIGPEAFDPARFLKHKAHTTRSTRRRSDSH"
     5'UTR           21660..21890
                     /locus_tag="PROQFM164_S03g001182"
                     /note="Corresponds to Proq03g054230"
     gene            21660..22703
                     /locus_tag="PROQFM164_S03g001182"
     CDS             21891..22649
                     /NRPS_PKS="Domain: PKS_KR (8-127). E-value: 1.1e-13. Score:
                     43.4. Matches aSDomain:
                     nrpspksdomains_PROQFM164_S03g001182_PKS_KR.1"
                     /codon_start=1
                     /db_xref="GOA:W6QCN3"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:W6QCN3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     147.6; E-value: 7.7e-45)"
                     /gene_kind="biosynthetic-additional"
                     /inference="profile:GO:0000166"
                     /inference="profile:GO:0008152"
                     /inference="profile:GO:0016491"
                     /inference="protein motif:InterPro:IPR002198"
                     /locus_tag="PROQFM164_S03g001182"
                     /note="Corresponds to Proq03g054230"
                     /product="Short-chain dehydrogenase/reductase SDR"
                     /protein_id="CDM34458.1"
                     /transl_table=11
                     /translation="MAAVTKPLVLITGANQGLGFATAQQLASTGQYNLLVAARSQEKAE
                     GAVKQLESSTNSSLTPIVIDLDQDESITAAAKFVEERFGSLDILINNAGINRSSDPNAT
                     LRESYRAVFETNVFGVAVMTATFLPLLRASKYHDRRIVNVTSGLGQIGIAYSPTSEYSA
                     KIWELPIYRSSKSAINMISAVDAVSLEKENILVVLAAPGFCRTNFGGGQGVKSAEEGAR
                     PIVRAATEGSPKELFGKLVDDENTLVEFGW"
     aSDomain        21915..22271
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PROQFM164_S03g001182_PKS_KR.1"
                     /evalue="1.10E-13"
                     /label="PROQFM164_S03g001182_PKS_KR.1"
                     /locus_tag="PROQFM164_S03g001182"
                     /protein_end="127"
                     /protein_start="8"
                     /score="43.4"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VLITGANQGLGFATAQQLASTGQYNLLVAARSQEKAEGAVKQLES
                     STNSSLTPIVIDLDQDESITAAAKFVEERFGSLDILINNAGINRSSDPNATLRESYRAV
                     FETNVFGVAVMTATF"
     CDS_motif       21918..22010
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PROQFM164_S03g001182_0001"
                     /evalue="3.70E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="PROQFM164_S03g001182"
                     /protein_end="40"
                     /protein_start="9"
                     /score="19.6"
                     /tool="antismash"
                     /translation="LITGANQGLGFATAQQLASTGQYNLLVAARS"
     3'UTR           22650..22703
                     /locus_tag="PROQFM164_S03g001182"
                     /note="Corresponds to Proq03g054230"
     gene            23448..26034
                     /locus_tag="PROQFM164_S03g001183"
     CDS             join(23448..24066,24135..25233,25296..26034)
                     /codon_start=1
                     /db_xref="GOA:W6QJR3"
                     /db_xref="InterPro:IPR002938"
                     /db_xref="InterPro:IPR003042"
                     /db_xref="UniProtKB/TrEMBL:W6QJR3"
                     /gene_functions="other (smcogs) SMCOG1087:hypothetical
                     protein (Score: 215.5; E-value: 2.2e-65)"
                     /gene_kind="other"
                     /inference="profile:GO:0008152"
                     /inference="profile:GO:0016491"
                     /inference="protein motif:InterPro:IPR003042"
                     /locus_tag="PROQFM164_S03g001183"
                     /note="Corresponds to Proq03g054240"
                     /product="Aromatic-ring hydroxylase-like"
                     /protein_id="CDM34459.1"
                     /transl_table=11
                     /translation="MLHSPPPFADGLRPLKVIIIGGGIAGLSLANAFEKAPVPIEYVIL
                     EARDTIAPQVGAGIALAPSGCRILDQLGVYDDLEQLVHPVQSSGVCDGQGKSLLPERSD
                     TALLVTARMSYPLGWVERRSVLQVLFKHICHKKSVLTSKRMDRIEHSREQEKPIKVICT
                     DGSFYEGDLVVGADGVHSKTRSEMWRVVEQNICDDFDVQQERRAMMAEYQCMFGISSPI
                     PGLDAGMTDDTLARDVSMVVASGKDGKIFWFLFKRMPQVYHSHEIPRFDSADALKFAEQ
                     YFDFPVQSGASNIKFSDLWERRETATLVPLEEADFAHWTAGRIVCLGDSAHKMTPHTGT
                     GGMLALEHAAVLANIICRLVAQGNKLPLTTSQIGTALSQYDEKRRHRRTSAKIKSTGAS
                     ARMQTLQSLADRLVVRFLLPYAGDIRADQFCDDAIGAEHIEYMPVPARSMTGLMPFNPN
                     RGIGMHESIWPRVLWALPLLGMAVAGLLTMFSVAPFEDAYDFLARRRYREVEIRDKFYH
                     SGLLDDFSRSGVLRFIVSEAHFFYQPFSFFADYGVWYGIMLVESARRANRLNVLSFALL
                     WGMLNMWGIAIFVPIYYFAYYILTPISTFDASDRRLTNLSYTKTILPVLLATHYATFMD
