BGC0000167: vicenistatin biosynthetic gene cluster from Streptomyces halstedii
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Location: 1 - 64,492 nt. (total: 64,492 nt).
This entry is originally from NCBI GenBank AB086653.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000167
Short description vicenistatin biosynthetic gene cluster from Streptomyces halstedii
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: AB086653.1
Compounds
  • vicenistatin
Species Streptomyces halstedii [taxonomy]
References
Chemical products information
vicenistatin
Copy SMILES
C30H48N2O4
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BAD08354.1
  • vinR1
1 - 367 (-) putative transcriptional activator
copy AA seq
copy Nt seq
  • BAD08355.1
  • vinA
695 - 1762 (+) dTDP-glucose synthase
copy AA seq
copy Nt seq
  • BAD08356.1
  • vinB
1759 - 2730 (+) dTDP-glucose 4,6-dehydratase
copy AA seq
copy Nt seq
  • BAD08357.1
  • vinC
2790 - 4049 (+) glycosyltransferase
copy AA seq
copy Nt seq
  • BAD08358.1
  • vinP2
4412 - 11194 (+) polyketide synthase modules 4
copy AA seq
copy Nt seq
  • BAD08359.1
  • vinP3
11260 - 21348 (+) polyketide synthase modules 5-6
copy AA seq
copy Nt seq
  • BAD08360.1
  • vinP4
21411 - 32837 (+) polyketide synthase modules 7-8
copy AA seq
copy Nt seq
  • BAD08361.1
  • vinG
33262 - 33972 (-) N-methyltransferase
copy AA seq
copy Nt seq
  • BAD08362.1
  • vinF
33980 - 35137 (-) aminotransferase
copy AA seq
copy Nt seq
  • BAD08363.1
  • vinD
35332 - 36801 (+) dTDP-4-keto-6-deoxyglucose 2,3-dehydratase
copy AA seq
copy Nt seq
  • BAD08364.1
  • vinE
36855 - 37841 (+) dTDP-4-keto-6-deoxyhexose 2,3-reductase
copy AA seq
copy Nt seq
  • BAD08365.1
  • vinH
38001 - 38498 (+) glutamate mutase S-chain
copy AA seq
copy Nt seq
  • BAD08366.1
  • vinI
38495 - 39904 (+) glutamate mutase E-chain
copy AA seq
copy Nt seq
  • BAD08367.1
  • vinJ
39990 - 40889 (+) proline iminopeptidase
copy AA seq
copy Nt seq
  • BAD08368.1
  • vinK
40886 - 41869 (+) malonyl-CoA-[acyl-carrier-protein] transacylase
copy AA seq
copy Nt seq
  • BAD08369.1
  • vinL
41987 - 42235 (+) acyl-carrier-protein
copy AA seq
copy Nt seq
  • BAD08370.1
  • vinM
42289 - 43863 (+) non-ribosomal peptide synthetase
copy AA seq
copy Nt seq
  • BAD08371.1
  • vinN
44156 - 45592 (+) non-ribosomal peptide synthetase
copy AA seq
copy Nt seq
  • BAD08372.1
  • vinO
45589 - 46833 (+) decarboxylase
copy AA seq
copy Nt seq
  • BAD08373.1
  • vinP1
47012 - 64492 (+) polyketide synthase modules 1-3
copy AA seq
copy Nt seq
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.