BGC0000027 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000027 (Monascus pilosus)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	80,000	azanigerone A	Polyketide	26%

BGC0000027 - Region 1 - T1PKS

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Location: 1 - 80,000 nt. (total: 80,000 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 80,001
Label		BGC0000027

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000027.1	0.85	Polyketide	ankaflavin, monascin, rubropunctatine, monascorubrin	Monascus pilosus
BGC0000099.1	0.44	Polyketide	monascorubrin	Talaromyces marneffei
BGC0000013.1	0.32	Polyketide	alternariol	Aspergillus nidulans FGSC A4
BGC0001976.1	0.28	Terpene	eupenifeldin	Phoma sp.
BGC0001977.1	0.28	Other	eupenifeldin	Phoma sp.
BGC0000161.1	0.27	Polyketide	isoterrein	Aspergillus terreus NIH2624
BGC0001404.1	0.25	Polyketide	sorbicillin	Penicillium rubens Wisconsin 54-1255
BGC0000048.1	0.25	Polyketide	dothistromin	Dothistroma septosporum
BGC0001280.1	0.24	Polyketide	betaenone C, betaenone A	Phoma betae
BGC0001264.1	0.24	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000027.1	1.00	Polyketide	ankaflavin, monascin, rubropunctatine, monascorubrin	Monascus pilosus
BGC0000099.1	0.74	Polyketide	monascorubrin	Talaromyces marneffei
BGC0000013.1	0.65	Polyketide	alternariol	Aspergillus nidulans FGSC A4
BGC0001541.1	0.63	Polyketide	cercosporin	Cercospora beticola
BGC0000161.1	0.62	Polyketide	isoterrein	Aspergillus terreus NIH2624
BGC0000048.1	0.62	Polyketide	dothistromin	Dothistroma septosporum
BGC0001280.1	0.61	Polyketide	betaenone C, betaenone A	Phoma betae
BGC0001264.1	0.61	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae
BGC0000156.1	0.55	Polyketide	TAN-1612, 1-(2,3,5,10-tetrahydroxy-7-methoxy-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl)pentane-2,4-dione, desmethyl TAN-1612	Aspergillus niger
BGC0001886.1	0.54	Polyketide	secalonic acids	Claviceps purpurea 20.1

Similar known gene clusters

Module view

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 42056:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

2362MpPKS5

PKS_AT (913..1204): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 66.7%; Ethylmalonyl-CoA: 54.2%; Methylmalonyl-CoA: 54.2%

minowa: Methoxymalonyl-CoA

Prediction, score:

Methoxymalonyl-CoA: 55.3
inactive: 54.1
Malonyl-CoA: 49.4
Methylmalonyl-CoA: 43.3
Propionyl-CoA: 25.2
CHC-CoA: 23.0
Ethylmalonyl-CoA: 22.4
2-Methylbutyryl-CoA: 19.3
Acetyl-CoA: 16.6
trans-1,2-CPDA: 14.3
Isobutyryl-CoA: 14.1
fatty_acid: 14.0
3-Methylbutyryl-CoA: 13.2
Benzoyl-CoA: 12.2

2372MpFasB2

PKS_AT (1645..1839): pk

ATSignature: (unknown)

No matches above 50%

minowa: trans-1,2-CPDA

Prediction, score:

trans-1,2-CPDA: 0.0
inactive: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Methylmalonyl-CoA: 0.0
Methoxymalonyl-CoA: 0.0
Malonyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0