                     AYLSPVRSHRQAAGFLWELFPVWLSLAQAGLARKFLQPSTLKQDRLNNVTRDLPTIRTT
                     ILGLCAVSTAVWQYTVWCSEDSLVNIFIPILSSAQGQTFEQLFAEFLKWDQVFFAIPNL
                     FWIILLFADLRAAGLIHAGWLKISFSALGLIIAGGNGTMLGLMWLYREEVLATRRDRGA
                     VVRPIA"
ORIGIN
        1 tcatgatttt cccacttcca agctggtcat cgccaggtcc ctaagtgact cgagcgtgca
       61 ggacgagccg agcaacatga ccaacggcac atcggttgtc aagctctggt agaaccatgt
      121 tcggaattca gccccaatca tactatccat gccgtattgc agcaaaggct tcttgacatc
      181 cacaacctcg tacttcaaaa ggacgaggtt gccaaatcgc cggcggatgt gatccagcac
      241 agcctcgtcg agggtgtgac ctgattgcat cagggtcgta acctcagcag gtaggcttcc
      301 gttctgcgct tgcgatgact catccgagcc accgtccaag gcgctggcta aaagattggc
      361 gcgtggatcg tccaaagctg gatgggaccc ttcgaagcct ctcttgcgca attcctttag
      421 tccgaaggct tctagacccg tcagaagatg ggaagcggct aattcatcgt gtgcgtgcga
      481 tattcccatt gtagcgctgg atgacaaggc aagatcaatg agctggagga gctcgtcggc
      541 gtcaatggcc tgaatccctt tgcgtaaaag gagggcctca atttcgggat tatcatgtag
      601 atagccgact tctgagatca tacccaagcc aaccgcaacg gccggatatc cttggttgcg
      661 caggaagcga gagaactggt caaggaaatg gtttgcggca cagtagttag actcggtcgc
      721 agtaccgacg ctgccagaga cggaggaagt catcaggaag aaatcaagat gagagccccg
      781 tccgtgcatc tgcaggctgt tgtacaaatt ccaagatcct tgtactttgg ggtcgatgcc
      841 agtatgccag tattcgttgg gcatgacaga gaaaattgct tcattcagac ccatggccgc
      901 ctgcacaact ccgccaatct cacccatggc ggcagccgca gtgataacgg cttcgacatc
      961 agacgcctcg caaacgtcac ctctgactac ctcgcatctg gcacctgatg cttcgaggtc
     1021 ttggaccagg tggcgtgcag ctgccttgtc aataccggat cgacctagga aggtaaattt
     1081 ccgggcacct cggttgacca tccaacgcga aagagtgcgc cccagaccgc ccaagcagcc
     1141 taccatcaca tagctcttct cactgtcaaa ttgcgtggtg tgcctcaggg gttggattgg
     1201 gatggtggac tcagcccgtt caagattaat ggccaccttg ccgattctgc tgcgcgatga
     1261 gaagtaacgg aatgcctgct cagtctcacc gatatcaaaa atattcagcg gctcgaacgc
     1321 ggtgatggtt ccctgccggt agagtttcat gacctgggaa agaaggtcat tccatagaga
     1381 gtgaagctgc tcactatcgg tgtggtagag atggctgaga tcgaaggctg tgaaagtggt
     1441 actttgtagg aattggtcca tttctagacg gccagcggtg gtaaggtcca tcttgccaat
     1501 ctccacaaaa cgaccaaacg ctgcacagca cctccacgtc gcgtgtagct gatcgcctgt
     1561 cagagagttg agaatgacgt ctacgccgcg cccagacgta gcactgaaga taccctcgag
     1621 gaaagaagta tcgcgagagc tgaagatgtt ggatgctttg acgccaagtt tatccaccaa
     1681 gaactttttc ttctcatctg aagagacagt ggtgaacacc ttcacaatgg ttttgttagc
     1741 atgcattcca taaattgaac ggtttcaatt cgacttacct ccgctcctgc atgtagagct
     1801 aattggattg ccgcgatgcc aactccgccg gctccggaat gaatcaagac cgtctcccca
     1861 gcctggatat gggcccggta gtgcaaggca tagatggcgg tggcgtagac tataggtaac
     1921 gtagcgctaa tgtcaaagct ctccgcatcg gtaagcttgt ggcatgccca ctgaggaagg
     1981 gtttgatatg tttggaaatg gcttggtgcc atggcaacga cacgatctcc gggagcgaaa
     2041 tctgtcacaa gagaccctac ttgttcgact gtgccagcgc attccaactg acaggtggcg
     2101 tcgggcgtgt cgactcgtcc aaccaagaca taatagtctt tcgcattgag accgaccgac
     2161 gcgacccgga tgcgcaaatc ggtcgggcca atcgtttgtg gagctttcag ctgctggaaa
     2221 taaatagtgt ccagctgccc agcttgctcg atggcgagtc tcacgtcttt ggcatcgtgt
     2281 aagctagact cggtcgtctc aagtccctgc ttgttgcgga agagggtatt aatgctgtca
     2341 tcgggtgtga accgcgagac gtggaccacc cccttgcgct gcgcaaattc taggtctggc
     2401 ttcttaccag gctgggtgag aagagatacc agacgcttcg cggtcatatg gatttgagtt
     2461 tcaggctcgt caatatcata ggtgtagagc ttaagcgagg gttgttctag catcaatgct
     2521 cgggccaggc cagatacaag agcaaagtcc ggcctgtcac catgcataat attaccattg
     2581 gtaacccaca ccaataatgt tgcgttgtct gtcatgacct tgacgcgggc catctcatcg
     2641 tcagagatga cggatagaag aggagacttt atctcacaga ggttgaaaat tgttgtcccg
     2701 ctcgagacat gtgcgggtgt gagctcattt agccggacgc gcatcaccca ttgtccttgg
     2761 atgggtttca gggtatccgc cagtgcagat ccgagcgcag ttttctcacg ctcaacgatg
     2821 aggaatttgt gcctttgcag tgaaacttgt tgcaattcct gcggcttgcg cgcaacgata
     2881 agtgttgtac catcctcgga aaggcggacg ggaagacaat cgagaccacg cgaggcaaat
     2941 gaattgcttg tcaatccggg gcataaggcc aaaatggatg cgtcgtcggc catcaagccg
     3001 ccaaaggtat ccacggcccg gtcgatatgt tcgttcatcg ccggaagtag gatgaggtca
     3061 tactcatggt ccagttcagt gggactggag cagcgctctc cagtctcaag gtttaagaga
     3121 cctcccaaga tagtgccatc atcagaaact gatgctgtgc tatatgcgga caggcgcttg
     3181 aagctcccct gtgcggatag aagtcccaat acagccaggg tgatgtcttg cacatcattt
     3241 ccaatttcca aaatacggag gcggggattt ttgtgcgcca aaaggtccag catagcgccc
     3301 atcttgagga gcgggccgga caccggtgaa tgggcctcat cagcaaactt ctggacatgg
     3361 tgctgcgcat catccatggc catgagcccc agtccataaa tgtcaggctt ccaaagtacc
     3421 cgaagaactg gatggcgctt atcttctatg tctgcttgac tggtggattg gtacggggag
     3481 agtcgaatat catcgaattg agccacaatt tgtccatcgc tgtcaatcat ttctatacca
