Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000103.1:
Cluster 1Polyketide1107218

BGC0000103, mycolactone biosynthetic gene cluster from Mycobacterium ulcerans. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: mycolactone
PubChem ID: 5282079
SMILES string: Copy to clipboard
Molecular formula: C44H70O9
Average molecular mass: 743.035 Da

Class-specific details

Biosynthetic class(es):
Polyketide
Polyketide synthase subclass:
Type I

Gene cluster description

mycolactone (BGC0000103). Gene Cluster 1. Biosynthetic class = Polyketide. GenBank BX649209, positions 30054-137271. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Domain annotation

Homologous known gene clusters

Literature references

1. Stinear TP et al. (2004) Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans. Proc Natl Acad Sci U S A 101(5):1345-9. doi: 10.1073/pnas.0305877101.