BGC0000027: ankaflavin biosynthetic gene cluster from Monascus pilosus
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Location: 1 - 80,000 nt. (total: 80,000 nt).
This entry is originally from NCBI GenBank KC148521.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000027
Short description ankaflavin biosynthetic gene cluster from Monascus pilosus
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Iterative type I)
Loci
KC148521.1
via
Compounds
  • ankaflavin
  • monascin
  • rubropunctatine
  • monascorubrin
Species Monascus pilosus [taxonomy]
References
Chemical products information
ankaflavin Evidence:
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C23H30O5
Chemical database entries
NPAtlas
PubCHEM
monascin Evidence:
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C21H26O5
Chemical database entries
NPAtlas
PubCHEM
rubropunctatine Evidence:
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C21H22O5
Chemical database entries
NPAtlas
monascorubrin Evidence:
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C23H26O5
Chemical database entries
PubCHEM
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • 2360
  • AGN71602.1
 10302 - 11051 (+) d-tyrosyl-tRNA(Tyr) deacylase
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    • 2361
    • AGN71603.1
    		 11861 - 12769 (+) peptidyl-prolyl cis-trans isomerase
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      • 2362MpPKS5
      • AGN71604.1
      		 13913 - 22056 (-) conidial yellow pigment biosynthesis polyketide synthase
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        • 2363R1
        • AGN71605.1
        		 24605 - 26315 (+) putative citrinin biosynthesis transcriptional activator CtnR
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          • 2364A
          • AGN71606.1
          		 26467 - 27524 (-) ketoreductase
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            • 2365B
            • AGN71607.1
            		 28132 - 29499 (+) acyltransferase
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              • 2366C
              • AGN71608.1
              		 29639 - 30667 (-) dehydrogenase
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                • 2367B
                • AGN71609.1
                		 31179 - 33685 (+) amino oxidase/esterase
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                  • 2368E
                  • AGN71610.1
                  		 33796 - 34905 (-) putative quinone-oxidoreductase-like protein
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                    • 2369
                    • AGN71611.1
                    		 35220 - 36191 (+) hypothetical protein
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                      • 2370R2
                      • AGN71612.1
                      		 36321 - 37776 (+) putative transcriptional regulatory protein
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                        • 2371MpFasA2
                        • AGN71613.1
                        		 38028 - 43796 (-) fatty acid synthase alpha subunit
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                          • 2372MpFasB2
                          • AGN71614.1
                          		 44432 - 50700 (+) fatty acid synthase beta subunit
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                            • 2373
                            • AGN71615.1
                            		 51201 - 51665 (-) hypothetical protein
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                              • 2374
                              • AGN71616.1
                              		 52222 - 52860 (-) gTP-binding protein rhoA
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                                • 2375
                                • AGN71617.1
                                		 54214 - 55245 (+) hypothetical protein
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                                  • 2376
                                  • AGN71618.1
                                  		 55785 - 56848 (+) myrosinase-binding protein-like protein
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                                    • 2377
                                    • AGN71619.1
                                    		 57499 - 59399 (+) solute carrier family 40 member 1
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                                      • 2378
                                      • AGN71620.1
                                      		 59767 - 59958 (-) hypothetical protein
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                                        • 2379
                                        • AGN71621.1
                                        		 63782 - 65008 (-) hypothetical protein
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                                          • 2380
                                          • AGN71622.1
                                          		 66477 - 67841 (-) dehydratase
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                                            • 2381F
                                            • AGN71623.1
                                            		 68579 - 69950 (-) hydroxylase
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                                              • 2382
                                              • AGN71624.1
                                              		 70854 - 72233 (-) hypothetical protein
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                                                • 2383
                                                • AGN71625.1
                                                		 73916 - 76156 (-) putative HC-toxin efflux carrier TOXA
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                                                  Biosynthesis information
                                                  Annotation changelog

                                                  Entry version: next

                                                  Date
                                                  Changes
                                                  Submitters
                                                  Reviewers
                                                  2024-07-23
                                                  MIBiG v4 annotathon
                                                  • (ID: 7LZK2REXWMB23Y766VYXAX3J)
                                                  • (ID: X3QVFXOIMTNXSB4JQGP4RI6A)
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                  Entry version: 3

                                                  Date
                                                  Changes
                                                  Submitters
                                                  Reviewers
                                                  2022-09-15
                                                  Remove record accession from PKS gene list
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                  Entry version: 2

                                                  Date
                                                  Changes
                                                  Submitters
                                                  Reviewers
                                                  2019-10-16
                                                  Migrated from v1.4
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                  2019-10-16
                                                  Updated compound(s) information (NPAtlas curation)
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                  Entry version: 1

                                                  Date
                                                  Changes
                                                  Submitters
                                                  Reviewers
                                                  2015-06-12
                                                  Submitted
                                                  • (ID: KT6LT7RJM7ROU6KBJOTWGU5X)
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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