BGC0000163: tetronasin biosynthetic gene cluster from Streptomyces longisporoflavus
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Location: 1 - 169,690 nt. (total: 169,690 nt).
This entry is originally from NCBI GenBank FJ462704.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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resistance
TTA codons
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Gene details
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General
Compounds
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000163
Short description tetronasin biosynthetic gene cluster from Streptomyces longisporoflavus
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: FJ462704.1
Compounds
  • tetronasin
Species Streptomyces longisporoflavus [taxonomy]
References
Chemical products information
tetronasin
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C35H54O8
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ACR50750.1
 2 - 910 (+) putative ABC transporter permease protein
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  • ACR50751.1
 1020 - 1778 (+) putative ABC transporter permease protein
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  • ACR50752.1
 1838 - 3256 (-) conserved hypothetical protein
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  • ACR50753.1
 3427 - 4326 (-) putative sugar kinase
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  • ACR50754.1
 4383 - 5339 (-) zinc-binding dehydrogenase
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  • ACR50755.1
 5369 - 6286 (-) integral membrane sugar transport protein
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  • ACR50756.1
 6283 - 7269 (-) putative ABC transporter permease protein
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  • ACR50757.1
 7266 - 8585 (-) putative multiple sugar ABC transporter solute-binding protein
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  • ACR50758.1
 8767 - 9528 (-) DeoR family transcriptional regulator
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  • ACR50759.1
 10058 - 11776 (-) putative secreted protein
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  • ACR50760.1
 11993 - 13090 (-) hypothetical protein
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  • ACR50761.1
 13457 - 14896 (+) 6-phosphogluconate 1-dehydrogenase
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  • ACR50762.1
 15322 - 15675 (-) conserved hypothetical protein
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  • ACR50763.1
 15861 - 18077 (-) periplasmic beta-glucosidase
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  • ACR50764.1
 18327 - 18683 (-) hypothetical protein
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  • ACR50765.1
 18798 - 19616 (+) hypothetical protein
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  • ACR50766.1
 19520 - 20401 (-) putative phosphoesterase
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  • ACR50767.1
 20581 - 20994 (-) hypothetical protein
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  • ACR50768.1
  • tsn1
 21304 - 22122 (+) putative E2-like acyltransferase component of pyruvate/2-oxoglutarate dehydrogenase
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  • ACR50769.1
  • tsn2
 22160 - 23455 (-) E2 dihydrolipoyl acyltransferase
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  • ACR50770.1
  • tsn3
 23448 - 24464 (-) pyruvate dehydrogenase E1 beta subunit
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  • ACR50771.1
  • tsn4
 24443 - 25480 (-) pyruvate dehydrogenase E1 alpha subunit
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  • ACR50772.1
  • tsn5
 25477 - 25803 (-) acyl carrier protein
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  • ACR50773.1
  • tsnAII
 26101 - 41511 (+) polyketide synthase
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  • ACR50774.1
  • tsnAIII
 41576 - 58468 (+) polyketide synthase
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  • ACR50775.1
  • tsnAIV
 58540 - 76650 (+) polyketide synthase
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  • ACR50776.1
  • tsnB
 76643 - 77062 (+) epoxide hydrolase
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  • ACR50777.1
  • tsn7
 77059 - 78327 (+) putative major facilitator transporter
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  • ACR50778.1
  • tsn8
 78441 - 79313 (-) methyltransferase
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  • ACR50779.1
  • tsn9
 79594 - 80646 (+) putative 3-oxoacyl-ACP synthase III
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  • ACR50780.1
  • tsnC
 80643 - 82076 (+) epoxidase
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  • ACR50781.1
  • tsn11
 82195 - 83697 (-) putative FAD-dependent oxygenase
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  • ACR50782.1
  • tsnAV
 83714 - 88375 (-) polyketide synthase
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  • ACR50783.1
  • tsn12
 88582 - 89766 (-) P450 monooxygenase
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  • ACR50784.1
  • tsn13
 90030 - 91082 (+) putative 3-oxoacyl-ACP synthase III
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  • ACR50785.1
  • tsnAI
 91916 - 107005 (-) polyketide synthase
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  • ACR50786.1
  • tsn14
 107202 - 107738 (+) putative regulatory protein
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  • ACR50787.1
  • tsn15
 108020 - 109642 (-) putative ABC transporter, membrane spanning protein
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  • ACR50788.1
  • tsn16
 109639 - 110544 (-) putative ABC transporter, ATP binding component
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  • ACR50789.1
  • tsn17
 111072 - 111842 (+) putative pathway specific activator
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  • ACR50790.1
  • tsn18
 112229 - 113113 (+) putative oxidoreductase
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  • ACR50791.1
  • tsnDIII
 113739 - 120032 (+) putative polyketide synthase
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  • ACR50792.1
  • tsn19
 120029 - 121591 (+) putative acyl-CoA synthase
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  • ACR50793.1
  • tsn20
 121604 - 122875 (+) putative P450 monooxygenase
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  • ACR50794.1
  • tsn20a
 123140 - 123907 (-) putative type II thioesterase
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  • ACR50795.1
  • tsnDII
 123948 - 128456 (-) putative polyketide synthase
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  • ACR50796.1
  • tsnDI
 128581 - 136011 (-) putative polyketide synthase
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  • ACR50797.1
  • tsn21
 136385 - 138136 (+) acyltransferase
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  • ACR50798.1
  • tsn22
 138180 - 138929 (-) putative TetR-family transcriptional regulator
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  • ACR50799.1
  • tsn23
 138794 - 139933 (-) putative membrane protein
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  • ACR50800.1
  • tsn24
 140465 - 143221 (-) putative LuxR-family transcriptional regulator
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  • ACR50801.1
  • tsn25
 143949 - 144698 (-) putative methyltransferase
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
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