BGC0000086: lasalocid biosynthetic gene cluster from Streptomyces lasaliensis
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Location: 1 - 81,959 nt. (total: 81,959 nt).
This entry is originally from NCBI GenBank AB449340.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000086
Short description lasalocid biosynthetic gene cluster from Streptomyces lasaliensis
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
AB449340.1
via
Compounds
  • lasalocid
Species Streptomyces lasaliensis [taxonomy]
References
Chemical products information
lasalocid Evidence:
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C34H53Na1O8
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BAG85014.1
 35 - 1096 (-) putative endo-1,4-b-xylanase
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    • BAG85015.1
    		 1403 - 1936 (-) hypothetical protein
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      • BAG85016.1
      • lsd1
      		 2116 - 2817 (-) hypothetical protein
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        • BAG85017.1
        • lsd2
        		 2923 - 3666 (-) putative transcriptional regulator
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          • BAG85018.1
          • lsd3
          		 4465 - 4899 (+) putative 3-oxoacyl-(acyl carrier protein) synthase
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            • BAG85019.1
            • lsd4
            		 4918 - 5697 (-) putative type II thioesterase
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              • BAG85020.1
              • lsd5
              		 5870 - 7438 (-) putative resistance protein
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                • BAG85021.1
                • lsd6
                		 7654 - 8043 (+) hypothetical protein
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                  • BAG85022.1
                  • lsd7
                  		 8222 - 8401 (-) hypothetical protein
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                    • BAG85023.1
                    • lsd8
                    		 8611 - 11334 (+) putative transcriptional regulator
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                      • BAG85024.1
                      • lsd9
                      		 11459 - 12709 (+) putative crotonyl-CoA reductase
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                        • BAG85025.1
                        • lsd10
                        		 12833 - 14560 (-) putative 3-hydroxybutyryl-CoA dehydrogenase
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                          • BAG85026.1
                          • lsd11
                          		 15129 - 29810 (+) putative polyketide synthase
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                            • BAG85027.1
                            • lsd12
                            		 29979 - 46268 (+) putative polyketide synthase
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                              • BAG85028.1
                              • lsd13
                              		 46297 - 49638 (+) putative polyketide synthase
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                                • BAG85029.1
                                • lsd14
                                		 49702 - 54645 (+) putative polyketide synthase
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                                  • BAG85030.1
                                  • lsd15
                                  		 54770 - 65809 (+) putative polyketide synthase
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                                    • BAG85031.1
                                    • lsd16
                                    		 65864 - 71578 (+) putative polyketide synthase
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                                      • BAG85032.1
                                      • lsd17
                                      		 71698 - 75510 (+) putative polyketide synthase
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                                        • BAG85033.1
                                        • lsd18
                                        		 76196 - 77614 (+) putative epoxidase
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                                          • BAG85034.1
                                          • lsd19
                                          		 77627 - 78475 (+) epoxide hydrolase
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                                            • BAG85035.1
                                            		 79065 - 79754 (+) putative serine-type D-Ala-D-Ala carboxypeptidase
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                                              • BAG85036.1
                                              		 80186 - 80605 (+) hypothetical protein
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                                                • BAG85037.1
                                                		 80651 - 81376 (+) hypothetical protein
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                                                  Biosynthesis information
                                                  Annotation changelog

                                                  Entry version: 4

                                                  Date
                                                  Changes
                                                  Submitters
                                                  Reviewers
                                                  2022-10-07
                                                  Update chemical activity to schema version 2.11
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                  Entry version: 3

                                                  Date
                                                  Changes
                                                  Submitters
                                                  Reviewers
                                                  2022-09-15
                                                  Updated bioactivity data
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                  Entry version: 2

                                                  Date
                                                  Changes
                                                  Submitters
                                                  Reviewers
                                                  2019-10-16
                                                  Migrated from v1.4
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                  Entry version: 1

                                                  Date
                                                  Changes
                                                  Submitters
                                                  Reviewers
                                                  2015-06-12
                                                  Submitted
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                  Detailed domain annotation
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