Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000045.1:
Cluster 1Polyketide131000

BGC0000045, dehydrocurvularin biosynthetic gene cluster from Aspergillus terreus. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: dehydrocurvularin
PubChem ID: 6438143
SMILES string: Copy to clipboard
Molecular formula: C16H18O5
Average molecular mass: 290.315 Da

Class-specific details

Biosynthetic class(es):
Polyketide synthase subclass:
Type I

Gene cluster description

dehydrocurvularin (BGC0000045). Gene Cluster 1. Biosynthetic class = Polyketide. GenBank JX971534, positions 4000-26000. Click on genes for more information.


biosynthetic genes
transport-related genes
regulatory genes
other genes

Domain annotation

Homologous known gene clusters

Literature references

1. Xu Y et al. (2013) Characterization of the biosynthetic genes for 10,11-dehydrocurvularin, a heat shock response-modulating anticancer fungal polyketide from Aspergillus terreus. Appl Environ Microbiol 79(6):2038-47. doi: 10.1128/AEM.03334-12. Epub