Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000025.1:
Cluster 1Polyketide19530

BGC0000025, avermectin biosynthetic gene cluster from Streptomyces avermitilis. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: avermectin
PubChem ID: 6858006
SMILES string: Copy to clipboard
Molecular formula: C48H72O14
Average molecular mass: 873.09 Da

Class-specific details

Biosynthetic class(es):
Polyketide
Polyketide synthase subclass:
Type I

Gene cluster description

avermectin (BGC0000025). Gene Cluster 1. Biosynthetic class = Polyketide. GenBank AB032523. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous known gene clusters

Literature references

1. Ikeda H et al. (1999) Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis. Proc Natl Acad Sci U S A 96(17):9509-14.