BGC0000444 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000444 (Streptomyces turgidiscabies Car8)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	20,623	pepticinnamin E	NRP + Polyketide	6%

BGC0000444 - Region 1 - NRPS

Download region GenBank file

Download region SVG

Location: 1 - 20,623 nt. (total: 20,623 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 20,624
Label		BGC0000444

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000444.1	0.62	NRP	thaxtomin A	Streptomyces turgidiscabies Car8
BGC0000426.1	0.34	NRP	sevadicin	Paenibacillus larvae
BGC0000465.1	0.33	NRP	xenortide A, xenortide B, xenortide C, xenortide D	Xenorhabdus nematophila ATCC 19061
BGC0000389.1	0.33	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0002071.1	0.32	NRP	Virginiafactin	Pseudomonas sp. QS1027
BGC0001806.1	0.24	NRP	tolaasin A	Pseudomonas tolaasii
BGC0001128.1	0.23	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001758.1	0.23	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001844.1	0.23	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001132.1	0.23	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000444.1	0.85	NRP	thaxtomin A	Streptomyces turgidiscabies Car8
BGC0000426.1	0.67	NRP	sevadicin	Paenibacillus larvae
BGC0000465.1	0.67	NRP	xenortide A, xenortide B, xenortide C, xenortide D	Xenorhabdus nematophila ATCC 19061
BGC0000389.1	0.66	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0002071.1	0.65	NRP	Virginiafactin	Pseudomonas sp. QS1027
BGC0001806.1	0.57	NRP	tolaasin A	Pseudomonas tolaasii
BGC0001128.1	0.57	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001758.1	0.57	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001844.1	0.56	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001132.1	0.56	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061

Similar known gene clusters

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 20623:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (NMe-phe) + (NMe-X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

stPAI029

Search NORINE for peptide: strict or relaxed

AMP-binding (22..421): phe

NRPSPredictor2: phe

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: phe, trp
Single AA prediction:: phe

Stachelhaus prediction details:

Stachelhaus sequence:: DAWTVAAVCK
Nearest Stachelhaus code:: phe
Stachelhaus code match:: 100% (strong)

stPAI030

Search NORINE for peptide: strict or relaxed

AMP-binding (49..448): X

NRPSPredictor2: phe, trp

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: phe, trp
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DGWAVvaVsK
Nearest Stachelhaus code:: trp
Stachelhaus code match:: 70% (weak)