     3541 gcatgagtgt atccgaatcc aatccgtttg acgactgcat gcatttggca agtctgattg
     3601 gaggaagtag aagtgtggac gattgccgat ggcagcctcg tgggtatctg ggcacgtaac
     3661 tccttaggtt tgccattggt ggctgcaacc acagctagtt ggatcatgcc gtccaaagcg
     3721 attgggtgca ctggatatac cgaaatggaa tcgccacttg tcttcaatag aggcgctgta
     3781 gcactagcga acgactccga tttcatacgc ggggtataaa attcggagat ggtttggaag
     3841 gttgggccat agttcaaccc ctgcctgatg aatttttcgt accaagtccg cttggctgtg
     3901 gattcaagcg ctccgcttgg tggcttatat tttgactgca gagccgcgtt gcgtgggtga
     3961 atagcgatcg atccagatgc atgctgtacc gcagatccat tgtggtagct tgatatagca
     4021 aagtcccacc aggtggctga tgtggctgca ttggtaatga cagacttgtg cagagaagtg
     4081 aagatctccg cgctggtcga gaattctgtg ttcaaggtca acgcgttcgt gatgttgacg
     4141 ttggagaatt gaaatgtagg gtccgtgcgc gccgcgtcgg tggcctgcat aacagcctcc
     4201 atcgccatcg ccaaataccc tgcaccaggg aaaacgaccg tatcaccaag cttatggtcc
     4261 ttaagccagg agacatcatc caccttgagg atattgcgaa agatcttgtc gcgggcattt
     4321 ccaccggtga gtaggctacc caggagttca tgatgcggat acttgcgctg cctgtattca
     4381 acactggcgc ggcattcgtt ccagaggatg ttctcgtagt tgaagcgata cggtggaaga
     4441 tctgtgacca cgcggtacat agagcgcaca gacttcaacc ctgtctggag gccattgacc
     4501 tttgaccaat tgatctcata ccctttgagc cacaggtttc cagcaaagct caggatgctt
     4561 tccatcgagt ccacattacg cttgattggg gcagcatatt tgagttctgc gccggctttt
     4621 gccaaggttt gcttgatcgg cagttccagt gaagagtgag ggccaagctc gataaaacag
     4681 tgctccgtga gttcatgaat gcgttcaatc gcatgagcaa accgcacctg gctttctagg
     4741 ttgcttctcc agtaacttgc tgtgaatcca gatgacttga gctcaccagt caccgaagac
     4801 atcacagagg caccctgggg ctgtcgaatc gagggaccca aactagggag ggcccgttcc
     4861 aacagggcct ggtactcttc tccaatggat accatgtggt gggagtgata cgcctgcccg
     4921 cctgtcttca gcttgcgcgc gaaaatattc ctctgttgca aagtcgccaa gaagatgtcc
     4981 aatgcattct catcgcctga gacggtgacc ccctccggag agttgacgca agccactcgg
     5041 atctggtcat ccagtcctgc tttcgcaatt tcgtccgtgg tggagctttc agacaagccg
     5101 atagccatca tagcaccgac acgagtagat tttgagacgc agtatccacg atagtaggca
     5161 attacgattg cctcggctgc agagacatga cctgcggcga aggcagctgc gatttcaccc
     5221 gaagagtggc cgactgtcat cgtaggggca atttcccaag aagacagaag tcgaatgagg
     5281 gcaacttgta tcgcagtaca gcatggttga gatcgctgtg gtagatggat gaggcttggg
     5341 ttatcaacat ccaagatcgc ctccatcagt gaccaactgg ggggccctgg gaggctcttg
     5401 aggactgagt ccatctccgt gatggtatcc cggaaaagag aaaattccga gaggagctca
     5461 cgacacatgc cgggccactg agacccctgt ccggtgaaaa caaacgcaaa tggagtagat
     5521 gcaacacctg tgactgggct ggctgatgtt acccaggtgc gtgtctggaa actatgagag
     5581 atttcctgtg accgcggagc aagtaaaaac cctctctcgg caaagtgagt tcgcctggag
     5641 cccaatgtat acgcaaggtc tgcaatatct gtgtcaccaa attcatatcg tgcaaagtcc
     5701 gctacgcggg cttcgaggga ggcggttgag gcagcggata gaggtaggat cactgtggac
     5761 tgggtgatgg gcagttgtct gagctgccga gatgaactca aagtcttggt aggctgctct
     5821 aggataacat gacagttcgc accgccgtaa ccaaaagagt taataccttg agtgatgaat
     5881 tagctgattg gtcttcttgt ctgtcgaaca cgccgtacta accaacacgc cgcactcgag
     5941 acgagtggtt tggccaattc gtcaactcag ttggaatttt gatattcctg tcctcaacct
     6001 tcaactttgg attgatgttt tttaagccat gagtgggtgg aatttggccg cgttcaaggg
     6061 caagggtaga cttgatcacg cttgaaattc cgctcgctgc ttcagaatgt ccgacattac
     6121 ttttcaccga cccgatcatg agggggttat ttggcgtgcg ttgaaacacc cgcgataatg
     6181 cctcaacctc gatggcatcg ccgactttgg tcccggtgcc atgacactcg acaaacgtaa
     6241 tgtcgtccgg aacgattcca cccttggcca tggccttttg gattaccgcc tcctgaccat
     6301 cggcgctggg taaactgatt ccagatgtct tgccattcct ggatacaatc gcatttcagc
     6361 acaaagccag gagttgggga gaaaaaaaaa gcttcactta cgcgttgacc gctgacccac
     6421 gtatcagact ccggattggg tcaccatctc gcagggcatc ttcgagcctc ttgacataca
     6481 aggccccaat gccatccgca cgaccatagc cgtcggcaga agtgtcaaat gtgtggcacg
     6541 ctgatgttcc ggagaggacc ccagctttca ttgtagcaat atgttgctcg gcggactgaa
     6601 tcaggttcgc gccggcaaca atggcggcgt cacattcgcg attctgcagg gctgtacatg
     6661 ccatgtgaag acagtagagt gatgaggagc aggctgtgtc aagaagaaga ctgaatagaa
     6721 gcgaccaaag gtgagaaatc ataaattcca gtggatatgt tgcaatttac gacttaccta
     6781 ggtcctagaa gattgaagac atggctgatg cggtttgcca agattgtagt gcctagaccc
     6841 gttccagagt aacggctcag actacactgg ttagctatga gacctaacaa cggacccatg
     6901 aaaaggacaa tatgtactta ctagtcaggg tcttttagct gcatcaccat gtagtcaaca
     6961 gtgaaatttc ccacataaca tcctgtattt gacccagatg cttgatccag aggtattcct
     7021 gcattttcca tgcattcgta tacaacttca agcatctttc gttgttgagg gtccatatac
     7081 ttcgcttcga ggttgttgat cccaaagaaa ctgttctcaa actctcgcac gtcatcatca
     7141 agaaaataac cgccttctgt gatcatactt ccggggcgat ccatgccctg ggggtgatag
     7201 aagccgtcga cattgaaacg cgatttgggg accttgcatt gggccgatct accattggaa
