Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000111.1:
Cluster 1Polyketide133079

BGC0000111, neocarzilin biosynthetic gene cluster from Streptomyces carzinostaticus. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: neocarzilin

Class-specific details

Biosynthetic class(es):
Polyketide synthase subclass:
Type I

Gene cluster description

neocarzilin (BGC0000111). Gene Cluster 1. Biosynthetic class = Polyketide. GenBank AB097904. Click on genes for more information.


biosynthetic genes
transport-related genes
regulatory genes
other genes

Domain annotation

Homologous known gene clusters

Literature references

1. Otsuka M et al. (2004) Cloning, sequencing, and functional analysis of an iterative type I polyketide synthase gene cluster for biosynthesis of the antitumor chlorinated polyenone neocarzilin in "Streptomyces carzinostaticus". Antimicrob Agents Chemother 48(9):3468-76. doi: