BGC0000039: compactin biosynthetic gene cluster from Penicillium citrinum
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 1 - 38,231 nt. (total: 38,231 nt).
This entry is originally from NCBI GenBank AB072893.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000039
Short description compactin biosynthetic gene cluster from Penicillium citrinum
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
AB072893.1
via
Compounds
  • compactin
Species Penicillium citrinum [taxonomy]
References
Chemical products information
compactin Evidence:
Copy SMILES
C23H36O6
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BAC20561.1
  • mlcH
 463 - 1939 (+) transesterase
    copy AA seq
    copy Nt seq
    • BAC20562.1
    • mlcG
    		 2405 - 3666 (-) enoyl reductase
      copy AA seq
      copy Nt seq
      • BAC20563.1
      • mlcF
      		 4120 - 4875 (+) oxidoreductase
        copy AA seq
        copy Nt seq
        • BAC20564.1
        • mlcA
        		 5506 - 15186 (-) polyketide synthase
          copy AA seq
          copy Nt seq
          • BAC20565.1
          • mlcC
          		 15823 - 17508 (+) cytochrome P450
            copy AA seq
            copy Nt seq
            • BAC20566.1
            • mlcB
            		 18389 - 26483 (-) polyketide synthase
              copy AA seq
              copy Nt seq
              • BAC20567.1
              • mlcD
              		 28348 - 31919 (+) HMG-CoA reductase
                copy AA seq
                copy Nt seq
                • BAC20568.1
                • mlcE
                		 32499 - 34686 (-) efflux pump
                  copy AA seq
                  copy Nt seq
                  • BAC20569.1
                  • mlcR
                  		 36315 - 37832 (-) transcription factor
                    copy AA seq
                    copy Nt seq
                    Biosynthesis information
                    Annotation changelog

                    Entry version: 2

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2019-10-16
                    Migrated from v1.4
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    2019-10-16
                    Updated compound(s) information (NPAtlas curation)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                    Entry version: 1

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2015-06-12
                    Submitted
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    Detailed domain annotation
                    Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
                    A domain glossary is available here, and an explanation of the visualisation is available here.
                    Selected features only
                    Show module domains
                    Similar known gene clusters from MIBiG 4.0
                    Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                    Click on reference genes to show details of similarities to genes within the current region.
                    Click on an accession to open that entry in the MiBIG database.