BGC0000111 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000111 (Streptomyces carzinostaticus)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	33,079	branched-chain fatty acids	Other	100%

BGC0000111 - Region 1 - T1PKS

Download region GenBank file

Download region SVG

Location: 1 - 33,079 nt. (total: 33,079 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 33,080
Label		BGC0000111

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000111.1	0.83	Polyketide	neocarzilin A, neocarzilin B	Streptomyces carzinostaticus
BGC0001535.1	0.44	Other	branched-chain fatty acids	Streptomyces filamentosus
BGC0000041.1	0.38	Polyketide	oronofacic acid	Pseudomonas syringae
BGC0001504.1	0.31	Polyketide	amycomicin	Amycolatopsis sp. AA4
BGC0001909.1	0.31	Polyketide	strobilurin	Strobilurus tenacellus
BGC0001913.1	0.29	Polyketide	phomoidride	fungal sp. ATCC 74256
BGC0001283.1	0.28	Polyketide	arsono-polyketide	Streptomyces lividans 1326
BGC0001340.1	0.28	Polyketide	byssochlamic acid	Byssochlamys fulva
BGC0000046.1	0.27	Polyketide	depudecin	Alternaria brassicicola
BGC0001534.1	0.27	Other	branched-chain fatty acids	Streptomyces filamentosus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000111.1	0.94	Polyketide	neocarzilin A, neocarzilin B	Streptomyces carzinostaticus
BGC0001535.1	0.75	Other	branched-chain fatty acids	Streptomyces filamentosus
BGC0000041.1	0.70	Polyketide	oronofacic acid	Pseudomonas syringae
BGC0001504.1	0.65	Polyketide	amycomicin	Amycolatopsis sp. AA4
BGC0001909.1	0.64	Polyketide	strobilurin	Strobilurus tenacellus
BGC0001913.1	0.63	Polyketide	phomoidride	fungal sp. ATCC 74256
BGC0001283.1	0.62	Polyketide	arsono-polyketide	Streptomyces lividans 1326
BGC0001340.1	0.61	Polyketide	byssochlamic acid	Byssochlamys fulva
BGC0000046.1	0.61	Polyketide	depudecin	Alternaria brassicicola
BGC0001534.1	0.61	Other	branched-chain fatty acids	Streptomyces filamentosus

Similar known gene clusters

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 33079:

Rough prediction of core scaffold based on assumed PKS linker matching; tailoring reactions not taken into account

Polymer prediction:: (ccmal) + (pk)
Non-colinear ordering:: BAD38874.1 + BAD38873.1

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

BAD38873.1

PKS_AT (554..858): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; Methylmalonyl-CoA: 83.3%; Methoxymalonyl-CoA: 75.0%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 147.1
Ethylmalonyl-CoA: 124.0
Methoxymalonyl-CoA: 110.5
Malonyl-CoA: 97.7
Propionyl-CoA: 73.7
2-Methylbutyryl-CoA: 65.4
Isobutyryl-CoA: 63.5
trans-1,2-CPDA: 60.9
Benzoyl-CoA: 58.3
CHC-CoA: 54.6
Acetyl-CoA: 40.3
3-Methylbutyryl-CoA: 21.4
inactive: 16.9
fatty_acid: 14.5

BAD38874.1

PKS_AT (1810..2100): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 83.3%; Methylmalonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 188.0
inactive: 117.4
Methoxymalonyl-CoA: 69.4
Methylmalonyl-CoA: 67.6
Propionyl-CoA: 53.9
Isobutyryl-CoA: 47.8
Ethylmalonyl-CoA: 31.6
Benzoyl-CoA: 31.4
2-Methylbutyryl-CoA: 27.5
Acetyl-CoA: 19.2
CHC-CoA: 16.5
trans-1,2-CPDA: 13.9
fatty_acid: 11.7
3-Methylbutyryl-CoA: 8.8