BGC0000143: salinomycin biosynthetic gene cluster from Streptomyces albus
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 1 - 25,809 nt. (total: 25,809 nt).
This entry is originally from NCBI GenBank DQ630728.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000143
Short description salinomycin biosynthetic gene cluster from Streptomyces albus
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
DQ630728.1
via
Compounds
  • salinomycin
Species Streptomyces albus [taxonomy]
References
Chemical products information
salinomycin Evidence:
Copy SMILES
C42H70O11
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ABG02263.1
  • salA
 3 - 5183 (+) SalA
    copy AA seq
    copy Nt seq
    • ABG02264.1
    		 5287 - 14826 (+) SalB
      copy AA seq
      copy Nt seq
      • ABG02265.1
      • salRIII
      		 15072 - 15767 (-) SalRIII
        copy AA seq
        copy Nt seq
        • ABG02266.1
        • salRII
        		 16261 - 19086 (-) SalRII
          copy AA seq
          copy Nt seq
          • ABG02267.1
          • salRI
          		 19727 - 22615 (-) SalRI
            copy AA seq
            copy Nt seq
            • ABG02268.1
            • salC
            		 22810 - 24030 (-) SalC
              copy AA seq
              copy Nt seq
              • ABG02269.1
              • salD
              		 24092 - 25318 (-) SalD
                copy AA seq
                copy Nt seq
                • ABG02270.1
                • salE
                		 25630 - >25809 (+) SalE
                  copy AA seq
                  copy Nt seq
                  Biosynthesis information
                  Annotation changelog

                  Entry version: 4

                  Date
                  Changes
                  Submitters
                  Reviewers
                  2022-10-07
                  Update chemical activity to schema version 2.11
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                  Entry version: 3

                  Date
                  Changes
                  Submitters
                  Reviewers
                  2022-09-15
                  Updated bioactivity data
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                  Entry version: 2

                  Date
                  Changes
                  Submitters
                  Reviewers
                  2019-10-16
                  Migrated from v1.4
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  2019-10-16
                  Updated compound(s) information (NPAtlas curation)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                  Entry version: 1

                  Date
                  Changes
                  Submitters
                  Reviewers
                  2015-06-12
                  Submitted
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                  Detailed domain annotation
                  Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
                  A domain glossary is available here, and an explanation of the visualisation is available here.
                  Selected features only
                  Show module domains
                  Similar known gene clusters from MIBiG 4.0
                  Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                  Click on reference genes to show details of similarities to genes within the current region.
                  Click on an accession to open that entry in the MiBIG database.