     7261 atcagatccc aaaattcacg agggcttgaa acttcccctg gtaggcgaca ggctgatggg
     7321 agataaatat tattacaatt cacaaagaca atcaagaagc atgccttacc aattccgcag
     7381 atggcaatgg cctcaccaag gccttcatcc gcaggtgatg aatctagtaa aataggcgac
     7441 atgatgaggt tcacgcgggg caaataaatt tgagcagcca atattgtttc gaaaaagaag
     7501 taatagttcc tatttggaac ttattgagcg tctcttgatc atatacatat gtatatgttt
     7561 accttgaggc taagacccgc catatctggt ctcattgtgc tcattgaaag cgatcgccga
     7621 caaaacacct gcatttacag atatcggaat tctctggaat tgcatgatga ccccggtaaa
     7681 cttggggtta ccgtgtattt tgccgagaaa tatgaagctt tcggccatct gggaatcgaa
     7741 gaacgggctt cgcggctcgg gcacatgcag tcaccgacga gtctctacgc cggacattca
     7801 atctccggag tagcccaatc gcattttctt ggggaaattt tgctctggct atagattcta
     7861 gataacaagg ggccagttac tctgcttgtt gagagatttc tattcccgtg atcttgacag
     7921 tgcatcagaa ctagcgacct ttccagccac tagaatagga ttttattctt cagatatgat
     7981 taccaaggca catactcgtc cttcggtcct gataactggg taaaagcaga ctggatcctg
     8041 tttacaggtt gaaatgctca tgatggaggt agttgcggcg aggggggaat cggacatgct
     8101 ttggcacttg acttcaagaa tcaaggtatg ttacatagaa aatttgtatt aacaagttct
     8161 gatcgttcaa tgtttaggat acgtggtctt caccactctt ctcgcccatg agccacggga
     8221 ccatttgacc gatctcggaa tacactcgtt cactgcggat gttacgaagg acagtgacat
     8281 tgagcagttg aaggaggcca tttcaagctt gacagaaggc agtctgagtg tgcttgttaa
     8341 taatgcgtaa gtaatatatg tctatttttc gttggctgat ctaacgatgg cttcaaactt
     8401 ggatagaggg atatgtgagt gacgaagagc caaaagaggt gataaatggg ctaaaccaag
     8461 caggctatac gatgaccgca atcgatacag atgtgaaaga ggtagagaag atgtttggtg
     8521 tcaatgtttt cggaccgatg cgaatggtcc acatcttcca ccctctactt atcaaagcca
     8581 gggggaagat tgtcaacatt ggcagcgtgg gcggtattgt tccttatgtt tatggatgca
     8641 agttgacttt tgatcgcctg aactgtgctc gagataggag ctgaccgact ttgaagctag
     8701 ctacaatgca acaaaggccg ctctccacca ctggggcaac accttaagag tcgagatgaa
     8761 gccgctcggg taagcctctc tactagaaga tagtcacccg cgctgacttc aataaatgaa
     8821 gtgttgaagt ggtcaatgtt atctccggag aagtgggcac gaacattttg aaacgggatc
     8881 acaatcgcaa actaccagag gactcgtttt accgcccgct cgagaaagag tttatgaacc
     8941 atgtcacaag aacacctcgt gagcatttat ctatttagct ttgtgagcga attgcatagt
     9001 actaacgctt gatacaggca cgactacacc ggcggagtat tcccggtccg tcgtcattga
     9061 agtgatgaag caacactcga ctgcttggtt ctggacagga gccagctcgg ggattgtaag
     9121 atttagcgag cagttctttc ctcgtacgct ttgggtaaac tctctataat tccgtttggc
     9181 tgaacaccag cggtacaatg gctaacatcc tgtctctagg actggatatt cactcgacaa
     9241 ttcaacttga acaagcttcg aatgtgagaa ttgagccaag tgactacatc atagaaagcg
     9301 cacacttaaa ctagcttcat agaaatcttt cgagatctac gaaattcacc cagaaaagat
     9361 tcatcccatc acactggtaa tagtctagtt gtataaattt gattgctgaa tgaaccgttc
     9421 cacattcgga agtttgattc aaaaagaaca gcgacaaggc tagactttca cttaactcat
     9481 gccttggtat ttcctcattt ggcaatcatc tcacgttcat gtcgtcacta gcatctcaat
     9541 cagtgcagat ccatgtgata cccaaacttt gaagttatta taagtgtcac gaggatacaa
     9601 aacctgtgat acgagggatg catgtaacta ggaaactaaa gataggaagg aagaagaaag
     9661 aaatagaatg atacggcgag cccacttata atatagatcg accaatcata tcaacaaaaa
     9721 ccatcgtcaa tgcaaacaaa ataaacacca cgagcttgtt gctcgtgaca taccggtttt
     9781 atgatatatc cagtcttgca gaccattgct ttcatccagc taggtaattt gcatatgtaa
     9841 cgctttatta gaggtattta agggaactta tgaaagtggc aaagaatatg tatttgagaa
     9901 atgaaaaggt cattagaaag gttattgaac gatatattgt tcttctgtgt actgaaaagg
     9961 taagccgata taggactata aaatgatttc ccttcgctct agcaagtatg gattttacat
    10021 gactgctgca gaaagatggc ttcacttgcg gtgatcactg cttcacatcc gcgtagtcct
    10081 tttccaaaat ccccaagtgc tcagtaatct cttccccatt caccttcgtc ggagtcacat
    10141 cgagcaggac aaataacatg cgtcccggtc ggttttcgtc taagttcttc cacatatgca
    10201 tacagcctcg gttcacacct aattgggtca gccacaaaat actattggaa tttatcgaaa
    10261 gcgtaagcaa agacttactc atatcaccag gcaacatcaa cttcttctcg ccactgtcaa
    10321 gtgtgagctc aaaagctccc tccaccacga tgccgtaatc aattgataag gcacggtgaa
    10381 tgggcgattc cacgcctggg ccaaagtcaa tcaaacgaac aacacttccg tttgagacat
    10441 gaatgggggg ctaagaggga caaagccaag tgttagcaga cgcgatccat aatcagacaa
    10501 ataggttgat ttgcccagca aaccttcgta cctcattgtc gcgtgcataa accaggtcat
    10561 tatcatcatt catgtccact ggattcccag aggtgctgta aatgatgttt gcgaccgcca
    10621 gcccatccac catgatccgg tggtggtctc catcatcgtc aacagcaaat acgcctttgc
    10681 cttccttgtt gtgggttgta atgaacctgc gcgcatggcg aaggccttcg gccggaaact
    10741 tggtaatagg tcccttagga gcggacatgg caattttccc aaagtaaagt agtaagatat
    10801 cttgtctttc gttatgaaag gttagagata attgccacga aaaagaaata tcttctctat
    10861 gtataacaaa cctgagagcg tctctgctca tgggaattgt cggaacaccg acgtatatcg
    10921 aataccatac gccctcctgt cttcaaatca ccggtaatta tcaatatagg aagtctatta
    10981 ctagcgcaga tatcggaaaa ctcgggcaag ttatcaaacc ccgtgacgaa ttggcccttt
