BGC0000040: concanamycin A biosynthetic gene cluster from Streptomyces neyagawaensis
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 1 - 99,892 nt. (total: 99,892 nt).
This entry is originally from NCBI GenBank DQ149987.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000040
Short description concanamycin A biosynthetic gene cluster from Streptomyces neyagawaensis
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
DQ149987.1
via
Compounds
  • concanamycin A
Species Streptomyces neyagawaensis [taxonomy]
References
Chemical products information
concanamycin A Evidence:
Copy SMILES
C46H75N1O14
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AAZ94383.1
 559 - 3324 (-) putative LuxR class regulator
    copy AA seq
    copy Nt seq
    • AAZ94384.1
    		 3408 - 4514 (-) hypothetical protein
      copy AA seq
      copy Nt seq
      • AAZ94385.1
      		 4511 - 5473 (-) putative malonyl transferase
        copy AA seq
        copy Nt seq
        • AAZ94386.1
        		 5746 - 14271 (+) modular polyketide synthase
          copy AA seq
          copy Nt seq
          • AAZ94387.1
          		 14295 - 28772 (+) modular polyketide synthase
            copy AA seq
            copy Nt seq
            • AAZ94388.1
            		 28787 - 43699 (+) nodular polyketide synthase
              copy AA seq
              copy Nt seq
              • AAZ94389.1
              		 43781 - 55729 (+) modular polyketide synthase
                copy AA seq
                copy Nt seq
                • AAZ94390.1
                		 55779 - 70799 (+) modular polyketide synthase
                  copy AA seq
                  copy Nt seq
                  • AAZ94391.1
                  		 70836 - 77006 (+) modular polyketide synthase
                    copy AA seq
                    copy Nt seq
                    • AAZ94392.1
                    		 77034 - 77906 (+) methoxymalonate biosynthesis protein
                      copy AA seq
                      copy Nt seq
                      • AAZ94393.1
                      		 77903 - 78181 (+) methoxymalonate biosynthesis protein
                        copy AA seq
                        copy Nt seq
                        • AAZ94394.1
                        		 78174 - 79289 (+) methoxymalonate biosynthesis protein
                          copy AA seq
                          copy Nt seq
                          • AAZ94395.1
                          		 79286 - 80428 (+) methoxymalonate biosynthesis protein
                            copy AA seq
                            copy Nt seq
                            • AAZ94396.1
                            		 80966 - 81946 (-) putative TDP-glucose 4,6-dehydratase
                              copy AA seq
                              copy Nt seq
                              • AAZ94397.1
                              		 81943 - 82851 (-) TDP glucose synthase
                                copy AA seq
                                copy Nt seq
                                • AAZ94398.1
                                		 83535 - 85547 (-) putative carbamoyltransferase
                                  copy AA seq
                                  copy Nt seq
                                  • AAZ94399.1
                                  		 86031 - 86774 (-) 4-ketoreductase
                                    copy AA seq
                                    copy Nt seq
                                    • AAZ94400.1
                                    		 86774 - 87823 (-) 3-ketoreductase
                                      copy AA seq
                                      copy Nt seq
                                      • AAZ94401.1
                                      		 87823 - 89325 (-) 2,3-dehydratase
                                        copy AA seq
                                        copy Nt seq
                                        • AAZ94402.1
                                        		 89528 - 90781 (-) glycosyltransferase
                                          copy AA seq
                                          copy Nt seq
                                          • AAZ94403.1
                                          		 90973 - 91641 (-) methoxymalonate biosynthesis protein
                                            copy AA seq
                                            copy Nt seq
                                            • AAZ94404.1
                                            		 91758 - 92081 (-) hypothetical protein
                                              copy AA seq
                                              copy Nt seq
                                              • AAZ94405.1
                                              		 92102 - 92914 (-) thioesterase
                                                copy AA seq
                                                copy Nt seq
                                                • AAZ94406.1
                                                		 93058 - 93915 (+) phosphoesterase
                                                  copy AA seq
                                                  copy Nt seq
                                                  • AAZ94407.1
                                                  		 93912 - 94592 (+) phosphopantatheinyl transferase
                                                    copy AA seq
                                                    copy Nt seq
                                                    • AAZ94408.1
                                                    		 94709 - 96814 (+) putative regulator
                                                      copy AA seq
                                                      copy Nt seq
                                                      • AAZ94409.1
                                                      		 97026 - 98438 (+) crotonyl CoA reductase
                                                        copy AA seq
                                                        copy Nt seq
                                                        • AAZ94410.1
                                                        		 98435 - 99298 (+) hydroxybutyryl CoA reductase
                                                          copy AA seq
                                                          copy Nt seq
                                                          Biosynthesis information
                                                          Annotation changelog

                                                          Entry version: 4

                                                          Date
                                                          Changes
                                                          Submitters
                                                          Reviewers
                                                          2022-10-07
                                                          Update chemical activity to schema version 2.11
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                          Entry version: 3

                                                          Date
                                                          Changes
                                                          Submitters
                                                          Reviewers
                                                          2022-09-15
                                                          Updated bioactivity data
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                          Entry version: 2

                                                          Date
                                                          Changes
                                                          Submitters
                                                          Reviewers
                                                          2019-10-16
                                                          Migrated from v1.4
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                          2019-10-16
                                                          Updated compound(s) information (NPAtlas curation)
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                          Entry version: 1

                                                          Date
                                                          Changes
                                                          Submitters
                                                          Reviewers
                                                          2015-06-12
                                                          Submitted
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                          Detailed domain annotation
                                                          Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
                                                          A domain glossary is available here, and an explanation of the visualisation is available here.
                                                          Selected features only
                                                          Show module domains
                                                          Similar known gene clusters from MIBiG 4.0
                                                          Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                                                          Click on reference genes to show details of similarities to genes within the current region.
                                                          Click on an accession to open that entry in the MiBIG database.