BGC0000012 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000012 (Alternaria solani)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	21,971	alternapyrone	PKS	100%

BGC0000012 - Region 1 - T1PKS

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Location: 1 - 21,971 nt. (total: 21,971 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 21,972
Label		BGC0000012

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000012	1.00	Polyketide	alternapyrone	Alternaria solani
BGC0001924	0.34	Terpene	ascofuranone	Acremonium egyptiacum
BGC0001893	0.34	Other	abscisic acid	Botrytis cinerea B05.10
BGC0002515	0.33	Polyketide	solanapyrone A	Ascochyta rabiei
BGC0002406	0.33	Other	hydroxycinnamoyltyramine	Oryza sativa Japonica Group
BGC0000146	0.33	Polyketide	solanapyrone D	Alternaria solani
BGC0001252	0.33	Polyketide	UNII-YC2Q1O94PT	Alternaria alternata
BGC0002194	0.32	Polyketide	epipyrone A	Epicoccum nigrum
BGC0000677	0.32	Terpene	cyclooctatin	Streptomyces melanosporofaciens
BGC0001528	0.32	Terpene	betaestacin	Phoma betae

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000012	1.00	Polyketide	alternapyrone	Alternaria solani
BGC0001924	0.67	Terpene	ascofuranone	Acremonium egyptiacum
BGC0001893	0.67	Other	abscisic acid	Botrytis cinerea B05.10
BGC0002515	0.66	Polyketide	solanapyrone A	Ascochyta rabiei
BGC0002406	0.66	Other	hydroxycinnamoyltyramine	Oryza sativa Japonica Group
BGC0000146	0.66	Polyketide	solanapyrone D	Alternaria solani
BGC0001252	0.66	Polyketide	UNII-YC2Q1O94PT	Alternaria alternata
BGC0002194	0.66	Polyketide	epipyrone A	Epicoccum nigrum
BGC0000677	0.65	Terpene	cyclooctatin	Streptomyces melanosporofaciens
BGC0001528	0.65	Terpene	betaestacin	Phoma betae

Similar known gene clusters from MIBiG 4.0

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 21971:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Me-pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

alt5

PKS_AT (582..892): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; Methylmalonyl-CoA: 70.8%; Ethylmalonyl-CoA: 66.7%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 99.6
Malonyl-CoA: 82.8
Methoxymalonyl-CoA: 80.7
Ethylmalonyl-CoA: 62.1
Benzoyl-CoA: 43.2
Isobutyryl-CoA: 42.1
trans-1,2-CPDA: 25.3
2-Methylbutyryl-CoA: 25.1
Propionyl-CoA: 24.8
inactive: 18.8
fatty_acid: 16.1
3-Methylbutyryl-CoA: 13.1
CHC-CoA: 11.3
Acetyl-CoA: 0.0