    11041 ccgagtcatc attagcagga gcttcgggaa tacctaggtg cgagatcggg aattcagaag
    11101 gtgtggcatt ttgaaaaaat ataccgaatg ccaacctaca gaatcaagca atctagtaat
    11161 tccaggatat acatgattag gaggggttca tcatcatcat atactaaaaa aaggacttca
    11221 agttaaaaat ctggatcaag tacattacat tatggtacag gactgaggag tagaccaatt
    11281 ccaggtcgct tctgctctaa aatttccatc agttcttccc atagcttctc catcgccaat
    11341 atgccttctt gacttcttac gaatggagac aatgctgatc tgatgataaa aggcatgggt
    11401 cagccacggc ttgaaaattg tatgaagaga gatattctcg gaagggttca tactcatcaa
    11461 tatggccgtc atttaggtac tttccatgac ttttgtcccc ttgcgcaata gctgcgacca
    11521 atgtgcgacc tccaacttct gtcgtccgag cggtggcctt gctcagaagc cagagcgcga
    11581 accctgtgat cccgtgcaca ttctcgatga gaccagaagt gcagtagcca ggtgtgaatg
    11641 aattgacaat tatattgccg gtgccgttag gagggtttga atcaagttgt tttgccatcg
    11701 ccctcgcaag tagtatctcc aacaatttgg agatgggata cctgagaatg ttacatcagt
    11761 tcttttcggc cttgtttgca atgtgtaaaa gacaatagat tgaactcacc tttcatgcat
    11821 cctggcttgc tgtcgatcat tcaaaacttg gaaggtgttt tgtgttttcc actctgggag
    11881 atcatacatt acgtgcctgt cggatgccac gaaactgatg cagggctgaa tcacccatgt
    11941 tttggatgag cgtctgagtg ctggaagaag cagtatagcc agcaaaaacg tattaatcac
    12001 gttcacggtc aacgtgcttt catgattgtc ggcccaaaca aagtcatggg tgtagatacc
    12061 tgcatttagc agaacggcgt ctattcgaca catttccatt cgggtagcaa attcctgcac
    12121 tgactcttga ttggccatat ccagttcctc gacttggatg actccagatc gccccgtcaa
    12181 ctgttcgagt gtatccgcgg ctatctggcc tttctcagct gaccgtgcag ctaatatgag
    12241 tcgactcaca ttcaatctca acaaatgacg ggcagcctca aaaccgatgc ccctgttaga
    12301 tccagtgatg ataacagttt ggccttggaa gtcatgcgtg ggaactggcg gctcgacgaa
    12361 gagctgagag tagaggaacg aaagcgccga catacttgcg gtggagattt ctggcagcgt
    12421 agaaggtgat ttacccaagt catcggggaa attagtcgac agggttgtaa tcccagtggc
    12481 ataaacatag agatccccgc ttccccgagt gatcctaaca ggtcggtcat tacgcatttg
    12541 ccgagacgca agagagaagg gaaaacttgg atctattccc gttctggtct gtcaatgtgc
    12601 ccatatcctt ctgtaatttg tgatttgaag ccgcgtttgg aggggcccac cacatggtgc
    12661 agtagaatct acacagctat aatgagtgat atcactgctg ctttcgcatg ttttagccat
    12721 caagtgtaaa catggcagca attttattct tgggaccttt agttctcatc ctagccgtat
    12781 ggctatcgag ctgggtcttt tcgccaaaac agcgcttgcc tcccggtagg agaaaatttg
    12841 ggctcaacct atactttgaa ctcttcatta agatcatctt gcaggacctc agacactccc
    12901 tttcattgga aatattcacc aatttcccag ggcgggtatc cacttgcggt acttaggact
    12961 gctcaaccct cactttcttg cattgtcgct aatgagaact cccacagatt caccgactgg
    13021 gcgaagcaat atggtcccgt ctttccactc aggattggtt cgcatggtct catggtggtt
    13081 ttgacttctg cgtaccatgc aacacatctc ctagataagc gctcagccaa ctcgagcaat
    13141 cggccgccat cctttgtgct gggcgacctg gtctttgctg gtgaccatcc tatgtttatg
    13201 gatgcgaacg agcggtggaa actcagacga aagctttact ttcagctaat gaatgaggcg
    13261 cggtgtaaca cggagcatat acgtctcgtc gaggcagaag ccacacattt gctacgcgac
    13321 ttgtgcctcg agccggattc gtttatgcag catcctgcta gatacagcaa cagcattatc
    13381 atgagtttgg gtaagtgtaa ttctcatgga acaagatcag ctgctaattt cggatgatgt
    13441 tagtgtttgg cattcgcaca cctcactact ctagccccca ctgcattgag ctgcaacgca
    13501 tagtaacaga attgagcaat ttgggcgaga ttggtgccag cccaccggta gattggctgc
    13561 cgtttctcaa atatctcccg gagcgactct ggggtgattg gaagacacga gccgctcgac
    13621 ttcgtcaacg agtcctgaac ctccattccc ctcttgtgga tcgggtactg gaacgccgca
    13681 agaatattgg tactgctgcg actttccttg atggagttct tgatcggcag gagaagctgc
    13741 aactcaccag agaagaaata gatatcatgt gtggcaactt actcgaaggt gggacagaca
    13801 ccatggctac gacaatactc accttctttc aagccatggt cacgtaccct gaagttcagg
    13861 ccagagctca aaagcagatc gatagtgttc tcaccgatgg agagtgtcca tcctggagtg
    13921 actatgatcg gctaccctat gtggcgatga ttgtcaagga agtcttgcgt tggcgacctc
    13981 cagctccagg atcattcccc catactctag ctcaaggtat gctgaaactt accctatgat
    14041 cgagaatgaa acagagcaat acgctcatat gttgatatag atgacgaatt tgaagggatg
    14101 aaattcctca aggggacatc cgtggtgctc aacgtctggg gtattcacaa tgatgagtcc
    14161 cgctacccaa gccccgagac tttcgaaccg tctcgatttg ccgagcaaac ccgactcgct
    14221 tcagtttatg ccaatgctgg tgatgcacaa aagcgtgatc attttggcta tggagcaggt
    14281 cgacggatct gtcctggcat tcatttggct gaacgcgcgc ttttcatagc tatggctaag
    14341 cttctatggg gatttactgt tcaacagaag ttggatagtt ccggcaatcc tattcctgtt
    14401 gatgtcaacc cggccacagc ataccgcgat gggttcttaa atcagtgtct gcctttcgat
    14461 attgacatca agccccgact ggggagacaa gagatgatca tggtcgccgc ggcaaaggca
    14521 gaaaatgatg ttctcagcgc ctatgaatag tcttaaacta gttaaaccac gaatttgaag
    14581 gagacgacag ttcacccacc ctacatgcca ttttttttac ccaaccggtg gcctacccaa
    14641 atcacgtgac tggtagccta tcttatcttc actggttggg tcaacttctg taatttggtt
    14701 tttaaacctc accaatacct taacaatacc agctttccac caatcatttc tcgtcaatac
