BGC0000102: mycinamicin II biosynthetic gene cluster from Micromonospora griseorubida
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Location: 1 - 58,343 nt. (total: 58,343 nt).
This entry is originally from NCBI GenBank AB089954.2.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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General
Compounds
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Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000102
Short description mycinamicin II biosynthetic gene cluster from Micromonospora griseorubida
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
AB089954.2
via
Compounds
  • mycinamicin II
Species Micromonospora griseorubida [taxonomy]
References
Chemical products information
mycinamicin II Evidence:
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C37H61N1O13
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BAC57022.1
  • mycF
 1 - 910 (-) methyltransferase
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    • BAC57023.2
    • mycCI
    		 1490 - 2641 (+) cytochrome P450
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      • BAC57024.1
      • mycCII
      		 2662 - 2886 (+) ferredxin
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        • BAC57025.1
        • mydI
        		 2883 - 3866 (+) 4-ketoreductase
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          • BAC57026.1
          • mycE
          		 3887 - 5086 (+) methyltransferase
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            • BAC57027.1
            • mycD
            		 5181 - 6443 (+) glycosyltransferase
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              • BAC57028.1
              • mycAI
              		 6720 - 19643 (+) protomycinolide IV synthase 1
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                • BAC57029.1
                • mycAII
                		 19662 - 25193 (+) protomycinolide IV synthase 2
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                  • BAC57030.1
                  • mycAIII
                  		 25213 - 36162 (+) protomycinolide IV synthase 3
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                    • BAC57031.1
                    • mycAIV
                    		 36207 - 40955 (+) protomycinolide IV synthase 4
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                      • BAC57032.1
                      • mycAV
                      		 40998 - 47210 (+) protomycinolide IV synthase 5
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                        • BAC57033.1
                        • mydD
                        		 47300 - 48448 (-) transaminase
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                          • BAC57034.1
                          • mydF
                          		 48423 - 49880 (-) reductase
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                            • BAC57035.1
                            • mydE
                            		 49819 - 51135 (-) 4-dehydratase
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                              • BAC57036.1
                              • mydG
                              		 51220 - 51945 (-) N, N-dimethyltransferase
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                                • BAC57037.1
                                • mycB
                                		 51975 - 53261 (-) glycosyltransferase
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                                  • BAC57038.1
                                  • mydC
                                  		 53286 - 54524 (-) tautomerase
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                                    • BAC57039.1
                                    • mydA
                                    		 55080 - 55961 (+) dTDP-glucose synthase
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                                      • BAC57040.1
                                      • mydH
                                      		 55958 - 56659 (+) dTDP-4-keto, 6-deoxyglucose-3-epimerase
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                                        • BAC57041.1
                                        • mydB
                                        		 56637 - 57665 (-) dTDP-glucose-4,6-dehydratase
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                                          • BAC57042.1
                                          		 57811 - >58343 (+) hypothetical protein
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                                            Biosynthesis information
                                            Annotation changelog

                                            Entry version: 4

                                            Date
                                            Changes
                                            Submitters
                                            Reviewers
                                            2022-10-07
                                            Update chemical activity to schema version 2.11
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                            Entry version: 3

                                            Date
                                            Changes
                                            Submitters
                                            Reviewers
                                            2022-09-15
                                            Updated bioactivity data
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                            Entry version: 2

                                            Date
                                            Changes
                                            Submitters
                                            Reviewers
                                            2019-10-16
                                            Migrated from v1.4
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            2019-10-16
                                            Updated compound(s) information (NPAtlas curation)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                            Entry version: 1

                                            Date
                                            Changes
                                            Submitters
                                            Reviewers
                                            2015-06-12
                                            Submitted
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            Detailed domain annotation
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