BGC0000014: ambruticin biosynthetic gene cluster from Sorangium cellulosum
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Location: 1 - 100,708 nt. (total: 100,708 nt).
This entry is originally from NCBI GenBank DQ897667.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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resistance
TTA codons
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000014
Short description ambruticin biosynthetic gene cluster from Sorangium cellulosum
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
DQ897667.1
via
Compounds
  • ambruticin
Species Sorangium cellulosum [taxonomy]
References
Chemical products information
ambruticin Evidence:
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C28H42O6
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ABK32246.1
 1 - 979 (-) histidine kinase response regulator
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    • ABK32247.1
    		 976 - 1950 (-) hypothetical protein
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      • ABK32248.1
      		 2126 - 2797 (-) hypothetical protein
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        • ABK32249.1
        • amb1
        		 2782 - 3732 (-) Amb1
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          • ABK32250.1
          • amb2
          		 5316 - 6536 (+) Amb2
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            • ABK32251.1
            • amb3
            		 6678 - 7457 (+) Amb3
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              • ABK32252.1
              • amb4
              		 7454 - 8839 (+) Amb4
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                • ABK32253.1
                • amb5
                		 9649 - 11175 (-) Amb5
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                  • ABK32254.1
                  • amb6
                  		 11205 - 12638 (+) Amb6
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                    • ABK32255.1
                    • ambA
                    		 14581 - 17772 (+) AmbA
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                      • ABK32256.1
                      • ambB
                      		 17829 - 28898 (+) AmbB
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                        • ABK32257.1
                        • ambC
                        		 28895 - 39862 (+) AmbC
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                          • ABK32258.1
                          • ambD
                          		 39859 - 45537 (+) AmbD
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                            • ABK32259.1
                            • ambE
                            		 45534 - 56057 (+) AmbE
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                              • ABK32260.1
                              • ambF
                              		 56054 - 62647 (+) AmbF
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                                • ABK32261.1
                                • ambI
                                		 62644 - 63963 (+) AmbI
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                                  • ABK32262.1
                                  • ambG
                                  		 64142 - 66361 (+) AmbG
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                                    • ABK32263.1
                                    • ambH
                                    		 66403 - 71724 (+) AmbH
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                                      • ABK32264.1
                                      • ambJ
                                      		 71750 - 73171 (+) AmbJ
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                                        • ABK32265.1
                                        • ambP
                                        		 73690 - 74760 (-) AmbP
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                                          • ABK32266.1
                                          • ambO
                                          		 74763 - 75890 (-) AmbO
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                                            • ABK32267.1
                                            • ambN
                                            		 75965 - 77593 (-) AmbN
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                                              • ABK32268.1
                                              • ambQ
                                              		 77623 - 79227 (+) AmbQ
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                                                • ABK32269.1
                                                • ambR
                                                		 79314 - 80654 (+) AmbR
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                                                  • ABK32270.1
                                                  • ambS
                                                  		 80753 - 81832 (+) AmbS
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                                                    • ABK32271.1
                                                    • ambM
                                                    		 81868 - 83055 (-) AmbM
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                                                      • ABK32272.1
                                                      		 83168 - 83422 (-) hypothetical protein
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                                                        • ABK32273.1
                                                        		 83473 - 83733 (-) hypothetical protein
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                                                          • ABK32274.1
                                                          		 83736 - 84137 (-) hypothetical protein
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                                                            • ABK32275.1
                                                            • amb7
                                                            		 84168 - 90431 (-) Amb7
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                                                              • ABK32276.1
                                                              • amb8
                                                              		 90669 - 91376 (-) Amb8
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                                                                • ABK32277.1
                                                                • amb9
                                                                		 91258 - 92376 (+) Amb9
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                                                                  • ABK32278.1
                                                                  		 92547 - 95507 (+) hypothetical protein
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                                                                    • ABK32279.1
                                                                    		 97015 - 99912 (-) hypothetical protein
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                                                                      Biosynthesis information
                                                                      Annotation changelog

                                                                      Entry version: 4

                                                                      Date
                                                                      Changes
                                                                      Submitters
                                                                      Reviewers
                                                                      2022-10-07
                                                                      Update chemical activity to schema version 2.11
                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                      Entry version: 3

                                                                      Date
                                                                      Changes
                                                                      Submitters
                                                                      Reviewers
                                                                      2022-09-15
                                                                      Updated bioactivity data
                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                      Entry version: 2

                                                                      Date
                                                                      Changes
                                                                      Submitters
                                                                      Reviewers
                                                                      2019-10-16
                                                                      Migrated from v1.4
                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                      Entry version: 1

                                                                      Date
                                                                      Changes
                                                                      Submitters
                                                                      Reviewers
                                                                      2015-06-12
                                                                      Submitted
                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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