    14761 ctccacttga ggcgaatcag ggagggataa caccttaata agaccgtaat agtatgttat
    14821 tctatacatt catagaacat atagtatgtc tgttgtataa taacacctca ataagacctt
    14881 gatgtaatta gtcaactagg cccccagtaa ctgactagta atgatttaat taatgtgcgc
    14941 aatctcaaga ccattaaata atcactgata agctcaccca aacggtggat atctcacgtg
    15001 atttgggtgg gccaccggtt gggtgaactg ccccggtcgc gatgcacctt cgttgtatag
    15061 cttctataaa actctgagac taacgatata ccgttgagaa cagcatttta tcaacctaaa
    15121 gatgtggaat tgctagtaat gtacccggct cagagagata catgatcatt tcaacaagtt
    15181 tgcacttgca gcgttgttcc accgtctaca acccaaccga caccagttac atagctcgat
    15241 ctggggctag tcataaataa gaccacgtct gcaatctctt ccggctcggc aatacgtgac
    15301 atgggaataa ttgttcgcat catctcaggg agatccgggt ttccattaat ggctgcagtc
    15361 accataggtg tattgaccca gcctgggcaa atcgcattga cacgtatctc atgcggtgct
    15421 agatcgaggg ctgcaaagca agaaaatata agcctggatt ttggagttta ttcgaattcc
    15481 gacataccgg cactcttggt caaccccata acagcatgct tcgtcgtcgt atatgggaca
    15541 atatctggcg tcgcgatata cgaattgcat gatcccacgt tcaaaatgac gcctcggcca
    15601 acttggcgtg atttcccctg tttgttcaag gtgctgacac tctgtgattt cataaccttg
    15661 gtcacggact tgatacagtt gagtgttccc aacacgttga cctgccagaa ggcgttcatc
    15721 tcagaaacct ccgccttata gacgggcttg tgatgtttga ccccgatccc agcgctgttc
    15781 acactataat caatgcggtc aaatgcctga actgctgccg tgaccatacg gtcgacactt
    15841 ttctcgtcgg tcacatcaac agccacggga agtgcccggt aggtggggct agtagctatt
    15901 gattcactct ctcgtgccgt ctggagtgca gcctcgaggt tcaaatcggc tataaccaca
    15961 ccccgggcgc cttcggcggc ataggcgagg gcgactgctt taccaatacc actgcctaga
    16021 aacgtcagaa ccggtactac gaaagcctcc gaacagcatc ctaccagcac cagtcaccac
    16081 tgcaacccca ttgagttgta gggccatgtt tatttcgctg cgatcaaact ttgaaaacgg
    16141 ctcgagtgaa cgaatacctt gacgcctgga acatggatga atctcttgtt ttattattgt
    16201 tcttcatcga caaagtaata aagtgtacaa ggaacactga ttgtcaacct tggcgatcgc
    16261 tctgcgtgga tcgattgaat cgccgacgtc cccgacgttc ccgacatccc cgagatgaga
    16321 ttgggattag atcacagaag tttcccgatc acggatgccc ctgcattaag tccggtggaa
    16381 ttaaacatca gtttcgcttt cttatgtccg atcggtagtt gttgcaggcg gaacgagcgt
    16441 gaccagcaat ggggccaaga actacgcatt gaatgaaacg ggctctttgg cagacttcgc
    16501 aacattttgc ataatccaag atttatttat actacgtatc aagcagtctt gtagaacggt
    16561 cgaaaattat atctagtttt catcgcagac gtagtctatg agcaattttg ttgggcggtt
    16621 ttcagctgaa cgtgtaatga tctccagata ttcgtagatg gggaaatcac tatggatccc
    16681 agtttcatat aggtcccatt ctcactctcc gatatgaatt taacagaacc ttgatgtgtg
    16741 ccttgccact cacctttcag ctttcggggc gccccttttt aacgcagtaa gatcgtcttt
    16801 ctgactgcat agttcatagc ctaagaatac caagagatct aagtgcatat tgcgtaaaag
    16861 ccaagttagc cagcagagca ttttaggaac aggcaaccat ttggtcgatc tctgaatcac
    16921 aagtttcctc ttcctttgct tcctcttggt atggaatgta cttcagcgcc attcacttac
    16981 tctacaccag ggggcagtgc gctagcgcgg cttacatctc ctgttgtacg tacctctaag
    17041 gctgaatcac actacatttt gttggatttg ggggccaatc taccagtctg agcctcgttc
    17101 tgtcgatgtg gaaatgaatt tcccatgttc ccgatctccg tcggtaactt acagggcaaa
    17161 aaataacatc tggattttta tataaaggtt gataattgtt cacttgaaca agtccaggtt
    17221 cttccatatc acccatctca ctgtatactc aacaggatgg tgcaaatatc gaatgtttgg
    17281 ggctttggtc tcgccattat ggcgtctctg gcagctgctg caccaaaaga ctgtccagac
    17341 ggactctgcc tgagaacacg ggccaatctc agtccactag aagtcagtca agaacttggt
    17401 ccgctgattt ccaacgcctc aagtatcttc ggacctagcg attcacgttg ggcaaatgcc
    17461 acggcgagat atcaacagta tgccgcgccc aaatttacag tggtggtgcg ggttgctcgc
    17521 gaatctgacg tttcagtcat tgtacgtctc cttttccgga ccctcaaatc caaatctaac
    17581 gcccgagaag atcaaatatg ccaatcgcaa cagtcttcca ttctacgcag ttaatcgggg
    17641 ccatggtctt cctatttccc aggccaaatt cagtggcttg gagatcgata tgcaacttct
    17701 tactggaatt actatacagt ctaacggaaa gtccgctctt ttccaaggag gaacgtacga
    17761 tcaacaagtc atggacacgc tatgggagga aggctacgtt acaagtaagt aaaactcgaa
    17821 caaaaaacac ccctactcaa atcaaccaag ggaataccta acattgaatc tggaactcag
    17881 ctactggtag ttgcggttgc gtgggaatgc ttggcccagc tctaggtggc ggacatggac
    17941 gtcagcaagg cttccatggc ttgattagcg acaacattct caagctcaat gttgtcttgg
    18001 ctgatggaac aactgcgact gtttctaaca cctctcatac ggatctcttc tgggcaatga
    18061 agggtgcggg ccataatttt ggagtggtga caagctttga aatgagcatc tacccaaccc
    18121 aagttcattc atggtattac aagaattatg tcttcacgca ggacaaatta gaggacctct
    18181 tcgaacagct gaatgtattg cagggcaatg gaacccagcc agtgaagatg gccgctcaat
    18241 atggcattta catgatggac tctactgtca gtgccaccga ggttagtatt ttccgataga
    18301 tatccgagtg aagttttgct gataatttaa tcacaaaaca aacaggcaat catctggtgg
    18361 acttttggct acgccggctc gcaaagcgag gcacaacagt acctgacgcc gtttgatgac
    18421 ctcaatccac tcagttctac tgacggaaat gttccattcc ctgaagttcc caacgtccag
    18481 gggactggga tcaacaatgc cacttgtgat aagggtcttg aacggatagt cggtcccgct
