BGC0000043: curacin A biosynthetic gene cluster from Moorea producens 19L
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Location: 1 - 13,300 nt. (total: 13,300 nt).
This entry is originally from NCBI GenBank GQ412749.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000043
Short description curacin A biosynthetic gene cluster from Moorea producens 19L
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
GQ412749.1
via
Compounds
  • curacin A
Species Moorea producens 19L [taxonomy]
References
Chemical products information
curacin A Evidence: NMR [1]
Copy SMILES
C23H35N1O1S1
Chemical database entries
PubCHEM
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ACV42478.1
  • curM
1 - 6636 (+) polyketide synthase
    copy AA seq
    copy Nt seq
    • ACV42479.1
    7051 - 8061 (+) hypothetical protein
      copy AA seq
      copy Nt seq
      • ACV42480.1
      8510 - 9577 (+) putative tRNA 2-selenouridine synthase
        copy AA seq
        copy Nt seq
        • ACV42481.1
        9627 - 13097 (-) putative adenylate/guanylate cyclase
          copy AA seq
          copy Nt seq
          Biosynthesis information
          Annotation changelog

          Entry version: next

          Date
          Changes
          Submitters
          Reviewers
          MIBiG v4 annotathon
          • (ID: 4ZBJCWV5NZUBDJXCSIV4TKIA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

          Entry version: 4

          Date
          Changes
          Submitters
          Reviewers
          Update chemical activity to schema version 2.11
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

          Entry version: 3

          Date
          Changes
          Submitters
          Reviewers
          Updated bioactivity data
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

          Entry version: 2

          Date
          Changes
          Submitters
          Reviewers
          Migrated from v1.4
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          Updated compound(s) information (NPAtlas curation)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

          Entry version: 1

          Date
          Changes
          Submitters
          Reviewers
          Submitted
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          Detailed domain annotation
          Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
          A domain glossary is available here, and an explanation of the visualisation is available here.
          Selected features only
          Show module domains
          Similar known gene clusters from MIBiG 4.0
          Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
          Click on reference genes to show details of similarities to genes within the current region.
          Click on an accession to open that entry in the MiBIG database.