BGC0000209: chlortetracycline biosynthetic gene cluster from Kitasatospora aureofaciens
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Location: 1 - 41,528 nt. (total: 41,528 nt).
This entry is originally from NCBI GenBank HM627755.1.

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core biosynthetic genes
additional biosynthetic genes
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resistance
TTA codons
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Gene details
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General
Compounds
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Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000209
Short description chlortetracycline biosynthetic gene cluster from Kitasatospora aureofaciens
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
HM627755.1
via
Compounds
  • chlortetracycline
Species Kitasatospora aureofaciens [taxonomy]
References
Chemical products information
chlortetracycline Evidence:
Copy SMILES
C22H23Cl1N2O8
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AEI98637.1
  • ctc9
1 - 284 (-) Ctc9
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    • AEI98638.1
    • ctc8
    403 - 1644 (-) Ctc8
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      • AEI98639.1
      • ctc7
      1986 - 2753 (+) Ctc7
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        • AEI98640.1
        • ctc6
        2787 - 3569 (-) Ctc6
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          • AEI98641.1
          • ctc5
          3691 - 5052 (-) Ctc5
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            • AEI98642.1
            • ctc4
            5228 - 6982 (+) Ctc4
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              • AEI98643.1
              • ctc3
              7048 - 8547 (+) Ctc3
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                • AEI98644.1
                • ctcA
                9658 - 10305 (+) CtcA
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                  • AEI98645.1
                  • ctcB
                  10418 - 11227 (-) CtcB
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                    • AEI98646.1
                    • ctcC
                    11579 - 13561 (+) CtcC
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                      • AEI98647.1
                      • ctcD
                      13635 - 14405 (-) CtcD
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                        • AEI98648.1
                        • ctcE
                        14392 - 16017 (-) CtcE
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                          • AEI98649.1
                          • ctcF
                          16010 - 16948 (-) CtcF
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                            • AEI98650.1
                            • ctcG
                            17039 - 17827 (-) CtcG
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                              • AEI98651.1
                              • ctcH
                              18011 - 18478 (+) CtcH
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                                • AEI98652.1
                                • ctcI
                                18491 - 20044 (+) CtcI
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                                  • AEI98653.1
                                  • ctcJ
                                  20088 - 20378 (+) CtcJ
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                                    • AEI98654.1
                                    • ctcK
                                    20392 - 21429 (+) CtcK
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                                      • AEI98655.1
                                      • ctcL
                                      21580 - 22671 (-) CtcL
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                                        • AEI98656.1
                                        • ctcM
                                        22668 - 23090 (-) CtcM
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                                          • AEI98657.1
                                          • ctcN
                                          23255 - 24727 (+) CtcN
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                                            • AEI98658.1
                                            • ctcO
                                            24756 - 25790 (+) CtcO
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                                              • AEI98659.1
                                              • ctcP
                                              25808 - 27475 (+) CtcP
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                                                • AEI98660.1
                                                • ctcQ
                                                27557 - 28132 (-) CtcQ
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                                                  • AEI98661.1
                                                  • ctcR
                                                  28350 - 29882 (-) CtcR
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                                                    • AEI98662.1
                                                    • ctcS
                                                    30019 - 30516 (+) CtcS
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                                                      • AEI98663.1
                                                      • ctcT
                                                      30500 - 32329 (-) CtcT
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                                                        • AEI98664.1
                                                        • ctcU
                                                        32332 - 32586 (-) CtcU
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                                                          • AEI98665.1
                                                          • ctcV
                                                          32656 - 33861 (-) CtcV
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                                                            • AEI98666.1
                                                            • ctcW
                                                            33858 - 35141 (-) CtcW
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                                                              • AEI98667.1
                                                              • ctcX
                                                              35422 - 36666 (+) CtcX
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                                                                • AEI98668.1
                                                                • ctcY
                                                                36663 - 37985 (+) CtcY
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                                                                  • AEI98669.1
                                                                  • ctcZ
                                                                  38489 - 39532 (-) CtcZ
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                                                                    • AEI98670.1
                                                                    • ctc1
                                                                    39757 - 40455 (-) Ctc1
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                                                                      • AEI98671.1
                                                                      • ctc2
                                                                      40576 - >41526 (-) Ctc2
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                                                                        Biosynthesis information
                                                                        Annotation changelog

                                                                        Entry version: 4

                                                                        Date
                                                                        Changes
                                                                        Submitters
                                                                        Reviewers
                                                                        Update chemical activity to schema version 2.11
                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                        Entry version: 3

                                                                        Date
                                                                        Changes
                                                                        Submitters
                                                                        Reviewers
                                                                        Updated bioactivity data
                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                        Entry version: 2

                                                                        Date
                                                                        Changes
                                                                        Submitters
                                                                        Reviewers
                                                                        Migrated from v1.4
                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                        Entry version: 1

                                                                        Date
                                                                        Changes
                                                                        Submitters
                                                                        Reviewers
                                                                        Submitted
                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                        Detailed domain annotation
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