    18541 gggcttcagg tgtataacgc cacagcgcaa cgccagatct acgatctttt caacagaaat
    18601 gtcaagtcct acccagaact cgccgcttca gctgttgtga tggagggcta ctctgtggag
    18661 gcggttcgaa aagtggactc ggattcatcc gcctatccta tgcgagatga ttacttgctc
    18721 atgtaagtct cagcctttgt ccgggtggtt tgacaattgc aagcgaaagg aaatatacta
    18781 atagttcttt gtttccatag gcaaactacc gtctcctatt ccccaaattc gacactcgat
    18841 aatgttgcca tagattgggt taccgagaac caaaagtttt ggaacgaggg ccagccaaca
    18901 cgaaagccca ctgcgtacgt caattacgca tctggcagag aatcattaga agccatgtat
    18961 ggatatgaac cttggcgttt ggagaggctt cggaaactca aggccaagta tgatcctgag
    19021 ggccgatttt cctactacaa cccaatcgtc tgataaacca actgttcgtg gatgacacgc
    19081 gcacagtgca aatttgtctc catccagcct ttgatctgtt atattgatac aaatcagggg
    19141 ggggctgaga tttttccctt tctctcgttc tcaatacaat gttctatctt gttttaatca
    19201 tttcagataa gctcttcctc atagccctgc cgtggtcgcg aaattagaag gcaataaata
    19261 ttgttctact atttagttca acagttctag acataaatga aacaaagaga ttggctttga
    19321 ggtatcgtaa aaatgctggc aagactgaca agaccaactg gcaaactttc atcaaccagt
    19381 cgctctaccg atgcagtcat caaggctata gccattgaaa ctatgatgcg agccaggact
    19441 ctacgcagat caaccagaaa ctaaagctag agagagaaga agaagaaggg aagagagata
    19501 gagacgccca agccccacct ctagaaacaa tcagccaatc agatccttag caaacaatat
    19561 gatgctacag ttcgtaatga tgcaaacaag gcaaacaact agcaaacatc acatattgtg
    19621 acgacctccc tggtttacat ttcttctgca ctctccacgt atatcgttac atctttccat
    19681 gatctactgc gtcgagtata tctcctggaa aaaaaaattt ttatcgaagc taacctatat
    19741 aattagtaag atacttaatt gtgccacagt atgatgagga agacccttca gcactcaggg
    19801 gtagttgaga aatgatagga aatcaattat gaccatatta acatagaact aatgattctt
    19861 cgtctgctct gcctatcaat gactatcgct ccgtcttcgg gtggaccggg tggtgtgtgc
    19921 tttatgcttc agaaagcggg cgggatcaaa tgcctccggg ccaatatagg acgtaacgtc
    19981 caagtggctc ttcttgaaca gacaactaac gtatgtctgc atgccctttc catcttctag
    20041 tttgcgatgc tcggtgagat ctgcaagcat gtccaggtat ctctggctat attcacccct
    20101 tccgcgagat gtcatccagt cagcgatgcc ttttgcaagg gcaccatcgt ccggtccata
    20161 gcgacgaaca ggagtataaa atttgatatc cggcactgtt gctccaggag caatatcgaa
    20221 atagtataaa tacccagaaa gcaaaagatc aatctcaacg aagttatctt tagcggctgg
    20281 gttgtactct gatatgcaag ggacctcaga atcctcaggg aagtccgagt ctaggcctgt
    20341 aacagctgca atgagactgc ggagctcctg gagctgcgat tcagggacgg ggatgcgccc
    20401 tcccattgtc atgacctgcc gcacagaggc aaagctggta tggggagatt ggaagtagaa
    20461 cttgagcctc gatttttcag ggacgacatt atcaacagcc agcatgctaa gaattctcgt
    20521 tagcaatatt ccaaacgagg aagcatctat tattgagatg caaagataaa ggcttacaag
    20581 gggctcagca attttccttc cgggtcattg ttgagaaatt cgtgcattgc ggctcgagat
    20641 tcactgttcg gatcaagctg cttgagtgat tcttcccaca gagcgatggg caacttccca
    20701 tccgattgac ccagacgacg gggaacaaaa tacgttttga gattcagacc attcttgagc
    20761 cactccgcgg cgactaccac cgtagtggtg aagtgcgcac ctgccgccgc ttccttggca
    20821 tatttggagc ggtcatgatc gtagagggtg gcgaagaaat ggttggtcca ggtaaggtcc
    20881 acagttggca cgaaatctgc tatgcgatgc agcatctcaa gtgtggcttg ctggttcaga
    20941 ggatccaaaa gggttcctgt gaaggagcca attgcctctg tggtgtagcg gacatcgggc
    21001 ttgcctgccg cagtattcca tttccaagaa tattcaatcg gagacccttc aactcccagc
    21061 aaagatttcc atttgaggtt gccgtctggt ccaggtgcgg ggcccatgta gggaacctat
    21121 gctagccact ccgttagtgt tgctgcgttt ctagtgaaac atggagagga agagtggggg
    21181 aaaaggaaca gggatgcgca cgatccaatg atagtggaag agaagtgcca catattgctg
    21241 gtctgttgag tatccagcag cctcgaccat gttagacaga tgctggcctg tcagtctcca
    21301 ccaataatct gcatcaggcc ctcgtgaggg cagccatggt gatagagttg cccatgcctt
    21361 ggtgggtggt cttgtcactt caaccatgat tcgattcaaa caaatgccaa ttcaatgatt
    21421 gatgagatta gcaaagtagt aattatggag tttaatgaga agggatgtat tccaaatata
    21481 tccatcgtgg agatatgttg ttatcctttc gggcttcatg gacctcgccc tggctgcaac
    21541 gaggtagatt ggtacatcga aaaccacagc agcgaaccac ctaggcaatg tttcgggaaa
    21601 tcgggaatct agccctcaac tcgtcgggta tatataaccg gggttaccac ccgtagccgt
    21661 ggacgacttc gggcactaac ttgccagctt gcagggatca tgacttggaa attgtaaatc
    21721 cgattaagtc cgaagtggga tacatcctaa actccgttaa gaccatttct ttccttatga
    21781 tatagtataa ttgcttcgtt tcgctccgca attaattgac catccattgt cttcccacca
    21841 acatcgacat tacaacatct ttcatccctt caaatacaaa ctttcctaca atggccgccg
    21901 tcactaaacc cttggttctg atcaccggtg caaaccaggg cctgggattc gcgacagcac
    21961 aacagcttgc tagcactggc caatataatc ttcttgttgc cgcccgctcc caggaaaaag
    22021 ccgaaggcgc agtcaagcaa ctggagtcta gcaccaatag ctctttgacg cctattgtta
    22081 tcgatcttga ccaagacgaa tctatcactg cggcagccaa gttcgttgaa gagcgtttcg
    22141 gatcgctgga tatcctcatc aacaacgctg gtatcaatag atcgtccgac ccaaatgcta
    22201 ctctgcgcga gagctaccga gctgtgtttg aaacaaatgt tttcggtgtg gcggtgatga
