BGC0000086: lasalocid biosynthetic gene cluster from Streptomyces lasaliensis
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Location: 1 - 81,959 nt. (total: 81,959 nt).
This entry is originally from NCBI GenBank AB449340.1.

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core biosynthetic genes
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resistance
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General
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000086
Short description lasalocid biosynthetic gene cluster from Streptomyces lasaliensis
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: AB449340.1
Compounds
  • lasalocid
Species Streptomyces lasaliensis [taxonomy]
References
Chemical products information
lasalocid
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C34H53Na1O8
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BAG85014.1
35 - 1096 (-) putative endo-1,4-b-xylanase
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  • BAG85015.1
1403 - 1936 (-) hypothetical protein
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  • BAG85016.1
  • lsd1
2116 - 2817 (-) hypothetical protein
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  • BAG85017.1
  • lsd2
2923 - 3666 (-) putative transcriptional regulator
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  • BAG85018.1
  • lsd3
4465 - 4899 (+) putative 3-oxoacyl-(acyl carrier protein) synthase
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  • BAG85019.1
  • lsd4
4918 - 5697 (-) putative type II thioesterase
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  • BAG85020.1
  • lsd5
5870 - 7438 (-) putative resistance protein
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  • BAG85021.1
  • lsd6
7654 - 8043 (+) hypothetical protein
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  • BAG85022.1
  • lsd7
8222 - 8401 (-) hypothetical protein
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  • BAG85023.1
  • lsd8
8611 - 11334 (+) putative transcriptional regulator
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  • BAG85024.1
  • lsd9
11459 - 12709 (+) putative crotonyl-CoA reductase
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  • BAG85025.1
  • lsd10
12833 - 14560 (-) putative 3-hydroxybutyryl-CoA dehydrogenase
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  • BAG85026.1
  • lsd11
15129 - 29810 (+) putative polyketide synthase
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  • BAG85027.1
  • lsd12
29979 - 46268 (+) putative polyketide synthase
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  • BAG85028.1
  • lsd13
46297 - 49638 (+) putative polyketide synthase
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  • BAG85029.1
  • lsd14
49702 - 54645 (+) putative polyketide synthase
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  • BAG85030.1
  • lsd15
54770 - 65809 (+) putative polyketide synthase
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  • BAG85031.1
  • lsd16
65864 - 71578 (+) putative polyketide synthase
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  • BAG85032.1
  • lsd17
71698 - 75510 (+) putative polyketide synthase
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  • BAG85033.1
  • lsd18
76196 - 77614 (+) putative epoxidase
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  • BAG85034.1
  • lsd19
77627 - 78475 (+) epoxide hydrolase
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  • BAG85035.1
79065 - 79754 (+) putative serine-type D-Ala-D-Ala carboxypeptidase
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  • BAG85036.1
80186 - 80605 (+) hypothetical protein
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  • BAG85037.1
80651 - 81376 (+) hypothetical protein
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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