BGC0000043 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000043 (Moorena producens 19L)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	13,300	curacin A	PKS	100%

BGC0000043 - Region 1 - T1PKS

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Location: 1 - 13,300 nt. (total: 13,300 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 13,301
Label		BGC0000043

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000043	1.00	Polyketide	curacin A	Moorea producens 19L
BGC0001164	0.22	Polyketide	1-heptadecene	Cyanothece sp. PCC 7822
BGC0001160	0.21	Polyketide	1-nonadecene, (14Z)-1,14-nonadecadiene	Synechococcus sp. PCC 7002
BGC0002240	0.19	Polyketide	BAB, BAA	Metarhizium anisopliae
BGC0002191	0.19	Polyketide	prolipyrone B, gibepyrone D	Fusarium graminearum PH-1
BGC0001254	0.19	Polyketide	ACT-Toxin II	Alternaria alternata
BGC0001400	0.18	Polyketide	citreoviridin	Aspergillus terreus NIH2624
BGC0001276	0.18	Polyketide	6-methylsalicyclic acid	Aspergillus terreus
BGC0002154	0.18	Polyketide	1,3,5,8-tetrahydroxynapthalene, 1-(alpha-l-(2-O-methyl)-6-deoxymannopyranosyloxy)-3,6,8-trimethoxynaphthalene	Pyricularia oryzae 70-15
BGC0001273	0.18	Polyketide	asperlactone	Aspergillus ochraceus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000043	1.00	Polyketide	curacin A	Moorea producens 19L
BGC0001164	0.55	Polyketide	1-heptadecene	Cyanothece sp. PCC 7822
BGC0001160	0.54	Polyketide	1-nonadecene, (14Z)-1,14-nonadecadiene	Synechococcus sp. PCC 7002
BGC0002240	0.51	Polyketide	BAB, BAA	Metarhizium anisopliae
BGC0002191	0.51	Polyketide	prolipyrone B, gibepyrone D	Fusarium graminearum PH-1
BGC0001254	0.50	Polyketide	ACT-Toxin II	Alternaria alternata
BGC0001400	0.50	Polyketide	citreoviridin	Aspergillus terreus NIH2624
BGC0001276	0.50	Polyketide	6-methylsalicyclic acid	Aspergillus terreus
BGC0002154	0.50	Polyketide	1,3,5,8-tetrahydroxynapthalene, 1-(alpha-l-(2-O-methyl)-6-deoxymannopyranosyloxy)-3,6,8-trimethoxynaphthalene	Pyricularia oryzae 70-15
BGC0001273	0.50	Polyketide	asperlactone	Aspergillus ochraceus

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 13300:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ohmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

curM

PKS_AT (566..866): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 95.8%; 2-Rhyd-Malonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 226.5
inactive: 202.0
Methoxymalonyl-CoA: 60.5
Methylmalonyl-CoA: 53.6
Propionyl-CoA: 33.1
Isobutyryl-CoA: 26.0
Benzoyl-CoA: 22.7
Acetyl-CoA: 16.3
CHC-CoA: 13.9
2-Methylbutyryl-CoA: 11.5
3-Methylbutyryl-CoA: 11.0
Ethylmalonyl-CoA: 10.9
trans-1,2-CPDA: 0.0
fatty_acid: 0.0