    22261 cagcaacttt cctaccactc ctacgcgcat cgaagtacca tgaccgacgt attgtcaatg
    22321 tgacaagcgg ccttggtcaa attggcatcg cgtactcgcc aacttcagaa tacagtgcta
    22381 agatatggga actgcctatc taccgcagta gcaagtctgc gatcaatatg attagtgctg
    22441 tcgatgctgt cagtctcgag aaagagaaca ttctcgttgt tctagctgcc ccaggcttct
    22501 gtcgtaccaa ctttggaggt ggtcagggcg tcaaatcagc agaggagggg gctcggccta
    22561 ttgtacgggc tgctacagag ggttcgccaa aagaactatt tggaaagctt gtggacgacg
    22621 agaacacgct ggtcgagttc ggctggtaga ttgaactgtt atgaggattg ggagtgacga
    22681 gactagcaat atatttatga gatgttggca ggaatttgtt gagataggtg tgtggggctg
    22741 cctggttact caggtcatct acaaaccgcc gctcgtttac acgcagatct cgagatactt
    22801 ttcggacttt gtcttttaca gaatgaaaac ccctttactc tctctgatat tgtgtttctg
    22861 tgtcattcct cgagcaaatg atacctctcg ttaaactata ccagtacctc tcaggtgaga
    22921 ggatggagaa ttcgccacct ccgttgccct tttcgcgaga tgagcagttt atgttcggta
    22981 gtaatgaatc atgaaacggc cgtgaatatc caaactgtgt gtaaaattct attgatgtaa
    23041 ccaaaaattt cggaaaatat acaaagtgaa agtgatgaag cagtaacgtg ggactcaatg
    23101 acctgggcgt cagttttcca tgggattttc ccactcgaga ttcgaacaaa ttgctttgag
    23161 atccttcaaa agttcagagc tattcaaatc caagcactcc acaaagttat tcggaaagca
    23221 atcgttaggg ccaattgccg agtgcccgat gccttcgtgt agtaatcacc gggttcccga
    23281 attgagagga gaatctcgtg acaattcaaa tcattatact cttaccttga tgctagtcct
    23341 agatagagta ttggtctggc aaaacttgcc ctgtaaaagt tttccaactc ttgaacagcc
    23401 agttcgggcc cttcttgcca ataccttgcc ctccgcacat attcgccatg ttgcactctc
    23461 ctcctccctt tgctgatggg cttcgccccc tcaaagtcat cattatagga ggtgggattg
    23521 ctggtctatc tttggcgaat gcctttgaaa aagcccctgt cccgatcgaa tacgtaattc
    23581 tggaagctcg agacaccatt gcaccacagg tcggagctgg tattgctctt gccccaagcg
    23641 ggtgtcgaat tctcgaccaa ttgggtgtgt atgacgattt ggaacagcta gttcatccgg
    23701 tgcaaagcag cggtgtgtgt gatggacagg gaaagtcgtt attgcccgag cggagtgaca
    23761 ccgcattgct cgtcactgcc cgcatgtcat atccgttggg ttgggtcgag cgtcgaagtg
    23821 tcttgcaagt gctgtttaag cacatctgtc acaagaaaag tgtgttgacg agcaagagga
    23881 tggatcggat cgaacactcc cgtgagcaag agaagcctat caaggtcatc tgcaccgatg
    23941 gctctttcta tgaaggcgat ctggtcgtgg gagccgatgg agttcacagt aaaacgcgct
    24001 cggagatgtg gagggtggtt gagcaaaata tctgtgatga ttttgatgtg cagcaggaac
    24061 gtcgtggtaa gtggccctga atcgtcgaaa ttattaccca tcaatttgta cggatgtact
    24121 aacagggata acagccatga tggctgaata tcagtgcatg tttggtatct ctagccccat
    24181 tccggggttg gacgctggta tgaccgacga cacgcttgca agagacgtgt ccatggtagt
    24241 ggccagtggc aaggacggca agattttttg gtttttgttc aaacgtatgc cacaagtata
    24301 ccacagccat gagattccgc gattcgatag cgcggatgcg ttaaaatttg cagagcaata
    24361 ttttgatttc cctgtccagt ccggtgcgag caacattaag ttttctgatc tgtgggagcg
    24421 gcgcgagacg gcaacactag tccctctcga ggaggcagac ttcgcgcatt ggacagctgg
    24481 tcgcattgtt tgcttgggcg acagtgctca caaaatgaca ccccatactg ggaccggagg
    24541 catgcttgct ctcgaacatg cagcagtgtt ggccaacata atatgccggt tggtggccca
    24601 gggaaacaaa ttaccgctca caacatctca aatcggaacg gccctgagtc aatacgatga
    24661 aaaaagacga caccgtcgca cctccgctaa aataaagtct accggagcgt ctgctcgcat
    24721 gcagacttta cagagtcttg cggatcggct tgttgttcgt ttccttttac cttacgctgg
    24781 tgatattcgt gccgatcaat tttgcgatga tgccattggc gcagagcata ttgaatacat
    24841 gccagttcca gcacgctcta tgacgggctt gatgcctttt aatcccaatc gtggtatcgg
    24901 tatgcatgaa agcatatggc cacgcgtgtt gtgggccttg ccactacttg ggatggcagt
    24961 tgctgggttg ttgactatgt tctccgtggc gccatttgaa gatgcatacg acttccttgc
    25021 tcgtcgtcgc taccgcgaag tggaaatccg agacaaattc taccactctg gtttgctcga
    25081 tgatttctcc aggtcgggag tcctgcgctt catagtcagt gaagcgcact tcttttatca
    25141 gcctttctcc ttttttgccg actatggtgt ttggtatggt atcatgttgg ttgagtctgc
    25201 aaggagagct aaccgactca acgtcctaag tttgtaagtt tgcgacagag tgaccaacac
    25261 tctggatgag accttctaac atactatttc accagtgctc ttctctgggg aatgctcaat
    25321 atgtggggaa tcgccatttt cgttcccatt tactactttg cttactacat cctcacgcca
    25381 atttccacct ttgacgcatc cgacaggcgt ctaacaaatc tttcctatac aaagactatc
    25441 ctgccagtgc ttttggctac ccactatgcc acttttatgg acgcttatct ttctccggtg
    25501 cggtcccacc gtcaggctgc tggcttcttg tgggagctat tccctgtctg gctctctctt
    25561 gcacaggcgg gccttgctcg aaaattcctc caaccgagca cgctgaagca agatcgactc
    25621 aataatgtca cacgcgacct accgactatc cgaacaacca ttctcgggct ttgtgccgtt
    25681 tcgactgcag tttggcagta tacagtctgg tgcagcgagg actcgcttgt aaacatcttc
    25741 atacccatcc ttagtagtgc gcagggccaa acctttgaac agctctttgc cgagttcttg
    25801 aaatgggatc aagtattctt cgctattccg aatttgtttt ggattatact attgtttgct
    25861 gatcttcgtg ccgctggctt gattcatgct ggttggctca aaatatcatt ctcggctctg
    25921 ggtctgataa ttgcgggtgg gaatgggacg atgctaggat tgatgtggct gtatagggaa
    25981 gaggttctgg ctacgagacg agatcgaggt gctgttgtgc gtcccatagc ctga
//
