BGC0000027: ankaflavin biosynthetic gene cluster from Monascus pilosus
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Location: 1 - 80,000 nt. (total: 80,000 nt).
This entry is originally from NCBI GenBank KC148521.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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Gene details
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General
Compounds
Genes
Polyketide
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000027
Short description ankaflavin biosynthetic gene cluster from Monascus pilosus
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide (Other)
Loci NCBI GenBank: KC148521.1
Compounds
  • ankaflavin
  • monascin
  • rubropunctatine
  • monascorubrin
Species Monascus pilosus [taxonomy]
References
Chemical products information
ankaflavin
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C23H30O5
Chemical database entries
NPAtlas
PubCHEM
monascin
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C21H26O5
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NPAtlas
PubCHEM
rubropunctatine
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C21H22O5
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NPAtlas
monascorubrin
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C23H26O5
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • 2360
  • AGN71602.1
 10302 - 11051 (+) d-tyrosyl-tRNA(Tyr) deacylase
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  • 2361
  • AGN71603.1
 11861 - 12769 (+) peptidyl-prolyl cis-trans isomerase
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  • 2362MpPKS5
  • AGN71604.1
 13913 - 22056 (-) conidial yellow pigment biosynthesis polyketide synthase
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  • 2363R1
  • AGN71605.1
 24605 - 26315 (+) putative citrinin biosynthesis transcriptional activator CtnR
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  • 2364A
  • AGN71606.1
 26467 - 27524 (-) ketoreductase
  • Tailoring (Reduction)
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  • 2365B
  • AGN71607.1
 28132 - 29499 (+) acyltransferase
  • Tailoring (Acylation)
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  • 2366C
  • AGN71608.1
 29639 - 30667 (-) dehydrogenase
  • Tailoring (Reduction)
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  • 2367B
  • AGN71609.1
 31179 - 33685 (+) amino oxidase/esterase
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  • 2368E
  • AGN71610.1
 33796 - 34905 (-) putative quinone-oxidoreductase-like protein
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  • 2369
  • AGN71611.1
 35220 - 36191 (+) hypothetical protein
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  • 2370R2
  • AGN71612.1
 36321 - 37776 (+) putative transcriptional regulatory protein
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  • 2371MpFasA2
  • AGN71613.1
 38028 - 43796 (-) fatty acid synthase alpha subunit
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  • 2372MpFasB2
  • AGN71614.1
 44432 - 50700 (+) fatty acid synthase beta subunit
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  • 2373
  • AGN71615.1
 51201 - 51665 (-) hypothetical protein
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  • 2374
  • AGN71616.1
 52222 - 52860 (-) gTP-binding protein rhoA
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  • 2375
  • AGN71617.1
 54214 - 55245 (+) hypothetical protein
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  • 2376
  • AGN71618.1
 55785 - 56848 (+) myrosinase-binding protein-like protein
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  • 2377
  • AGN71619.1
 57499 - 59399 (+) solute carrier family 40 member 1
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  • 2378
  • AGN71620.1
 59767 - 59958 (-) hypothetical protein
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  • 2379
  • AGN71621.1
 63782 - 65008 (-) hypothetical protein
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  • 2380
  • AGN71622.1
 66477 - 67841 (-) dehydratase
  • Tailoring (Dehydration)
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  • 2381F
  • AGN71623.1
 68579 - 69950 (-) hydroxylase
  • Tailoring (Monooxygenation)
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  • 2382
  • AGN71624.1
 70854 - 72233 (-) hypothetical protein
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  • 2383
  • AGN71625.1
 73916 - 76156 (-) putative HC-toxin efflux carrier TOXA
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Polyketide-specific information
Subclass Other
Starter unit Acetoacetyl-CoA
Cyclic? yes
Release type
  • Hydrolysis
Polyketide-synthases
Genes Properties Modules
2362MpPKS5 Synthase subclass: Iterative type I
Iterative PKS type: Non-reducing, C2-C7 first
Iteration counts: 5
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: KT6LT7RJM7ROU6KBJOTWGU5X, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Remove record accession from PKS gene list
Detailed domain annotation
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