BGC0000060: fostriecin biosynthetic gene cluster from Streptomyces pulveraceus
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Location: 1 - 73,577 nt. (total: 73,577 nt).
This entry is originally from NCBI GenBank HQ434551.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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General
Compounds
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Biosynthesis
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KnownClusterBlast
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0000060
Short description fostriecin biosynthetic gene cluster from Streptomyces pulveraceus
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
HQ434551.1
via
Compounds
  • fostriecin
Species Streptomyces pulveraceus [taxonomy]
References
Chemical products information
fostriecin Evidence:
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C19H27O9P1
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AEC13064.1
 162 - 1016 (-) methyltransferase
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    • AEC13065.1
    		 1729 - 2226 (-) MarR family transcriptional regulator
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      • AEC13066.1
      		 2305 - 2946 (+) metallo-beta-lactamase superfamily protein
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        • AEC13067.1
        		 3627 - 6503 (+) LuxR family transcriptional regulator
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          • AEC13068.1
          • fosM
          		 6460 - 7401 (+) fosM
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            • AEC13069.1
            • fosC
            		 7623 - 18251 (+) fosC
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              • AEC13070.1
              • fosD
              		 18288 - 23504 (+) fosD
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                • AEC13071.1
                • fosE
                		 23568 - 34181 (+) fosE
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                  • AEC13072.1
                  • fosF
                  		 34227 - 40022 (+) fosF
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                    • AEC13073.1
                    • fosG
                    		 40129 - 41358 (+) fosG
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                      • AEC13074.1
                      • fosH
                      		 41499 - 42449 (+) fosH
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                        • AEC13075.1
                        • fosI
                        		 42616 - 43890 (+) fosI
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                          • AEC13076.1
                          • fosJ
                          		 43997 - 45259 (+) fosJ
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                            • AEC13077.1
                            • fosK
                            		 45362 - 46558 (-) fosK
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                              • AEC13078.1
                              • fosL
                              		 46843 - 47715 (+) fosL
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                                • AEC13079.1
                                • fosA
                                		 47723 - 57643 (+) fosA
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                                  • AEC13080.1
                                  • fosB
                                  		 57736 - 63378 (+) fosB
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                                    • AEC13081.1
                                    		 65820 - 67109 (+) GH3-superfamily protein
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                                      • AEC13082.1
                                      		 67283 - 69451 (+) 3-hydroxy-3-methylglutaryl coenzyme A reductase
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                                        • AEC13083.1
                                        		 70385 - 71161 (+) thioesterase
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                                          • AEC13084.1
                                          		 71676 - 73577 (+) heat shock protein
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                                            Biosynthesis information

                                            No biosynthesis information available for this record.

                                            Annotation changelog

                                            Entry version: 4

                                            Date
                                            Changes
                                            Submitters
                                            Reviewers
                                            2022-10-07
                                            Update chemical activity to schema version 2.11
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                            Entry version: 3

                                            Date
                                            Changes
                                            Submitters
                                            Reviewers
                                            2022-09-15
                                            Updated bioactivity data
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                            Entry version: 2

                                            Date
                                            Changes
                                            Submitters
                                            Reviewers
                                            2019-10-16
                                            Migrated from v1.4
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                            Entry version: 1

                                            Date
                                            Changes
                                            Submitters
                                            Reviewers
                                            2015-06-12
                                            Submitted
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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