BGC0000190: A-74528 biosynthetic gene cluster from Streptomyces sp. SANK 61196
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Location: 1 - 28,713 nt. (total: 28,713 nt).
This entry is originally from NCBI GenBank GU937384.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000190
Short description A-74528 biosynthetic gene cluster from Streptomyces sp. SANK 61196
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
GU937384.1
via
Compounds
  • A-74528
Species Streptomyces sp. SANK 61196 [taxonomy]
References
Chemical products information
A-74528 Evidence:
Copy SMILES
C30H24O11
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ADG86308.1
  • san1
 1 - 1695 (-) acyl-CoA decarboxylase
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    • ADG86309.1
    • san2
    		 1791 - 2819 (+) acyl-ACP-thioesterase
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      • ADG86310.1
      • san3
      		 2780 - 5578 (-) quinone-forming monooxygenase
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        • ADG86311.1
        • sanC
        		 5690 - 6430 (+) 3-ketoacyl ACP-reductase
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          • ADG86312.1
          • sanT
          		 6513 - 8048 (+) peptide transporter
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            • ADG86313.1
            • sanD
            		 8196 - 8516 (+) polyketide cyclase
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              • ADG86314.1
              • sanE
              		 8648 - 9073 (+) polyketide cyclase
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                • ADG86315.1
                • sanF
                		 9070 - 10335 (+) ketosynthase
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                  • ADG86316.1
                  • sanG
                  		 10332 - 11603 (+) chain length factor
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                    • ADG86317.1
                    • sanH
                    		 11737 - 11994 (+) acyl carrier protein
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                      • ADG86318.1
                      • sanI
                      		 11996 - 12451 (+) polyketide cyclase/aromatase
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                        • ADG86319.1
                        • sanJ
                        		 12448 - 12792 (+) monooxygenase
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                          • ADG86320.1
                          • sanK
                          		 12789 - 13223 (+) monooxygenase
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                            • ADG86321.1
                            • sanL
                            		 13447 - 14187 (-) monooxygenase
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                              • ADG86322.1
                              • sanM
                              		 14316 - 14762 (-) hydroxylase
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                                • ADG86323.1
                                • sanM1
                                		 14985 - 15452 (+) hydroxylase
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                                  • ADG86324.1
                                  • sanN
                                  		 15654 - 16706 (+) O-methyltransferase
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                                    • ADG86325.1
                                    • sanO
                                    		 16807 - 17556 (+) ketoreductase
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                                      • ADG86326.1
                                      • sanP
                                      		 17549 - 17869 (+) monooxygenase
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                                        • ADG86327.1
                                        • sanQ
                                        		 17866 - 18183 (+) monooxygenase
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                                          • ADG86328.1
                                          • sanS
                                          		 18306 - 19313 (-) 3-ketoacyl ACP-synthase
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                                            • ADG86329.1
                                            • sanT1
                                            		 19331 - 20347 (-) transporter
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                                              • ADG86330.1
                                              • sanX
                                              		 20585 - 20890 (+) hypothetical protein
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                                                • ADG86331.1
                                                • sanR
                                                		 21180 - 21611 (-) regulator
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                                                  • ADG86332.1
                                                  • sanU
                                                  		 21853 - 22293 (+) hypothetical protein
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                                                    • ADG86333.1
                                                    • sanV
                                                    		 22412 - 24316 (+) asparagine synthetase
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                                                      • ADG86334.1
                                                      • sanR1
                                                      		 24542 - 26374 (-) regulator
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                                                        • ADG86335.1
                                                        • sanT2
                                                        		 26608 - 28140 (+) transporter
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                                                          • ADG86336.1
                                                          • sanW
                                                          		 28234 - 28713 (+) phosphopantetheinyl transferase
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                                                            Biosynthesis information
                                                            Annotation changelog

                                                            Entry version: 4

                                                            Date
                                                            Changes
                                                            Submitters
                                                            Reviewers
                                                            2022-10-07
                                                            Update chemical activity to schema version 2.11
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                            Entry version: 3

                                                            Date
                                                            Changes
                                                            Submitters
                                                            Reviewers
                                                            2022-09-15
                                                            Updated bioactivity data
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                            Entry version: 2

                                                            Date
                                                            Changes
                                                            Submitters
                                                            Reviewers
                                                            2019-10-16
                                                            Migrated from v1.4
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                            2019-10-16
                                                            Updated compound(s) information (NPAtlas curation)
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                            Entry version: 1

                                                            Date
                                                            Changes
                                                            Submitters
                                                            Reviewers
                                                            2015-06-12
                                                            Submitted
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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