BGC0000170 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000170 (Aspergillus niger ATCC 1015)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	23,998	patulin	Polyketide:Iterative type I	26%

BGC0000170 - Region 1 - T1PKS

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Location: 1 - 23,998 nt. (total: 23,998 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 23,999
Label		BGC0000170

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000170.1	0.67	Polyketide	yanuthone D	Aspergillus niger ATCC 1015
BGC0001909.1	0.31	Polyketide	strobilurin	Strobilurus tenacellus
BGC0001858.1	0.27	Polyketide	alternapyrone B, alternapyrone C, alternapyrone D, alternapyrone E, alternapyrone F	Parastagonospora nodorum SN15
BGC0001475.1	0.26	Polyketide	aspterric acid	Aspergillus terreus NIH2624
BGC0001969.1	0.26	Terpene	asperterpenoid A	Talaromyces wortmannii
BGC0001280.1	0.25	Polyketide	betaenone C, betaenone A	Phoma betae
BGC0001264.1	0.25	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae
BGC0001276.1	0.24	Polyketide	6-methylsalicyclic acid	Aspergillus terreus
BGC0001275.1	0.24	Polyketide	6-methylsalicyclic acid	Glarea lozoyensis
BGC0001068.1	0.24	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000170.1	0.87	Polyketide	yanuthone D	Aspergillus niger ATCC 1015
BGC0001909.1	0.65	Polyketide	strobilurin	Strobilurus tenacellus
BGC0001858.1	0.61	Polyketide	alternapyrone B, alternapyrone C, alternapyrone D, alternapyrone E, alternapyrone F	Parastagonospora nodorum SN15
BGC0001475.1	0.60	Polyketide	aspterric acid	Aspergillus terreus NIH2624
BGC0001969.1	0.60	Terpene	asperterpenoid A	Talaromyces wortmannii
BGC0001280.1	0.58	Polyketide	betaenone C, betaenone A	Phoma betae
BGC0001264.1	0.58	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae
BGC0001276.1	0.57	Polyketide	6-methylsalicyclic acid	Aspergillus terreus
BGC0001275.1	0.57	Polyketide	6-methylsalicyclic acid	Glarea lozoyensis
BGC0001068.1	0.57	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.

Similar known gene clusters

Module view

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 23998:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Me-ccmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ASPNIDRAFT_44965

PKS_AT (586..877): mmal

ATSignature: Methylmalonyl-CoA, Malonyl-CoA

Top 3 matches:: Methylmalonyl-CoA: 75.0%; Malonyl-CoA: 75.0%; Ethylmalonyl-CoA: 70.8%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 111.9
Ethylmalonyl-CoA: 94.8
Methoxymalonyl-CoA: 91.0
Isobutyryl-CoA: 67.1
Malonyl-CoA: 58.2
trans-1,2-CPDA: 46.4
Benzoyl-CoA: 44.0
Propionyl-CoA: 40.9
2-Methylbutyryl-CoA: 40.5
Acetyl-CoA: 31.8
fatty_acid: 30.0
CHC-CoA: 16.5
3-Methylbutyryl-CoA: 16.1
inactive: 10.4