BGC0000444: thaxtomin A biosynthetic gene cluster from Streptomyces turgidiscabies Car8
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Location: 12,536 - 33,158 nt. (total: 20,623 nt).
This entry is originally from NCBI GenBank AY707081.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000444
Short description thaxtomin A biosynthetic gene cluster from Streptomyces turgidiscabies Car8
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: AY707081.1
Compounds
  • thaxtomin A
Species Streptomyces turgidiscabies Car8 [taxonomy]
References
Chemical products information
thaxtomin A
Copy SMILES
C22H22N4O6
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • stPAI021
  • AAW49313.1
  • nos
12536 - 13738 (-) nitric oxide synthase
copy AA seq
copy Nt seq
  • stPAI022
  • AAW49314.1
13770 - 14990 (-) putative cytochrome P450
copy AA seq
copy Nt seq
  • stPAI023
15669 - 15902 (+)
copy AA seq
copy Nt seq
  • stPAI024
  • AAW49315.1
16241 - 17005 (+) putative transposase
copy AA seq
copy Nt seq
  • stPAI025
17118 - 17337 (-)
copy AA seq
copy Nt seq
  • stPAI026
  • AAW49316.1
17498 - 18721 (+) putative transposase
copy AA seq
copy Nt seq
  • stPAI027
  • AAW49317.1
19073 - 19711 (-) putative araC family regulatory protein
copy AA seq
copy Nt seq
  • pseudo21222_22427
21223 - 22427 (+)
copy AA seq
copy Nt seq
  • stPAI029
  • AAW49318.1
  • txtA
22745 - 27103 (+) thaxtomin synthetase A
copy AA seq
copy Nt seq
  • stPAI030
  • AAW49319.1
  • txtB
27100 - 31617 (+) thaxtomin synthetase B
copy AA seq
copy Nt seq
  • stPAI031
  • AAW49320.1
  • txtC
31971 - 33158 (+) cytochrome P450
copy AA seq
copy Nt seq
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Removed annotation for irrelevant pseudogene
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.